Professor | Fang Wei | Asia Growth Partners

Name	Fang Wei
Contact Information	fangwei@sjtu.edu.cn
Language ability	Chinese, English
Province	Shanghai

Name

Fang Wei

Contact Information

fangwei@sjtu.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Shanghai Jiao Tong University
Faculty	Life Sciences
Academic Background & Achievements	2000 - 2003 PhD: Chinese Academy of Medical Sciences, Institute of Cancer Research, National Key Laboratory of Molecular Oncology Received funding from National Natural Science Foundation of China, Shanghai Pujiang Talent Program
Work Experience	2013 - Present - Associate Researcher, Shanghai Jiao Tong University, School of Life Sciences and Technology, Sheng Yushou Cell and Immunology Research Center 2010 - 2013 Research Assistant, University of Pennsylvania School of Medicine, Abramson Cancer Research Institute 2008 - 2010 Postdoctoral Fellow, University of Pennsylvania School of Medicine, Abramson Cancer Research Institute 2005 - 2008 Postdoctoral Fellow, University of Pennsylvania School of Veterinary Medicine, Comparative Oncology and Animal Biology Department 2003 - 2005 Research Assistant, University of Virginia, Department of Chemistry
Awards	2021: Third Prize in the Sixth Teaching Competition of the School of Life Sciences 2014: Shanghai Pujiang Talent 2012: Best Paper Award, FOCiS International Conference 2003: Second Prize for Research on Esophageal Cancer Genes and Proteins, Chinese Medical Association 2002: Outstanding Paper, Annual Meeting of the Chinese Academy of Medical Sciences 2002: Second Prize, Tianheng Cup of the Cancer Institute of the Chinese Academy of Medical Sciences

University/Lab Affiliation and Title

Shanghai Jiao Tong University

Faculty

Life Sciences

Academic Background & Achievements

2000 - 2003 PhD: Chinese Academy of Medical Sciences, Institute of Cancer Research, National Key Laboratory of Molecular Oncology
Received funding from National Natural Science Foundation of China, Shanghai Pujiang Talent Program

Work Experience

2013 - Present - Associate Researcher, Shanghai Jiao Tong University, School of Life Sciences and Technology, Sheng Yushou Cell and Immunology Research Center
2010 - 2013 Research Assistant, University of Pennsylvania School of Medicine, Abramson Cancer Research Institute
2008 - 2010 Postdoctoral Fellow, University of Pennsylvania School of Medicine, Abramson Cancer Research Institute
2005 - 2008 Postdoctoral Fellow, University of Pennsylvania School of Veterinary Medicine, Comparative Oncology and Animal Biology Department
2003 - 2005 Research Assistant, University of Virginia, Department of Chemistry

Awards

2021: Third Prize in the Sixth Teaching Competition of the School of Life Sciences
2014: Shanghai Pujiang Talent
2012: Best Paper Award, FOCiS International Conference
2003: Second Prize for Research on Esophageal Cancer Genes and Proteins, Chinese Medical Association
2002: Outstanding Paper, Annual Meeting of the Chinese Academy of Medical Sciences
2002: Second Prize, Tianheng Cup of the Cancer Institute of the Chinese Academy of Medical Sciences

Areas of Focus	Oncogenesis and development and immunotherapy Chronic virus and cancer immune escape
Publications	CRISPR/Cas9-mediated PD-1 disruption enhances human mesothelin-targeted CAR T cell effector functions, Hu W, Zi Z, Jin Y, Li G, Shao K, Cai Q, Ma X, Wei F, 2018 Strength of PD-1 Signaling Differentially Affects T Cell Effector Functions, Wei F, Zhong S, Ma Z, Kong H, Medvec A, Ahmed R, Freeman G, Krogsgaard M, and Riley JR, 2013 STAT6 degradation and ubiquitylated TRIML2 are essential for activation of human oncogenic herpesvirus, Gu F, Wang C, Wei F, Wang Y, Zhu Q, Ding L, Xu W, Zhu C, Cai C, Qian Z, Yuan Z, Robertson E, Cai Q, 2018 Viral-Mediated AURKB Cleavage Promotes Cell Segregation and Tumorigenesis, Zhu Q, Ding L, Zi Z, Gao S, Wang C, Wang Y, Zhu C, Yuan Z, Wei F, Cai Q, 2019 Establishment of Novel Monoclonal Fabs Specific for Epstein-Barr Virus Encoded Latent Membrane Protein 1, Li G, Ding L, Ma X, Cai Q, Ying T, Wei F, 2019 Progranulin promotes melanoma progression by inhibiting natural killer cell recruitment to the tumor microenvironment, Voshtani R, Song M, Wang H, Li X, Zhang W, Tavallaie M, Yan W, Sun J, Wei F, Xiaojing Ma, 2019 Lactate induces production of tRNAHis half to promote B-lymphoblastic cell proliferation, Mo X, Du S, Chen X, Wang Y, Liu X, Zhang C, Zhu C, Ding L, Li Y, Tong Y, Ju Q, Qu D, Tan F, Wei F, Cai Q, 2020 B7-H3 Chimeric Antigen Receptor Redirected T Cells Target Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma, Zi Z, Zhao H, Wang H, Ma X, Wei F, 2020 Aberrant expression of GOLM1 protects ALK+ anaplastic large cell lymphoma from apoptosis by enhancing BCL-XL stability, Zi Z, Du S, Zhang L, Wang Y, Ding L, Zhang C, Wang H, Pawlicki J, Cai Y, Yao Y, Zhou F, Tong Y, Riley JL, Cai Q, Ma X, Wei F, 2023 UBR5 promotes tumor immune evasion through enhancing IFN-g-induced PDL1 transcription in triple negative breast cancer, Wu B, Song M, Dong Q, Xiang G, Li J, Ma X, Wei F*, 2022

Areas of Focus

Oncogenesis and development and immunotherapy
Chronic virus and cancer immune escape

Publications

CRISPR/Cas9-mediated PD-1 disruption enhances human mesothelin-targeted CAR T cell effector functions, Hu W, Zi Z, Jin Y, Li G, Shao K, Cai Q, Ma X, Wei F*, 2018
Strength of PD-1 Signaling Differentially Affects T Cell Effector Functions, Wei F, Zhong S, Ma Z, Kong H, Medvec A, Ahmed R, Freeman G, Krogsgaard M, and Riley JR*, 2013
STAT6 degradation and ubiquitylated TRIML2 are essential for activation of human oncogenic herpesvirus, Gu F, Wang C, Wei F, Wang Y, Zhu Q, Ding L, Xu W, Zhu C, Cai C, Qian Z, Yuan Z, Robertson E, Cai Q*, 2018
Viral-Mediated AURKB Cleavage Promotes Cell Segregation and Tumorigenesis, Zhu Q, Ding L, Zi Z, Gao S, Wang C, Wang Y, Zhu C, Yuan Z, Wei F, Cai Q*, 2019
Establishment of Novel Monoclonal Fabs Specific for Epstein-Barr Virus Encoded Latent Membrane Protein 1, Li G, Ding L, Ma X, Cai Q, Ying T, Wei F*, 2019
Progranulin promotes melanoma progression by inhibiting natural killer cell recruitment to the tumor microenvironment, Voshtani R, Song M, Wang H, Li X, Zhang W, Tavallaie M, Yan W, Sun J, Wei F*, Xiaojing Ma*, 2019
Lactate induces production of tRNAHis half to promote B-lymphoblastic cell proliferation, Mo X, Du S, Chen X, Wang Y, Liu X, Zhang C, Zhu C, Ding L, Li Y, Tong Y, Ju Q, Qu D, Tan F*, Wei F*, Cai Q*, 2020
B7-H3 Chimeric Antigen Receptor Redirected T Cells Target Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma, Zi Z, Zhao H, Wang H, Ma X, Wei F*, 2020
Aberrant expression of GOLM1 protects ALK+ anaplastic large cell lymphoma from apoptosis by enhancing BCL-XL stability, Zi Z, Du S, Zhang L, Wang Y, Ding L, Zhang C, Wang H, Pawlicki J, Cai Y, Yao Y, Zhou F, Tong Y, Riley JL, Cai Q, Ma X, Wei F*, 2023
UBR5 promotes tumor immune evasion through enhancing IFN-g-induced PDL1 transcription in triple negative breast cancer, Wu B, Song M, Dong Q, Xiang G, Li J, Ma X, Wei F*, 2022

Oncogenesis Immunotherapy Tumor Development Cancer Research Immune Response Viral Infection Immune Escape Chronic Disease Cancer Therapy Molecular Targets

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