Professor | Ying Yang | Asia Growth Partners

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Name	Ying Yang
Contact Information	rebecca_yang@zju.edu.cn
Language ability	Chinese, English
Province	Zhejiang

Upload Avatar (500 x 500)

Name

Ying Yang

Contact Information

rebecca_yang@zju.edu.cn

Language ability

Chinese, English

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Medical
Academic Background & Achievements	2009-09 to 2013-07 Bachelor of Science: Peking University, School of Life Sciences 2014-01 to 2018-07 Ph.D.: National University of Singapore, School of Life Sciences (Supervisor: Cai Yu)
Work Experience	2018-10 to 2021-09 - Peking University Health Science Center, School of Basic Medical Sciences - Postdoctoral Researcher (Supervisor: Zhang Jing) 2021-12 to Present - Zhejiang University, The First Affiliated Hospital - Distinguished Associate Researcher
Awards	Zhejiang Provincial Science and Technology Department, Natural Science, Provincial Second Prize (2023): Innovation in the theory and mechanism of major brain disease diagnosis and treatment based on peripheral blood cell extracellular vesicles

University/Lab Affiliation and Title

Zhejiang University

Faculty

Medical

Academic Background & Achievements

2009-09 to 2013-07 Bachelor of Science: Peking University, School of Life Sciences
2014-01 to 2018-07 Ph.D.: National University of Singapore, School of Life Sciences (Supervisor: Cai Yu)

Work Experience

2018-10 to 2021-09 - Peking University Health Science Center, School of Basic Medical Sciences - Postdoctoral Researcher (Supervisor: Zhang Jing)
2021-12 to Present - Zhejiang University, The First Affiliated Hospital - Distinguished Associate Researcher

Awards

Zhejiang Provincial Science and Technology Department, Natural Science, Provincial Second Prize (2023): Innovation in the theory and mechanism of major brain disease diagnosis and treatment based on peripheral blood cell extracellular vesicles

Areas of Focus	Mechanisms of Parkinson's Disease and Early Biomarker Research
Publications	Evolving insights into erythrocytes in synucleinopathies, Yang, Y., Nie, X., Wang, Y., Sun, J., Gao, X.#, & Zhang, J.#, 2024 Erythrocytic α-Synuclein and the Gut Microbiome: Kindling of the Gut-Brain Axis in Parkinson’s Disease, Yang,Y., Stewart, T., Zhang, C., Wang, P., Xu, Z., Jin, J., Huang, Y., Liu, Z., Lan, G., Liang, X., Sheng, L., Shi, M., Cai, Z., Zhang, J., 2024 Calcium Influx: An Essential Process by which α-Synuclein Regulates Morphology of Erythrocytes, Yang,Y., Shi, M., Liu, X.*, Zhu, Q., Xu, Z., Liu, Z., Feng, T.#, Stewart, T.#, Zhang, J#., 2024 dRTEL1 is essential for the maintenance of Drosophila male germline stem cells, Yang, Y., Kong, R., Goh, F. G., Somers, W. G., Hime, G. R., Li, Z., & Cai, Y., 2021 α-Synuclein-carrying astrocytic extracellular vesicles in Parkinson pathogenesis and diagnosis, Wang, P., Lan, G., Xu, B., Yu, Z., Tian, C., Lei, X., Meissner, W. G., Feng, T.#, Yang, Y.#, & Zhang, J#., 2023 Gut-derived β-amyloid: Likely a centerpiece of the gut-brain axis contributing to Alzheimer's pathogenesis, Jin, J., Xu, Z., Zhang, L., Zhang, C., Zhao, X., Mao, Y., Zhang, H., Liang, X., Wu, J., Yang, Y.#, & Zhang, J#., 2023 The cervical lymph node contributes to peripheral inflammation related to Parkinson's disease, Liu, Z., Huang, Y., Wang, X., Li, J. Y., Zhang, C., Yang, Y.#, & Zhang, J., 2023 GV-971 attenuates α-Synuclein aggregation and related pathology, Yu, Z.#, Yang, Y.#, Chan, R. B., Shi, M., Stewart, T., Huang, Y., Liu, Z., Lan, G., Sheng, L., Tian, C., Yang, D., & Zhang, J., 2023 α-Synuclein-containing erythrocytic extracellular vesicles: essential contributors to hyperactivation of monocytes in Parkinson's disease, Liu, Z., Chan, R. B., Cai, Z., Liu, X., Wu, Y., Yu, Z., Feng, T., Yang, Y.#, & Zhang, J#., 2022 Astrocytic VEGFA: An essential mediator in blood-brain-barrier disruption in Parkinson's disease, Lan, G., Wang, P., Chan, R. B., Liu, Z., Yu, Z., Liu, X., Yang, Y.#, & Zhang, J#., 2022 Exosomal microRNAs induce tumor-associated macrophages via PPARγ during tumor progression in SHH medulloblastoma, Zhu, L.#, Yang, Y.#, Li, H.#, Xu, L., You, H., Liu, Y., Liu, Z., Liu, X., Zheng, D., Bie, J., Li, J., Song, C., Yang, B., Luo, J., & Chang, Q., 2022 MED13 and glycolysis are conserved modifiers of α-synuclein-associated neurodegeneration, Ren, M.#, Yang, Y.#, Heng, K. H. Y., Ng, L. Y., Chong, C. Y., Ng, Y. T., Gorur-Shandilya, S., Lee, R. M. Q., Lim, K. L., Zhang, J., & Koh, T. W., 2022 Reduced erythrocytic CHCHD2 mRNA is associated with brain pathology of Parkinson's disease, Liu, X.#, Wang, Q.#, Yang, Y.#, Stewart, T., Shi, M., Soltys, D., Liu, G., Thorland, E., Cilento, E. M., Hou, Y., Liu, Z., Feng, T., & Zhang, J., 2021 Par complex cluster formation mediated by phase separation, Liu, Z.#, Yang, Y.#, Gu, A.#, Xu, J., Mao, Y., Lu, H., Hu, W., Lei, Q. Y., Li, Z., Zhang, M., Cai, Y., & Wenyu Wen., 2020 Basal condensation of Numb and Pon complex via phase transition during Drosophila neuroblast asymmetric division, Shan, Z.#, Tu, Y.#,Yang, Y.#,Liu, Z., Zeng, M., Xu, H., Long, J., Zhang, M., Cai, Y., & Wenyu Wen., 2018 The structural basis of Miranda-mediated Staufen localization during Drosophila neuroblast asymmetric division, Jia M.#, Shan, Z.#, Yang, Y.#, Liu, C., Li, J., Luo, Z. G., Zhang, M., Cai, Y., Wen, W., &Wang, W., 2015 The Integrator complex desensitizes cellular response to TGF-β/BMP signaling, Liu, S., Baeg, G. H., Yang, Y., Goh, F. G., Bao, H., Wagner, E. J., Yang, X., & Cai, Y., 2023 Phosphotyrosyl phosphatase activator facilitates localization of Miranda through dephosphorylation in dividing neuroblasts, Zhang, F., Huang, Z.X., Bao, H., Cong, F., Wang, H., Chai, P.C., Xi, Y., Ge, W., Somers, W.G., Yang, Y. , Cai, Y., and Yang, X., 2016 Coordinated niche-associated signals promote germline homeostasis in the Drosophila ovary, Liu, Z., Zhong, G., Chai, P. C., Luo, L., Liu, S., Yang, Y., Baeg, G. H., & Cai, Y., 2015

Areas of Focus

Mechanisms of Parkinson's Disease and Early Biomarker Research

Publications

Evolving insights into erythrocytes in synucleinopathies, Yang, Y.*, Nie, X.*, Wang, Y., Sun, J., Gao, X.#, & Zhang, J.#, 2024
Erythrocytic α-Synuclein and the Gut Microbiome: Kindling of the Gut-Brain Axis in Parkinson’s Disease, Yang,Y.*, Stewart, T.*, Zhang, C., Wang, P., Xu, Z., Jin, J., Huang, Y., Liu, Z., Lan, G., Liang, X., Sheng, L., Shi, M., Cai, Z., Zhang, J., 2024
Calcium Influx: An Essential Process by which α-Synuclein Regulates Morphology of Erythrocytes, Yang,Y*., Shi, M.*, Liu, X.*, Zhu, Q., Xu, Z., Liu, Z., Feng, T.#, Stewart, T.#, Zhang, J#., 2024
dRTEL1 is essential for the maintenance of Drosophila male germline stem cells, Yang, Y., Kong, R., Goh, F. G., Somers, W. G., Hime, G. R., Li, Z., & Cai, Y., 2021
α-Synuclein-carrying astrocytic extracellular vesicles in Parkinson pathogenesis and diagnosis, Wang, P., Lan, G., Xu, B., Yu, Z., Tian, C., Lei, X., Meissner, W. G., Feng, T.#, Yang, Y.#, & Zhang, J#., 2023
Gut-derived β-amyloid: Likely a centerpiece of the gut-brain axis contributing to Alzheimer's pathogenesis, Jin, J., Xu, Z., Zhang, L., Zhang, C., Zhao, X., Mao, Y., Zhang, H., Liang, X., Wu, J., Yang, Y.#, & Zhang, J#., 2023
The cervical lymph node contributes to peripheral inflammation related to Parkinson's disease, Liu, Z., Huang, Y., Wang, X., Li, J. Y., Zhang, C., Yang, Y.#, & Zhang, J., 2023
GV-971 attenuates α-Synuclein aggregation and related pathology, Yu, Z.#, Yang, Y.#, Chan, R. B., Shi, M., Stewart, T., Huang, Y., Liu, Z., Lan, G., Sheng, L., Tian, C., Yang, D., & Zhang, J., 2023
α-Synuclein-containing erythrocytic extracellular vesicles: essential contributors to hyperactivation of monocytes in Parkinson's disease, Liu, Z., Chan, R. B., Cai, Z., Liu, X., Wu, Y., Yu, Z., Feng, T., Yang, Y.#, & Zhang, J#., 2022
Astrocytic VEGFA: An essential mediator in blood-brain-barrier disruption in Parkinson's disease, Lan, G., Wang, P., Chan, R. B., Liu, Z., Yu, Z., Liu, X., Yang, Y.#, & Zhang, J#., 2022
Exosomal microRNAs induce tumor-associated macrophages via PPARγ during tumor progression in SHH medulloblastoma, Zhu, L.#, Yang, Y.#, Li, H.#, Xu, L., You, H., Liu, Y., Liu, Z., Liu, X., Zheng, D., Bie, J., Li, J., Song, C., Yang, B., Luo, J., & Chang, Q., 2022
MED13 and glycolysis are conserved modifiers of α-synuclein-associated neurodegeneration, Ren, M.#, Yang, Y.#, Heng, K. H. Y., Ng, L. Y., Chong, C. Y., Ng, Y. T., Gorur-Shandilya, S., Lee, R. M. Q., Lim, K. L., Zhang, J., & Koh, T. W., 2022
Reduced erythrocytic CHCHD2 mRNA is associated with brain pathology of Parkinson's disease, Liu, X.#, Wang, Q.#, Yang, Y.#, Stewart, T., Shi, M., Soltys, D., Liu, G., Thorland, E., Cilento, E. M., Hou, Y., Liu, Z., Feng, T., & Zhang, J., 2021
Par complex cluster formation mediated by phase separation, Liu, Z.#, Yang, Y.#, Gu, A.#, Xu, J., Mao, Y., Lu, H., Hu, W., Lei, Q. Y., Li, Z., Zhang, M., Cai, Y., & Wenyu Wen., 2020
Basal condensation of Numb and Pon complex via phase transition during Drosophila neuroblast asymmetric division, Shan, Z.#, Tu, Y.#,Yang, Y.#,Liu, Z., Zeng, M., Xu, H., Long, J., Zhang, M., Cai, Y., & Wenyu Wen., 2018
The structural basis of Miranda-mediated Staufen localization during Drosophila neuroblast asymmetric division, Jia M.#, Shan, Z.#, Yang, Y.#, Liu, C., Li, J., Luo, Z. G., Zhang, M., Cai, Y., Wen, W., &Wang, W., 2015
The Integrator complex desensitizes cellular response to TGF-β/BMP signaling, Liu, S., Baeg, G. H., Yang, Y., Goh, F. G., Bao, H., Wagner, E. J., Yang, X., & Cai, Y., 2023
Phosphotyrosyl phosphatase activator facilitates localization of Miranda through dephosphorylation in dividing neuroblasts, Zhang, F., Huang, Z.X., Bao, H., Cong, F., Wang, H., Chai, P.C., Xi, Y., Ge, W., Somers, W.G., Yang, Y. , Cai, Y., and Yang, X., 2016
Coordinated niche-associated signals promote germline homeostasis in the Drosophila ovary, Liu, Z., Zhong, G., Chai, P. C., Luo, L., Liu, S., Yang, Y., Baeg, G. H., & Cai, Y., 2015

Parkinson'S Disease Mechanisms Early Biomarkers Neuroscience Neurodegeneration Synucleinopathies Erythrocytes Gut-Brain Axis Calcium Influx Extracellular Vesicles

Yudong Zhou - Zhejiang University

Hao Wang - Zhejiang University

Xiongjie Yu - Zhejiang University

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