Professor | Chen Peng | Asia Growth Partners

Name	Chen Peng
Contact Information	pengchenea@cau.edu.cn
Language ability	English, Chinese
Province	Beijing

Name

Chen Peng

Contact Information

pengchenea@cau.edu.cn

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	China Agricultural University
Faculty	Vetrinary Medicine
Academic Background & Achievements	PhD: Kansas State University, Department of Biology Received National Natural Science Foundation Talent Project Received National Key R&D Program of China during the 14th Five-Year Plan period
Work Experience	2016.6-2017.6 - Kansas State University, Postdoctoral Researcher 2017.7-2018.1 - The Rockefeller University, Postdoctoral Researcher 2018.1-2020.12 - National Institutes of Health (NIH), Postdoctoral Researcher
Awards	2021: Outstanding Talent in Agricultural Research by the Ministry of Agriculture and Rural Affairs 2021: Beijing Science and Technology Rising Star

University/Lab Affiliation and Title

China Agricultural University

Faculty

Vetrinary Medicine

Academic Background & Achievements

PhD: Kansas State University, Department of Biology
Received National Natural Science Foundation Talent Project
Received National Key R&D Program of China during the 14th Five-Year Plan period

Work Experience

2016.6-2017.6 - Kansas State University, Postdoctoral Researcher
2017.7-2018.1 - The Rockefeller University, Postdoctoral Researcher
2018.1-2020.12 - National Institutes of Health (NIH), Postdoctoral Researcher

Awards

2021: Outstanding Talent in Agricultural Research by the Ministry of Agriculture and Rural Affairs
2021: Beijing Science and Technology Rising Star

Areas of Focus	Molecular mechanisms of poxvirus host specificity Development of antiviral drugs, vaccines, and diagnostic reagents for poxvirus diseases Research on vector vaccines for various infectious diseases using modified vaccinia virus Ankara (MVA) Development of oncolytic viruses targeting human or pet cancers
Publications	Genomic analysis of Asian variants of Lumpy Skin Disease Virus and an evaluation of its cellular tropism in vitro, Xie, S., Cui, L., Liao, Z., Zhu, J., Ren, S., Niu, K., Li, H., Jiang, F., Wu, J., Wang, J., Wu, W., Peng, C., 2024 DDX5 inhibits inflammation by modulating m6A levels of TLR2/4 transcripts during bacterial infection, Xu, J., Liu, L., Zhi, F., Song, Y., Zhang, Z., Li, B., Zheng, F., Gao, P., Zhang, S., Zhang, Y., Zhang, Y., Qiu, Y., Jiang, B., Li, Y., Peng, C., Chu, Y., 2024 The role of ferroptosis in virus infection, Wang, J., Zhu, J., Ren, S., Zhang, Z., Niu, K., Li, H., Wu, W., Peng, C., 2023 Human Fam111A inhibits vaccinia virus replication by degrading viral protein I3 and is antagonized by poxvirus host range factor SPI-1, Zhu, J., Gao, X., Li, Y., Zhang, Z., Xie, S., Ren, S., Li, Y., Li, H., Niu, K., Fu, S., Deng, Y., Li, Y., Moss, B., Wu, W., Peng, C., 2023 Establishment of a suspension MDBK cell line in serum-free medium for production of bovine alphaherpesvirus-1, Wang, P., Huang, S., Hao, C., Wang, Z., Wang, Z., Zhao, H., Liu, M., Tian, X., Ge, L., Wu, W., Peng, C., 2021 Induction of robust and specific humoral and cellular immune responses by bovine viral diarrhea virus virus-like particles engineered with baculovirus expression system, Wang, Z., Liu, M., Zhao, H., Ma, W., Zhang, Y., Wu, W., Peng, C., 2021 Repair of a newly identified host range gene contributes to full replication of modified vaccinia virus Ankara (MVA) in human cells, Peng, C., Moss B., 2019 Zinc-finger antiviral protein (ZAP) is a restriction factor for replication of modified vaccinia virus Ankara (MVA) in human cells, Peng, C., Wyatt, LS., Glushakow-Smith SG., Lal-Nag, M., Weisberg, AS., Moss, B., 2020 Identification of vaccinia virus inhibitors and cellular functions necessary for efficient viral replication by screening bioactive and FDA-approved drugs, Peng, C., Zhou, Y., Cao, S., Pant, A., Campos Guerrero ML., et al., 2020 Myxoma virus M156 is a specific inhibitor of rabbit PKR but contains a loss-of-function mutation in Australian virus isolates, Peng, C., Haller, S., Rahman, M., McFadden, G. and Rothenburg, S., 2016 Maladaptation after a virus host switch leads to increased activation of the pro-inflammatory NF-κB pathway, Yu, H., Peng, C., Zhang, C. et al., 2022 Orthopoxvirus K3 orthologs show virus- and host-specific inhibition of the antiviral protein kinase PKR, Park, C., Peng, C., Rahman, MJ., Haller, SL., Tazi, L., Brennan, G., Rothenburg, S., 2021

Areas of Focus

Molecular mechanisms of poxvirus host specificity
Development of antiviral drugs, vaccines, and diagnostic reagents for poxvirus diseases
Research on vector vaccines for various infectious diseases using modified vaccinia virus Ankara (MVA)
Development of oncolytic viruses targeting human or pet cancers

Publications

Genomic analysis of Asian variants of Lumpy Skin Disease Virus and an evaluation of its cellular tropism in vitro, Xie, S., Cui, L., Liao, Z., Zhu, J., Ren, S., Niu, K., Li, H., Jiang, F., Wu, J., Wang, J., Wu, W., Peng, C., 2024
DDX5 inhibits inflammation by modulating m6A levels of TLR2/4 transcripts during bacterial infection, Xu, J., Liu, L., Zhi, F., Song, Y., Zhang, Z., Li, B., Zheng, F., Gao, P., Zhang, S., Zhang, Y., Zhang, Y., Qiu, Y., Jiang, B., Li, Y., Peng, C., Chu, Y., 2024
The role of ferroptosis in virus infection, Wang, J., Zhu, J., Ren, S., Zhang, Z., Niu, K., Li, H., Wu, W., Peng, C., 2023
Human Fam111A inhibits vaccinia virus replication by degrading viral protein I3 and is antagonized by poxvirus host range factor SPI-1, Zhu, J., Gao, X., Li, Y., Zhang, Z., Xie, S., Ren, S., Li, Y., Li, H., Niu, K., Fu, S., Deng, Y., Li, Y., Moss, B., Wu, W., Peng, C., 2023
Establishment of a suspension MDBK cell line in serum-free medium for production of bovine alphaherpesvirus-1, Wang, P., Huang, S., Hao, C., Wang, Z., Wang, Z., Zhao, H., Liu, M., Tian, X., Ge, L., Wu, W., Peng, C., 2021
Induction of robust and specific humoral and cellular immune responses by bovine viral diarrhea virus virus-like particles engineered with baculovirus expression system, Wang, Z., Liu, M., Zhao, H., Ma, W., Zhang, Y., Wu, W., Peng, C., 2021
Repair of a newly identified host range gene contributes to full replication of modified vaccinia virus Ankara (MVA) in human cells, Peng, C., Moss B., 2019
Zinc-finger antiviral protein (ZAP) is a restriction factor for replication of modified vaccinia virus Ankara (MVA) in human cells, Peng, C., Wyatt, LS., Glushakow-Smith SG., Lal-Nag, M., Weisberg, AS., Moss, B., 2020
Identification of vaccinia virus inhibitors and cellular functions necessary for efficient viral replication by screening bioactive and FDA-approved drugs, Peng, C., Zhou, Y., Cao, S., Pant, A., Campos Guerrero ML., et al., 2020
Myxoma virus M156 is a specific inhibitor of rabbit PKR but contains a loss-of-function mutation in Australian virus isolates, Peng, C., Haller, S., Rahman, M., McFadden, G. and Rothenburg, S., 2016
Maladaptation after a virus host switch leads to increased activation of the pro-inflammatory NF-κB pathway, Yu, H., Peng, C., Zhang, C. et al., 2022
Orthopoxvirus K3 orthologs show virus- and host-specific inhibition of the antiviral protein kinase PKR, Park, C., Peng, C., Rahman, MJ., Haller, SL., Tazi, L., Brennan, G., Rothenburg, S., 2021

Poxvirus Host Specificity Molecular Mechanisms Antiviral Drugs Vaccines Diagnostic Reagents Vector Vaccines Infectious Diseases Oncolytic Viruses Cancer Therapy

Wei-Huan Fang - Zhejiang University

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