Professor | Bin Ma | Asia Growth Partners

Name	Bin Ma
Contact Information	binma@sjtu.edu.cn
Language ability	English, Chinese
Province	Shanghai

Name

Bin Ma

Contact Information

binma@sjtu.edu.cn

Language ability

English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	Shanghai Jiao Tong University
Faculty	Biomedical Engineering
Academic Background & Achievements	2007/10 to 2012/09, PhD in Cell and Molecular Biology, University of Twente 2005/09 to 2007/07, Master in Medical Pharmaceutical Sciences, University of Groningen (cum laude) 2001/09 to 2005/06, Bachelor in Biological Sciences, Lanzhou University 2011: National Scholarship for Outstanding Self-financed Students Abroad
Work Experience	2015/10 to present, Shanghai Jiao Tong University, School of Biomedical Engineering, Associate Researcher 2014/02 to 2015/06, University Hospital Zurich, Postdoctoral Researcher 2013/01 to 2014/08, University of Zurich, Postdoctoral Researcher
Awards	2016: Shanghai Universities Young Eastern Scholar

University/Lab Affiliation and Title

Shanghai Jiao Tong University

Faculty

Biomedical Engineering

Academic Background & Achievements

2007/10 to 2012/09, PhD in Cell and Molecular Biology, University of Twente
2005/09 to 2007/07, Master in Medical Pharmaceutical Sciences, University of Groningen (cum laude)
2001/09 to 2005/06, Bachelor in Biological Sciences, Lanzhou University
2011: National Scholarship for Outstanding Self-financed Students Abroad

Work Experience

2015/10 to present, Shanghai Jiao Tong University, School of Biomedical Engineering, Associate Researcher
2014/02 to 2015/06, University Hospital Zurich, Postdoctoral Researcher
2013/01 to 2014/08, University of Zurich, Postdoctoral Researcher

Awards

2016: Shanghai Universities Young Eastern Scholar

Areas of Focus	Carcinogenic pathways and tumor microenvironment Tumor endogenous immune escape mechanisms Cancer immunotherapy
Publications	Comparative evaluation of antitumor effects of TNF superfamily costimulatory ligands delivered by mesenchymal stem cells, Gui L, Wang Z, Lou W, Yekehfallah V, Basiri M, Gao WQ, Wang Y, Ma B, 2024 Generation and functional characterization of PLAP CAR-T cells against cervical cancer cells, Yekehfallah V, Pahlavanneshan S, Sayadmanesh A, Momtahan Z, Ma B, Basiri M, 2022 CD24 is a superior immunotherapeutic target to PD-1 in a mouse model of Helicobacter-induced gastric cancer, Ji L, Peng P, Gui L, Yuan P, Qian W, Wang Y, Gao WQ, Ma B, 2022 CCL28 downregulation attenuates pancreatic cancer progression through tumor cell-intrinsic and -extrinsic mechanisms, Yan J, Yuan P, Gui L, Wang Z, Yin P, Gao WQ, Ma B, 2021 β-Catenin inhibition shapes tumor immunity and synergizes with immunotherapy in colorectal cancer, Wang C, Yan J, Yin P, Gui L, Ji L, Ma B, Gao WQ, 2020 Targeted delivery of CXCL9 and OX40L by mesenchymal stem cells elicits potent antitumor immunity, Yin P, Gui L, Wang C, Yan J, Liu M, Ji L, Wang Y, Ma B, Gao WQ, 2020 Blockade of β-catenin-induced CCL28 suppresses gastric cancer progression via inhibition of Treg cell infiltration, Ji L, Qian W, Gui L, Ji Z, Yin P, Lin GN, Wang Y, Ma B, Gao WQ, 2020 Crosstalk between Wnt/β-catenin and NF-κB signaling during inflammation, Ma B, Hottiger MO, 2016 WNT/β-catenin signaling inhibits CBP-mediated RelA acetylation and expression of a proinflammatory subset of NF-κB target genes, Ma B, Fey M, Hottiger MO, 2015 T cell factor 4 is a pro-catabolic and apoptotic factor in human articular chondrocytes by potentiating nuclear factor κB signaling, Ma B, van Blitterswijk CA, Karperien M, 2013 A Wnt/β-catenin negative feedback loop inhibits interleukin-1-induced matrix metalloproteinase expression in human articular chondrocytes, Ma B, van Blitterswijk CA, Karperien M, 2012 Repression of vascular endothelial growth factor expression by the runt-related transcription factor 1 in acute myeloid leukemia, Ter Elst A, Ma B, Scherpen FJG, de Jonge HJ, Douwes J, Wierenga AT, Schuringa JJ, Kamps WA, de Bont ES, 2011

Areas of Focus

Carcinogenic pathways and tumor microenvironment
Tumor endogenous immune escape mechanisms
Cancer immunotherapy

Publications

Comparative evaluation of antitumor effects of TNF superfamily costimulatory ligands delivered by mesenchymal stem cells, Gui L, Wang Z, Lou W, Yekehfallah V, Basiri M, Gao WQ, Wang Y, Ma B, 2024
Generation and functional characterization of PLAP CAR-T cells against cervical cancer cells, Yekehfallah V, Pahlavanneshan S, Sayadmanesh A, Momtahan Z, Ma B, Basiri M, 2022
CD24 is a superior immunotherapeutic target to PD-1 in a mouse model of Helicobacter-induced gastric cancer, Ji L, Peng P, Gui L, Yuan P, Qian W, Wang Y, Gao WQ, Ma B, 2022
CCL28 downregulation attenuates pancreatic cancer progression through tumor cell-intrinsic and -extrinsic mechanisms, Yan J, Yuan P, Gui L, Wang Z, Yin P, Gao WQ, Ma B, 2021
β-Catenin inhibition shapes tumor immunity and synergizes with immunotherapy in colorectal cancer, Wang C, Yan J, Yin P, Gui L, Ji L, Ma B, Gao WQ, 2020
Targeted delivery of CXCL9 and OX40L by mesenchymal stem cells elicits potent antitumor immunity, Yin P, Gui L, Wang C, Yan J, Liu M, Ji L, Wang Y, Ma B, Gao WQ, 2020
Blockade of β-catenin-induced CCL28 suppresses gastric cancer progression via inhibition of Treg cell infiltration, Ji L, Qian W, Gui L, Ji Z, Yin P, Lin GN, Wang Y, Ma B, Gao WQ, 2020
Crosstalk between Wnt/β-catenin and NF-κB signaling during inflammation, Ma B, Hottiger MO, 2016
WNT/β-catenin signaling inhibits CBP-mediated RelA acetylation and expression of a proinflammatory subset of NF-κB target genes, Ma B, Fey M, Hottiger MO, 2015
T cell factor 4 is a pro-catabolic and apoptotic factor in human articular chondrocytes by potentiating nuclear factor κB signaling, Ma B, van Blitterswijk CA, Karperien M, 2013
A Wnt/β-catenin negative feedback loop inhibits interleukin-1-induced matrix metalloproteinase expression in human articular chondrocytes, Ma B, van Blitterswijk CA, Karperien M, 2012
Repression of vascular endothelial growth factor expression by the runt-related transcription factor 1 in acute myeloid leukemia, Ter Elst A, Ma B, Scherpen FJG, de Jonge HJ, Douwes J, Wierenga AT, Schuringa JJ, Kamps WA, de Bont ES, 2011

Carcinogenesis Tumor Microenvironment Immune Escape Immunotherapy Cancer Treatment Molecular Pathways Cell Signaling Immune Response Therapeutic Strategies Clinical Research

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