Professor | Rongqing Aaron Pan | Asia Growth Partners

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Name	Rongqing Aaron Pan
Contact Information	rpan@zju.edu.cn
Language ability	English, Chinese
Province	Zhejiang

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Name

Rongqing Aaron Pan

Contact Information

rpan@zju.edu.cn

Language ability

English, Chinese

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Medical
Academic Background & Achievements	Graduated from MD Anderson Cancer Center, University of Texas Conducted collaborative research at Harvard Medical School's Dana-Farber Cancer Institute Published in top journals like Cell, Cancer Cell, and Cancer Discovery
Work Experience	Research Fellow at Dana-Farber Cancer Institute, Harvard Medical School Chief Researcher at Zhejiang University School of Medicine
Awards	2023: Zhejiang University School of Medicine Outstanding Talent Award 2022: Harvard Life Sciences Distinguished Chinese Scholar Award 2021: The Most Impactful Papers at Cancer Discovery 10th Anniversary 2020: Abstract Achievement Award at American Society of Hematology Annual Conference 2017: Alfred G. Knudson, Jr. Best Dissertation Award (Finalist, 2nd place) 2016: Lasher and Longoria Graduate Student Research Award in Cancer Biology 2015: Presidents’ Research Scholarship 2015: AAAS/Science Program for Excellence in Science 2015: Andrew Sowell-Wade Huggins Endowed Scholarship 2014: Chinese Government Award for Outstanding Students Abroad

University/Lab Affiliation and Title

Zhejiang University

Faculty

Medical

Academic Background & Achievements

Graduated from MD Anderson Cancer Center, University of Texas
Conducted collaborative research at Harvard Medical School's Dana-Farber Cancer Institute
Published in top journals like Cell, Cancer Cell, and Cancer Discovery

Work Experience

Research Fellow at Dana-Farber Cancer Institute, Harvard Medical School
Chief Researcher at Zhejiang University School of Medicine

Awards

2023: Zhejiang University School of Medicine Outstanding Talent Award
2022: Harvard Life Sciences Distinguished Chinese Scholar Award
2021: The Most Impactful Papers at Cancer Discovery 10th Anniversary
2020: Abstract Achievement Award at American Society of Hematology Annual Conference
2017: Alfred G. Knudson, Jr. Best Dissertation Award (Finalist, 2nd place)
2016: Lasher and Longoria Graduate Student Research Award in Cancer Biology
2015: Presidents’ Research Scholarship
2015: AAAS/Science Program for Excellence in Science
2015: Andrew Sowell-Wade Huggins Endowed Scholarship
2014: Chinese Government Award for Outstanding Students Abroad

Areas of Focus	Tumor Immunology and Immunotherapy NK & T Cell Therapy Mitochondrial Apoptosis, Pyroptosis, Immunogenic Cell Death Combined Immunotherapy and Targeted Therapy
Publications	Augmenting NK cell-Based Immunotherapy by Targeting Mitochondrial Apoptosis, Pan R, Ryan J, Pan D, Wucherpfennig K, Letai A, 2023 Synthetic Lethality of Combined BCL-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy, Pan R, Vivian R, Mu H, Andreeff M, 2023 Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia, Pan R, Hogdal L, Benito J, Konopleva M, Letai A, 2023 Inhibition of MCL-1 with the pan-BCL-2 family inhibitor (-)BI97D6 overcomes ABT-737 resistance in acute myeloid leukemia, Pan R, Vivian R, Wei J, Konopleva M, Andreeff M, 2023 Dynamic BH3 Profiling as a Pharmacodynamic Biomarker for the Activity of BH3 Mimetic Compounds, Pan R, Wang Y, Ensar M, Ryan J, Letai A, 2023 Sequential deletion of Pichia pastoris genes by a self-excisable cassette, Pan R, Zhang J, Shen WL, 2023 Demethylation and upregulation of an oncogene post hypomethylating treatment, Yao-Chung Liu, Pan R, Li Chai, 2023 Disruption of Wnt/beta-Catenin Exerts Antileukemia Activity and Synergizes with FLT3 Inhibition in FLT3-Mutant Acute Myeloid Leukemia, Jiang X, Pan R, Carter B, 2023 Antileukemia Efficacy and Mechanisms of Action of SL-101, a Novel Anti-CD123 Antibody Conjugate, in Acute Myeloid Leukemia, Han L, Pan R, Konopleva M, 2023 Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia, Qi Zhang, Pan R, Konopleva M, 2023

Areas of Focus

Tumor Immunology and Immunotherapy
NK & T Cell Therapy
Mitochondrial Apoptosis, Pyroptosis, Immunogenic Cell Death
Combined Immunotherapy and Targeted Therapy

Publications

Augmenting NK cell-Based Immunotherapy by Targeting Mitochondrial Apoptosis, Pan R, Ryan J, Pan D, Wucherpfennig K, Letai A, 2023
Synthetic Lethality of Combined BCL-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy, Pan R, Vivian R, Mu H, Andreeff M, 2023
Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia, Pan R, Hogdal L, Benito J, Konopleva M, Letai A, 2023
Inhibition of MCL-1 with the pan-BCL-2 family inhibitor (-)BI97D6 overcomes ABT-737 resistance in acute myeloid leukemia, Pan R, Vivian R, Wei J, Konopleva M, Andreeff M, 2023
Dynamic BH3 Profiling as a Pharmacodynamic Biomarker for the Activity of BH3 Mimetic Compounds, Pan R, Wang Y, Ensar M, Ryan J, Letai A, 2023
Sequential deletion of Pichia pastoris genes by a self-excisable cassette, Pan R, Zhang J, Shen WL, 2023
Demethylation and upregulation of an oncogene post hypomethylating treatment, Yao-Chung Liu, Pan R, Li Chai, 2023
Disruption of Wnt/beta-Catenin Exerts Antileukemia Activity and Synergizes with FLT3 Inhibition in FLT3-Mutant Acute Myeloid Leukemia, Jiang X, Pan R, Carter B, 2023
Antileukemia Efficacy and Mechanisms of Action of SL-101, a Novel Anti-CD123 Antibody Conjugate, in Acute Myeloid Leukemia, Han L, Pan R, Konopleva M, 2023
Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia, Qi Zhang, Pan R, Konopleva M, 2023

Tumor Immunology Immunotherapy Nk Cells T Cells Mitochondrial Apoptosis Pyroptosis Immunogenic Cell Death Targeted Therapy Cancer Resistance Clinical Trials

Qi Zhang - Zhejiang University

Xia Dajing - Zhejiang University

Yunhua Liu - Zhejiang University

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