Professor | Xiaohua Hu | Asia Growth Partners

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Name	Xiaohua Hu
Contact Information	xhhu@fudan.edu.cn
Language ability	English, Chinese
Province	Shanghai

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Name

Xiaohua Hu

Contact Information

xhhu@fudan.edu.cn

Language ability

English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Life Sciences
Academic Background & Achievements	2006 Ph.D. in Genetics: Fudan University Communication review expert for the Youth Fund and General Projects of the National Foundation of China Expert of the Ministry of Education for spot check review of postgraduate thesis Expert for inter-school review of postgraduate thesis
Work Experience	2006-2010 - Fudan University - Research Assistant at the Institutes of Biomedical Sciences 2011-present - Fudan University - Associate Professor at the School of Life Sciences 2018-2020 - Cincinnati Children’s Hospital Medical Center - Visiting Scientist
Awards	Fosun medical scholarship (2016) Outstanding teacher of the School of Life Sciences (2013, 2014)

University/Lab Affiliation and Title

Fudan University

Faculty

Life Sciences

Academic Background & Achievements

2006 Ph.D. in Genetics: Fudan University
Communication review expert for the Youth Fund and General Projects of the National Foundation of China
Expert of the Ministry of Education for spot check review of postgraduate thesis
Expert for inter-school review of postgraduate thesis

Work Experience

2006-2010 - Fudan University - Research Assistant at the Institutes of Biomedical Sciences
2011-present - Fudan University - Associate Professor at the School of Life Sciences
2018-2020 - Cincinnati Children’s Hospital Medical Center - Visiting Scientist

Awards

Fosun medical scholarship (2016)
Outstanding teacher of the School of Life Sciences (2013, 2014)

Areas of Focus	Molecular mechanisms of lung cancer and brain tumors Driver genes identification and molecular mechanisms of tumorigenesis Mechanism of abnormal phase separation of mutant proteins and anti-tumor small molecule drugs
Publications	Nuclear condensates of YAP fusion proteins alter transcription to drive ependymoma tumorigenesis, X Hu, X Wu, et al., 2023 Single-cell transcriptomic analysis of the tumor ecosystems underlying initiation and progression of papillary thyroid carcinoma, Pu W, …, Hu X, et al., 2021 Identification of the copy number variant biomarkers for breast cancer subtypes, X Pan, XH Hu, et al., 2019 Downregulation of DNMT3A by miR-708-5p inhibits lung cancer stem cell-like phenotypes through repressing Wnt/β-catenin signaling, T Liu, X Wu, T Chen, Z Luo, X Hu, 2018 Gene expression differences among different MSI statuses in colorectal cancer, Chen L, Pan X, Hu X, Zhang YH, Wang S, Huang T, Cai YD, 2018 Amn1 governs post-mitotic cell separation in Saccharomyces cerevisiae, O Fang, X Hu*, et al., 2018 miR-194 suppresses metastasis of non-small cell lung cancer through regulating expression of BMP1 and p27kip1, X Wu, T Liu, O Fang, LJ Leach，X Hu#, Z Luo#, 2014 3’ Untranslated Regions Mediate Transcriptional Interference Between Convergent Genes Both Locally and Ectopically in Saccharomyces cerevisiae, L Wang, N Jiang, L Wang, O Fang, Lindsey J. Leach, X Hu#, Z Luo#, 2014

Areas of Focus

Molecular mechanisms of lung cancer and brain tumors
Driver genes identification and molecular mechanisms of tumorigenesis
Mechanism of abnormal phase separation of mutant proteins and anti-tumor small molecule drugs

Publications

Nuclear condensates of YAP fusion proteins alter transcription to drive ependymoma tumorigenesis, X Hu, X Wu, et al., 2023
Single-cell transcriptomic analysis of the tumor ecosystems underlying initiation and progression of papillary thyroid carcinoma, Pu W, …, Hu X, et al., 2021
Identification of the copy number variant biomarkers for breast cancer subtypes, X Pan*, XH Hu*, et al., 2019
Downregulation of DNMT3A by miR-708-5p inhibits lung cancer stem cell-like phenotypes through repressing Wnt/β-catenin signaling, T Liu, X Wu, T Chen, Z Luo, X Hu, 2018
Gene expression differences among different MSI statuses in colorectal cancer, Chen L*, Pan X*, Hu X*, Zhang YH, Wang S, Huang T, Cai YD, 2018
Amn1 governs post-mitotic cell separation in Saccharomyces cerevisiae, O Fang*, X Hu*, et al., 2018
miR-194 suppresses metastasis of non-small cell lung cancer through regulating expression of BMP1 and p27kip1, X Wu, T Liu, O Fang, LJ Leach，X Hu#, Z Luo#, 2014
3’ Untranslated Regions Mediate Transcriptional Interference Between Convergent Genes Both Locally and Ectopically in Saccharomyces cerevisiae, L Wang, N Jiang, L Wang, O Fang, Lindsey J. Leach, X Hu#, Z Luo#, 2014

Lung Cancer Brain Tumors Molecular Genetics Cell Biology Mouse Models Bioinformatics Driver Genes Tumorigenesis Phase Separation Small Molecule Drugs

Lu Dongdong - Tongji University

Qin Wang - Shanghai Normal University

Yeguang Chen - Tsinghua University

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