Professor | Ting Chen | Asia Growth Partners

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Name	Ting Chen
Contact Information	ct010151452@zju.edu.cn
Language ability	Chinese, English
Province	Zhejiang

Upload Avatar (500 x 500)

Name

Ting Chen

Contact Information

ct010151452@zju.edu.cn

Language ability

Chinese, English

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Medical
Academic Background & Achievements	Zhejiang Province Outstanding Youth Fund recipient Chief Scientist of the National Key R&D Program Youth Scientist Project Visiting Scholar at University College London Published over 30 SCI papers with a cumulative impact factor of over 100
Awards	Zhejiang Biomedical Engineering Society Outstanding Scientific Worker Zhejiang University Zheng Shu Scholarship Zhejiang University National Scholarship Gong Lansheng Young Scholar Award Oriental Rising Star Nomination Award Second Prize of Chinese Medical Science and Technology Award Second Prize of Shanghai Medical Science and Technology Award Second Prize of National Higher Education Scientific Research Outstanding Achievement Award First Prize of Zhejiang Province Medical and Health Science and Technology Award

University/Lab Affiliation and Title

Zhejiang University

Faculty

Medical

Academic Background & Achievements

Zhejiang Province Outstanding Youth Fund recipient
Chief Scientist of the National Key R&D Program Youth Scientist Project
Visiting Scholar at University College London
Published over 30 SCI papers with a cumulative impact factor of over 100

Awards

Zhejiang Biomedical Engineering Society Outstanding Scientific Worker
Zhejiang University Zheng Shu Scholarship
Zhejiang University National Scholarship
Gong Lansheng Young Scholar Award
Oriental Rising Star Nomination Award
Second Prize of Chinese Medical Science and Technology Award
Second Prize of Shanghai Medical Science and Technology Award
Second Prize of National Higher Education Scientific Research Outstanding Achievement Award
First Prize of Zhejiang Province Medical and Health Science and Technology Award

Areas of Focus	Mechanisms of stem/progenitor cells in vascular diseases Non-coding RNA in vascular remodeling Metabolic regulation of atherosclerosis and vascular aging
Publications	Cardiovascular Complications of Pan-Cancer Therapies: The Need for Cardio-Oncology, Chen M, Xue J, Wang M, Yang J, Chen T, 2023 Multilineage commitment of Sca-1+ cells in reshaping vein grafts, Ni Z, Lyu L, Gong H, Du L, Wen Z, Jiang H, Yang H, Hu Y, Zhang B, Xu Q, Guo X, Chen T, 2023 Host CD34+ Cells Are Replacing Donor Endothelium of Transplanted Heart, Chen T, Sun X, Gong H, Chen M, Li Y, Wang T, Huang X, Wen Z, Xue J, Teng P, Hu Y, Zhang L, Yang J, Xu Q, Li W, 2023 Nonbone Marrow CD34+ Cells Are Crucial for Endothelial Repair of Injured Artery, Jiang L, Chen T, Sun S, Wang R, Deng J, Lyu L, Wu H, Yang M, Pu X, Du L, Chen Q, Hu Y, Hu X, Zhou Y, Xu Q, Zhang L, 2021 Fate mapping RNA-sequencing reveal Malat1 regulates Sca1+ progenitor cells to vascular smooth muscle cells transition in vascular remodeling, Lyu L, Li Z, Wen Z, He Y, Wang X, Jiang L, Zhou X, Huang C, Wu Y, Chen T, Guo X, 2023 Single cell and lineage tracing studies reveal the impact of CD34+ cells on myocardial fibrosis during heart failure, Du L, Sun X, Gong H, Wang T, Jiang L, Huang C, Xu X, Li Z, Xu H, Ma L, Li W, Chen T, Xu Q, 2023 DKK3 (Dikkopf-3) Transdifferentiates Fibroblasts Into Functional Endothelial Cells-Brief Report, Chen T, Karamariti E, Hong X, Deng J, Wu Y, Gu W, Simpson R, Wong MM, Yu B, Hu Y, Qu A, Xu Q, Zhang L, 2019 MiR-30c-5p regulates adventitial progenitor cells differentiation to vascular smooth muscle cells through targeting OPG, Zhang Q, Chen T, Zhang Y, Lyu L, Zhang B, Huang C, Zhou X, Wu Y, Li Z, 2021 Genetic liability to obesity and peptic ulcer disease: a Mendelian randomization study, Li Z, Chen H, Chen T, 2022 Response of vascular mesenchymal stem/progenitor cells to hyperlipidemia, Chen T, Wu Y, Gu W, Xu Q, 2018 MicroRNA-29a promotes smooth muscle cell differentiation from stem cells by targeting YY1, Jin M, Wu Y, Wang Y, Yu D, Yang M, Yang F, Feng C, Chen T, 2016 MicroRNA-199a induces differentiation of induced pluripotent stem cells into endothelial cells by targeting sirtuin 1, Li Z, Margariti A, Wu Y, Yang F, Hu J, Zhang L, Chen T, 2015 Microrna-199b modulates vascular cell fate during ips cell differentiation by targeting the notch ligand jagged1 and enhancing vegf signaling, Chen T, Margariti A, Kelaini S, Cochrane A, Guha ST, Hu Y, Stitt AW, Zhang L, Xu Q, 2015 MicroRNA-146a regulates the maturation process and pro-inflammatory cytokine secretion by targeting CD40L in oxLDL-stimulated dendritic cells, Chen T, Li Z, Jing T, Zhu W, Ge J, Zheng X, Pan X, Yan H, Zhu J, 2011 MicroRNA-29a regulates pro-Inflammatory cytokine secretion and scavenger receptor expression by targeting LPL in oxLDL-stimulated dendritic cells, Chen T, Li Z, Tu J, Zhu W, Ge J, Zheng X, Yang L, Pan X, Yan H, Zhu J, 2011 MicroRNA-155 regulates lipid uptake, adhesion/chemokine marker secretion and SCG2 expression in oxLDL-stimulated dendritic cells/macrophages, Chen T, Yan H, Li Z, Jing T, Zhu W, Ge J, Zheng X, Pan X, Yan H, Zhu J, 2011 MicroRNA-125a-5p partly regulates the inflammatory response, lipid uptake, and ORP9 expression in oxLDL-stimulated monocyte/macrophages, Chen T, Huang Z, Wang L, Wang Y, Wu F, Meng S, Wang C, 2009 Multilineage contribution of CD34+ cells in cardiac remodeling after ischemia/reperfusion injury, Xie J, Jiang L, Wang J, Yin Y, Wang R, Du L, Chen T, Ni Z, Qiao S, Gong H, Xu B, Xu Q, 2023 CD34+ cell atlas of main organs implicates its impact on fibrosis, Pu X, Zhu P, Zhou X, He Y, Wu H, Du L, Gong H, Sun X, Chen T, Zhu J, Xu Q, Zhang H, 2022 Single-cell gene profiling and lineage tracing analyses revealed novel mechanisms of endothelial repair by progenitors, Deng J, Ni Z, Gu W, Chen Q, Nowak WN, Chen T, Issa Bhaloo S, Zhang Z, Hu Y, Zhou B, Zhang L, Xu Q, 2020 Adventitial Cell Atlas of wt (Wild Type) and ApoE (Apolipoprotein E)-Deficient Mice Defined by Single-Cell RNA Sequencing, Gu W, Ni Z, Tan YQ, Deng J, Zhang SJ, Lv ZC, Wang XJ, Chen T, Zhang Z, Hu Y, Jing ZC, Xu Q, 2019 Recipient c-Kit Lineage Cells Repopulate Smooth Muscle Cells of Transplant Arteriosclerosis in Mouse Models, Ni Z, Deng J, Potter CMF, Nowak WN, Gu W, Zhang Z, Chen T, Chen Q, Hu Y, Zhou B, Xu Q, Zhang L, 2019 Role of Resident Stem Cells in Vessel Formation and Arteriosclerosis, Zhang L, Issa Bhaloo S, Chen T, Zhou B, Xu Q, 2018 An updated view on the differentiation of stem cells into endothelial cells, Zhou Y, Yang F, Chen T, Wu Y, Yang M, Zhu J, Zhang L, 2014 XBP1 mRNA splicing triggers an autophagic response in endothelial cells through beclin-1 transcriptional activation, Margariti A, Li H, Chen T, Martin D, Vizcay-Barrena G, Alam S, Karamariti E, Xiao Q, Zampetaki A, Zhang Z, Wang W, Jiang Z, Gao C, Ma B, Chen YG, Cockerill GW, Hu Y, Xu Q, Zeng L, 2013 Sirolimus stimulates vascular stem/progenitor cell migration and differentiation into smooth muscle cells via epidermal growth factor receptor/extracellular signal-regulated kinase/β-catenin signaling pathway, Wong MM, Winkler B, Karamariti E, Wang X, Yu B, Simpson R, Chen T, Margariti A, Xu Q, 2013 Angiotensin II promotes differentiation of mouse embryonic stem cells to smooth muscle cells through PI3-kinase signaling pathway and NF-κB, Zheng X, Wu Y, Zhu L, Chen Q, Zhou Y, Yan H, Chen T, Xiao Q, Zhu J, Zhang L, 2013 Distinct MAPK pathways are involved in IL-23 production in dendritic cells cocultured with NK cells in the absence or presence of angiotensin II, Yang L, Du C, Chen T, Li S, Nie W, Zhu W, Fan F, Zhu J, Yan H, 2012 Suppression of oxLDL-induced MMP-9 and EMMPRIN expression by berberine via inhibition of NF-kappaB activation in human THP-1 macrophages, Huang Z, Wang L, Meng S, Wang Y, Chen T, Wang C, 2012 Heme oxygenase 1 regulates the maturation process and inflammatory response in oxLDL-stimulated dendritic cells, Yan H, Chen T, Li Z, Tujing, Zhu W, Ge J, Zheng X, Pan X, Zhu J, 2011 The anti-malarial artemisinin inhibits pro-inflammatory cytokines via the NF-κB canonical signaling pathway in PMA-induced THP-1 monocytes, Wang Y, Huang Z, Wang L, Meng S, Fan Y, Chen T, Cao J, Jiang R, Wang C, 2011 Berberine reduces both MMP-9 and EMMPRIN expression through prevention of p38 pathway activation in PMA-induced macrophages, Huang Z, Wang L, Meng S, Wang Y, Chen T, Wang C, 2011 Artemisinin inhibits extracellular matrix metalloproteinase inducer (EMMPRIN) and matrix metalloproteinase-9 expression via a protein kinase Cdelta/p38/extracellular signal-regulated kinase pathway in phorbol myristate acetate-induced THP-1 macrophages, Wang Y, Huang ZQ, Wang CQ, Wang LS, Meng S, Zhang YC, Chen T, Fan YQ, 2011

Areas of Focus

Mechanisms of stem/progenitor cells in vascular diseases
Non-coding RNA in vascular remodeling
Metabolic regulation of atherosclerosis and vascular aging

Publications

Cardiovascular Complications of Pan-Cancer Therapies: The Need for Cardio-Oncology, Chen M, Xue J, Wang M, Yang J, Chen T, 2023
Multilineage commitment of Sca-1+ cells in reshaping vein grafts, Ni Z, Lyu L, Gong H, Du L, Wen Z, Jiang H, Yang H, Hu Y, Zhang B, Xu Q, Guo X, Chen T, 2023
Host CD34+ Cells Are Replacing Donor Endothelium of Transplanted Heart, Chen T, Sun X, Gong H, Chen M, Li Y, Wang T, Huang X, Wen Z, Xue J, Teng P, Hu Y, Zhang L, Yang J, Xu Q, Li W, 2023
Nonbone Marrow CD34+ Cells Are Crucial for Endothelial Repair of Injured Artery, Jiang L, Chen T, Sun S, Wang R, Deng J, Lyu L, Wu H, Yang M, Pu X, Du L, Chen Q, Hu Y, Hu X, Zhou Y, Xu Q, Zhang L, 2021
Fate mapping RNA-sequencing reveal Malat1 regulates Sca1+ progenitor cells to vascular smooth muscle cells transition in vascular remodeling, Lyu L, Li Z, Wen Z, He Y, Wang X, Jiang L, Zhou X, Huang C, Wu Y, Chen T, Guo X, 2023
Single cell and lineage tracing studies reveal the impact of CD34+ cells on myocardial fibrosis during heart failure, Du L, Sun X, Gong H, Wang T, Jiang L, Huang C, Xu X, Li Z, Xu H, Ma L, Li W, Chen T, Xu Q, 2023
DKK3 (Dikkopf-3) Transdifferentiates Fibroblasts Into Functional Endothelial Cells-Brief Report, Chen T, Karamariti E, Hong X, Deng J, Wu Y, Gu W, Simpson R, Wong MM, Yu B, Hu Y, Qu A, Xu Q, Zhang L, 2019
MiR-30c-5p regulates adventitial progenitor cells differentiation to vascular smooth muscle cells through targeting OPG, Zhang Q, Chen T, Zhang Y, Lyu L, Zhang B, Huang C, Zhou X, Wu Y, Li Z, 2021
Genetic liability to obesity and peptic ulcer disease: a Mendelian randomization study, Li Z, Chen H, Chen T, 2022
Response of vascular mesenchymal stem/progenitor cells to hyperlipidemia, Chen T, Wu Y, Gu W, Xu Q, 2018
MicroRNA-29a promotes smooth muscle cell differentiation from stem cells by targeting YY1, Jin M, Wu Y, Wang Y, Yu D, Yang M, Yang F, Feng C, Chen T, 2016
MicroRNA-199a induces differentiation of induced pluripotent stem cells into endothelial cells by targeting sirtuin 1, Li Z, Margariti A, Wu Y, Yang F, Hu J, Zhang L, Chen T, 2015
Microrna-199b modulates vascular cell fate during ips cell differentiation by targeting the notch ligand jagged1 and enhancing vegf signaling, Chen T, Margariti A, Kelaini S, Cochrane A, Guha ST, Hu Y, Stitt AW, Zhang L, Xu Q, 2015
MicroRNA-146a regulates the maturation process and pro-inflammatory cytokine secretion by targeting CD40L in oxLDL-stimulated dendritic cells, Chen T, Li Z, Jing T, Zhu W, Ge J, Zheng X, Pan X, Yan H, Zhu J, 2011
MicroRNA-29a regulates pro-Inflammatory cytokine secretion and scavenger receptor expression by targeting LPL in oxLDL-stimulated dendritic cells, Chen T, Li Z, Tu J, Zhu W, Ge J, Zheng X, Yang L, Pan X, Yan H, Zhu J, 2011
MicroRNA-155 regulates lipid uptake, adhesion/chemokine marker secretion and SCG2 expression in oxLDL-stimulated dendritic cells/macrophages, Chen T, Yan H, Li Z, Jing T, Zhu W, Ge J, Zheng X, Pan X, Yan H, Zhu J, 2011
MicroRNA-125a-5p partly regulates the inflammatory response, lipid uptake, and ORP9 expression in oxLDL-stimulated monocyte/macrophages, Chen T, Huang Z, Wang L, Wang Y, Wu F, Meng S, Wang C, 2009
Multilineage contribution of CD34+ cells in cardiac remodeling after ischemia/reperfusion injury, Xie J, Jiang L, Wang J, Yin Y, Wang R, Du L, Chen T, Ni Z, Qiao S, Gong H, Xu B, Xu Q, 2023
CD34+ cell atlas of main organs implicates its impact on fibrosis, Pu X, Zhu P, Zhou X, He Y, Wu H, Du L, Gong H, Sun X, Chen T, Zhu J, Xu Q, Zhang H, 2022
Single-cell gene profiling and lineage tracing analyses revealed novel mechanisms of endothelial repair by progenitors, Deng J, Ni Z, Gu W, Chen Q, Nowak WN, Chen T, Issa Bhaloo S, Zhang Z, Hu Y, Zhou B, Zhang L, Xu Q, 2020
Adventitial Cell Atlas of wt (Wild Type) and ApoE (Apolipoprotein E)-Deficient Mice Defined by Single-Cell RNA Sequencing, Gu W, Ni Z, Tan YQ, Deng J, Zhang SJ, Lv ZC, Wang XJ, Chen T, Zhang Z, Hu Y, Jing ZC, Xu Q, 2019
Recipient c-Kit Lineage Cells Repopulate Smooth Muscle Cells of Transplant Arteriosclerosis in Mouse Models, Ni Z, Deng J, Potter CMF, Nowak WN, Gu W, Zhang Z, Chen T, Chen Q, Hu Y, Zhou B, Xu Q, Zhang L, 2019
Role of Resident Stem Cells in Vessel Formation and Arteriosclerosis, Zhang L, Issa Bhaloo S, Chen T, Zhou B, Xu Q, 2018
An updated view on the differentiation of stem cells into endothelial cells, Zhou Y, Yang F, Chen T, Wu Y, Yang M, Zhu J, Zhang L, 2014
XBP1 mRNA splicing triggers an autophagic response in endothelial cells through beclin-1 transcriptional activation, Margariti A, Li H, Chen T, Martin D, Vizcay-Barrena G, Alam S, Karamariti E, Xiao Q, Zampetaki A, Zhang Z, Wang W, Jiang Z, Gao C, Ma B, Chen YG, Cockerill GW, Hu Y, Xu Q, Zeng L, 2013
Sirolimus stimulates vascular stem/progenitor cell migration and differentiation into smooth muscle cells via epidermal growth factor receptor/extracellular signal-regulated kinase/β-catenin signaling pathway, Wong MM, Winkler B, Karamariti E, Wang X, Yu B, Simpson R, Chen T, Margariti A, Xu Q, 2013
Angiotensin II promotes differentiation of mouse embryonic stem cells to smooth muscle cells through PI3-kinase signaling pathway and NF-κB, Zheng X, Wu Y, Zhu L, Chen Q, Zhou Y, Yan H, Chen T, Xiao Q, Zhu J, Zhang L, 2013
Distinct MAPK pathways are involved in IL-23 production in dendritic cells cocultured with NK cells in the absence or presence of angiotensin II, Yang L, Du C, Chen T, Li S, Nie W, Zhu W, Fan F, Zhu J, Yan H, 2012
Suppression of oxLDL-induced MMP-9 and EMMPRIN expression by berberine via inhibition of NF-kappaB activation in human THP-1 macrophages, Huang Z, Wang L, Meng S, Wang Y, Chen T, Wang C, 2012
Heme oxygenase 1 regulates the maturation process and inflammatory response in oxLDL-stimulated dendritic cells, Yan H, Chen T, Li Z, Tujing, Zhu W, Ge J, Zheng X, Pan X, Zhu J, 2011
The anti-malarial artemisinin inhibits pro-inflammatory cytokines via the NF-κB canonical signaling pathway in PMA-induced THP-1 monocytes, Wang Y, Huang Z, Wang L, Meng S, Fan Y, Chen T, Cao J, Jiang R, Wang C, 2011
Berberine reduces both MMP-9 and EMMPRIN expression through prevention of p38 pathway activation in PMA-induced macrophages, Huang Z, Wang L, Meng S, Wang Y, Chen T, Wang C, 2011
Artemisinin inhibits extracellular matrix metalloproteinase inducer (EMMPRIN) and matrix metalloproteinase-9 expression via a protein kinase Cdelta/p38/extracellular signal-regulated kinase pathway in phorbol myristate acetate-induced THP-1 macrophages, Wang Y, Huang ZQ, Wang CQ, Wang LS, Meng S, Zhang YC, Chen T, Fan YQ, 2011

Stem Cells Progenitor Cells Vascular Diseases Non-Coding Rna Vascular Remodeling Metabolic Regulation Atherosclerosis Vascular Aging Endothelial Repair Cardiovascular Research

Qingbo Xu - Zhejiang University

Xinjiang Lu - Zhejiang University

Jie Sun - Zhejiang University

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