Professor | Ming Yu | Asia Growth Partners

Name	Ming Yu
Contact Information	mingyu@sjtu.edu.cn
Language ability	English, Chinese
Province	Shanghai

Name

Ming Yu

Contact Information

mingyu@sjtu.edu.cn

Language ability

English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	Shanghai Jiao Tong University
Faculty	Life Sciences
Academic Background & Achievements	1996 – 2000 Bachelor in Microbiology, Inner Mongolia University College of Life Sciences 2000 – 2005 PhD in Biochemistry and Molecular Biology, Peking University College of Life Sciences 2005 – 2007 Postdoctoral Researcher, Department of Immunobiology, Yale University School of Medicine 2007 – 2010 Postdoctoral Researcher, Boston Children’s Hospital, Harvard Medical School 2010 – 2015 Postdoctoral Researcher, Laboratory of Biochemistry & Molecular Biology, The Rockefeller University
Work Experience	2016 – 2022 Associate Professor, Shanghai Jiao Tong University School of Life Sciences and Technology 2022 – Present Associate Professor, Shanghai Jiao Tong University School of Life Sciences and Technology

University/Lab Affiliation and Title

Shanghai Jiao Tong University

Faculty

Life Sciences

Academic Background & Achievements

1996 – 2000 Bachelor in Microbiology, Inner Mongolia University College of Life Sciences
2000 – 2005 PhD in Biochemistry and Molecular Biology, Peking University College of Life Sciences
2005 – 2007 Postdoctoral Researcher, Department of Immunobiology, Yale University School of Medicine
2007 – 2010 Postdoctoral Researcher, Boston Children’s Hospital, Harvard Medical School
2010 – 2015 Postdoctoral Researcher, Laboratory of Biochemistry & Molecular Biology, The Rockefeller University

Work Experience

2016 – 2022 Associate Professor, Shanghai Jiao Tong University School of Life Sciences and Technology
2022 – Present Associate Professor, Shanghai Jiao Tong University School of Life Sciences and Technology

Areas of Focus	Hematopoietic development and cancer transcription and epigenetic regulation
Publications	Tox4 regulates transcriptional elongation and reinitiation during murine T cell development, Wang, T., Zhao, R., Zhi, J., Liu, Z., Wu, A., Yang, Z., Wang, W., Ni, T., Jing, L., and Yu, M., 2023 TOX4 facilitates promoter-proximal pausing and C-terminal domain dephosphorylation of RNA polymerase II in human cells, Liu, Z., Wu, A., Wu, Z., Wang, T., Pan, Y., Li, B., Zhang, X., and Yu, M., 2022 DOT1L complex regulates transcriptional initiation in human erythroleukemic cells, Wu, A., Zhi, J., Tian, T., Cihan, A., Cevher, M., Liu, Z., David, Y., Muir, T.W., Roeder, R.G., and Yu, M., 2021 Intramolecular chaperone-mediated secretion of an Rhs effector toxin by a type VI secretion system, Pei, T. T., Li, H., Liang, X., Wang, Z. H., Liu, G., Wu, L. L., Kim, H., Xie, Z., Yu, M., Lin, S., Xu, P., and Dong, T. G., 2020 RNA polymerase II-associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II, Yu, M., Yang, W., Ni, T., Tang, Z., Nakadai, T., Zhu, J., and Roeder, R.G., 2015 Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia, Wang, E., Kawaoka, S., Yu, M., Shi, J., Ni, T., Yang, W., Zhu, J., Roeder, R. G., and Vakoc, C. R., 2013 Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors, Yu, M., Mazor, T., Huang, H., Huang, H. T., Kathrein, K. L., Woo, A. J., Chouinard, C. R., Labadorf, A., Akie, T. E., Moran, T. B., Xie, H., Zacharek, S., Taniuchi, I., Roeder, R. G., Kim, C. F., Zon, L. I., Fraenkel, E., and Cantor, A. B., 2012 Identification of Distal cis-Regulatory Elements at Mouse Mitoferrin Loci Using Zebrafish Transgenesis, Amigo, J. D., Yu, M., Troadec, M. B., Gwynn, B., Cooney, J. D., Lambert, A. J., Chi, N. C., Weiss, M. J., Peters, L. L., Kaplan, J., Cantor, A. B., and Paw, B. H., 2011 Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis, Yu, M., Riva, L., Xie, H., Schindler, Y., Moran, T. B., Cheng, Y., Yu, D., Hardison, R., Weiss, M. J., Orkin, S. H., Bernstein, B. E., Fraenkel, E., and Cantor, A. B., 2009 Differentiation-dependent interactions between RUNX-1 and FLI-1 during megakaryocyte development, Huang, H., Yu, M., Akie, T. E., Moran, T. B., Woo, A. J., Tu, N., Waldon, Z., Lin, Y. Y., Steen, H., and Cantor, A. B., 2009

Areas of Focus

Hematopoietic development and cancer transcription and epigenetic regulation

Publications

Tox4 regulates transcriptional elongation and reinitiation during murine T cell development, Wang, T., Zhao, R., Zhi, J., Liu, Z., Wu, A., Yang, Z., Wang, W., Ni, T., Jing, L., and Yu, M., 2023
TOX4 facilitates promoter-proximal pausing and C-terminal domain dephosphorylation of RNA polymerase II in human cells, Liu, Z., Wu, A., Wu, Z., Wang, T., Pan, Y., Li, B., Zhang, X., and Yu, M., 2022
DOT1L complex regulates transcriptional initiation in human erythroleukemic cells, Wu, A., Zhi, J., Tian, T., Cihan, A., Cevher, M., Liu, Z., David, Y., Muir, T.W., Roeder, R.G., and Yu, M., 2021
Intramolecular chaperone-mediated secretion of an Rhs effector toxin by a type VI secretion system, Pei, T. T., Li, H., Liang, X., Wang, Z. H., Liu, G., Wu, L. L., Kim, H., Xie, Z., Yu, M., Lin, S., Xu, P., and Dong, T. G., 2020
RNA polymerase II-associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II, Yu, M., Yang, W., Ni, T., Tang, Z., Nakadai, T., Zhu, J., and Roeder, R.G., 2015
Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia, Wang, E., Kawaoka, S., Yu, M., Shi, J., Ni, T., Yang, W., Zhu, J., Roeder, R. G., and Vakoc, C. R., 2013
Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors, Yu, M., Mazor, T., Huang, H., Huang, H. T., Kathrein, K. L., Woo, A. J., Chouinard, C. R., Labadorf, A., Akie, T. E., Moran, T. B., Xie, H., Zacharek, S., Taniuchi, I., Roeder, R. G., Kim, C. F., Zon, L. I., Fraenkel, E., and Cantor, A. B., 2012
Identification of Distal cis-Regulatory Elements at Mouse Mitoferrin Loci Using Zebrafish Transgenesis, Amigo, J. D., Yu, M., Troadec, M. B., Gwynn, B., Cooney, J. D., Lambert, A. J., Chi, N. C., Weiss, M. J., Peters, L. L., Kaplan, J., Cantor, A. B., and Paw, B. H., 2011
Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis, Yu, M., Riva, L., Xie, H., Schindler, Y., Moran, T. B., Cheng, Y., Yu, D., Hardison, R., Weiss, M. J., Orkin, S. H., Bernstein, B. E., Fraenkel, E., and Cantor, A. B., 2009
Differentiation-dependent interactions between RUNX-1 and FLI-1 during megakaryocyte development, Huang, H., Yu, M., Akie, T. E., Moran, T. B., Woo, A. J., Tu, N., Waldon, Z., Lin, Y. Y., Steen, H., and Cantor, A. B., 2009

Hematopoiesis Cancer Transcription Epigenetics Genomics Crispr-Cas9 Proteomics Mouse Genetics Paf1 Complex Super Elongation Complex

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