Professor | Leming Shi | Asia Growth Partners

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Name	Leming Shi
Contact Information	lemingshi@fudan.edu.cn
Language ability	English, Chinese
Province	Shanghai

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Name

Leming Shi

Contact Information

lemingshi@fudan.edu.cn

Language ability

English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Life Sciences
Academic Background & Achievements	1985 - Bachelor's Degree in Analytical Chemistry: Hunan University 1988 - Master's Degree in Computational Chemistry: University of Science and Technology of China 1991 - Ph.D. in Computational Chemistry: Institute of Process Engineering, Chinese Academy of Sciences Published over 200 papers, including 15 in Nature Biotechnology h-index of 55 with over 13,000 citations Co-authored the book 'Big Data and Precision Medicine' (2017) Co-founded the International MAQC Society and served as its first president (2017-2018)
Work Experience	1991-1993 - Assistant Researcher: Institute of Process Engineering, Chinese Academy of Sciences 1993-1994 - Associate Researcher: Institute of Process Engineering, Chinese Academy of Sciences 1994-1997 - Postdoctoral Researcher: Case Western Reserve University and NIH/NCI 1997-2001 - Various roles: FDA, Wyeth, and BASF in the USA 2001 - Co-founder: Shenzhen Chipscreen Biosciences 2003 - Rejoined FDA: Initiated MAQC/SEQC 2011 - Joined Fudan University: Professor at School of Life Sciences, Human Phenome Institute, and affiliated Cancer Hospital
Awards	2017 - Chinese Patent Gold Award (4th contributor) 2019 - Chief Scientist of National Key R&D Program 'Strategic International Scientific and Technological Innovation Cooperation'

University/Lab Affiliation and Title

Fudan University

Faculty

Life Sciences

Academic Background & Achievements

1985 - Bachelor's Degree in Analytical Chemistry: Hunan University
1988 - Master's Degree in Computational Chemistry: University of Science and Technology of China
1991 - Ph.D. in Computational Chemistry: Institute of Process Engineering, Chinese Academy of Sciences
Published over 200 papers, including 15 in Nature Biotechnology
h-index of 55 with over 13,000 citations
Co-authored the book 'Big Data and Precision Medicine' (2017)
Co-founded the International MAQC Society and served as its first president (2017-2018)

Work Experience

1991-1993 - Assistant Researcher: Institute of Process Engineering, Chinese Academy of Sciences
1993-1994 - Associate Researcher: Institute of Process Engineering, Chinese Academy of Sciences
1994-1997 - Postdoctoral Researcher: Case Western Reserve University and NIH/NCI
1997-2001 - Various roles: FDA, Wyeth, and BASF in the USA
2001 - Co-founder: Shenzhen Chipscreen Biosciences
2003 - Rejoined FDA: Initiated MAQC/SEQC
2011 - Joined Fudan University: Professor at School of Life Sciences, Human Phenome Institute, and affiliated Cancer Hospital

Awards

2017 - Chinese Patent Gold Award (4th contributor)
2019 - Chief Scientist of National Key R&D Program 'Strategic International Scientific and Technological Innovation Cooperation'

Areas of Focus	Chemical Genomics Pharmacogenomics Precision Medicine Medical Big Data Bioinformatics Cheminformatics
Publications	Towards best practice in cancer mutation detection with whole-genome and whole-exome sequencing, Xiao W, Ren L, ..., Wang C, Shi L, 2021 Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing, Fang LT, Zhu B, Zhao Y, ..., Hong H, Shi L, Wang C, Xiao W, 2021 Genomic and transcriptomic landscape of triple-negative breast cancers: subtypes and treatment strategies, Jiang YZ, Ma D, Suo C, Shi J, Xue M, Hu X, ..., Wang P, Shi L, Huang W, Shao ZM, 2019 The international MAQC Society launches to enhance reproducibility of high-throughput technologies, Shi L, ..., Tong W, 2017 Telomerase activation by genomic rearrangements in high-risk neuroblastoma, Peifer M, Hertwig F, Roels F, Dreidax D, Gartlgruber M, ..., Shi L, ..., Westermann F, Thomas RK, Fischer M, 2015 A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequence Quality Control consortium, Su Z, Łabaj PP, Li S, ..., Kreil DP, Mason CE, Shi L, 2014 The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models, Shi L, ..., Wolfinger RD, 2010 Evaluation of external RNA controls for the assessment of microarray performance, Tong W, ..., Shi L, 2006 Rat toxicogenomic study reveals analytical consistency across microarray platforms, Guo L, ..., Shi L, 2006 The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements, Shi L, ..., Slikker W, Jr, 2006

Areas of Focus

Chemical Genomics
Pharmacogenomics
Precision Medicine
Medical Big Data
Bioinformatics
Cheminformatics

Publications

Towards best practice in cancer mutation detection with whole-genome and whole-exome sequencing, Xiao W, Ren L, ..., Wang C, Shi L, 2021
Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing, Fang LT, Zhu B, Zhao Y, ..., Hong H, Shi L, Wang C, Xiao W, 2021
Genomic and transcriptomic landscape of triple-negative breast cancers: subtypes and treatment strategies, Jiang YZ, Ma D, Suo C, Shi J, Xue M, Hu X, ..., Wang P, Shi L, Huang W, Shao ZM, 2019
The international MAQC Society launches to enhance reproducibility of high-throughput technologies, Shi L, ..., Tong W, 2017
Telomerase activation by genomic rearrangements in high-risk neuroblastoma, Peifer M, Hertwig F, Roels F, Dreidax D, Gartlgruber M, ..., Shi L, ..., Westermann F, Thomas RK, Fischer M, 2015
A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequence Quality Control consortium, Su Z, Łabaj PP, Li S, ..., Kreil DP, Mason CE, Shi L, 2014
The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models, Shi L, ..., Wolfinger RD, 2010
Evaluation of external RNA controls for the assessment of microarray performance, Tong W, ..., Shi L, 2006
Rat toxicogenomic study reveals analytical consistency across microarray platforms, Guo L, ..., Shi L, 2006
The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements, Shi L, ..., Slikker W, Jr, 2006

Chemical Genomics Pharmacogenomics Precision Medicine Medical Big Data Bioinformatics Cheminformatics Biomarkers Disease Prevention Diagnosis Treatment

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