Areas of Focus
- Functional mechanisms of tumor-related genes in tumorigenesis
- Mesenchymal stem cell carrier cell immunotherapy
Work Experience
- 2021-present, Shanghai Jiao Tong University, Assistant Researcher
Academic Background & Achievements
- 2015-09 to 2021-09, PhD in Biomedical Engineering, Shanghai Jiao Tong University
- Granted a Chinese invention patent
Publications
- SETD2 deficiency accelerates sphingomyelin accumulation and promotes the development of renal cancer, Rao H, Liu C, Wang A, Ma C, Xu Y, Ye T, Su W, Zhou P, Gao WQ, Li L, Ding X, 2023
- Multilevel Regulation of β-Catenin Activity by SETD2 Suppresses the Transition from Polycystic Kidney Disease to Clear Cell Renal Cell Carcinoma, Rao H, Li X, Liu M, Liu J, Feng W, Tang H, Xu J, Gao WQ, Li L, 2021
- DIRAS2 promotes renal cell carcinoma formation by activating the mitogen-activated protein kinase pathway in the absence of von Hippel-Lindau protein, Rao H, Li X, Liu M, Liu J, Li X, Xu J, Li L, Gao WQ, 2020
- Setd2 deficiency promotes gastric tumorigenesis through inhibiting the SIRT1/FOXO pathway, Feng W, Ma C, Rao H, Zhang W, Liu C, Xu Y, Aji R, Wang Z, Xu J, Gao WQ, Li L, 2023
- SETD2 deficiency promotes renal fibrosis through the TGF-β/Smad signalling pathway in the absence of VHL, Liu C, Ni L, Li X, Rao H, Feng W, Zhu Y, Zhang W, Ma C, Xu Y, Gui L, Wang Z, Aji R, Xu J, Gao WQ, Li L, 2023
- Loss of SETD2 aggravates colorectal cancer progression caused by SMAD4 deletion through the RAS/ERK signalling pathway, Ma C, Liu M, Feng W, Rao H, Zhang W, Liu C, Xu Y, Wang Z, Teng Y, Yang X, Ni L, Xu J, Gao WQ, Lu B, Li L, 2023
- The histone methyltransferase SETD2 modulates oxidative stress to attenuate experimental colitis, Liu M, Rao H, Liu J, Li X, Feng W, Gui L, Tang H, Xu J, Gao WQ, Li L, 2021
- SETD2 epidermal deficiency promotes cutaneous wound healing via activation of AKT/mTOR Signalling, Li X, Liu C, Zhu Y, Rao H, Liu M, Gui L, Feng W, Tang H, Xu J, Gao WQ, Li L, 2021
- Stomach-specific c-Myc overexpression drives gastric adenoma in mice via AKT/mTOR signaling, Liu J, Feng W, Liu M, Rao H, Li X, Teng Y, Yang X, Xu J, Gao W, Li L, 2020