Areas of Focus
- Hematopoietic development and cancer transcription and epigenetic regulation
Work Experience
- 2016 – 2022 Associate Professor, Shanghai Jiao Tong University School of Life Sciences and Technology
- 2022 – Present Associate Professor, Shanghai Jiao Tong University School of Life Sciences and Technology
Academic Background & Achievements
- 1996 – 2000 Bachelor in Microbiology, Inner Mongolia University College of Life Sciences
- 2000 – 2005 PhD in Biochemistry and Molecular Biology, Peking University College of Life Sciences
- 2005 – 2007 Postdoctoral Researcher, Department of Immunobiology, Yale University School of Medicine
- 2007 – 2010 Postdoctoral Researcher, Boston Children’s Hospital, Harvard Medical School
- 2010 – 2015 Postdoctoral Researcher, Laboratory of Biochemistry & Molecular Biology, The Rockefeller University
Publications
- Tox4 regulates transcriptional elongation and reinitiation during murine T cell development, Wang, T., Zhao, R., Zhi, J., Liu, Z., Wu, A., Yang, Z., Wang, W., Ni, T., Jing, L., and Yu, M., 2023
- TOX4 facilitates promoter-proximal pausing and C-terminal domain dephosphorylation of RNA polymerase II in human cells, Liu, Z., Wu, A., Wu, Z., Wang, T., Pan, Y., Li, B., Zhang, X., and Yu, M., 2022
- DOT1L complex regulates transcriptional initiation in human erythroleukemic cells, Wu, A., Zhi, J., Tian, T., Cihan, A., Cevher, M., Liu, Z., David, Y., Muir, T.W., Roeder, R.G., and Yu, M., 2021
- Intramolecular chaperone-mediated secretion of an Rhs effector toxin by a type VI secretion system, Pei, T. T., Li, H., Liang, X., Wang, Z. H., Liu, G., Wu, L. L., Kim, H., Xie, Z., Yu, M., Lin, S., Xu, P., and Dong, T. G., 2020
- RNA polymerase II-associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II, Yu, M., Yang, W., Ni, T., Tang, Z., Nakadai, T., Zhu, J., and Roeder, R.G., 2015
- Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia, Wang, E., Kawaoka, S., Yu, M., Shi, J., Ni, T., Yang, W., Zhu, J., Roeder, R. G., and Vakoc, C. R., 2013
- Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors, Yu, M., Mazor, T., Huang, H., Huang, H. T., Kathrein, K. L., Woo, A. J., Chouinard, C. R., Labadorf, A., Akie, T. E., Moran, T. B., Xie, H., Zacharek, S., Taniuchi, I., Roeder, R. G., Kim, C. F., Zon, L. I., Fraenkel, E., and Cantor, A. B., 2012
- Identification of Distal cis-Regulatory Elements at Mouse Mitoferrin Loci Using Zebrafish Transgenesis, Amigo, J. D., Yu, M., Troadec, M. B., Gwynn, B., Cooney, J. D., Lambert, A. J., Chi, N. C., Weiss, M. J., Peters, L. L., Kaplan, J., Cantor, A. B., and Paw, B. H., 2011
- Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis, Yu, M., Riva, L., Xie, H., Schindler, Y., Moran, T. B., Cheng, Y., Yu, D., Hardison, R., Weiss, M. J., Orkin, S. H., Bernstein, B. E., Fraenkel, E., and Cantor, A. B., 2009
- Differentiation-dependent interactions between RUNX-1 and FLI-1 during megakaryocyte development, Huang, H., Yu, M., Akie, T. E., Moran, T. B., Woo, A. J., Tu, N., Waldon, Z., Lin, Y. Y., Steen, H., and Cantor, A. B., 2009