Professor | Huang Guanghua | Asia Growth Partners

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Name	Huang Guanghua
Contact Information	huanggh@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Huang Guanghua

Contact Information

huanggh@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Life Sciences
Academic Background & Achievements	1999 - Bachelor's Degree: Southwest Agricultural University 2006 - Ph.D.: Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences Postdoctoral Research: Wistar Institute and University of Iowa 2012 - Selected for the 'Recruitment Program of Global Experts' by the Chinese Academy of Sciences 2013 - National Science Fund for Excellent Young Scholars 2016 - National Science Fund for Distinguished Young Scholars
Work Experience	Researcher: Institute of Microbiology, Chinese Academy of Sciences Special Researcher: Chinese Academy of Sciences Professor: University of Chinese Academy of Sciences
Awards	National Science Fund for Excellent Young Scholars (2013) National Science Fund for Distinguished Young Scholars (2016)

University/Lab Affiliation and Title

Fudan University

Faculty

Life Sciences

Academic Background & Achievements

1999 - Bachelor's Degree: Southwest Agricultural University
2006 - Ph.D.: Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
Postdoctoral Research: Wistar Institute and University of Iowa
2012 - Selected for the 'Recruitment Program of Global Experts' by the Chinese Academy of Sciences
2013 - National Science Fund for Excellent Young Scholars
2016 - National Science Fund for Distinguished Young Scholars

Work Experience

Researcher: Institute of Microbiology, Chinese Academy of Sciences
Special Researcher: Chinese Academy of Sciences
Professor: University of Chinese Academy of Sciences

Awards

National Science Fund for Excellent Young Scholars (2013)
National Science Fund for Distinguished Young Scholars (2016)

Areas of Focus	Candida Morphogenesis and Pathogenicity Regulation Fungal-Host Interaction Mechanisms Identification, Drug Resistance Mechanisms, and Treatment Strategies for Clinical Pathogens
Publications	Genetic regulation of the development of mating projections in Candida albicans, Liang W, Guan G, Li C, Nobile CJ, Tao L, Huang, G, 2020 Experimental evolution identifies adaptive aneuploidy as a mechanism of fluconazole resistance in Candida auris, Bing J, Hu T, Zheng Q, Muñoz JF, Cuomo CA, Huang, G, 2020 Candida auris: Epidemiology, biology, antifungal resistance, and virulence, Du H, Bing J, Hu T, Ennis CL, Nobile CJ, Huang, G, 2020 Environment-induced same-sex mating in the yeast Candida albicans through the Hsf1-Hsp90 pathway, Guan G, Tao L, Yue H, Liang W, Gong J, Bing J, Zheng Q, Veri AO, Fan S, Robbins N, Cowen LE, Huang, G, 2019 Filamentation in Candida auris, an emerging fungal pathogen of humans: passage through the mammalian body induces a heritable phenotypic switch, Yue H, Bing J, Zheng Q, Zhang Y, Hu T, Du H, Wang H, Huang, G, 2018 A coupled process of same- and opposite-sex mating generates polyploidy and genetic diversity in Candida tropicalis, Du H, Zheng Q, Bing J, Bennett RJ, Huang G, 2018 Integration of the tricarboxylic acid (TCA) cycle with cAMP signaling and Sfl2 pathways in the regulation of CO2 sensing and hyphal development in Candida albicans, Tao L, Zhang Y, Fan S, Nobile CJ, Guan G, Huang, G, 2017 N-Acetylglucosamine-Induced Cell Death in Candida albicans and Its Implications for Adaptive Mechanisms of Nutrient Sensing in Yeasts, Du, H., Guan, G., Li, X., Gulati, M., Tao, L., Cao, C., Johnson, A.D., Nobile, C.J., and Huang, G, 2015 Discovery of a 'white-gray-opaque' tristable phenotypic switching system in candida albicans: roles of non-genetic diversity in host adaptation, Tao, L., Du, H., Guan, G., Dai, Y., Nobile, C.J., Liang, W., Cao, C., Zhang, Q., Zhong, J., and Huang, G, 2014 White-opaque switching in natural MTLa/alpha isolates of Candida albicans: evolutionary implications for roles in host adaptation, pathogenesis, and sex, Xie, J., Tao, L., Nobile, C.J., Tong, Y., Guan, G., Sun, Y., Cao, C., Hernday, A.D., Johnson, A.D., Zhang, L., Bai, F-Y, Huang, G, 2013 The transcription factor Flo8 mediates CO2 sensing in the human fungal pathogen Candida albicans, Du, H., Guan, G., Xie, J., Cottier, F., Sun, Y., Jia, W., Muhlschlegel, F.A., and Huang, G*, 2012

Areas of Focus

Candida Morphogenesis and Pathogenicity Regulation
Fungal-Host Interaction Mechanisms
Identification, Drug Resistance Mechanisms, and Treatment Strategies for Clinical Pathogens

Publications

Genetic regulation of the development of mating projections in Candida albicans, Liang W, Guan G, Li C, Nobile CJ, Tao L, Huang, G*, 2020
Experimental evolution identifies adaptive aneuploidy as a mechanism of fluconazole resistance in Candida auris, Bing J, Hu T, Zheng Q, Muñoz JF, Cuomo CA, Huang, G*, 2020
Candida auris: Epidemiology, biology, antifungal resistance, and virulence, Du H, Bing J, Hu T, Ennis CL, Nobile CJ, Huang, G*, 2020
Environment-induced same-sex mating in the yeast Candida albicans through the Hsf1-Hsp90 pathway, Guan G, Tao L, Yue H, Liang W, Gong J, Bing J, Zheng Q, Veri AO, Fan S, Robbins N, Cowen LE, Huang, G*, 2019
Filamentation in Candida auris, an emerging fungal pathogen of humans: passage through the mammalian body induces a heritable phenotypic switch, Yue H, Bing J, Zheng Q, Zhang Y, Hu T, Du H, Wang H, Huang, G*, 2018
A coupled process of same- and opposite-sex mating generates polyploidy and genetic diversity in Candida tropicalis, Du H*, Zheng Q, Bing J, Bennett RJ, Huang G, 2018
Integration of the tricarboxylic acid (TCA) cycle with cAMP signaling and Sfl2 pathways in the regulation of CO2 sensing and hyphal development in Candida albicans, Tao L, Zhang Y, Fan S, Nobile CJ, Guan G, Huang, G*, 2017
N-Acetylglucosamine-Induced Cell Death in Candida albicans and Its Implications for Adaptive Mechanisms of Nutrient Sensing in Yeasts, Du, H., Guan, G., Li, X., Gulati, M., Tao, L., Cao, C., Johnson, A.D., Nobile, C.J., and Huang, G*, 2015
Discovery of a 'white-gray-opaque' tristable phenotypic switching system in candida albicans: roles of non-genetic diversity in host adaptation, Tao, L., Du, H., Guan, G., Dai, Y., Nobile, C.J., Liang, W., Cao, C., Zhang, Q., Zhong, J., and Huang, G*, 2014
White-opaque switching in natural MTLa/alpha isolates of Candida albicans: evolutionary implications for roles in host adaptation, pathogenesis, and sex, Xie, J., Tao, L., Nobile, C.J., Tong, Y., Guan, G., Sun, Y., Cao, C., Hernday, A.D., Johnson, A.D., Zhang, L., Bai, F-Y, Huang, G*, 2013
The transcription factor Flo8 mediates CO2 sensing in the human fungal pathogen Candida albicans, Du, H., Guan, G., Xie, J., Cottier, F., Sun, Y., Jia, W., Muhlschlegel, F.A., and Huang, G*, 2012

Candida Morphogenesis Pathogenicity Regulation Fungal Host Interaction Drug Resistance Clinical Pathogens Treatment Strategies

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