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Lu Daru
Life Science
Fudan University
Shanghai
Language: Chinese, English
Gene Editing
Gene Therapy
Hemophilia
Thalassemia
Pathogenic Genes
Molecular Mechanisms
Birth Defects
Congenital Hypothyroidism
Multiplex Gene Detection
Low-Frequency Mutation Detection
Areas of Focus
- Gene Editing and Gene Therapy
- Genetic Diseases
- Birth Defects
- Molecular Detection and Gene Diagnosis
- Non-invasive Prenatal Testing for Monogenic Genetic Diseases
- Third-generation IVF Gene Testing
Work Experience
- 1996-present - Fudan University - Lecturer, Associate Professor, Professor, Distinguished Professor, Vice Dean of the School of Life Sciences
Academic Background & Achievements
- 1984-1988 Bachelor's Degree: Fudan University
- 1996 PhD in Genetics: Fudan University
- Achievement: Director of the Gene Technology Engineering Research Center of the Ministry of Education
- Achievement: Director of the National Health Commission Key Laboratory of Birth Defects and Reproductive Health
- Achievement: Executive Director/Deputy Secretary-General of the Chinese Genetics Society
- Achievement: Executive Director of the China Eugenics Association
- Achievement: Chairman of the Shanghai Genetics Society
- Achievement: Vice Chairman of the Shanghai Anthropology Society
- Achievement: Vice Chairman of the Shanghai Bioengineering Society
Publications
- Two novel genetic variants in the STK38L and RAB27A genes are associated with glioma susceptibility, Chen H, Chen G, Li G, Zhang S, Chen H, Chen Y, Duggan D, Hu Z, Chen J, Zhao Y, Zhao Y, Huang H, Zheng SL, Trent JM, Yu L, Jiang D, Mo Z, Wang H, Mou Y, Jiang T, Mao Y, Xu J, Lu D, 2019
- Shuttling SLC2A4RG is regulated by 14-3-3θ to modulate cell survival via caspase-3 and caspase-6 in human glioma, Yun D, Wang H, Wang Y, Chen Y, Zhao Z, Ma J, Ji Y, Huang Q, Chen J, Chen H, Lu D, 2019
- Intracellular generation of single-strand template increases the knock-in efficiency by combining CRISPR/Cas9 with AAV, Xiao Q, Min T, Ma S, Hu L, Chen H, Lu D, 2018
- New applications of CRISPR/Cas9 system on mutant DNA detection, Jia C, Huai C, Ding J, Hu L, Su B, Chen H, Lu D, 2018
- Establishment of a Gene Detection System for Hotspot Mutations of Hearing Loss, Wang C, Wang S, Chen H, Lu D, 2018
- Structural insights into DNA cleavage activation of CRISPR-Cas9 system, Huai C, Li G, Yao R, Zhang Y, Cao M, Kong L, Jia C, Yuan H, Chen H, Lu D, Huang Q, 2017
- CRISPR/Cas9-mediated somatic and germline gene correction to restore hemostasis in hemophilia B mice, Huai C, Jia C, Sun R, Xu P, Min T, Wang Q, Zheng C, Chen H, Lu D, 2017
- The establishment and application of preimplantation genetic haplotyping in embryo diagnosis for reciprocal and Robertsonian translocation carriers, Zhang S, Lei C, Wu J, Zhou J, Sun H, Fu J, Sun Y, Sun X, Lu D, Zhang Y, 2017
Awards
- National Technological Invention Second Prize (1997): Second Contributor
- National Natural Science Second Prize (2007): Third Contributor
- Provincial and Ministerial Science and Technology First Prize: 5 times
- National Teaching Achievement Second Prize: 1 time
- National Excellent Doctoral Dissertation
- National Excellent Teacher
- China Youth Science and Technology Award
- National Candidate of the National Hundred, Thousand, and Ten Thousand Talent Project
