MDGA2 constrains glutamatergic inputs selectively onto CA1 pyramidal neurons to optimize neural circuits for plasticity, memory and social behavior, Wang, X., Lin, D., Jiang, J., Liu, Y., Dong, X., Fan, J., Gong, L., Shen, W., Zeng, L., Xu, T., Jiang, K., Connor, SA., Xie, Y., 2024
Inhalation of panaxadiol alleviates lung inflammation via inhibiting TNFA/TNFAR and IL7/ IL7R signaling between macrophages and epithelial cells, Wang, Y., Wei, H., Song, Z., Jiang, L., Zhang, M., Lu, X., Li, W., Zhao, Y., Wu, L., Li, S., Shen, H., Shu, Q., Xie, Y., 2024
Trpm2 deficiency in microglia attenuates neuroinflammation during epileptogensis by upregulating autophagy via the AMPK/mTOR pathway, Chen, C., Zhu, T., Gong, L., Gong, L., Hu, Z., Wei, H., Fan, J., Lin, D., Wang, X., Xu, J., Dong, X., Wang, Y., Xia, N., Zeng, L., Jiang, P., Xie, Y., 2023
Preferential pruning of inhibitory synapses by microglia contributes to alteration of the balance between excitatory and inhibitory synapses in the hippocampus in temporal lobe epilepsy, Fan, J, Dong, X., Tang, Y., Wang, X., Lin, D., Gong, L., Chen, C., Jiang, J., Shen, W., Xu, A., Zhang, X., Xie, Y., Huang, X., and Zeng, L., 2023
Dual roles of hexokinase 2 in shaping microglial function by gating glycolytic flux and mitochondrial activity, Hu Y, Cao K, Wang F, Wu W, Mai W, Qiu L, Luo Y, Ge WP, Sun B, Shi L, Zhu J, Zhang J, Wu Z, Xie Y, Duan S, Gao Z., 2022
Single-Cell Transcriptomic Characterization Reveals the Landscape of Airway Remodeling and Inflammation in a Cynomolgus Monkey Model of Asthma, Wang, Y., Dong, X., Pan, C., Zhu, C., Shen, H., Li, S., Xie, Y., 2022
Captopril Alleviates Epilepsy and Cognitive Impairment by Attenuation of C3-Mediated Inflammation and Synaptic Phagocytosis, Dong, X., Fan, J., Lin, D., Wang, X., Kuang, H., Gong, L., Chen, C., Jiang, J., Xia, N., He, D., Shen, W., Jiang, P., Kuang, R., Zeng, L., Xie, Y., 2022
A reference single-cell regulomic and transcriptomic map of cynomolgus monkeys, Qu J, Yang F, Zhu T, Wang Y, Fang W, Ding Y, Zhao X, Qi X, Xie Q, Chen M, Xu Q, Xie Y, Sun Y, Chen D., 2022
Miconazole Exerts Disease-Modifying Effects during Epilepsy by Suppressing Neuroinflammation via NF-ΚB Pathway and INOS Production, Lifen Gong, Tao Zhu, Chen Chen, Ningxiao Xia, Yinping Yao, Junchao Ding, Peng Xu, Shufen Li, Zengxian Sun, Xinyan Dong, Weida Shen, Peng Sun, Linghui Zeng, Yicheng Xie, and Peifang Jiang., 2022
TRPM2 contributes to neuroinflammation and cognitive deficits in a cuprizone-induced multiple sclerosis model via NLRP3 inflammasome, Shao, Y., Chen, C., Zhu, T., Sun, Z., Li, S., Gong, L., Dong, X., Shen, W., Zeng, L., Xie, Y., & Jiang, P., 2021
Cedrol from ginger ameliorates rheumatoid arthritis via reducing inflammation and selectively inhibiting JAK3 phosphorylation, Zhang, Y., Shen, J., Zhao, J., Guan, J., Wei, X., Miao, D., Li, W., Xie, Y., & Zhao, Y., 2021
Intrauterine hyperglycemia induces liver inflammation in mouse male offspring, Dong, X., Lin, D., Sheng, J., Xie, Y., 2021
RNA sequencing analysis of cortex and hippocampus in a kainic acid rat model of temporal lobe epilepsy to identify mechanisms and therapeutic targets related to inflammation, immunity and cognition, Dong, X., Hao, X., Xu, P., Fan, M., Wang, X., Huang, X., Jiang, P., Zeng, L., Xie, Y., 2020
Transient receptor potential melastatin 2 contributes to neuroinflammation and negatively regulates cognitive outcomes in a pilocarpine-induced mouse model of epilepsy, Hu, H., Zhu, T., Gong, L., Zhao, Y., Shao, Y., Li, S., Sun, Z., Ling, Y., Tao, Y., Ying, Y., Lan, C., Xie, Y., Jiang, P., 2020
Diplatin, a Novel and Low-Toxicity Anti-Lung Cancer Platinum Complex, Activation of Cell Death in Tumors via a ROS/JNK/p53-Dependent Pathway, and a Low Rate of Acquired Treatment Resistance, Lin, X., Jia, Y., Dong, X., Shen, J., Jin, Y., Li, Y., Wang, F., Anenberg, E., Zhou, J., Zhu, J., Chen, X., Xie, Q. & Xie, Y., 2019
A negative regulator of synaptic development: MDGA and its links to neurodevelopmental disorders, Wang, R., Dong, J., Wang, L., Dong, X., Anenberg, E., Jiang, P., Zeng, L. & Xie, Y., 2019
Pumping the brakes: suppression of synapse development by MDGA – neuroligin interactions, Connor, S. A., Elegheert, J., Xie, Y. & Craig, A. M., 2019
Heparan sulfate organizes neuronal synapses through neurexin partnerships, Zhang, P., Lu, H., Peixoto, R. T., Pines, M. K., Ge, Y., Oku, S., Siddiqui, T. J., Xie, Y., Wu, W., Archer-Hartmann, S., Yoshida, K., Tanaka, K. F., Aricescu, A. R., Azadi, P., Gordon, M. D., Sabatini, B. L., Wong, R. O. L. & Craig, A. M., 2018
Cortical functional hyperconnectivity in a mouse model of depression and selective network effects of ketamine, McGirr, A., LeDue, J., Chan, A.W., Xie, Y. and Murphy, T.H., 2017
Mapping cortical mesoscopic networks of single spiking cortical or sub-cortical neurons, Xiao, D., Vanni, M. P., Mitelut, C. C., Chan, A. W., Ledue, J. M., Xie, Y., & Murphy, T. H., 2017
Prolonged deficits in parvalbumin neuron stimulation-evoked network activity despite recovery of dendritic structure and excitability in the somatosensory cortex following global ischemia in mice, Xie, Y., Chen, S., Wu, Y., & Murphy, T. H., 2014
Disruption of IP3R2-mediated Ca2+ signaling pathway in astrocytes ameliorates neuronal death and brain damage while reducing behavioral deficits after focal ischemic stroke, Li, H., Xie, Y., Zhang, N., Yu, Y., Zhang, Q., & Ding, S., 2015
Optogenetic stimulation of GABA neurons can decrease local neuronal activity while increasing cortical blood flow, Anenberg, E., Chan, A. W., Xie, Y., LeDue, J. M., & Murphy, T. H., 2015
Prolonged deficits in parvalbumin neuron stimulation-evoked network activity despite recovery of dendritic structure and excitability in the somatosensory cortex following global ischemia in mice, Xie, Y., Chen, S., Wu, Y., & Murphy, T. H., 2014
Resistance of optogenetically evoked motor function to global ischemia and reperfusion in mouse in vivo, Xie, Y., Chen, S., Anenberg, E., & Murphy, T. H., 2013
Dendritic spines and pre-synaptic boutons are stable despite local deep hypothermic challenge and re-warming in vivo, Xie, Y., Chen, S., & Murphy, T., 2012
Optogenetic analysis of neuronal excitability during global ischemia reveals selective deficits in sensory processing following reperfusion in mouse cortex, Chen, S., Mohajerani, M. H., Xie, Y., & Murphy, T. H., 2012
Shp2 plays an important role in acute cigarette smoke-mediated lung inflammation, Li, F.-F., Shen, J., Shen, H.-J., Zhang, X., Cao, R., Zhang, Y., Qui, Q., Lin, X.X., Xie, Y.C., … Ke, Y., 2012
Neuronal protective role of PBEF in a mouse model of cerebral ischemia, Zhang, W., Xie, Y., Wang, T., Bi, J., Li, H., Zhang, L. Q., … Ding, S., 2010
Specific disruption of astrocytic Ca2+ signaling pathway in vivo by adeno-associated viral transduction, Xie, Y., Wang, T., Sun, G. Y., & Ding, S., 2010
Area of Focus
Genetics | Population | Complex Diseases | Health Data | Computational Biology | Human Genome | Biomedical | Research | Genomics | Bioinformatics
