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Rongqing Aaron Pan
Medical School
Zhejiang University
Zhejiang
Language: English, Chinese
Tumor Immunology
Immunotherapy
Nk Cells
T Cells
Mitochondrial Apoptosis
Pyroptosis
Immunogenic Cell Death
Targeted Therapy
Cancer Resistance
Clinical Trials
Areas of Focus
- Tumor Immunology and Immunotherapy
- NK & T Cell Therapy
- Mitochondrial Apoptosis, Pyroptosis, Immunogenic Cell Death
- Combined Immunotherapy and Targeted Therapy
Work Experience
- Research Fellow at Dana-Farber Cancer Institute, Harvard Medical School
- Chief Researcher at Zhejiang University School of Medicine
Academic Background & Achievements
- Graduated from MD Anderson Cancer Center, University of Texas
- Conducted collaborative research at Harvard Medical School's Dana-Farber Cancer Institute
- Published in top journals like Cell, Cancer Cell, and Cancer Discovery
Publications
- Augmenting NK cell-Based Immunotherapy by Targeting Mitochondrial Apoptosis, Pan R, Ryan J, Pan D, Wucherpfennig K, Letai A, 2023
- Synthetic Lethality of Combined BCL-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy, Pan R, Vivian R, Mu H, Andreeff M, 2023
- Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia, Pan R, Hogdal L, Benito J, Konopleva M, Letai A, 2023
- Inhibition of MCL-1 with the pan-BCL-2 family inhibitor (-)BI97D6 overcomes ABT-737 resistance in acute myeloid leukemia, Pan R, Vivian R, Wei J, Konopleva M, Andreeff M, 2023
- Dynamic BH3 Profiling as a Pharmacodynamic Biomarker for the Activity of BH3 Mimetic Compounds, Pan R, Wang Y, Ensar M, Ryan J, Letai A, 2023
- Sequential deletion of Pichia pastoris genes by a self-excisable cassette, Pan R, Zhang J, Shen WL, 2023
- Demethylation and upregulation of an oncogene post hypomethylating treatment, Yao-Chung Liu, Pan R, Li Chai, 2023
- Disruption of Wnt/beta-Catenin Exerts Antileukemia Activity and Synergizes with FLT3 Inhibition in FLT3-Mutant Acute Myeloid Leukemia, Jiang X, Pan R, Carter B, 2023
- Antileukemia Efficacy and Mechanisms of Action of SL-101, a Novel Anti-CD123 Antibody Conjugate, in Acute Myeloid Leukemia, Han L, Pan R, Konopleva M, 2023
- Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia, Qi Zhang, Pan R, Konopleva M, 2023
Awards
- 2023: Zhejiang University School of Medicine Outstanding Talent Award
- 2022: Harvard Life Sciences Distinguished Chinese Scholar Award
- 2021: The Most Impactful Papers at Cancer Discovery 10th Anniversary
- 2020: Abstract Achievement Award at American Society of Hematology Annual Conference
- 2017: Alfred G. Knudson, Jr. Best Dissertation Award (Finalist, 2nd place)
- 2016: Lasher and Longoria Graduate Student Research Award in Cancer Biology
- 2015: Presidents’ Research Scholarship
- 2015: AAAS/Science Program for Excellence in Science
- 2015: Andrew Sowell-Wade Huggins Endowed Scholarship
- 2014: Chinese Government Award for Outstanding Students Abroad
