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Yewei Ji
Medical School
Zhejiang University
Zhejiang
Language: English, Chinese
Immunity
Tumors
Metabolic Diseases
Chronic Inflammation
Innate Immunity
Molecular Pathology
Erad
B Lymphocytes
Sting Pathway
Upr
Areas of Focus
- Immunity and Tumors, Metabolic Diseases
- Endoplasmic Reticulum Homeostasis Regulation
Work Experience
- Until 2020 - Cornell University - Postdoctoral Researcher
- Until 2020 - University of Michigan - Research Investigator
- From 2020 - Zhejiang University First Affiliated Hospital - Distinguished Researcher
Academic Background & Achievements
- Clinical Medicine Master's: Not mentioned
- PhD in Basic Medicine: Not mentioned
- Postdoctoral Research: Cornell University and University of Michigan
- Published representative papers in top journals like Nature Cell Biology, Nature Immunology, Cell Reports, JBC
- H-index: 21
- Over 2300 citations
- Two US patents
- American Heart Association Scientist Career Development Fund (2017)
- National Natural Science Foundation of China (2022-2025; 2024-2028)
- University of Michigan Department of Physiology Outstanding Researcher Award (2019)
Publications
- ER, an emerging hub for regulation of STING, Luo Y, Chang L, Ji Y, Liang T, 2024
- SEL1L-HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of activable STING pool, Ji Y, Luo Y, Wu Y, Sun Y, Zhao L, Xue Z, Sun M, Wei X, He Z, Wu SA, Lin LL, Lu Y, Chang L, Chen F, Chen S, Qian W, Xu X, Chen S, Pan D, Zhou Z, Xia S, Hu CA, Liang T, Qi L, 2023
- Toll-like receptors TLR2 and TLR4 block the replication of pancreatic β cells in diet-induced obesity, Ji Y, Sun S, Shrestha N, Darragh L, Shirakawa J, Xing Y, He Y, Carboneau B, Kim H, An D, Ma M, Oberholzer J, Soleimanpour S, Maureen G, Liu C, Naji A, Kulkarni R, Wang Y, Kersten S, Qi L, 2019
- The Sel1L-Hrd1 Endoplasmic Reticulum-Associated Degradation Complex Manages a Key Checkpoint in B Cell Development, Ji Y, Kim H, Yang L, Sha H, Roman CA, Long Q, Qi L, 2016
- Diet-induced alterations in gut microflora contribute to lethal pulmonary damage in TLR2/TLR4-deficient mice, Ji Y, Sun S, Goodrich JK, Kim H, Poole AC, Duhamel GE, Ley RE, Qi L, 2014
- Activation of natural killer T cells promotes M2 Macrophage polarization in adipose tissue and improves systemic glucose tolerance via interleukin-4 (IL-4)/STAT6 protein signaling axis in obesity, Ji Y, Sun S, Xu A, Bhargava P, Yang L, Lam KS, Gao B, Lee CH, Kersten S, Qi L, 2012
- Short term high fat diet challenge promotes alternative macrophage polarization in adipose tissue via natural killer T cells and interleukin-4, Ji Y, Sun S, Xia S, Yang L, Li X, Qi L, 2012
Awards
- American Heart Association Scientist Career Development Fund (2017)
- National Natural Science Foundation of China (2022-2025; 2024-2028)
- University of Michigan Department of Physiology Outstanding Researcher Award (2019)
