Professor | Ling Chen | Asia Growth Partners

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Name	Ling Chen
Contact Information	lingchenchina@fudan.edu.cn
Language ability	English, Chinese
Province	Shanghai

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Name

Ling Chen

Contact Information

lingchenchina@fudan.edu.cn

Language ability

English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Life Sciences
Academic Background & Achievements	2007 - Bachelor's Degree: Fudan University, School of Life Sciences 2011 - Ph.D.: University of Florida, Medical Genetics 2016 - Shanghai Sailing Program Award 2016 - Distinguished Professor of the Oriental Scholar Program 2020 - Renewal of the Oriental Scholar Tracking Program Published over 40 SCI papers as first or corresponding author
Work Experience	Post-2011 - University of Florida - Postdoctoral Researcher, Assistant Professor, Associate Professor 2016-Present - Fudan University - Researcher
Awards	2016 - Shanghai Sailing Program Award 2016 - Distinguished Professor of the Oriental Scholar Program 2020 - Renewal of the Oriental Scholar Tracking Program

University/Lab Affiliation and Title

Fudan University

Faculty

Life Sciences

Academic Background & Achievements

2007 - Bachelor's Degree: Fudan University, School of Life Sciences
2011 - Ph.D.: University of Florida, Medical Genetics
2016 - Shanghai Sailing Program Award
2016 - Distinguished Professor of the Oriental Scholar Program
2020 - Renewal of the Oriental Scholar Tracking Program
Published over 40 SCI papers as first or corresponding author

Work Experience

Post-2011 - University of Florida - Postdoctoral Researcher, Assistant Professor, Associate Professor
2016-Present - Fudan University - Researcher

Awards

2016 - Shanghai Sailing Program Award
2016 - Distinguished Professor of the Oriental Scholar Program
2020 - Renewal of the Oriental Scholar Tracking Program

Areas of Focus	Basic Biology of Adeno-Associated Virus and its Vectors Precise Induction of Gene Expression by rAAV Vectors Cancer Gene Therapy
Publications	Hypoxia-induced exosomes facilitate lung pre-metastatic niche formation in hepatocellular carcinoma through the miR-4508-RFX1-IL17A-p38 MAPK-NF-κB pathway, Wentao Jia, Shufang Liang, Wanfu Lin, Shu Li, Jiaying Yuan, Mingming Jin, Shuchang Nie, Ya'ni Zhang, Xiaofeng Zhai, Liping Zhou, Changquan Ling, Binbin Cheng, Chen Ling, 2023 Improved Gene Therapy for MFRP Deficiency-Mediated Retinal Degeneration by Knocking Down Endogenous Bicistronic Mfrp and Ctrp5 Transcript, Xiao Tian, Qingyun Zheng, Jinyan Xie, Qinlinglan Zhou, Letong Liang, Guotong Xu, Hongyan Chen, Chen Ling, Daru Lu, 2023 Sphingosine-1-phosphate transporter spinster homologue 2 is essential for iron-regulated metastasis of hepatocellular carcinoma, Min Li, Yuxiao Tang, Dongyao Wang, Xiaofeng Zhai, Hui Shen, Chen Zhong, Man Yao, Aiguo Jin, Zhengjun Zhou, Shaolai Zhou, Jia Fan, Chang-quan Ling, Chen Ling, 2022 Low endotoxin E. coli strain-derived plasmids reduced rAAV vector-mediated immune responses both in vitro and in vivo, Qingyun Zheng, Tianyi Wang, Xiangying Zhu, Xiao Tian, Chen Zhong, Guolin Chang, Gai Ran, Yilin Xie, Bing Zhao, Liqing Zhu, Chen Ling, 2021 Hepatocyte-specific HNF4α/miR-122 pathway contributes to the iron-overload mediated hepatic inflammation, Min Li, Yuxiao Tang, Lusha Wu, Fengfeng Mo, Xin Wang, Hongxia Li, Ruirui Qi, Hongwei Zhang, Arun Srivastava, Chen Ling, 2017

Areas of Focus

Basic Biology of Adeno-Associated Virus and its Vectors
Precise Induction of Gene Expression by rAAV Vectors
Cancer Gene Therapy

Publications

Hypoxia-induced exosomes facilitate lung pre-metastatic niche formation in hepatocellular carcinoma through the miR-4508-RFX1-IL17A-p38 MAPK-NF-κB pathway, Wentao Jia, Shufang Liang, Wanfu Lin, Shu Li, Jiaying Yuan, Mingming Jin, Shuchang Nie, Ya'ni Zhang, Xiaofeng Zhai, Liping Zhou, Changquan Ling, Binbin Cheng, Chen Ling, 2023
Improved Gene Therapy for MFRP Deficiency-Mediated Retinal Degeneration by Knocking Down Endogenous Bicistronic Mfrp and Ctrp5 Transcript, Xiao Tian, Qingyun Zheng, Jinyan Xie, Qinlinglan Zhou, Letong Liang, Guotong Xu, Hongyan Chen, Chen Ling, Daru Lu, 2023
Sphingosine-1-phosphate transporter spinster homologue 2 is essential for iron-regulated metastasis of hepatocellular carcinoma, Min Li, Yuxiao Tang, Dongyao Wang, Xiaofeng Zhai, Hui Shen, Chen Zhong, Man Yao, Aiguo Jin, Zhengjun Zhou, Shaolai Zhou, Jia Fan, Chang-quan Ling, Chen Ling, 2022
Low endotoxin E. coli strain-derived plasmids reduced rAAV vector-mediated immune responses both in vitro and in vivo, Qingyun Zheng, Tianyi Wang, Xiangying Zhu, Xiao Tian, Chen Zhong, Guolin Chang, Gai Ran, Yilin Xie, Bing Zhao, Liqing Zhu, Chen Ling, 2021
Hepatocyte-specific HNF4α/miR-122 pathway contributes to the iron-overload mediated hepatic inflammation, Min Li, Yuxiao Tang, Lusha Wu, Fengfeng Mo, Xin Wang, Hongxia Li, Ruirui Qi, Hongwei Zhang, Arun Srivastava, Chen Ling, 2017

Adeno-Associated Virus Vectors Capsid Protein Optimization Quality Control Immune Response Gene Expression Iron Response Elements Transcription Translation

Yu Qingbo - Shanghai Normal University

Yu Lan Zhao - East China Normal University

Wenyang Li - Southern University of Science and Technology

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