Areas of Focus
- Structural Bioinformatics and AI Drug Design
Work Experience
- 1987-1992 - Postdoctoral Researcher and Research Scholar, University of British Columbia, Canada
- 1993-2006 - Researcher, Canadian Centre for Computational and Its Applications
- 2000 - Professor, Peking University
- 2002-present - Member, Molecular Design Research Center, Concordia University, Canada (part-time)
- 2003-2006 - Distinguished Professor (Haihe Scholar), Tianjin University and Director, Institute of Bioinformatics and Drug Development
- 2006-present - Professor and Distinguished Professor, Department of Bioinformatics and Biostatistics, Shanghai Jiao Tong University
Academic Background & Achievements
- 1987 - PhD from the University of Puerto Rico
- Highly cited scholar with over 600 publications and 15,000 citations
- H-index 66, H10-index 305
Publications
- Thermal decomposition of the solid phase of nitromethane: Ab initio molecular dynamics simulations, Jing Chang, Peng Lian, Dong-Qing Wei*, Xiang-Rong Chen, Zizheng Gong and Qingming Zhang, 2010
- Free Energy Calculations on the Two Drug Binding Sites in the M2 Proton Channel, Ruo-Xu Gu, Limin Angela Liu*, and Dong-Qing Wei*, 2011
- A novel drug candidate for Alzheimer disease treatment - gx-50 derived from Zanthoxylum Bungeanum, Maoping Tang, Zhaoxia Wang, Ying Zhou, Wangjie Xu, Shengtian Li, Lianyun Wang, Dong-Qing Wei*, Zhongdong Qiao*, 2013
- Orientational order in simple dipolar liquids: computer simulation of a ferroelectric nematic phase, Wei, D. and G. Patey, 1992
- Hydrated proton clusters and solvent effects on the proton transfer barrier: A density functional study, Wei, D. and D. Salahub, 1994
- DTI-CDF: a cascade deep forest model towards the prediction of drug-target interactions based on hybrid features, Chu, Y., A.C. Kaushik, X. Wang, W. Wang, Y. Zhang, X. Shan, D.R. Salahub, Y. Xiong, and Wei D.Q., 2019
- Human intestinal defensin 5 inhibits SARS-CoV-2 invasion by cloaking ACE2, Wang, C., Wang, S., Li, D., Wei, D.Q.*, Zhao, J*. and Wang, J.*, 2020
- A transformer-based model to predict peptide–HLA class I binding and optimize mutated peptides for vaccine design, Chu, Y., Zhang, Y., Wang , Q.K., Zhang, L.F., Wang, X.H., Wang, Y.J., , Salahub, D.R., Xu, Q.., Wang, J.M., Jiang, X., Xiong, Y*, and Wei, D.Q.*, 2022
Awards
- Shanghai Science and Technology Progress First Prize
- Second Prize of Chinese Medical Science
- Second Prize of Natural Science by the Computer Society
- Shanghai Jiao Tong University Science and Technology Award
- Fifth Jiao Shanqing Research Award
- Shanghai Jiao Tong University Hengshan Liangci Award
