Professor | Jiucun Wang | Asia Growth Partners

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Name	Jiucun Wang
Contact Information	jcwang@fudan.edu.cn
Language ability	English, Chinese, Japanese
Province	Shanghai

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Name

Jiucun Wang

Contact Information

jcwang@fudan.edu.cn

Language ability

English, Chinese, Japanese

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Life Sciences
Academic Background & Achievements	1988-1991: Bachelor's and Master's degrees in Biology from Fudan University 1999: Ph.D. in Applied Biological Chemistry from Fukui University, Japan 2007-2008: Visiting Researcher at the University of Texas Health Science Center at Houston
Work Experience	1991-1994: Assistant Lecturer and Lecturer at the School of Life Sciences, Fudan University 2000-present: Lecturer, Associate Professor, and Professor at the School of Life Sciences, Fudan University Current: Director of the Department of Anthropology and Human Genetics, School of Life Sciences, Fudan University Current: Co-Director of the Joint Laboratory of Skin Phenome Current: Co-Director of the Innovation Research Unit of CAMS Current: Adjunct Professor at Huashan Hospital, Fudan University
Awards	2023: First Prize, Liu Zudong Human Genetics Award, Fudan University 2022: First Prize, Ministry of Education Science and Technology Progress Award (Second Contributor) 2021: Shanghai Education System Women's Civilization Post 2019-2020: Fudan University March 8th Red Flag Collective 2019: Top Ten Scientific Advances, Center for Genetic and Developmental Coordination Innovation 2012: First Elite Award, Fudan University Rheumatology and Immunology Research Center

University/Lab Affiliation and Title

Fudan University

Faculty

Life Sciences

Academic Background & Achievements

1988-1991: Bachelor's and Master's degrees in Biology from Fudan University
1999: Ph.D. in Applied Biological Chemistry from Fukui University, Japan
2007-2008: Visiting Researcher at the University of Texas Health Science Center at Houston

Work Experience

1991-1994: Assistant Lecturer and Lecturer at the School of Life Sciences, Fudan University
2000-present: Lecturer, Associate Professor, and Professor at the School of Life Sciences, Fudan University
Current: Director of the Department of Anthropology and Human Genetics, School of Life Sciences, Fudan University
Current: Co-Director of the Joint Laboratory of Skin Phenome
Current: Co-Director of the Innovation Research Unit of CAMS
Current: Adjunct Professor at Huashan Hospital, Fudan University

Awards

2023: First Prize, Liu Zudong Human Genetics Award, Fudan University
2022: First Prize, Ministry of Education Science and Technology Progress Award (Second Contributor)
2021: Shanghai Education System Women's Civilization Post
2019-2020: Fudan University March 8th Red Flag Collective
2019: Top Ten Scientific Advances, Center for Genetic and Developmental Coordination Innovation
2012: First Elite Award, Fudan University Rheumatology and Immunology Research Center

Areas of Focus	Genetics and molecular mechanisms of systemic sclerosis and ankylosing spondylitis Skin phenomics and human high-altitude adaptation phenomics
Publications	Enhancement of zyxin promotes skin fibrosis by regulating FAK/PI3K/AKT and TGF-β signaling pathways via integrins, Huang Y, Zhao H, Zhang Y, Tang Y, Shi X, Jiang S, Pu W, Liu J, Ma Y, Lin J, Lin J, Wu W, Gong Y, Wang J, Liu Q, 2023 Quantitative assessment of ultraviolet-induced erythema and tanning responses in the Han Chinese population, Ma Y, Tan Yimei, Hu Y, Pu W, Xu J, Jin L, Wang J, 2023 The composite phenotype analysis identifies potential concerted responses of physiological systems to high altitude exposure, Yi Li, Meng Hao, Zixin Hu, Yanyun Ma, Kun Wang, Xiaoyu Liu, Longli Kang, Wenyuan Duan, Bin Qiao, Wang J, Li Jin, 2023 CTHRC1+ fibroblasts are stimulated by macrophage-secreted SPP1 to induce excessive collagen deposition in keloids, Liu J, Huang Y, Gong Y, Liu Q, Lin J, Liu J, Liu M, Huang J, Pu W, Ma Y, Zhang Y, Li H, Shi X, Zhang Y, Wang J, Zhu Y, Wang Q, Wei K, Wang J, Sha Y, Wang J, Wu W, 2022 LDLR dysfunction induces LDL accumulation and promotes pulmonary fibrosis, Shi X, Chen Y, Liu Q, Mei X, Liu J, Zou H, Zhao S, Distler JHW, Jin L, Wang J, 2022 Genetic associations of non-major histocompatibility complex susceptibility loci with systemic sclerosis in a Han Chinese population, Pu W, Zhang R, Ma Y, Liu Q, Jiang S, Liu J, Zhao Y, Tu W, Guo G, Zuo X, Wang Q, Chen Y, Wu W, Zhou X, Distler JHW, Reveille JD, Zou H, Jin L, Mayes MD, Wang J, 2022 Exome-wide association analysis suggests LRP2BP as a susceptibility gene for endothelial injury in systemic sclerosis in Han Chinese population, Pu W, Wu W, Liu Q, Ma Y, Tu W, Zuo X, Guo G, Jiang S, Zhao Y, Zuo X, Wang Q, Yang L, Xiao R, Qi Q, Bai P, Zhao L, Reveille JD, Mayes MD, Jin L, Lee EB, Zhang X, Xu J, Zhang Z, Zhou X, Zou H, Wang J, 2021 Single-cell RNA sequencing deciphers innate immunity in pathogenesis and treatment response of ankylosing spondylitis, Liu J, Tang Y, Huang Y, Gao J, Jiang S, Liu Q, Ma Y, Qian X, Qian F, Reveille JD, He D, Zou H, Jin L, Zhu Q, Pu W, Wang J, 2021 Characterization of the human skin resistome and identification of two microbiota cutotypes, Li Z, Xia J, Jiang L, Tan Y, An Y, Zhu X, Ruan J, Chen Z, Zhen H, Ma Y, Jie Z, Xiao L, Yang H, Wang J, Kristiansen K, Xu X, Jin L, Nie C, Krutmann J, Liu X, Wang J, 2021 A mitochondrial DNA variant elevates the risk of gallstone disease by altering mitochondrial function, Sun D, Niu Z, Zheng H, Wu F, Jiang L, Han TQ, Wei Y, Wang J, Jin L, 2020 Genetic association of non-MHC region with ankylosing spondylitis in a Chinese population, Liu J, Pu W, Li Y, Ma Y, Zhu Q, Wan W, Yang C, Wang X, Chen X, Zhou X, Reveille JD, Jin L, Zou H, Wang J, 2019 A gene-based recessive diplotype exome scan discovers FGF6, a novel hepcidin-regulating iron metabolism gene, Guo S, Jiang S, Epperla N, Ma Y, Maadooliat M, Ye Z, Olson B, Wang M, Kitchner T, Joyce J, An P, Wang F, Strenn R, Mazza JJ, Meece JK, Wu W, Jin L, Smith JA, Wang J, Schrodi SJ, 2019 Evaluation of the antifibrotic potency by knocking down SPARC, CCR2 and SMAD3, Ding W, Pu W, Jiang S, Ma Y, Liu Q, Wu W, Chu H, Zou H, Jin L, Wang J, Zhou X, 2018 Genome-wide DNA methylation analysis in systemic sclerosis reveals hypomethylation of interferon-associated genes in CD4+ and CD8+ T cells, Ding W, Pu W, Wang L, Jiang S, Zhou X, Tu W, Yu L, Zhang J, Guo S, Liu Q, Ma Y, Chen S, Wu W, Reveille J, Zou H, Jin L, Wang J, 2018 Sirtuin1 protects against systemic sclerosis-related pulmonary fibrosis by decreasing proinflammatory and profibrotic processes, Chu H, Jiang S, Liu Q, Ma Y, Zhu X, Liang M, Shi X, Ding W, Zhou X, Zou H, Qian F, Shaul PW, Jin L, Wang J, 2018 Copy number variants of ABCF1, IL17REL, and FCGR3A are associated with the risk of gout, Dong Z, Li Y, Zhou J, Jiang S, Wang Y, Chen Y, Zhao D, Yang C, Qian Q, Ma Y, He H, Ji H, Yang Y, Wang X, Xu X, Pang Y, Zou H, Jin L, Zhang F, Wang J, 2017

Areas of Focus

Genetics and molecular mechanisms of systemic sclerosis and ankylosing spondylitis
Skin phenomics and human high-altitude adaptation phenomics

Publications

Enhancement of zyxin promotes skin fibrosis by regulating FAK/PI3K/AKT and TGF-β signaling pathways via integrins, Huang Y, Zhao H, Zhang Y, Tang Y, Shi X, Jiang S, Pu W, Liu J, Ma Y, Lin J, Lin J, Wu W, Gong Y, Wang J, Liu Q, 2023
Quantitative assessment of ultraviolet-induced erythema and tanning responses in the Han Chinese population, Ma Y, Tan Yimei, Hu Y, Pu W, Xu J, Jin L, Wang J, 2023
The composite phenotype analysis identifies potential concerted responses of physiological systems to high altitude exposure, Yi Li, Meng Hao, Zixin Hu, Yanyun Ma, Kun Wang, Xiaoyu Liu, Longli Kang, Wenyuan Duan, Bin Qiao, Wang J, Li Jin, 2023
CTHRC1+ fibroblasts are stimulated by macrophage-secreted SPP1 to induce excessive collagen deposition in keloids, Liu J, Huang Y, Gong Y, Liu Q, Lin J, Liu J, Liu M, Huang J, Pu W, Ma Y, Zhang Y, Li H, Shi X, Zhang Y, Wang J, Zhu Y, Wang Q, Wei K, Wang J, Sha Y, Wang J, Wu W, 2022
LDLR dysfunction induces LDL accumulation and promotes pulmonary fibrosis, Shi X, Chen Y, Liu Q, Mei X, Liu J, Zou H, Zhao S, Distler JHW, Jin L, Wang J, 2022
Genetic associations of non-major histocompatibility complex susceptibility loci with systemic sclerosis in a Han Chinese population, Pu W, Zhang R, Ma Y, Liu Q, Jiang S, Liu J, Zhao Y, Tu W, Guo G, Zuo X, Wang Q, Chen Y, Wu W, Zhou X, Distler JHW, Reveille JD, Zou H, Jin L, Mayes MD, Wang J, 2022
Exome-wide association analysis suggests LRP2BP as a susceptibility gene for endothelial injury in systemic sclerosis in Han Chinese population, Pu W, Wu W, Liu Q, Ma Y, Tu W, Zuo X, Guo G, Jiang S, Zhao Y, Zuo X, Wang Q, Yang L, Xiao R, Qi Q, Bai P, Zhao L, Reveille JD, Mayes MD, Jin L, Lee EB, Zhang X, Xu J, Zhang Z, Zhou X, Zou H, Wang J, 2021
Single-cell RNA sequencing deciphers innate immunity in pathogenesis and treatment response of ankylosing spondylitis, Liu J, Tang Y, Huang Y, Gao J, Jiang S, Liu Q, Ma Y, Qian X, Qian F, Reveille JD, He D, Zou H, Jin L, Zhu Q, Pu W, Wang J, 2021
Characterization of the human skin resistome and identification of two microbiota cutotypes, Li Z, Xia J, Jiang L, Tan Y, An Y, Zhu X, Ruan J, Chen Z, Zhen H, Ma Y, Jie Z, Xiao L, Yang H, Wang J, Kristiansen K, Xu X, Jin L, Nie C, Krutmann J, Liu X, Wang J, 2021
A mitochondrial DNA variant elevates the risk of gallstone disease by altering mitochondrial function, Sun D, Niu Z, Zheng H, Wu F, Jiang L, Han TQ, Wei Y, Wang J, Jin L, 2020
Genetic association of non-MHC region with ankylosing spondylitis in a Chinese population, Liu J, Pu W, Li Y, Ma Y, Zhu Q, Wan W, Yang C, Wang X, Chen X, Zhou X, Reveille JD, Jin L, Zou H, Wang J, 2019
A gene-based recessive diplotype exome scan discovers FGF6, a novel hepcidin-regulating iron metabolism gene, Guo S, Jiang S, Epperla N, Ma Y, Maadooliat M, Ye Z, Olson B, Wang M, Kitchner T, Joyce J, An P, Wang F, Strenn R, Mazza JJ, Meece JK, Wu W, Jin L, Smith JA, Wang J, Schrodi SJ, 2019
Evaluation of the antifibrotic potency by knocking down SPARC, CCR2 and SMAD3, Ding W, Pu W, Jiang S, Ma Y, Liu Q, Wu W, Chu H, Zou H, Jin L, Wang J, Zhou X, 2018
Genome-wide DNA methylation analysis in systemic sclerosis reveals hypomethylation of interferon-associated genes in CD4+ and CD8+ T cells, Ding W, Pu W, Wang L, Jiang S, Zhou X, Tu W, Yu L, Zhang J, Guo S, Liu Q, Ma Y, Chen S, Wu W, Reveille J, Zou H, Jin L, Wang J, 2018
Sirtuin1 protects against systemic sclerosis-related pulmonary fibrosis by decreasing proinflammatory and profibrotic processes, Chu H, Jiang S, Liu Q, Ma Y, Zhu X, Liang M, Shi X, Ding W, Zhou X, Zou H, Qian F, Shaul PW, Jin L, Wang J, 2018
Copy number variants of ABCF1, IL17REL, and FCGR3A are associated with the risk of gout, Dong Z, Li Y, Zhou J, Jiang S, Wang Y, Chen Y, Zhao D, Yang C, Qian Q, Ma Y, He H, Ji H, Yang Y, Wang X, Xu X, Pang Y, Zou H, Jin L, Zhang F, Wang J, 2017

Genetics Molecular Mechanisms Systemic Sclerosis Ankylosing Spondylitis Skin Phenomics High-Altitude Adaptation Fibrosis Microbiome Hla Region Innate Immunity

Xuehui Huang - Shanghai Normal University

Fang Yu - Shanghai Normal University

Na Wang - Shanghai Normal University

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