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Chen Peng
Veterinary Medicine
China Agricultural University
Beijing
Language: English, Chinese
Contact
Poxvirus Host Specificity Molecular Mechanisms Antiviral Drugs Vaccines Diagnostic Reagents Vector Vaccines Infectious Diseases Oncolytic Viruses Cancer Therapy
Areas of Focus
  • Molecular mechanisms of poxvirus host specificity
  • Development of antiviral drugs, vaccines, and diagnostic reagents for poxvirus diseases
  • Research on vector vaccines for various infectious diseases using modified vaccinia virus Ankara (MVA)
  • Development of oncolytic viruses targeting human or pet cancers
Work Experience
  • 2016.6-2017.6 - Kansas State University, Postdoctoral Researcher
  • 2017.7-2018.1 - The Rockefeller University, Postdoctoral Researcher
  • 2018.1-2020.12 - National Institutes of Health (NIH), Postdoctoral Researcher
Academic Background & Achievements
  • PhD: Kansas State University, Department of Biology
  • Received National Natural Science Foundation Talent Project
  • Received National Key R&D Program of China during the 14th Five-Year Plan period
Publications
  • Genomic analysis of Asian variants of Lumpy Skin Disease Virus and an evaluation of its cellular tropism in vitro, Xie, S., Cui, L., Liao, Z., Zhu, J., Ren, S., Niu, K., Li, H., Jiang, F., Wu, J., Wang, J., Wu, W., Peng, C., 2024
  • DDX5 inhibits inflammation by modulating m6A levels of TLR2/4 transcripts during bacterial infection, Xu, J., Liu, L., Zhi, F., Song, Y., Zhang, Z., Li, B., Zheng, F., Gao, P., Zhang, S., Zhang, Y., Zhang, Y., Qiu, Y., Jiang, B., Li, Y., Peng, C., Chu, Y., 2024
  • The role of ferroptosis in virus infection, Wang, J., Zhu, J., Ren, S., Zhang, Z., Niu, K., Li, H., Wu, W., Peng, C., 2023
  • Human Fam111A inhibits vaccinia virus replication by degrading viral protein I3 and is antagonized by poxvirus host range factor SPI-1, Zhu, J., Gao, X., Li, Y., Zhang, Z., Xie, S., Ren, S., Li, Y., Li, H., Niu, K., Fu, S., Deng, Y., Li, Y., Moss, B., Wu, W., Peng, C., 2023
  • Establishment of a suspension MDBK cell line in serum-free medium for production of bovine alphaherpesvirus-1, Wang, P., Huang, S., Hao, C., Wang, Z., Wang, Z., Zhao, H., Liu, M., Tian, X., Ge, L., Wu, W., Peng, C., 2021
  • Induction of robust and specific humoral and cellular immune responses by bovine viral diarrhea virus virus-like particles engineered with baculovirus expression system, Wang, Z., Liu, M., Zhao, H., Ma, W., Zhang, Y., Wu, W., Peng, C., 2021
  • Repair of a newly identified host range gene contributes to full replication of modified vaccinia virus Ankara (MVA) in human cells, Peng, C., Moss B., 2019
  • Zinc-finger antiviral protein (ZAP) is a restriction factor for replication of modified vaccinia virus Ankara (MVA) in human cells, Peng, C., Wyatt, LS., Glushakow-Smith SG., Lal-Nag, M., Weisberg, AS., Moss, B., 2020
  • Identification of vaccinia virus inhibitors and cellular functions necessary for efficient viral replication by screening bioactive and FDA-approved drugs, Peng, C., Zhou, Y., Cao, S., Pant, A., Campos Guerrero ML., et al., 2020
  • Myxoma virus M156 is a specific inhibitor of rabbit PKR but contains a loss-of-function mutation in Australian virus isolates, Peng, C., Haller, S., Rahman, M., McFadden, G. and Rothenburg, S., 2016
  • Maladaptation after a virus host switch leads to increased activation of the pro-inflammatory NF-κB pathway, Yu, H., Peng, C., Zhang, C. et al., 2022
  • Orthopoxvirus K3 orthologs show virus- and host-specific inhibition of the antiviral protein kinase PKR, Park, C., Peng, C., Rahman, MJ., Haller, SL., Tazi, L., Brennan, G., Rothenburg, S., 2021
Awards
  • 2021: Outstanding Talent in Agricultural Research by the Ministry of Agriculture and Rural Affairs
  • 2021: Beijing Science and Technology Rising Star
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