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Xian Wang
wangx118@zju.edu.cn
Chinese, German, English
Zhejiang
Zhejiang University
Medical
  • 1989-1996 Clinical Medicine: Zhejiang Medical University
  • 1996-2002 Second Affiliated Hospital, Zhejiang University School of Medicine
  • 2002-2005 PhD: Karlsruhe University, Germany
  • 2005-2007 Oncology Center: Chinese University of Hong Kong
  • 2007-2009 City University of Hong Kong
  • 2009-present Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
  • 1996-2002 - Second Affiliated Hospital, Zhejiang University School of Medicine - Role not specified
  • 2005-2007 - Oncology Center, Chinese University of Hong Kong - Role not specified
  • 2007-2009 - City University of Hong Kong - Role not specified
  • 2009-present - Sir Run Run Shaw Hospital, Zhejiang University School of Medicine - Role not specified
Mechanisms and intervention strategies of malignant tumor development
  • The epigenetic aspect of gastric carcinoma, Wang X and Jin H, 2011
  • Circulating methylated DNA as biomarkers of cancer detection, Jin H, Ma Y, Shen Q and Wang X, 2012
  • β-catenin represses miR455-3p to stimulate m6A modification of HSF1 mRNA and promote its translation in colorectal cancer, Song P, Feng L, Li, J, Dai D, Zhu L, Wang C, Li J, Ling L, Zhou Q, Shi R, Wang X and Jin H, 2020
  • SIRT1 deacetylated and stabilized XRCC1 to promote chemoresistance in lung cancer, Yousafzai NA, Zhou Q, Xu W, Shi Q, Xu J, Feng L, Chen H, Shin VY, Jin H, Wang X, 2019
  • Overexpressed pseudogenes, DUXAP8 and DUXAP9, promote growth of renal cell carcinoma and serve as unfavorable prognostic biomarkers, Chen J, Lou W, Ding B, Wang X, 2019
  • A significant response to a combination of trastuzumab and vinorelbine in HER2-negative metastatic breast cancer with HER2 V777L mutation, Lei L, Ye WW, Zheng LF, Huang P, Shi L, Huang J, Zheng YB, Chen ZH, Wang XJ, Wang X, 2019
  • Heat Shock Factor 1 Epigenetically Stimulates Glutaminase-1-Dependent mTOR Activation to Promote Colorectal Carcinogenesis, Li J, Song P, Jiang T, Dai D, Wang H, Sun J, Zhu L, Xu W, Feng L, Shin VY, Morrison H, Wang X, Jin H, 2018
  • N6-methyladenosine links RNA metabolism to cancer progression, Dai D, Wang H, Zhu L, Jin H, Wang X, 2018
  • YY1-miR372-SQSTM1 regulatory axis in autophagy, Feng L, Ma Y, Sun J, Shen Q, Liu L, Lu H, Wang F, Yue Y, Li J, Zhang S, Lin X, Chu J, Han W, Wang X, Jin H, 2014
  • New tumor suppressor CXXC finger protein 4 inactivates mitogen activated protein kinase signaling, Lu H, Jin W, Sun J, Feng L, Lan H, Shen Q, Ma Y, Li J, Yue Y, Jin H, Wang X, 2014
  • Increased Circulating MicroRNA-155 as a Potential Biomarker for Breast Cancer Screening: A Meta-Analysis, Wang F, Hou J, Jin W, Li J, Yue Y, Jin H, Wang X, 2014
  • Down-regulation of Histone Deacetylase 1 by microRNA-520h contributes to the chemotherapeutic effect of doxorubicin, Shen Q, Yao Q, Sun J, Feng L, Lu H, Ma Y, Liu L, Yue Y, Li J, Wang F, Jin H, Wang X, 2014
  • Regulation and function of mitophagy in development and cancer, Lu H, Li G, Liu L, Feng L, Wang X and Jin H, 2013
  • Enhancer of zeste homologue 2 activates wnt signaling through downregulating CXXC finger protein 4, Lu H, Sun J, Wang F, Feng L, Ma Y, Shen Q, Jiang Z, Sun X, Wang X, Jin H, 2013
  • Histone deacetylase 3 inhibits expression of PUMA in gastric cancer cells, Feng L, Pan M, Sun J, Lu H, Shen Q, Zhang S, Jiang T, Liu L, Jin W, Chen Y, Wang X, Jin H, 2013
  • The epigenetic basis of Warburg effect, Wang X and Jin H, 2010
  • Warburg effect revisited: An epigenetic link between glycolysis and gastric carcinogenesis, Liu X, Wang X, Zhang J, Lam EK, Shin VY, Cheng AS, Yu J, Chan FK, Sung JJ and Jin HC, 2010
  • CHD5 is down-regulated through promoter hypermethylation in gastric cancer, Wang X, Lau KK, So LK and Lam YW, 2009
  • Epigenetic identification of ADAMTS18 as a novel 16q23.1 tumor suppressor frequently silenced in esophageal, nasopharyngeal and multiple other carcinomas, Jin H, Wang X, Wong AHY, Chan ATC, Tao Q, 2007
  • Protein kinase CK2 phosphorylates Sec63p to stimulate the assembly of the endoplasmic reticulum protein translocation apparatus, Wang X and Johnsson N, 2005
  • Impaired autophagic degradation of lncRNA ARHGAP5-AS1 promotes chemoresistance in gastric cancer, Zhu L, Zhu Y, Han S, Chen M, Song P, Dai D, Xu W, Jiang T, Feng L, Shin VY, Wang X, Jin H, 2019
  • Long non-coding RNA NEAT1 confers oncogenic role in triple-negative breast cancer through modulating chemoresistance and cancer stemness, Shin VY, Chen J, Cheuk IW, Siu MT, Ho CW, Wang X, Jin H, Kwong A, 2019
  • Metabolic enzyme PDK3 forms a positive feedback loop with transcription factor HSF1 to drive chemoresistance, Xu J, Shi Q, Xu W, Zhou Q, Shi R, Ma Y, Chen D, Zhu L, Feng L, Cheng AS, Morrison H, Wang X, Jin H, 2019
  • CD69 enhances immunosuppressive function of regulatory T cells and attenuates colitis by prompting IL-10 production, Yu L, Yang F, Zhang F, Guo D, Li L, Wang X, Liang T, Wang J, Cai Z, Jin H, 2018
  • Tamoxifen activates Nrf2-dependent SQSTM1 transcription to promote endometrial hyperplasia, Feng L, Li J, Yang L, Zhu L, Huang X, Zhang S, Luo L, Jiang Z, Jiang T, Xu W, Wang X, Jin H, 2017
  • COPS5 Amplification and Overexpression Confers Endocrine Resistance in ER-positive Breast Cancer by Degradation of NCoR Protein, Lu R, Hu X, Xu G, Zhou J, Zhu A, Gao X, Wang X, Jin H, Zhu P, Guo L, 2016
  • Novel nucleolar isolation method reveals rapid response of human nucleolar proteomes to serum stimulation, Liang Y, Wang X, So K, Lam Y and Li Z, 2012
  • Homeobox D10 gene, a candidate tumor suppressor, is downregulated through promoter hypermethylation and associated with gastric carcinogenesis, Wang L, Chen S, Xue M, Zhong J, Wang X, Gan L, Lam E, Liu X, Zhang J, Zhou T, Yu J, Jin H and Si J, 2012
  • Yin Yang-1 suppresses differentiation of hepatocellular carcinoma cells through the downregulation of CCAAT/enhancer-binding protein alpha, Zhang S, Jiang T, Feng L, Sun J, Lu H, Wang Q, Pan M, Huang D, Wang X, Wang L and Jin H, 2012
  • The tumor suppressor UCHL1 forms a complex with p53/MDM2/ARF to promote p53 signaling, and is frequently silenced in nasopharyngeal carcinoma, Li L, Tao Q, Jin H, Hasselt AV, Poon FF, Wang X, Zeng MS, Jia W, Zeng YX, Chan AT, Cao Y, 2010
  • Epigenetic disruption of interferon-gamma response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas, Lee KY, Geng H, Ng KM, Yu J, van Hasselt A, Cao Y, Zeng YX, Wong AH, Wang X, 2008
  • Epigenetic identification of ubiquitin carboxyl-terminal hydrolase L1 as a functional tumor suppressor and biomarker for hepatocellular carcinoma and other digestive tumors, Yu J, Tao Q, Cheung K, Jin H, Poon FF, Wang X, 2008
  • Epigenetic silencing of a Ca(2+)-regulated Ras GTPase-activating protein RASAL defines a new mechanism of Ras activation in human cancers, Jin H, Wang X, Wong AHY, Chan ATC, Cullen P, Tao Q, 2007
Malignant Tumors Mechanisms Intervention Strategies Cancer Oncology Tumor Development Biomedical Research Genetics Epigenetics Clinical Research

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