Areas of Focus
- 13C Metabolic Flux Analysis
- Development of computational analysis methods and software platforms for industrial microbial metabolism
- Mechanisms of major diseases' onset, progression, and outcomes
Work Experience
- 2013-10 - Present: Department of Bioengineering, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University
- 2020-12 - Present: Associate Researcher at Shanghai Jiao Tong University
Academic Background & Achievements
- 2006 - Bachelor's Degree in Applied Physics from East China University of Science and Technology
- 2013 - PhD in Information Engineering from Kyushu Institute of Technology, Japan
Publications
- 13C metabolic flux analysis development over 30 years, Ruilian Yao, 2021
- 13C metabolic flux analysis-guided metabolic engineering of Escherichia coli for improved acetol production from glycerol, Ruilian Yao, Jiawei Li, Lei Feng, Xuehong Zhang, Hongbo Hu, 2019
- CRISPR-Cas9/Cas12a biotechnology and application in bacteria, Ruilian Yao, Di Liu, Xiao Jia, Yuan Zheng, Wei Liu, Yi Xiao, 2018
- Engineering and systems-level analysis of Pseudomonas chlororaphis for production of phenazine-1-carboxamide using glycerol as the cost-effective carbon source, Ruilian Yao, Keli Pan, Huasong Peng, Lei Feng, Hongbo Hu, Xuehong Zhang, 2018
- Elucidation of the co-metabolism of glycerol and glucose in Escherichia coli by genetic engineering, transcription, profiling, and 13C metabolic flux analysis, Ruilian Yao, Dewang Xiong, Hongbo Hu, Masataka Wakayama, Wenjuan Yu, Xuehong Zhang, Kazuyuki Shimizu, 2016
- Metabolic engineering of Escherichia coli to enhance acetol production from glycerol, Ruilian Yao, Qing Liu, Hongbo Hu, Thomas K. Wood, Xuehong Zhang, 2015