Professor | Dante Neculai | Asia Growth Partners

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Name	Dante Neculai
Contact Information	dneculai@zju.edu.cn
Language ability	English, German, Chinese
Province	Zhejiang

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Name

Dante Neculai

Contact Information

dneculai@zju.edu.cn

Language ability

English, German, Chinese

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Medical
Academic Background & Achievements	2003 - PhD in Chemistry: University of Göttingen, Germany Discovered channel-like cavity structure in CD36 superfamily proteins (Nature, 2013) Identified molecular mechanism of HLTF protein in DNA repair (Nucleic Acids Research, 2015) Revealed LIMP-2 and NPC protein interaction (Nat Communs, 2019) Discovered palmitoylation modification in NOD1 and NOD2 (Science, 2019) Proposed dynamic regulation model for ER-Phagy (EMBO J, 2020)
Work Experience	Postdoctoral Research - Max Planck Institute for Biophysical Chemistry, Germany Postdoctoral Research - Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Canada 2009-2014 - Researcher - University of Toronto, Ontario Cancer Institute, and Hospital for Sick Children, Canada

University/Lab Affiliation and Title

Zhejiang University

Faculty

Medical

Academic Background & Achievements

2003 - PhD in Chemistry: University of Göttingen, Germany
Discovered channel-like cavity structure in CD36 superfamily proteins (Nature, 2013)
Identified molecular mechanism of HLTF protein in DNA repair (Nucleic Acids Research, 2015)
Revealed LIMP-2 and NPC protein interaction (Nat Communs, 2019)
Discovered palmitoylation modification in NOD1 and NOD2 (Science, 2019)
Proposed dynamic regulation model for ER-Phagy (EMBO J, 2020)

Work Experience

Postdoctoral Research - Max Planck Institute for Biophysical Chemistry, Germany
Postdoctoral Research - Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Canada
2009-2014 - Researcher - University of Toronto, Ontario Cancer Institute, and Hospital for Sick Children, Canada

Areas of Focus	Lipid Metabolism Innate Immunity Protein Post-Translational Modifications
Publications	Channel-like cavity structure in CD36 superfamily proteins, Dante Neculai, 2013 Molecular mechanism of HLTF protein in DNA repair, Dante Neculai, 2015 LIMP-2 and NPC protein interaction, Dante Neculai, 2019 Palmitoylation modification in NOD1 and NOD2, Dante Neculai, 2019 Dynamic regulation model for ER-Phagy, Dante Neculai, 2020

Areas of Focus

Lipid Metabolism
Innate Immunity
Protein Post-Translational Modifications

Publications

Channel-like cavity structure in CD36 superfamily proteins, Dante Neculai, 2013
Molecular mechanism of HLTF protein in DNA repair, Dante Neculai, 2015
LIMP-2 and NPC protein interaction, Dante Neculai, 2019
Palmitoylation modification in NOD1 and NOD2, Dante Neculai, 2019
Dynamic regulation model for ER-Phagy, Dante Neculai, 2020

Lipid Metabolism: Cholesterol Cd36 Sr-Bi Limp-2 Lipid Transport Cell Membrane Innate Immunity Molecular Mechanism Antigen Recognition Lipid Synthesis Innate Immunity: Nod1 Nod2 Zdhhc5 Palmitoylation Pathogen Recognition Immune Response Genetic Markers Inflammatory Bowel Disease Resistance Host Defense Protein Post-Translational Modifications: Hltf Dna Repair Hiran Domain Protein Interaction Molecular Biology Cell Replication Structural Biology Protein Synthesis Post-Translational Protein Regulation

Linyu Lu - Zhejiang University

Ting Liu - Zhejiang University

Yidan Liu - Zhejiang University

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