1989-1996 Clinical Medicine: Zhejiang Medical University
1996-2002 Second Affiliated Hospital, Zhejiang University School of Medicine
2002-2005 PhD: Karlsruhe University, Germany
2005-2007 Oncology Center: Chinese University of Hong Kong
2007-2009 City University of Hong Kong
2009-present Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
1996-2002 - Second Affiliated Hospital, Zhejiang University School of Medicine - Role not specified
2005-2007 - Oncology Center, Chinese University of Hong Kong - Role not specified
2007-2009 - City University of Hong Kong - Role not specified
2009-present - Sir Run Run Shaw Hospital, Zhejiang University School of Medicine - Role not specified
Research
Mechanisms and intervention strategies of malignant tumor development
The epigenetic aspect of gastric carcinoma, Wang X and Jin H, 2011
Circulating methylated DNA as biomarkers of cancer detection, Jin H, Ma Y, Shen Q and Wang X, 2012
β-catenin represses miR455-3p to stimulate m6A modification of HSF1 mRNA and promote its translation in colorectal cancer, Song P, Feng L, Li, J, Dai D, Zhu L, Wang C, Li J, Ling L, Zhou Q, Shi R, Wang X and Jin H, 2020
SIRT1 deacetylated and stabilized XRCC1 to promote chemoresistance in lung cancer, Yousafzai NA, Zhou Q, Xu W, Shi Q, Xu J, Feng L, Chen H, Shin VY, Jin H, Wang X, 2019
Overexpressed pseudogenes, DUXAP8 and DUXAP9, promote growth of renal cell carcinoma and serve as unfavorable prognostic biomarkers, Chen J, Lou W, Ding B, Wang X, 2019
A significant response to a combination of trastuzumab and vinorelbine in HER2-negative metastatic breast cancer with HER2 V777L mutation, Lei L, Ye WW, Zheng LF, Huang P, Shi L, Huang J, Zheng YB, Chen ZH, Wang XJ, Wang X, 2019
Heat Shock Factor 1 Epigenetically Stimulates Glutaminase-1-Dependent mTOR Activation to Promote Colorectal Carcinogenesis, Li J, Song P, Jiang T, Dai D, Wang H, Sun J, Zhu L, Xu W, Feng L, Shin VY, Morrison H, Wang X, Jin H, 2018
N6-methyladenosine links RNA metabolism to cancer progression, Dai D, Wang H, Zhu L, Jin H, Wang X, 2018
YY1-miR372-SQSTM1 regulatory axis in autophagy, Feng L, Ma Y, Sun J, Shen Q, Liu L, Lu H, Wang F, Yue Y, Li J, Zhang S, Lin X, Chu J, Han W, Wang X, Jin H, 2014
New tumor suppressor CXXC finger protein 4 inactivates mitogen activated protein kinase signaling, Lu H, Jin W, Sun J, Feng L, Lan H, Shen Q, Ma Y, Li J, Yue Y, Jin H, Wang X, 2014
Increased Circulating MicroRNA-155 as a Potential Biomarker for Breast Cancer Screening: A Meta-Analysis, Wang F, Hou J, Jin W, Li J, Yue Y, Jin H, Wang X, 2014
Down-regulation of Histone Deacetylase 1 by microRNA-520h contributes to the chemotherapeutic effect of doxorubicin, Shen Q, Yao Q, Sun J, Feng L, Lu H, Ma Y, Liu L, Yue Y, Li J, Wang F, Jin H, Wang X, 2014
Regulation and function of mitophagy in development and cancer, Lu H, Li G, Liu L, Feng L, Wang X and Jin H, 2013
Enhancer of zeste homologue 2 activates wnt signaling through downregulating CXXC finger protein 4, Lu H, Sun J, Wang F, Feng L, Ma Y, Shen Q, Jiang Z, Sun X, Wang X, Jin H, 2013
Histone deacetylase 3 inhibits expression of PUMA in gastric cancer cells, Feng L, Pan M, Sun J, Lu H, Shen Q, Zhang S, Jiang T, Liu L, Jin W, Chen Y, Wang X, Jin H, 2013
The epigenetic basis of Warburg effect, Wang X and Jin H, 2010
Warburg effect revisited: An epigenetic link between glycolysis and gastric carcinogenesis, Liu X, Wang X, Zhang J, Lam EK, Shin VY, Cheng AS, Yu J, Chan FK, Sung JJ and Jin HC, 2010
CHD5 is down-regulated through promoter hypermethylation in gastric cancer, Wang X, Lau KK, So LK and Lam YW, 2009
Epigenetic identification of ADAMTS18 as a novel 16q23.1 tumor suppressor frequently silenced in esophageal, nasopharyngeal and multiple other carcinomas, Jin H, Wang X, Wong AHY, Chan ATC, Tao Q, 2007
Protein kinase CK2 phosphorylates Sec63p to stimulate the assembly of the endoplasmic reticulum protein translocation apparatus, Wang X and Johnsson N, 2005
Impaired autophagic degradation of lncRNA ARHGAP5-AS1 promotes chemoresistance in gastric cancer, Zhu L, Zhu Y, Han S, Chen M, Song P, Dai D, Xu W, Jiang T, Feng L, Shin VY, Wang X, Jin H, 2019
Long non-coding RNA NEAT1 confers oncogenic role in triple-negative breast cancer through modulating chemoresistance and cancer stemness, Shin VY, Chen J, Cheuk IW, Siu MT, Ho CW, Wang X, Jin H, Kwong A, 2019
Metabolic enzyme PDK3 forms a positive feedback loop with transcription factor HSF1 to drive chemoresistance, Xu J, Shi Q, Xu W, Zhou Q, Shi R, Ma Y, Chen D, Zhu L, Feng L, Cheng AS, Morrison H, Wang X, Jin H, 2019
CD69 enhances immunosuppressive function of regulatory T cells and attenuates colitis by prompting IL-10 production, Yu L, Yang F, Zhang F, Guo D, Li L, Wang X, Liang T, Wang J, Cai Z, Jin H, 2018
Tamoxifen activates Nrf2-dependent SQSTM1 transcription to promote endometrial hyperplasia, Feng L, Li J, Yang L, Zhu L, Huang X, Zhang S, Luo L, Jiang Z, Jiang T, Xu W, Wang X, Jin H, 2017
COPS5 Amplification and Overexpression Confers Endocrine Resistance in ER-positive Breast Cancer by Degradation of NCoR Protein, Lu R, Hu X, Xu G, Zhou J, Zhu A, Gao X, Wang X, Jin H, Zhu P, Guo L, 2016
Novel nucleolar isolation method reveals rapid response of human nucleolar proteomes to serum stimulation, Liang Y, Wang X, So K, Lam Y and Li Z, 2012
Homeobox D10 gene, a candidate tumor suppressor, is downregulated through promoter hypermethylation and associated with gastric carcinogenesis, Wang L, Chen S, Xue M, Zhong J, Wang X, Gan L, Lam E, Liu X, Zhang J, Zhou T, Yu J, Jin H and Si J, 2012
Yin Yang-1 suppresses differentiation of hepatocellular carcinoma cells through the downregulation of CCAAT/enhancer-binding protein alpha, Zhang S, Jiang T, Feng L, Sun J, Lu H, Wang Q, Pan M, Huang D, Wang X, Wang L and Jin H, 2012
The tumor suppressor UCHL1 forms a complex with p53/MDM2/ARF to promote p53 signaling, and is frequently silenced in nasopharyngeal carcinoma, Li L, Tao Q, Jin H, Hasselt AV, Poon FF, Wang X, Zeng MS, Jia W, Zeng YX, Chan AT, Cao Y, 2010
Epigenetic disruption of interferon-gamma response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas, Lee KY, Geng H, Ng KM, Yu J, van Hasselt A, Cao Y, Zeng YX, Wong AH, Wang X, 2008
Epigenetic identification of ubiquitin carboxyl-terminal hydrolase L1 as a functional tumor suppressor and biomarker for hepatocellular carcinoma and other digestive tumors, Yu J, Tao Q, Cheung K, Jin H, Poon FF, Wang X, 2008
Epigenetic silencing of a Ca(2+)-regulated Ras GTPase-activating protein RASAL defines a new mechanism of Ras activation in human cancers, Jin H, Wang X, Wong AHY, Chan ATC, Cullen P, Tao Q, 2007
Keywords
Malignant TumorsMechanismsIntervention StrategiesCancerOncologyTumor DevelopmentBiomedical ResearchGeneticsEpigeneticsClinical Research