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Shen Bo
Radiation Medicine
Fudan University
Shanghai
Language: English, Chinese
Nanoparticles
Dna Damage
Radiation
P53
Bystander Effect
Cell Metabolism
Nano-Theranostics
Radiotherapy
Hypoxic Tumors
Multifunctional
Areas of Focus
- Nuclear-targeted multifunctional nanoparticles enhancing DNA radiation damage
- p53-dependent radiation bystander effect and cellular energy metabolism
- Novel multifunctional nano-theranostics combined with radiotherapy for hypoxic tumor treatment
Work Experience
- 2008-2010 - Columbia University Radiation Research Center - Postdoctoral Researcher
Academic Background & Achievements
- 2006 PhD in Radiation Medicine: Jilin University
- 2008 Postdoctoral Research: Columbia University Radiation Research Center
Publications
- Role of the medial preoptic area in electroacupuncture treatment of reproductive dysfunction in ovariectomised rats, Ma, Shulan; Li, Dongju; Jiang, Jianwei; Shen, Bo, 2017
- Photosensitizer Effect of 9-hydroxypheophorbide α on Diode Laser-Irradiated Laryngeal Cancer Cells: Oxidative Stress-Directed Cell Death and Migration Suppression, He, Peijie; Shen, Bo; Chung, Aha; Liang, Zhou, 2016
- Intranuclear biophotonics by smart design of nuclear-targeting photo-/radio-sensitizers co-loaded upconversion nanoparticles, Fan Wenpei; Shen, Bo; Bu, Wenbo; Zheng, Xiangpeng; He, Qianjun; Cui, Zhaowen; Ni, Dalong; Zhao, Kuaile; Zhang Shengjian; Shi, Jianlin, 2015
- Targeting Cellular Metabolism Chemosensitizes the Doxorubicin-Resistant Human Breast Adenocarcinoma Cells, Ma, Shu-Lan; Jia, Rong-Fei; Li, Dong-Ju; Shen, Bo, 2015
- Topotecan-loaded mesoporous silica nanoparticles for reversing multi-drug resistance by synergetic chemoradiotherapy, Shen, Bo; Zhao, Kuaile; Ma, Shulan; Yuan, Dexiao; Bai, Yang, 2015
- A smart upconversion-based mesoporous silica nanotheranostic system for synergetic chemo-/radio-/photodynamic therapy and simultaneous MR/UCL imaging, Fan, Wenpei; Shen Bo; Bu, Wenbo; Chen, Feng; He, Qianjun; Zhao, Kuaile; Zhang, Shengjian; Zhou, Liangping; Peng, Weijun; Xiao, Qingfeng; Ni, Dalong; Liu, Jianan; Shi, Jianlin, 2014
- 9-Hydroxypheophorbide alpha-mediated photodynamic therapy induces matrix metalloproteinase-2 (MMP-2) and MMP-9 down-regulation in Hep-2 cells via ROS-mediated suppression of the ERK pathway, Zhang Huankang; Shen Bo; Swinarska, Joanna T.; Li Wen; Xiao Kuanlin; He Peijie, 2014
- Dexamethasone potentiates myeloid-derived suppressor cell function in prolonging allograft survival through nitric oxide, Liao, Jiongbo; Wang, Xiao; Bi, Yujing; Shen, Bo; Shao, Kun; Yang, Hui; Lu, Yun; Zhang, Zhengguo; Chen, Xi; Liu, Huanrong; Wang, Jian; Chu, Yiwei; Xue, Lixiang; Wang, Xianghui; Liu, Guangwei, 2014
- SIRT1 Limits the Function and Fate of Myeloid-Derived Suppressor Cells in Tumors by Orchestrating HIF-1 alpha-Dependent Glycolysis, Liu, Guangwei; Bi, Yujing; Shen, Bo; Yang, Hui; Zhang, Yan; Wang, Xiao; Liu, Huanrong; Lu, Yun; Liao, Jiongbo; Chen, Xi; Chu, Yiwei, 2014
- Norcantharidin Induced DU145 Cell Apoptosis through ROS-Mediated Mitochondrial Dysfunction and Energy Depletion, Shen, Bo; He, Pei-Jie; Shao, Chun-Lin, 2013
- Rattle-Structured Multifunctional Nanotheranostics for Synergetic Chemo-/Radiotherapy and Simultaneous Magnetic/Luminescent Dual-Mode Imaging, Fan, Wenpei; Shen, Bo; Bu, Wenbo; Chen, Feng; Zhao, Kuaile; Zhang, Shengjian; Zhou, Liangping; Peng, Weijun; Xiao, Qingfeng; Xing, Huaiyong; Liu, Jianan; Ni, Dalong; He, Qianjun; Shi, Jianlin, 2013
- Alpha particle-induced bystander effect is mediated by ROS via a p53-dependent SCO2 pathway in hepatoma cells, Li, Jitao; He, Mingyuan; Shen, Bo; Yuan, Dexiao; Shao, Chunlin, 2013
- Kinase AKT1 negatively controls neutrophil recruitment and function in mice, Liu, Guangwei; Bi, Yujing; Wang, Ruoning; Shen, Bo; Zhang, Yan; Yang, Hui; Wang, Xiao; Liu, Huanrong; Lu, Yun; Han, Fei, 2013
- Radiation-induced intercellular signaling mediated by cytochrome-c via a p53-dependent pathway in hepatoma cells, He, Mingyuan; Zhao, Meijia; Shen, Bo; Prise, K. M.; Shao, Chunlin, 2011
