Professor | Junnan Wu | Asia Growth Partners

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Name	Junnan Wu
Contact Information	junnan.wu@zju.edu.cn
Language ability	Chinese, English
Province	Zhejiang

Upload Avatar (500 x 500)

Name

Junnan Wu

Contact Information

junnan.wu@zju.edu.cn

Language ability

Chinese, English

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Medical
Academic Background & Achievements	2005-2010 Bachelor's Degree: Southern Medical University 2010-2015 Master's and Doctoral Degree: Nanjing University Medical School 2019-2021 Postdoctoral Research: University of Pennsylvania Medical School Zhejiang University 'Clinical Hundred Talents Program' Researcher Published over 20 SCI papers in journals like Immunity, JCI, JASN
Work Experience	2015-2021 - Shanghai Sixth People's Hospital - Nephrology Department 2022-present - Zhejiang University School of Medicine, Sir Run Run Shaw Hospital - Nephrology Department
Awards	Shanghai Medical Science and Technology Award (2017): Second Prize, Rank 7/12 Jiangsu Province Science and Technology Award (2017): First Prize, Rank 5/10 Chinese Society of Integrative Medicine Science and Technology Award (2017): First Prize, Rank 12/15 Nominated for Shanghai Jiao Tong University School of Medicine 'Jiulong Medical Young Talent Award' (2019) Shanghai Health Commission 'Medical Star' (2018) Shanghai 'Young Nephrology Researcher' (2018)

University/Lab Affiliation and Title

Zhejiang University

Faculty

Medical

Academic Background & Achievements

2005-2010 Bachelor's Degree: Southern Medical University
2010-2015 Master's and Doctoral Degree: Nanjing University Medical School
2019-2021 Postdoctoral Research: University of Pennsylvania Medical School
Zhejiang University 'Clinical Hundred Talents Program' Researcher
Published over 20 SCI papers in journals like Immunity, JCI, JASN

Work Experience

2015-2021 - Shanghai Sixth People's Hospital - Nephrology Department
2022-present - Zhejiang University School of Medicine, Sir Run Run Shaw Hospital - Nephrology Department

Awards

Shanghai Medical Science and Technology Award (2017): Second Prize, Rank 7/12
Jiangsu Province Science and Technology Award (2017): First Prize, Rank 5/10
Chinese Society of Integrative Medicine Science and Technology Award (2017): First Prize, Rank 12/15
Nominated for Shanghai Jiao Tong University School of Medicine 'Jiulong Medical Young Talent Award' (2019)
Shanghai Health Commission 'Medical Star' (2018)
Shanghai 'Young Nephrology Researcher' (2018)

Areas of Focus	Research on the physiological and pathological mechanisms of renal podocytes Clinical research on risk factors related to peritoneal dialysis
Publications	APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis, Junnan Wu, Ziyuan Ma, Archana Raman, Pazit Beckerman, Poonam Dhillon, Dhanunjay Mukhi, Matthew Palmer, Hua Chang Chen, Cassiane Robinson Cohen, Thomas Dunn, John Reilly, Nuala Meyer, Michael Shahaty, Zoltan Arany, György Haskó, Krzysztof Laudanski, Adriana Hung, Katalin Susztak, 2021 The key role of NLRP3 and STING in APOL1-associated podocytopathy, Junnan Wu, Archana Raman, Nathan J. Coffey, Xin Sheng, Joseph Wahba, Matthew J. Seasock, Ziyuan Ma, Pazit Beckerman, Dorottya Laczko, Matthew B. Palmer, Jeffrey B. Kopp, Jay J. Kuo, Steven S. Pullen, Carine Boustany-Kari, Andreas Linkermann, and Katalin Susztak, 2021 MicroRNA-30 family members regulate calcium/calcineurin signaling in podocytes, Junnan Wu, Chunxia Zheng, Xiao Wang, Yue Zhao, Changming Zhang, Lin Liu, Yuqiu Lu, Weisong Qin, Shaolin Shi, and Zhihong Liu, 2015 Downregulation of MicroRNA-30 Facilitates Podocyte Injury and Is Prevented by Glucocorticoids, Junnan Wu, Chunxia Zheng, Yun Fan, Caihong Zeng, Zhaohong Chen, Weisong Qin, Changming Zhang, Wanfen Zhang, Xiao Wang, Xiaodong Zhu, Mingchao Zhang, Ke Zen, and Zhihong Liu, 2014 Angiotensin II induces calcium/calcineurin signaling and podocyte injury by downregulating microRNA-30 family members, Yue Zhao, Junnan Wu, Mingchao Zhang, Minlin Zhou, Feng Xu, Xiaodong Zhu, Xianguang Zhou, Yue Lang, Fan Yang, Shifeng Yun, Shaolin Shi and Zhihong Liu, 2017 Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments, Xin Sheng, Yuting Guan, Ziyuan Ma, Junnan Wu, Hongbo Liu, Chengxiang Qiu, Steven Vitale, Zhen Miao, Matthew J. Seasock, Matthew Palmer, Myung K. Shin, Kevin L. Duffin, Steven S. Pullen, Todd L. Edwards, Jacklyn N. Hellwege, Adriana M. Hung, Mingyao Li, Benjamin F. Voight, Thomas M. Coffman, Christopher D. Brown & Katalin Susztak, 2021 Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets, Zhen Miao, Michael S Balzer, Ziyuan Ma, Hongbo Liu, Junnan Wu, Rojesh Shrestha, Tamas Aranyi, Amy Kwan, Ayano Kondo, Marco Pontoglio, Junhyong Kim, Mingyao Li, Klaus H Kaestner, Katalin Susztak, 2021 Transcriptome-wide association analysis identifies DACH1 as a kidney disease risk gene that contributes to fibrosis, Tomohito Doke, Shizheng Huang, Chengxiang Qiu, Hongbo Liu, Yuting Guan, Hailong Hu, Ziyuan Ma, Junnan Wu, Zhen Miao, Xin Sheng, Jianfu Zhou, Aili Cao, Jianhua Li, Lewis Kaufman, Adriana Hung, Christopher D Brown, Richard Pestell, Katalin Susztak, 2021 Podocyte autophagic activity plays a protective role in renal injury and delays the progression of podocytopathies, Caihong Zeng, Yun Fan, Junnan Wu, Shaolin Shi, Zhaohong Chen, Yongzhong Zhong, Changming Zhang, Ke Zen, Zhihong Liu, 2014 MiR-30 family prevents uPAR-ITGB3 signaling activation through calcineurin-NFATC pathway to protect podocytes, Yue Lang, Yue Zhao, Chunxia Zheng, Yinghui Lu, Junnan Wu, Xiaodong Zhu, Mingchao Zhang, Fan Yang, Xiaodong Xu, Shaolin Shi, Zhihong Liu, 2019 Plasma microRNA-186 and proteinuria in focal segmental glomerulosclerosis, Changming Zhang, Wanfen Zhang, Hui-Mei Chen, Chunbei Liu, Junnan Wu, Shaolin Shi, Zhi-Hong Liu, 2015 Nicotinamide retains Klotho expression and ameliorates rhabdomyolysis-induced acute kidney injury, Wenjun Lin, Xianfeng Wu, Jiejun Wen, Yang Fei, Junnan Wu, Xiaomei Li, Qunzi Zhang, Yang Dong, Tao Xu, Ying Fan, Niansong Wang, 2021 Creatine Kinase and Mortality in Peritoneal Dialysis, Xianfeng Wu, Lei Zhou, Xiaojiang Zhan, Yueqiang Wen, Xiaoyang Wang, Xiaoran Feng, Niansong Wang, Fenfen Peng, Junnan Wu, 2022 Albumin to Total Cholesterol Ratio and Mortality in Peritoneal Dialysis, Xianfeng Wu, Jiao Meng, Lei Zhou, Xiaojiang Zhan, Yueqiang Wen, Xiaoyang Wang, Xiaoran Feng, Niansong Wang, Fenfen Peng, Junnan Wu, 2022 Asymptomatic hyperuricemia and incident congestive heart failure in elderly patients without comorbidities, Xianfeng Wu, Guihua Jian, Yuezhong Tang, Huan Cheng, Niansong Wang, Junnan Wu, 2020 Low-Density Lipoprotein Cholesterol and Mortality in Peritoneal Dialysis, Xianfeng Wu, Lei Zhou, Xiaojiang Zhan, Yueqiang Wen, Xiaoyang Wang, Xiaoran Feng, Niansong Wang, Fenfen Peng, Junnan Wu, 2022 Hyperlipidemia and mortality in patients on peritoneal dialysis, Xiaoran Feng, Xiaojiang Zhan, Yueqiang Wen, FenFen Peng, Xiaoyang Wang, Niansong Wang, Xianfeng Wu, Junnan Wu, 2022 Asymptomatic hyperuricemia and coronary artery disease in elderly patients without comorbidities, Junnan Wu, Guangtao Lei, Xiao Wang, Yuezhong Tang, Huan Cheng, Guihua Jian, Xianfeng Wu and Niansong Wang, 2017 Nicotinamide retains Klotho expression and ameliorates rhabdomyolysis-induced acute kidney injury, Wenjun Lin, Xianfeng Wu, Jiejun Wen, Yang Fei, Junnan Wu, Xiaomei Li, Qunzi Zhang, Yang Dong, Tao Xu, Ying Fan, Niansong Wang, 2021 Urine Albumin/Creatinine Ratio and Microvascular Disease in Elderly Hypertensive Patients without Comorbidities, Guihua Jian, Wenjun Lin, Niansong Wang, Junnan Wu, Xianfeng Wu, 2021 Unbiased Analysis of Temporal Changes in Immune Serum Markers in Acute COVID-19 Infection With Emphasis on Organ Failure, Anti-Viral Treatment, and Demographic Characteristics, Krzysztof Laudanski, Hajj Jihane, Brook Antalosky, Danyal Ghani, Uyen Phan, Ruth Hernandez, Tony Okeke, Junnan Wu, Daniel Rader, Katalin Susztak, 2021 Longitudinal urinary biomarkers of immunological activation in covid-19 patients without clinically apparent kidney disease versus acute and chronic failure, Krzysztof Laudanski, Tony Okeke, Jihane Hajj, Kumal Siddiq, Daniel J Rader, Junnan Wu, Katalin Susztak, 2021

Areas of Focus

Research on the physiological and pathological mechanisms of renal podocytes
Clinical research on risk factors related to peritoneal dialysis

Publications

APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis, Junnan Wu, Ziyuan Ma, Archana Raman, Pazit Beckerman, Poonam Dhillon, Dhanunjay Mukhi, Matthew Palmer, Hua Chang Chen, Cassiane Robinson Cohen, Thomas Dunn, John Reilly, Nuala Meyer, Michael Shahaty, Zoltan Arany, György Haskó, Krzysztof Laudanski, Adriana Hung, Katalin Susztak, 2021
The key role of NLRP3 and STING in APOL1-associated podocytopathy, Junnan Wu, Archana Raman, Nathan J. Coffey, Xin Sheng, Joseph Wahba, Matthew J. Seasock, Ziyuan Ma, Pazit Beckerman, Dorottya Laczko, Matthew B. Palmer, Jeffrey B. Kopp, Jay J. Kuo, Steven S. Pullen, Carine Boustany-Kari, Andreas Linkermann, and Katalin Susztak, 2021
MicroRNA-30 family members regulate calcium/calcineurin signaling in podocytes, Junnan Wu, Chunxia Zheng, Xiao Wang, Yue Zhao, Changming Zhang, Lin Liu, Yuqiu Lu, Weisong Qin, Shaolin Shi, and Zhihong Liu, 2015
Downregulation of MicroRNA-30 Facilitates Podocyte Injury and Is Prevented by Glucocorticoids, Junnan Wu, Chunxia Zheng, Yun Fan, Caihong Zeng, Zhaohong Chen, Weisong Qin, Changming Zhang, Wanfen Zhang, Xiao Wang, Xiaodong Zhu, Mingchao Zhang, Ke Zen, and Zhihong Liu, 2014
Angiotensin II induces calcium/calcineurin signaling and podocyte injury by downregulating microRNA-30 family members, Yue Zhao*, Junnan Wu*, Mingchao Zhang, Minlin Zhou, Feng Xu, Xiaodong Zhu, Xianguang Zhou, Yue Lang, Fan Yang, Shifeng Yun, Shaolin Shi and Zhihong Liu, 2017
Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments, Xin Sheng, Yuting Guan, Ziyuan Ma, Junnan Wu, Hongbo Liu, Chengxiang Qiu, Steven Vitale, Zhen Miao, Matthew J. Seasock, Matthew Palmer, Myung K. Shin, Kevin L. Duffin, Steven S. Pullen, Todd L. Edwards, Jacklyn N. Hellwege, Adriana M. Hung, Mingyao Li, Benjamin F. Voight, Thomas M. Coffman, Christopher D. Brown & Katalin Susztak, 2021
Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets, Zhen Miao, Michael S Balzer, Ziyuan Ma, Hongbo Liu, Junnan Wu, Rojesh Shrestha, Tamas Aranyi, Amy Kwan, Ayano Kondo, Marco Pontoglio, Junhyong Kim, Mingyao Li, Klaus H Kaestner, Katalin Susztak, 2021
Transcriptome-wide association analysis identifies DACH1 as a kidney disease risk gene that contributes to fibrosis, Tomohito Doke, Shizheng Huang, Chengxiang Qiu, Hongbo Liu, Yuting Guan, Hailong Hu, Ziyuan Ma, Junnan Wu, Zhen Miao, Xin Sheng, Jianfu Zhou, Aili Cao, Jianhua Li, Lewis Kaufman, Adriana Hung, Christopher D Brown, Richard Pestell, Katalin Susztak, 2021
Podocyte autophagic activity plays a protective role in renal injury and delays the progression of podocytopathies, Caihong Zeng, Yun Fan, Junnan Wu, Shaolin Shi, Zhaohong Chen, Yongzhong Zhong, Changming Zhang, Ke Zen, Zhihong Liu, 2014
MiR-30 family prevents uPAR-ITGB3 signaling activation through calcineurin-NFATC pathway to protect podocytes, Yue Lang, Yue Zhao, Chunxia Zheng, Yinghui Lu, Junnan Wu, Xiaodong Zhu, Mingchao Zhang, Fan Yang, Xiaodong Xu, Shaolin Shi, Zhihong Liu, 2019
Plasma microRNA-186 and proteinuria in focal segmental glomerulosclerosis, Changming Zhang, Wanfen Zhang, Hui-Mei Chen, Chunbei Liu, Junnan Wu, Shaolin Shi, Zhi-Hong Liu, 2015
Nicotinamide retains Klotho expression and ameliorates rhabdomyolysis-induced acute kidney injury, Wenjun Lin, Xianfeng Wu, Jiejun Wen, Yang Fei, Junnan Wu, Xiaomei Li, Qunzi Zhang, Yang Dong, Tao Xu, Ying Fan, Niansong Wang, 2021
Creatine Kinase and Mortality in Peritoneal Dialysis, Xianfeng Wu, Lei Zhou, Xiaojiang Zhan, Yueqiang Wen, Xiaoyang Wang, Xiaoran Feng, Niansong Wang, Fenfen Peng, Junnan Wu, 2022
Albumin to Total Cholesterol Ratio and Mortality in Peritoneal Dialysis, Xianfeng Wu, Jiao Meng, Lei Zhou, Xiaojiang Zhan, Yueqiang Wen, Xiaoyang Wang, Xiaoran Feng, Niansong Wang, Fenfen Peng, Junnan Wu, 2022
Asymptomatic hyperuricemia and incident congestive heart failure in elderly patients without comorbidities, Xianfeng Wu, Guihua Jian, Yuezhong Tang, Huan Cheng, Niansong Wang, Junnan Wu, 2020
Low-Density Lipoprotein Cholesterol and Mortality in Peritoneal Dialysis, Xianfeng Wu, Lei Zhou, Xiaojiang Zhan, Yueqiang Wen, Xiaoyang Wang, Xiaoran Feng, Niansong Wang, Fenfen Peng, Junnan Wu, 2022
Hyperlipidemia and mortality in patients on peritoneal dialysis, Xiaoran Feng, Xiaojiang Zhan, Yueqiang Wen, FenFen Peng, Xiaoyang Wang, Niansong Wang, Xianfeng Wu, Junnan Wu, 2022
Asymptomatic hyperuricemia and coronary artery disease in elderly patients without comorbidities, Junnan Wu*, Guangtao Lei*, Xiao Wang, Yuezhong Tang, Huan Cheng, Guihua Jian, Xianfeng Wu and Niansong Wang, 2017
Nicotinamide retains Klotho expression and ameliorates rhabdomyolysis-induced acute kidney injury, Wenjun Lin, Xianfeng Wu, Jiejun Wen, Yang Fei, Junnan Wu, Xiaomei Li, Qunzi Zhang, Yang Dong, Tao Xu, Ying Fan, Niansong Wang, 2021
Urine Albumin/Creatinine Ratio and Microvascular Disease in Elderly Hypertensive Patients without Comorbidities, Guihua Jian, Wenjun Lin, Niansong Wang, Junnan Wu, Xianfeng Wu, 2021
Unbiased Analysis of Temporal Changes in Immune Serum Markers in Acute COVID-19 Infection With Emphasis on Organ Failure, Anti-Viral Treatment, and Demographic Characteristics, Krzysztof Laudanski, Hajj Jihane, Brook Antalosky, Danyal Ghani, Uyen Phan, Ruth Hernandez, Tony Okeke, Junnan Wu, Daniel Rader, Katalin Susztak, 2021
Longitudinal urinary biomarkers of immunological activation in covid-19 patients without clinically apparent kidney disease versus acute and chronic failure, Krzysztof Laudanski, Tony Okeke, Jihane Hajj, Kumal Siddiq, Daniel J Rader, Junnan Wu, Katalin Susztak, 2021

Renal Podocytes Physiological Mechanisms Pathological Mechanisms Peritoneal Dialysis Risk Factors Clinical Research Kidney Disease Podocytopathy Biomarkers Translational Research

Chen Weiyu - Zhejiang University

Naranmandura Hua - Zhejiang University

Huang He - Zhejiang University

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