Fang Wei
Life Science
Shanghai Jiao Tong University
Shanghai
Language: Chinese, English
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Oncogenesis Immunotherapy Tumor Development Cancer Research Immune Response Viral Infection Immune Escape Chronic Disease Cancer Therapy Molecular Targets
Areas of Focus
  • Oncogenesis and development and immunotherapy
  • Chronic virus and cancer immune escape
Work Experience
  • 2013 - Present - Associate Researcher, Shanghai Jiao Tong University, School of Life Sciences and Technology, Sheng Yushou Cell and Immunology Research Center
  • 2010 - 2013 Research Assistant, University of Pennsylvania School of Medicine, Abramson Cancer Research Institute
  • 2008 - 2010 Postdoctoral Fellow, University of Pennsylvania School of Medicine, Abramson Cancer Research Institute
  • 2005 - 2008 Postdoctoral Fellow, University of Pennsylvania School of Veterinary Medicine, Comparative Oncology and Animal Biology Department
  • 2003 - 2005 Research Assistant, University of Virginia, Department of Chemistry
Academic Background & Achievements
  • 2000 - 2003 PhD: Chinese Academy of Medical Sciences, Institute of Cancer Research, National Key Laboratory of Molecular Oncology
  • Received funding from National Natural Science Foundation of China, Shanghai Pujiang Talent Program
Publications
  • CRISPR/Cas9-mediated PD-1 disruption enhances human mesothelin-targeted CAR T cell effector functions, Hu W, Zi Z, Jin Y, Li G, Shao K, Cai Q, Ma X, Wei F*, 2018
  • Strength of PD-1 Signaling Differentially Affects T Cell Effector Functions, Wei F, Zhong S, Ma Z, Kong H, Medvec A, Ahmed R, Freeman G, Krogsgaard M, and Riley JR*, 2013
  • STAT6 degradation and ubiquitylated TRIML2 are essential for activation of human oncogenic herpesvirus, Gu F, Wang C, Wei F, Wang Y, Zhu Q, Ding L, Xu W, Zhu C, Cai C, Qian Z, Yuan Z, Robertson E, Cai Q*, 2018
  • Viral-Mediated AURKB Cleavage Promotes Cell Segregation and Tumorigenesis, Zhu Q, Ding L, Zi Z, Gao S, Wang C, Wang Y, Zhu C, Yuan Z, Wei F, Cai Q*, 2019
  • Establishment of Novel Monoclonal Fabs Specific for Epstein-Barr Virus Encoded Latent Membrane Protein 1, Li G, Ding L, Ma X, Cai Q, Ying T, Wei F*, 2019
  • Progranulin promotes melanoma progression by inhibiting natural killer cell recruitment to the tumor microenvironment, Voshtani R, Song M, Wang H, Li X, Zhang W, Tavallaie M, Yan W, Sun J, Wei F*, Xiaojing Ma*, 2019
  • Lactate induces production of tRNAHis half to promote B-lymphoblastic cell proliferation, Mo X, Du S, Chen X, Wang Y, Liu X, Zhang C, Zhu C, Ding L, Li Y, Tong Y, Ju Q, Qu D, Tan F*, Wei F*, Cai Q*, 2020
  • B7-H3 Chimeric Antigen Receptor Redirected T Cells Target Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma, Zi Z, Zhao H, Wang H, Ma X, Wei F*, 2020
  • Aberrant expression of GOLM1 protects ALK+ anaplastic large cell lymphoma from apoptosis by enhancing BCL-XL stability, Zi Z, Du S, Zhang L, Wang Y, Ding L, Zhang C, Wang H, Pawlicki J, Cai Y, Yao Y, Zhou F, Tong Y, Riley JL, Cai Q, Ma X, Wei F*, 2023
  • UBR5 promotes tumor immune evasion through enhancing IFN-g-induced PDL1 transcription in triple negative breast cancer, Wu B, Song M, Dong Q, Xiang G, Li J, Ma X, Wei F*, 2022
Awards
  • 2021: Third Prize in the Sixth Teaching Competition of the School of Life Sciences
  • 2014: Shanghai Pujiang Talent
  • 2012: Best Paper Award, FOCiS International Conference
  • 2003: Second Prize for Research on Esophageal Cancer Genes and Proteins, Chinese Medical Association
  • 2002: Outstanding Paper, Annual Meeting of the Chinese Academy of Medical Sciences
  • 2002: Second Prize, Tianheng Cup of the Cancer Institute of the Chinese Academy of Medical Sciences
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