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Pengxu Qian
axu@zju.edu.cn
Chinese, English
Zhejiang
Zhejiang University
Medical
  • 2007.09-2012.07 Ph.D. in Cell Biology: University of Science and Technology of China
  • 2002.09-2006.07 Bachelor's in Biological Sciences: University of Science and Technology of China
  • National Talent Program Awardee (2018)
  • National Natural Science Foundation Excellent Young Scientist Fund Awardee (2022)
  • Chief Scientist of the National Key R&D Program 'Stem Cell and Translational Research' Youth Project (2018)
  • Member of various national academic committees
  • 2017.11-present - Zhejiang University School of Medicine - Researcher of the 'Hundred Talents Program', Doctoral Supervisor
  • 2012.08-2017.10 - Stowers Institute for Medical Research, USA - Postdoctoral Researcher
  • 2018: First Prize at the First Stem Cell Youth Forum of China Stem Cell
  • 2017: Chen Mei Zhongmei Travel Award at the 15th Annual Meeting of the International Society for Stem Cell Research (ISSCR)
  • 2016: Outstanding Abstract Award at the 58th Annual Meeting of the American Society of Hematology (ASH)
  • 2015: Outstanding Abstract Award at the 57th Annual Meeting of the American Society of Hematology (ASH)
  • 2015: ASH Scholar Award
  • 2014: Outstanding Abstract Award at the 56th Annual Meeting of the American Society of Hematology (ASH)
  • 2012: Qiu Shi Graduate Student Scholarship
  • 2010: Zhu Li Yuehua Scholarship of the Chinese Academy of Sciences
Hematopoietic Stem Cells
Epigenetics
Hematological Diseases
Cellular Immunotherapy
Hematological Effects of Nanomaterials
  • Artemin stimulates oncogenicity and invasiveness of human endometrial carcinoma cells, Pandey V, Qian PX, Kang J, Perry JK, Mitchell MD, Yin Z, Wu ZS, Liu DX, Zhu T, Lobie PE, 2010
  • Pivotal role of reduced let-7g expression in breast cancer invasion and metastasis, Qian P, Zuo Z, Wu Z, Meng X, Li G, Wu Z, Zhang W, Tan S, Pandey V, Yao Y, Wang P, Zhao L, Wang J, Wu Q, Song E, Lobie PE, Yin Z, Zhu T, 2011
  • Loss of SNAIL regulated miR-128-2 on chromosome 3p22.3 targets multiple stem cell factors to promote transformation of mammary epithelial cells, Qian P, Banerjee A, Wu ZS, Zhang X, Wang H, Pandey V, Zhang WJ, Lv XF, Tan S, Lobie PE, Zhu T, 2012
  • Artemin stimulates radio- and chemo-resistance by promoting TWIST1-BCL-2-dependent cancer stem cell-like behavior in mammary carcinoma cells, Banerjee A, Qian P, Wu ZS, Ren X, Steiner M, Bougen NM, Liu S, Liu DX, Zhu T, Lobie PE, 2012
  • Gd-metallofullerenol nanomaterial as non-toxic breast cancer stem cell-specific inhibitor, Liu Y, Chen C, Qian P, Lu X, Sun B, Zhang X, Wang L, Gao X, Li H, Chen Z, Tang J, Zhang W, Dong J, Bai R, Lobie PE, Wu Q, Liu S, Zhang H, Zhao F, Wicha MS, Zhu T, Zhao Y, 2015
  • Autocrine/paracrine human growth hormone stimulated miRNA 96-182-183 clusters promotes epithelial-mesenchymal transition and invasion in breast cancer, Zhang W, Qian P, Zhang X, Zhang M, Wang H, Wu M, Kong X, Tan S, Ding K, Perry JK, Wu Z, Cao Y, Lobie PE, Zhu T, 2015
  • The Dlk1-Gtl2 Locus Preserves LT-HSC Function by Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism, Qian P, He XC, Paulson A, Li Z, Tao F, Perry JM, Guo F, Zhao M, Zhi L, Venkatraman A, Haug JS, Parmely T, Li H, Dobrowsky RT, Ding WX, Kono T, Ferguson-Smith AC, Li L, 2016
  • Single-cell RNA-seq technology lends a hand into HSC ontogeny, Qian P, Li L, 2016
  • Retinoid-Sensitive Epigenetic Regulation of the Hoxb Cluster Maintains Normal Hematopoiesis and Inhibits Leukemogenesis, Qian P, De Kumar B, He XC, Nolte C, Gogol M, Ahn Y, Chen S, Li Z, Xu H, Perry JM, Hu D, Tao F, Zhao M, Han Y, Hall K, Peak A, Dukes D, Paulson A, Venkatraman A, Box A, Perera A, Haug JS, Parmely T, Li H, Krumlauf R, Li L, 2018
  • Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion, Li Z, Qian P, Shao W, Shi H, He XC, Gogol M, Yu Z, Wang Y, Qi M, Zhu Y, Perry JM, Zhang K, Tao F, Zhou K, Hu D, Han Y, Zhao C, Alexander R, Xu H, Chen S, Peak A, Hall K, Peterson M, Perera A, Haug JS, Parmely T, Li H, Shen B, Zeitlinger J, He C, Li L, 2018
  • Epigenetic regulation of hematopoietic stem cell homeostasis, Jiang P, Wang H, Zheng J, Han Y, Huang H, Qian P, 2019
  • Virus Strain From a Mild COVID-19 Patient in Hangzhou Represents a New Trend in SARS-CoV-2 Evolution Potentially Related to Furin Cleavage Site, Jin X, Xu K, Jiang P, Lian J, Hao S, Yao H, Jia H, Zhang Y, Zheng L, Zheng N, Chen D, Yao J, Hu J, Gao J, Wen L, Shen J, Ren Y, Yu G, Wang X, Lu Y, Yu X, Yu L, Xiang D, Wu N, Lu X, Cheng L, Liu F, Wu H, Jin C, Yang X, Qian P, Qiu Y, Sheng J, Liang T, Li L, Yang Y, 2020
  • Tyrosine Supplement Ameliorates Murine aGVHD by Modulation of Gut Microbiome and Metabolome, Xiaoqing Li, Yu Lin, Xue Li, Xiaoxiao Xu, Yanmin Zhao, Lin Xu, Yang Gao, Yixue Li, Yamin Tan, Pengxu Qian, He Huang, 2020
  • Generation of a FTO gene knockout human embryonic stem cell line using CRISPR/Cas9 editing, Cong Wei, Qian Luo, Binsheng Wang, Yan Long, Meng Zhang, Wei Shan, Xiaohong Yu, Yulin Xu, Pengxu Qian, He Huang, 2021
  • Generation of an ELTD1 knockout human embryonic stem cell line by the iCRISPR/Cas9 system, Qian Luo, Cong Wei, Yan Long, Meng Zhang, Wei Shan, Honghu Li, Shuyang Cai, Yulin Xu, Pengxu Qian, He Huang, 2021
  • Enhanced HSC-like cell generation from mouse pluripotent stem cells in a 3D induction system cocultured with stromal cells, Shan W, Yu Q, Long Y, Luo Q, Li H, Han Y, Xu Y, Fu S, Zeng X, Wei C, Gao Y, Li X, Li X, Zhang L, Liu L, Chen M, Qian P, Huang H, 2021
  • Biomechanical cues as master regulators of hematopoietic stem cell fate, Li H, Luo Q, Shan W, Cai S, Tie R, Xu Y, Lin Y, Qian P, Huang H, 2021
  • Dasatinib enhances anti-leukemia efficacy of chimeric antigen receptor T cells by inhibiting cell differentiation and exhaustion, Zhang H, Hu Y, Shao M, Teng X, Jiang P, Wang X, Wang H, Cui J, Yu J, Liang Z, Ding L, Han Y, Wei J, Xu Y, Li X, Shan W, Shi J, Luo Y, Qian P, Huang H, 2021
  • Programmable System of Cas13-Mediated RNA Modification and Its Biological and Biomedical Applications, Tian Tang, Yingli Han, Yuran Wang, He Huang, Pengxu Qian, 2021
  • Specific Blood Cells Derived from Pluripotent Stem Cells: An Emerging Field with Great Potential in Clinical Cell Therapy, Qian Luo, Honghu Li, Wei Shan, Cong Wei, Yan Long, Shuyang Cai, Xiangjun Zeng, Xue Li, Yulin Xu, Xiaoxiao Xu, Yi Luo, Pengxu Qian, He Huang, 2021
  • Signaling pathways in the regulation of cytokine release syndrome in human diseases and intervention therapy, Xia Li, Mi Shao, Xiangjun Zeng, Pengxu Qian, He Huang, 2021
  • Integrated Single-Cell Bioinformatics Analysis Reveals Intrinsic and Extrinsic Biological Characteristics of Hematopoietic Stem Cell Aging, Xiangjun Zeng, Xia Li, Mi Shao, Yulin Xu, Wei Shan, Cong Wei, Xiaoqing Li, Limengmeng Wang, Yongxian Hu, Yanmin Zhao, Pengxu Qian, He Huang, 2021
  • Inhibition of Calcium Signaling Prevents Exhaustion and Enhances Anti-Leukemia Efficacy of CAR-T Cells via SOCE-Calcineurin-NFAT and Glycolysis Pathways, Mi Shao, Xinyi Teng, Xin Guo, Hao Zhang, Yue Huang, Jiazhen Cui
Stem Cells Hematopoiesis Blood Regeneration Transplantation Epigenetic Regulation Gene Expression Cancer Therapy Nanotechnology

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