Professor | Liang Shi | Asia Growth Partners

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Name	Liang Shi
Contact Information	liang_shi@zju.edu.cn
Language ability	Chinese, English
Province	Zhejiang

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Name

Liang Shi

Contact Information

liang_shi@zju.edu.cn

Language ability

Chinese, English

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Medical
Academic Background & Achievements	Ph.D. in Surgery: Zhejiang University Postdoctoral Research: University of Rochester Cancer Institute Postdoctoral Research: Zhejiang University Outstanding Postdoctoral Fellow: Zhejiang Province Representative Postdoctoral Fellow: Zhejiang Province
Work Experience	Current - Zhejiang University School of Medicine Affiliated Sir Run Run Shaw Hospital - Attending Physician, Distinguished Associate Researcher Current - Zhejiang University - Master's Supervisor
Awards	Outstanding Postdoctoral Fellow: Zhejiang Province Representative Postdoctoral Fellow: Zhejiang Province

University/Lab Affiliation and Title

Zhejiang University

Faculty

Medical

Academic Background & Achievements

Ph.D. in Surgery: Zhejiang University
Postdoctoral Research: University of Rochester Cancer Institute
Postdoctoral Research: Zhejiang University
Outstanding Postdoctoral Fellow: Zhejiang Province
Representative Postdoctoral Fellow: Zhejiang Province

Work Experience

Current - Zhejiang University School of Medicine Affiliated Sir Run Run Shaw Hospital - Attending Physician, Distinguished Associate Researcher
Current - Zhejiang University - Master's Supervisor

Awards

Outstanding Postdoctoral Fellow: Zhejiang Province
Representative Postdoctoral Fellow: Zhejiang Province

Areas of Focus	Basic and clinical research on benign and malignant diseases of the liver, gallbladder, and pancreas Epigenetic regulation of the immune microenvironment and tumor metastasis Functional mechanisms of circular RNA in diseases
Publications	Cytoskeleton remodeling-mediated-by circRNA-YBX1 phase separation suppresses the metastasis of liver cancer, Liu Boqiang, Shen Hao, He Jing, Jin Binghan, Tian Tuanshi, Li Weiai, Hou Lidan, Zhao Weijun, Nan Junjie, Zhao Jia, Shen Jiliang, Yu Hong, Wang Yifan, Shan Ge, Shi Liang, Cai Xiujun, 2023 A tumor-suppressive circular RNA mediates uncanonical integrin degradation by the proteasome in liver cancer, Shi L, Liu B, Shen DD, Yan P, Zhang Y, Tian Y, Hou L, Jiang G, Zhu Y, Liang Y, Liang X, Shen B, Yu H, Zhang Y, Wang Y, Guo X, Cai X, 2021 Circular RNAs: characteristics, biogenesis, mechanisms and functions in liver cancer, Shen H, Liu B, Xu J, Zhang B, Wang Y, Shi L, Cai X, 2021 Cisplatin enhances NK cells immunotherapy efficacy to suppress HCC progression via altering the androgen receptor (AR)-ULBP2 signals, Shi L, Lin H, Li G, Sun Y, Shen J, Xu J, Lin C, Yeh S, Cai X, Chang C, 2016 Circular RNA expression is suppressed by androgen receptor (AR)-regulated adenosine deaminase that acts on RNA (ADAR1) in human hepatocellular carcinoma, Shi L, Yan P, Liang Y, Sun Y, Shen J, Zhou S, Lin H, Liang X, Cai X, 2017 Targeting Androgen Receptor (AR)→IL12A Signal Enhances Efficacy of Sorafenib plus NK Cells Immunotherapy to Better Suppress HCC Progression, Shi L, Lin H, Li G, Jin RA, Xu J, Sun Y, Ma WL, Yeh S, Cai X, Chang C, 2016 Role of estrogen in hepatocellular carcinoma: is inflammation the key?, Shi L, Feng Y, Lin H, Ma R, Cai X, 2014 Androgen receptor affects the response to immune checkpoint therapy by suppressing PD-L1 in hepatocellular carcinoma, Jiang G, Shi L, Zheng X, Zhang X, Wu K, Liu B, Yan P, Liang X, Yu T, Wang Y, Cai X, 2020 The role of natural killer cells in hepatocellular carcinoma development and treatment: A narrative review, Juengpanich S, Shi L, Iranmanesh Y, Chen J, Cheng Z, Khoo AK, Pan L, Wang Y, Cai X, 2019 The potential of mecciRNA in hepatic stellate cell to regulate progression of nonalcoholic hepatitis, Liu B, Tian Y, He J, Gu Q, Jin B, Shen H, Li W, Shi L, Yu H, Shan G, Cai X, 2022 Sorafenib with ASC-J9® synergistically suppresses the HCC progression via altering the pSTAT3-CCL2/Bcl2 signals, Xu J, Lin H, Li G, Sun Y, Shi L, Ma WL, Chen J, Cai X, Chang C, 2017 The miR-367-3p Increases Sorafenib Chemotherapy Efficacy to Suppress Hepatocellular Carcinoma Metastasis through Altering the Androgen Receptor Signals, Xu J, Lin H, Li G, Sun Y, Chen J, Shi L, Cai X, Chang C, 2016 CircUBAP2 Promotes MMP9-Mediated Oncogenic Effect via Sponging miR-194-3p in Hepatocellular Carcinoma, Liu B, Tian Y, Chen M, Shen H, Xia J, Nan J, Yan T, Wang Y, Shi L, Shen B, Yu H, Cai X, 2021 A retrospective pilot study to examine the feasibility of real-time navigation for laparoscopic liver resections in intrahepatic cholangiocarcinoma using fusion indocyanine green fluorescence imaging, Zhai ST, Liang X, Mao QJ, Liang YL, Xu JJ, Chen J, Shi L, Xie YY, Cai XJ, 2020 TR4 nuclear receptor suppresses HCC cell invasion via downregulating the EphA2 expression, Jin R, Lin H, Li G, Xu J, Shi L, Chang C, Cai X, 2018 Role of DUSP1/MKP1 in tumorigenesis, tumor progression and therapy, Shen J, Zhang Y, Yu H, Shen B, Liang Y, Jin R, Liu X, Shi L, Cai X, 2016

Areas of Focus

Basic and clinical research on benign and malignant diseases of the liver, gallbladder, and pancreas
Epigenetic regulation of the immune microenvironment and tumor metastasis
Functional mechanisms of circular RNA in diseases

Publications

Cytoskeleton remodeling-mediated-by circRNA-YBX1 phase separation suppresses the metastasis of liver cancer, Liu Boqiang, Shen Hao, He Jing, Jin Binghan, Tian Tuanshi, Li Weiai, Hou Lidan, Zhao Weijun, Nan Junjie, Zhao Jia, Shen Jiliang, Yu Hong, Wang Yifan, Shan Ge, Shi Liang, Cai Xiujun, 2023
A tumor-suppressive circular RNA mediates uncanonical integrin degradation by the proteasome in liver cancer, Shi L, Liu B, Shen DD, Yan P, Zhang Y, Tian Y, Hou L, Jiang G, Zhu Y, Liang Y, Liang X, Shen B, Yu H, Zhang Y, Wang Y, Guo X, Cai X, 2021
Circular RNAs: characteristics, biogenesis, mechanisms and functions in liver cancer, Shen H, Liu B, Xu J, Zhang B, Wang Y, Shi L, Cai X, 2021
Cisplatin enhances NK cells immunotherapy efficacy to suppress HCC progression via altering the androgen receptor (AR)-ULBP2 signals, Shi L, Lin H, Li G, Sun Y, Shen J, Xu J, Lin C, Yeh S, Cai X, Chang C, 2016
Circular RNA expression is suppressed by androgen receptor (AR)-regulated adenosine deaminase that acts on RNA (ADAR1) in human hepatocellular carcinoma, Shi L, Yan P, Liang Y, Sun Y, Shen J, Zhou S, Lin H, Liang X, Cai X, 2017
Targeting Androgen Receptor (AR)→IL12A Signal Enhances Efficacy of Sorafenib plus NK Cells Immunotherapy to Better Suppress HCC Progression, Shi L, Lin H, Li G, Jin RA, Xu J, Sun Y, Ma WL, Yeh S, Cai X, Chang C, 2016
Role of estrogen in hepatocellular carcinoma: is inflammation the key?, Shi L, Feng Y, Lin H, Ma R, Cai X, 2014
Androgen receptor affects the response to immune checkpoint therapy by suppressing PD-L1 in hepatocellular carcinoma, Jiang G, Shi L, Zheng X, Zhang X, Wu K, Liu B, Yan P, Liang X, Yu T, Wang Y, Cai X, 2020
The role of natural killer cells in hepatocellular carcinoma development and treatment: A narrative review, Juengpanich S, Shi L, Iranmanesh Y, Chen J, Cheng Z, Khoo AK, Pan L, Wang Y, Cai X, 2019
The potential of mecciRNA in hepatic stellate cell to regulate progression of nonalcoholic hepatitis, Liu B, Tian Y, He J, Gu Q, Jin B, Shen H, Li W, Shi L, Yu H, Shan G, Cai X, 2022
Sorafenib with ASC-J9® synergistically suppresses the HCC progression via altering the pSTAT3-CCL2/Bcl2 signals, Xu J, Lin H, Li G, Sun Y, Shi L, Ma WL, Chen J, Cai X, Chang C, 2017
The miR-367-3p Increases Sorafenib Chemotherapy Efficacy to Suppress Hepatocellular Carcinoma Metastasis through Altering the Androgen Receptor Signals, Xu J, Lin H, Li G, Sun Y, Chen J, Shi L, Cai X, Chang C, 2016
CircUBAP2 Promotes MMP9-Mediated Oncogenic Effect via Sponging miR-194-3p in Hepatocellular Carcinoma, Liu B, Tian Y, Chen M, Shen H, Xia J, Nan J, Yan T, Wang Y, Shi L, Shen B, Yu H, Cai X, 2021
A retrospective pilot study to examine the feasibility of real-time navigation for laparoscopic liver resections in intrahepatic cholangiocarcinoma using fusion indocyanine green fluorescence imaging, Zhai ST, Liang X, Mao QJ, Liang YL, Xu JJ, Chen J, Shi L, Xie YY, Cai XJ, 2020
TR4 nuclear receptor suppresses HCC cell invasion via downregulating the EphA2 expression, Jin R, Lin H, Li G, Xu J, Shi L, Chang C, Cai X, 2018
Role of DUSP1/MKP1 in tumorigenesis, tumor progression and therapy, Shen J, Zhang Y, Yu H, Shen B, Liang Y, Jin R, Liu X, Shi L, Cai X, 2016

Liver Gallbladder Pancreas Benign Malignant Epigenetic Immune Microenvironment Tumor Metastasis

Xueli Bai - Zhejiang University

Zhe Tang - Zhejiang University

Fangying Xu - Zhejiang University

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