Professor | Gang Wang | Asia Growth Partners

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Name	Gang Wang
Contact Information	gwang_fd@fudan.edu.cn
Language ability	English, Chinese
Province	Shanghai

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Name

Gang Wang

Contact Information

gwang_fd@fudan.edu.cn

Language ability

English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Life Sciences
Academic Background & Achievements	1988 - B.S. in Psychology: Peking University 1993 - M.S. in Psychology: University of North Carolina 1998 - Ph.D. in Molecular and Cellular Biology: Tulane University Published papers in prominent journals such as Mol Cell, Dev Cell, Genes Dev, EMBO J, PNAS, Nature Comm, PloS Biol
Work Experience	1999-2005 - University of California, Los Angeles - Postdoctoral fellow and Assistant Researcher 2006-2019 - Institute of Biochemistry and Cell Biology, Chinese Academy of Science - Researcher 2019-Present - Fudan University School of Life Sciences - Distinguished Professor and Vice Dean
Awards	Chinese Academy of Science 'Hundred Talent Program' Pujiang Talent Program State Council Special Allowance Zhu Li Yuehua Outstanding Teacher Award (2013) Outstanding Graduate Advisor Award (2013)

University/Lab Affiliation and Title

Fudan University

Faculty

Life Sciences

Academic Background & Achievements

1988 - B.S. in Psychology: Peking University
1993 - M.S. in Psychology: University of North Carolina
1998 - Ph.D. in Molecular and Cellular Biology: Tulane University
Published papers in prominent journals such as Mol Cell, Dev Cell, Genes Dev, EMBO J, PNAS, Nature Comm, PloS Biol

Work Experience

1999-2005 - University of California, Los Angeles - Postdoctoral fellow and Assistant Researcher
2006-2019 - Institute of Biochemistry and Cell Biology, Chinese Academy of Science - Researcher
2019-Present - Fudan University School of Life Sciences - Distinguished Professor and Vice Dean

Awards

Chinese Academy of Science 'Hundred Talent Program'
Pujiang Talent Program
State Council Special Allowance
Zhu Li Yuehua Outstanding Teacher Award (2013)
Outstanding Graduate Advisor Award (2013)

Areas of Focus	Epigenetic transcription regulation Molecular mechanisms of development Mediator co-factor complex Gene expression regulation Developmental and physiological settings Dysregulated Mediator in diseases Non-canonical roles of Mediator Transcription elongation mRNA processing Chromatin changes
Publications	Med23 deficiency reprograms the tumor microenvironment to promote lung tumorigenesis, Xiaobo Fu, Siming Liu, Dan Cao, Chonghui Li, Hongbin Ji, Gang Wang, 2023 An intellectual disability-related MED23 mutation dysregulates gene expression by altering chromatin conformation and enhancer activities, Yenan Yang, Chonghui Li, Ziying Chen, Yiyang Zhang, Qing Tian, Meiling Sun, Shuai Zhang, Miao Yu, Gang Wang, 2023 Med23 supports angiogenesis and maintains vascular integrity through negative regulation of angiopoietin2 expression, Yenan Yang, Qi Xiao, Jingwen Yin, Chonghui Li, Decai Yu, Yulong He, Zhongzhou Yang, Gang Wang, 2022 Insulin signaling establishes a developmental trajectory of adipose Treg cells, Yangyang Li, Ying Lu, Shuhai Lin, Ning Li, Yichao Han, Qianru Huang, Yi Zhao, Feng Xie, Yixian Guo, Biaolong Deng, Andy Tsuna, Juan Du, Dan Li, Joanne Sun, Guochao Shi, Fang Zheng, Xiao Su, Shengzhong Duan, Song Guo Zheng, Gang Wang, Xuemei Tong, Bin Li, 2021 Mediator Med23 deficiency in smooth muscle cells prevents neointima formation after arterial injury, Xiaoli Sun, Jing-wen Yin, Yan Liang, Chonghui Li, Pingjin Gao, Ying Yu, Gang Wang, 2021 Phosphorylation of Msx1 promotes cell proliferation through the Fgf9/18-MAPK signaling pathway during embryonic limb development, Yenan Yang, Xiaoli Zhu, Xiang Jia, Wanwan Hou, Guoqiang Zhou, Zhangjing Ma, Bin Yu, Yan Pi, Xumin Zhang, Jingqiang Wang, Gang Wang, 2020 Mediator MED23 regulates inflammatory responses and liver fibrosis, Zhichao Wang, Dan Cao, Chonghui Li, Lihua Min, Gang Wang, 2019 Mediator subunit MED23 links pigmentation and DNA repair through the transcription factor MITF, Min Xia, Kun Chen, Xiao Yao, Yichi Xu, Jiaying Yao, Jun Yan, Zhen Shao, Gang Wang, 2017 Mediator MED23 cooperates with RUNX2 to drive osteoblast differentiation and bone development, Zhen Liu, Xiao Yao, Guang Yan, Yichi Xu, Jun Yan, Weiguo Zou, Gang Wang, 2016 The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination, Xiao Yao, Zhanyun Tang, Jingwen Yin, Yan Liang, Xing Fu, Robert G. Roeder, Gang Wang, 2015 Mediator Med23-deficiency Enhances Neural Differentiation of Embryonic Stem Cells through Modulating BMP Signaling, Wanqu Zhu, Xiao Yao, Yan Liang, Dan Liang, Lu Song, Naihe Jing, Jinsong Li, Gang Wang, 2015 The mediator subunit Med23 contributes to controlling T-cell activation and prevents autoimmunity, Yang Sun, Xiaoyan Zhu, Xufeng Chen, Haifeng Liu, Yu Xu, Yajing Chu, Gang Wang, Xiaolong Liu, 2014 The Mediator complex: a master coordinator of transcription and cell lineage development, Jingwen Yin, Gang Wang, 2014 Liver Med23 ablation improves glucose and lipid metabolism through modulating FOXO1 activity, Yajing Chu, Leonardo Gomez Rosso, Ping Huang, Zhichao Wang, Yichi Xu, Xiao Yao, Menghan Bao, Jun Yan, Haiyun Song, Gang Wang, 2014 Stimulation of somatic cell reprogramming by ERas-Akt-FoxO1 signaling axis, Yong Yu, Dan Liang, Qing Tian, Xiaona Chen, Bo Jiang, Binkuan Chou, Ping Hu, Linzhao Cheng, Ping Gao, Jinsong Li, Gang Wang, 2014 Mediator MED15 modulates transforming growth factor beta (TGFβ)/Smad signaling and breast cancer cell metastasis, Meng Zhao, Xu Yang, Yu Fu, Haifang Wang, Yuanheng Ning, Jun Yan, Ye-Guang Chen, Gang Wang, 2013 The Mediator MED23 plays opposing roles in directing smooth muscle cell and adipocyte differentiation, Jingwen Yin, Yan Liang, JiYeon Park, Dongrui Chen, Xiao Yao, Qi Xiao, Zhen Liu, Bo Jiang, Yu Fu, Menghan Bao, Yan Huang, Yuting Liu, Jun Yan, Minsheng Zhu, Zhongzhou Yang, Pingjin Gao, Bin Tian, Dangsheng Li, Gang Wang, 2012 Selective Requirement for Mediator MED23 in Ras-active Lung Cancer, Xu Yang, Meng Zhao, Min Xia, Yuting Liu, Jun Yan, Hongbin Ji, Gang Wang, 2012 Mediator Complex Regulates Alternative mRNA Processing via the MED23 Subunit, Yan Huang, Wencheng Li, Xiao Yao, Qijiang Lin, Jingwen Yin, Yan Liang, Monika Heiner, Bin Tian, Jingyi Hui, Gang Wang, 2012 Mediator MED23 links insulin signaling to the adipogenesis transcription cascade, Wei Wang, Lu Huang, Yan Huang, Jingwen Yin, Arnold J. Berk, Jeffrey Friedman, Gang Wang, 2009

Areas of Focus

Epigenetic transcription regulation
Molecular mechanisms of development
Mediator co-factor complex
Gene expression regulation
Developmental and physiological settings
Dysregulated Mediator in diseases
Non-canonical roles of Mediator
Transcription elongation
mRNA processing
Chromatin changes

Publications

Med23 deficiency reprograms the tumor microenvironment to promote lung tumorigenesis, Xiaobo Fu, Siming Liu, Dan Cao, Chonghui Li, Hongbin Ji, Gang Wang, 2023
An intellectual disability-related MED23 mutation dysregulates gene expression by altering chromatin conformation and enhancer activities, Yenan Yang, Chonghui Li, Ziying Chen, Yiyang Zhang, Qing Tian, Meiling Sun, Shuai Zhang, Miao Yu, Gang Wang, 2023
Med23 supports angiogenesis and maintains vascular integrity through negative regulation of angiopoietin2 expression, Yenan Yang, Qi Xiao, Jingwen Yin, Chonghui Li, Decai Yu, Yulong He, Zhongzhou Yang, Gang Wang, 2022
Insulin signaling establishes a developmental trajectory of adipose Treg cells, Yangyang Li, Ying Lu, Shuhai Lin, Ning Li, Yichao Han, Qianru Huang, Yi Zhao, Feng Xie, Yixian Guo, Biaolong Deng, Andy Tsuna, Juan Du, Dan Li, Joanne Sun, Guochao Shi, Fang Zheng, Xiao Su, Shengzhong Duan, Song Guo Zheng, Gang Wang, Xuemei Tong, Bin Li, 2021
Mediator Med23 deficiency in smooth muscle cells prevents neointima formation after arterial injury, Xiaoli Sun, Jing-wen Yin, Yan Liang, Chonghui Li, Pingjin Gao, Ying Yu, Gang Wang, 2021
Phosphorylation of Msx1 promotes cell proliferation through the Fgf9/18-MAPK signaling pathway during embryonic limb development, Yenan Yang, Xiaoli Zhu, Xiang Jia, Wanwan Hou, Guoqiang Zhou, Zhangjing Ma, Bin Yu, Yan Pi, Xumin Zhang, Jingqiang Wang, Gang Wang, 2020
Mediator MED23 regulates inflammatory responses and liver fibrosis, Zhichao Wang, Dan Cao, Chonghui Li, Lihua Min, Gang Wang, 2019
Mediator subunit MED23 links pigmentation and DNA repair through the transcription factor MITF, Min Xia, Kun Chen, Xiao Yao, Yichi Xu, Jiaying Yao, Jun Yan, Zhen Shao, Gang Wang, 2017
Mediator MED23 cooperates with RUNX2 to drive osteoblast differentiation and bone development, Zhen Liu, Xiao Yao, Guang Yan, Yichi Xu, Jun Yan, Weiguo Zou, Gang Wang, 2016
The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination, Xiao Yao, Zhanyun Tang, Jingwen Yin, Yan Liang, Xing Fu, Robert G. Roeder, Gang Wang, 2015
Mediator Med23-deficiency Enhances Neural Differentiation of Embryonic Stem Cells through Modulating BMP Signaling, Wanqu Zhu, Xiao Yao, Yan Liang, Dan Liang, Lu Song, Naihe Jing, Jinsong Li, Gang Wang, 2015
The mediator subunit Med23 contributes to controlling T-cell activation and prevents autoimmunity, Yang Sun, Xiaoyan Zhu, Xufeng Chen, Haifeng Liu, Yu Xu, Yajing Chu, Gang Wang, Xiaolong Liu, 2014
The Mediator complex: a master coordinator of transcription and cell lineage development, Jingwen Yin, Gang Wang, 2014
Liver Med23 ablation improves glucose and lipid metabolism through modulating FOXO1 activity, Yajing Chu, Leonardo Gomez Rosso, Ping Huang, Zhichao Wang, Yichi Xu, Xiao Yao, Menghan Bao, Jun Yan, Haiyun Song, Gang Wang, 2014
Stimulation of somatic cell reprogramming by ERas-Akt-FoxO1 signaling axis, Yong Yu, Dan Liang, Qing Tian, Xiaona Chen, Bo Jiang, Binkuan Chou, Ping Hu, Linzhao Cheng, Ping Gao, Jinsong Li, Gang Wang, 2014
Mediator MED15 modulates transforming growth factor beta (TGFβ)/Smad signaling and breast cancer cell metastasis, Meng Zhao, Xu Yang, Yu Fu, Haifang Wang, Yuanheng Ning, Jun Yan, Ye-Guang Chen, Gang Wang, 2013
The Mediator MED23 plays opposing roles in directing smooth muscle cell and adipocyte differentiation, Jingwen Yin, Yan Liang, JiYeon Park, Dongrui Chen, Xiao Yao, Qi Xiao, Zhen Liu, Bo Jiang, Yu Fu, Menghan Bao, Yan Huang, Yuting Liu, Jun Yan, Minsheng Zhu, Zhongzhou Yang, Pingjin Gao, Bin Tian, Dangsheng Li, Gang Wang, 2012
Selective Requirement for Mediator MED23 in Ras-active Lung Cancer, Xu Yang, Meng Zhao, Min Xia, Yuting Liu, Jun Yan, Hongbin Ji, Gang Wang, 2012
Mediator Complex Regulates Alternative mRNA Processing via the MED23 Subunit, Yan Huang, Wencheng Li, Xiao Yao, Qijiang Lin, Jingwen Yin, Yan Liang, Monika Heiner, Bin Tian, Jingyi Hui, Gang Wang, 2012
Mediator MED23 links insulin signaling to the adipogenesis transcription cascade, Wei Wang, Lu Huang, Yan Huang, Jingwen Yin, Arnold J. Berk, Jeffrey Friedman, Gang Wang, 2009

Epigenetics Transcription Mediator Gene Regulation Development Diseases Mrna Chromatin Stem Cells Cancer

Jiang Cizhong - Tongji University

Jiuhong Kang - Tongji University

Changdong Lin - Tongji University

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