2000 - PhD in Bioorganic Chemistry: Hokkaido University
2001-2003 - Postdoctoral Research: Hokkaido University and Gifu University
2004-2006 - JSPS Foreign Researcher: University of Tokyo
2011 - Doctoral Supervisor: Fudan University
2012 - Professor: Fudan University
2001-2003 - Postdoctoral Researcher: Hokkaido University and Gifu University
2004-2006 - JSPS Foreign Researcher: University of Tokyo
2006-Present - Associate Professor and Professor: Fudan University
2017 - Chinese Pharmaceutical Association Science and Technology Award (Third Prize)
2012 - Chinese Pharmaceutical Association Science and Technology Award (Third Prize)
2016 - Shanghai Pharmaceutical Science and Technology Award (First Prize)
2011 - Shanghai Pharmaceutical Science and Technology Award (Third Prize)
2011, 2012 - Fosun Pharma Teaching Award
2017 - Lu Zonglin Teaching Award
2016 - Contribution Award of Chinese Overseas Chinese Community (Innovative Talent)
2016 - Candidate for China's Annual Science News Figure
2020 - China Technology Market Association Golden Bridge Award (Second Prize)
Research
Molecular Mechanisms of Disease and Drug Development Function and Regulation of Drug Transporters in Drug Metabolism
What is the prospect of indoleamine 2,3-dioxygenase 1 inhibition in cancer? Extrapolation from the past., Yu Yao, Heng Liang, Xin Fang, Shengnan Zhang, Zikang Xing, Lei Shi, Chunxiang Kuang, Barbara Seliger, Qing Yang, 2021
43 key gene expressions involved in the effect of indoleamine 2,3-dioxygenase 1 (IDO1) expression on cancer prognosis may be a potential IDO1 inhibitor biomarker., Weirui Li, Leilei Guo, Zikang Xing, Xin Fang, Heng Liang, Shengnan Zhang, Lei Shi, Chunxiang Kuang, Leming Shi, Yuanting Zheng, Yueqing Hu, Qing Yang, 2021
Evaluation and Comparison of the Commonly Used Bioassays of Human Indoleamine 2,3-dioxygenase 1(IDO1) and Tryptophan 2,3- dioxygenase (TDO), Shengnan Zhang, Leilei Guo, Dan Yang, Zikang Xing, Weirui Li, Chunxiang Kuang, Qing Yang, 2020
Amyloid β neurotoxicity is IDO1-Kyn-AhR dependent and blocked by IDO1 inhibitor., Zhenzhen Duan, Shengnan Zhang, Heng Liang, Zikang Xing, Leilei Guo, Lei Shi, Lisha Du, Chunxiang Kuang, Osamu Takikawa, Qing Yang, 2020
Both IDO1 and TDO contribute to the malignancy of gliomas via Kyn-AhR-AQP4 signal pathway., Lisha Du, Zikang Xing, Bangbao Tao, Tianqi Li, Dan Yang, Weirui Li, Yuanting Zheng, Chunxiang Kuang, Qing Yang, 2020
N-benzyl/aryl substituted Tryptanthrin as Dual Inhibitors of Indoleamine 2, 3-Dioxygenase and Tryptophan 2, 3-dioxygenase., Dan Yang, Shengnan Zhang, Xin Fang, Leilei Guo, Nan Hu, Zhanling Guo, Xishuai Li, Shuangshuang Yang, Jin Chao He, Chunxiang Kuang, Qing Yang, 2019
H2S suppresses indoleamine 2, 3-dioxygenase 1 and exhibits immunotherapeutic efficacy in murine hepatocellular carcinoma., Dan Yang, Tianqi Li, Yinlong Li, Shengnan Zhang, Weirui Li, Heng Liang, Zikang Xing, Lisha Du, Jinchao He, Chunxiang Kuang, Qing Yang, 2019
The proatherosclerotic function of indoleamine 2, 3-dioxygenase 1 in the developmental stage of atherosclerosis., Heng Liang, Mantian Chen, Fangfei Qi, Lei Shi, Zhenzhen Duan, Ruoyu Yang, Jinchao He, Bin Lou, Yigang Li, Qing Yang, 2019
Regulating the balance between the kynurenine and serotonin pathways of tryptophan metabolism., Yang Li, Nan Hu, Dan Yang, Gregory Oxenkrug, Qing Yang, 2017
Establishment of a human indoleamine 2, 3-dioxygenase2 (hIDO2) bioassay system and discovery of tryptanthrin derivatives as potent hIDO2 inhibitors., Juanjuan Li, Yang Li, Dan Yang, Nan Hu, Zhanling Guo, Chunxiang Kuang, Qing Yang, 2016
SMS regulates the expression and function of P-gp and MRP2 in Caco-2 cells., Guiying Jin, Yang Li, Yuwen Zhu, Lisha Du, Junkai Yan, Qing Yang, 2016
The IDO inhibitor coptisine ameliorates cognitive impairment in a mouse model of Alzheimer's disease., Yu D, Tao BB, Yang YY, Du LS, Yang SS, He XJ, Zhu YW, Yan JK, Yang Q, 2015
Modulation of intestinal folate absorption by erythropoietin in vitro., Junkai Yan, Guiying Jin, Lisha Du, Qing Yang, 2014
Discovery of Tryptanthrin Derivatives as Potent Inhibitors of Indoleamine 2, 3-Dioxygenase with Therapeutic Activity in LLC tumor-bearing Mice., Yang, Shuangshuang, Li, Xishuai, Hu, Fangfang, Li, Yinlong, Yang, Yunyun, Yan, Junkai, Kuang, Chunxiang, Yang, Qing, 2013
The Effect of Radixin Knockdown on the Expression and Efflux Function of MRP2 in SGC-7901 Cells., Xiao-Jie He, Wei-Rong Wang, Yun Zhang, Qing Yang, 2012
Structure-activity relationship and enzyme kinetic studies on 4-aryl-1H-1, 2, 3-triazoles as indoleamine 2, 3-dioxygenase (IDO) inhibitors., Qiang Huang, Maofa Zheng, Shuangshuang Yang, Chunxiang Kuang, Cunjing Yu, Qing Yang, 2011
The Effect of Sphingomyelin Synthase 2 (SMS2) Deficiency on the Expression of Drug Transporters in Mouse Brain., Yu Zhang, Jibin Dong, Xingang Zhu, Weirong Wang, Qing Yang, 2011
Oren-gedoku-to and its constituents with therapeutic potential of Alzheimer′s disease inhibit indoleamine 2, 3-dioxygenase activity in vitro., CunJing Yu, MaoFa Zheng, ChunXiang Kuang, WeiDa Huang, Qing Yang, 2010
Area of Focus
Peptides | Biochemistry | Pharmaceuticals | Drug Development | Pdt | Cancer Research | Molecular Biology | Chemical Synthesis | Protein Engineering | Therapeutics
Area of Focus
Anticancer | Biomolecular | Drug Development | Protein Design | Synthesis | Molecular Biology | Structural Biology | Cancer Therapy | Pharmaceuticals | Biochemistry
