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Yunjie Chang
Medical
Zhejiang University
Zhejiang
Language: Chinese, English
Bacterial Motility
Antibiotic Resistance
Neural Signal Transduction
Cryo-Electron Tomography
Protein Structure
Molecular Machines
Flagellar Motor
Secretion Systems
Ribosomes
Image Processing
Areas of Focus
- Mechanisms of bacterial motility and antibiotic resistance
- Mechanisms of neural signal transduction
- In situ structural and functional analysis of biological macromolecular complexes
Work Experience
- 2022.02-Present - Zhejiang University School of Medicine - Distinguished Researcher
- 2017.07-2021.12 - Yale University School of Medicine - Postdoctoral Researcher
Academic Background & Achievements
- 2011.09-2017.07 Ph.D. in Condensed Matter Physics: Institute of Physics, Chinese Academy of Sciences
- 2007.09-2011.06 Bachelor of Science: Wuhan University
Publications
- Characterization of the flagellar collar reveals structural plasticity essential for spirochete motility, Yunjie Chang, Hui Xu, Md A Motaleb, Jun Liu, 2021
- Structural basis for bacterial flagellar motor rotation and switching, Yunjie Chang, Brittany Carroll, Jun Liu, 2021
- Molecular mechanism for rotational switching of the bacterial flagellar motor, Yunjie Chang, Kai Zhang, Brittany Carroll, Xiaowei Zhao, Nyles W Charon, Steven J Norris, Md A Motaleb, Chunhao Li, Jun Liu, 2020
- In situ structural analysis of bacterial nanomachines by combining cryo-FIB milling, cryo-ET and sub-tomogram analysis, Yunjie Chang, Jun Liu, 2020
- Structural insights into flagellar stator–rotor interactions, Yunjie Chang, Ki Hwan Moon, Xiaowei Zhao, Steven J Norris, MD A Motaleb, Jun Liu, 2019
- Architecture and assembly of periplasmic flagellum, Yunjie Chang, Jun Liu, 2019
- Applicability of non-linear imaging in high-resolution transmission electron microscopy, Yunjie Chang, Shouqing Li, Yumei Wang, Binghui Ge, 2017
- Investigation of non-linear imaging in high-resolution transmission electron microscopy, Yunjie Chang, Yumei Wang, Yanxiang Cui, Binghui Ge, 2016
- Investigations of atomic configurations of 60° basal dislocations in wurtzite GaN film by high-resolution transmission electron microscopy, Yunjie Chang, Yumei Wang, Zhen Deng, Hong Chen, Binghui Ge, 2016
- FliL ring enhances the function of periplasmic flagella, Shuaiqi Guo, Hui Xu, Yunjie Chang, Md A Motaleb, Jun Liu, 2021
- Interconnecting solvent quality, transcription, and chromosome folding in Escherichia coli, Yingjie Xiang, Ivan V Surovtsev, Yunjie Chang, Sander K Govers, Bradley R Parry, Jun Liu, Christine Jacobs-Wagner, 2021
- Composition and Biophysical Properties of the Sorting Platform Pods in the Shigella Type III Secretion System, Shoichi Tachiyama, Ryan Skaar, Yunjie Chang, Brittany Carroll, Meenakumari Muthuramalingam, Sean Whittier, Michael L Barta, Wendy L Picking, Jun Liu, William D Picking, 2021
- A CRISPR interference platform for selective downregulation of gene expression in Borrelia burgdorferi, Constantin N Takacs, Molly Scott, Yunjie Chang, Zachary A Kloos, Irnov Irnov, Patricia A Rosa, Jun Liu, Christine Jacobs-Wagner, 2021
- The peptidoglycan-associated protein NapA plays an important role in the envelope integrity and in the pathogenesis of the lyme disease spirochete, Marisela M. Davis, Aaron M. Brock, Tanner G. DeHart, Brittany P. Boribong, Katherine Lee, Mecaila E. McClune, Yunjie Chang, Nicholas Cramer, Jun Liu, Caroline N. Jones, Brandon L. Jutras, 2021
- A mammalian system for high-resolution imaging of intact cells by cryo-electron tomography, Xia Li, Donghyun Park, Yunjie Chang, Abhijith Radhakrishnan, Hangjun Wu, Pei Wang, Jun Liu, 2020
- Revealing the origin of dislocations in Pb1-xSb2x/3Se(0< x≤ 0.07), Pengfei Nan, Yunjie Chang, Zhiwei Chen, Yanzhong Pei, Yongsheng Zhang, Yumei Wang, Binghui Ge, 2020
- The cytoplasmic domain of MxiG interacts with MxiK and directs assembly of the sorting platform in the Shigella type III secretion system, Shoichi Tachiyama, Yunjie Chang, Meenakumari Muthuramalingam, Bo Hu, Michael L Barta, Wendy L Picking, Jun Liu, William D Picking, 2019
- Development of an intact mammalian system for high-resolution imaging by cryo-electron tomography, Xia Li, Donghyun Park, Yunjie Chang, Abhijith Radhakrishnan, Hangjun Wu, Jun Liu, 2019
- A review of sample thickness effects on high-resolution transmission electron microscopy imaging, Shouqing Li, Yunjie Chang, Yumei Wang, Qiang Xu, Binghui Ge, 2019
- Analysis of a flagellar filament cap mutant reveals that HtrA serine protease degrades unfolded flagellin protein in the periplasm of Borrelia burgdorferi, Kai Zhang, Zhuan Qin, Yunjie Chang, Jun Liu, Michael G Malkowski, Saimtun Shipa, Li Li, Weigang Qiu, Jing‐Ren Zhang, Chunhao Li, 2019
- Microscopic study of thermoelectric In-doped SnTe, Pengfei Nan, Ruibin Liu, Yunjie Chang, Hongbo Wu, Yumei Wang, Richeng Yu, Jun Shen, Wei Guo, Binghui Ge, 2018
- Lattice dislocations enhancing thermoelectric PbTe in addition to band convergence, Zhiwei Chen, Zhengzhong Jian, Wen Li, Yunjie Chang, Binghui Ge, Riley Hanus, Jiong Yang, Yue Chen, Mingxin Huang, Gerald Jeffrey Snyder, Yanzhong Pei, 2017
- Promoting SnTe as an eco‐friendly solution for p‐PbTe thermoelectric via band convergence and interstitial defects, Wen Li, Linglang Zheng, Binghui Ge, Siqi Lin, Xinyue Zhang, Zhiwei Chen, Yunjie Chang, Yanzhong Pei, 2017
- Vacancy-induced dislocations within grains for high-performance PbSe thermoelectrics, Zhiwei Chen, Binghui Ge, Wen Li, Siqi Lin, Jiawen Shen, Yunjie Chang, Riley Hanus, G Jeffrey Snyder, Yanzhong Pei, 2017
- Study of microstructure of nickel-based superalloys at high temperatures, Qinghua Zhang, Yunjie Chang, Lin Gu, Yushi Luo, Binghui Ge, 2017
- Atom-thin SnS2–xSex with adjustable compositions by direct liquid exfoliation from single crystals, Zhanhai Yang, Hui Liang, Xusheng Wang, Xinlei Ma, Tao Zhang, Yanlian Yang, Liming Xie, Dong Chen, Yujia Long, Jitao Chen, Yunjie Chang, Chunhua Yan, Xinxiang Zhang, Xueji Zhang, Binghui Ge, Zhian Ren, Mianqi Xue, Genfu Chen, 2016
- Band and scattering tuning for high performance thermoelectric Sn1−xMnxTe alloys, Wen Li, Zhiwei Chen, Siqi Lin, Yunjie Chang, Binghui Ge, Yue Chen, Yanzhong Pei, 2015
- Study of point spread in the aberration-corrected transmission electron microscopy, Binghui Ge, Yumei Wang, Yunjie Chang, Yuan Yao, 2014
