Professor | Hongfei Xu | Asia Growth Partners

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Name	Hongfei Xu
Contact Information	xuhongfei@zju.edu.cn
Language ability	Chinese, English
Province	Zhejiang

Upload Avatar (500 x 500)

Name

Hongfei Xu

Contact Information

xuhongfei@zju.edu.cn

Language ability

Chinese, English

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Medical
Academic Background & Achievements	2018/09-2021/06 PhD in Clinical Medicine: Zhejiang University 2007/08-2014/06 Bachelor's and Master's in Clinical Medicine: Zhejiang University First author or corresponding author of 18 SCI papers Hosted 1 National Natural Science Foundation project Hosted 1 Provincial Natural Science Foundation project Received 1 National Invention Patent Received 3 Utility Model Patents
Work Experience	2023/01-Present - Zhejiang University, The First Affiliated Hospital, Department of Cardiovascular Surgery - Associate Chief Physician 2018/01-2022/12 - Zhejiang University, The First Affiliated Hospital, Department of Cardiovascular Surgery - Attending Physician 2014/08-2017/12 - Zhejiang University, The First Affiliated Hospital, Department of Cardiovascular Surgery - Resident Physician

University/Lab Affiliation and Title

Zhejiang University

Faculty

Medical

Academic Background & Achievements

2018/09-2021/06 PhD in Clinical Medicine: Zhejiang University
2007/08-2014/06 Bachelor's and Master's in Clinical Medicine: Zhejiang University
First author or corresponding author of 18 SCI papers
Hosted 1 National Natural Science Foundation project
Hosted 1 Provincial Natural Science Foundation project
Received 1 National Invention Patent
Received 3 Utility Model Patents

Work Experience

2023/01-Present - Zhejiang University, The First Affiliated Hospital, Department of Cardiovascular Surgery - Associate Chief Physician
2018/01-2022/12 - Zhejiang University, The First Affiliated Hospital, Department of Cardiovascular Surgery - Attending Physician
2014/08-2017/12 - Zhejiang University, The First Affiliated Hospital, Department of Cardiovascular Surgery - Resident Physician

Areas of Focus	Mechanisms and new treatment technologies for end-stage heart failure (heart transplantation and artificial heart implantation) Mechanisms and treatment progress of malignant cardiac tumors (biopsy/targeted therapy/immunotherapy) Interventional treatment of structural heart disease and development and application of new devices
Publications	GSTM2 alleviates heart failure by inhibiting DNA damage in cardiomyocytes., Xu H, Wang Z, Wang Y, Pan S, Zhao W, Chen M, Chen X, Tao T, Ma L, Ni Y, Li W., 2023 30-day outcomes of transcatheter tricuspid annuloplasty with the K-clip system: a single-center, observational study., Xu H, Li W, Lee AP, et al., 2023 Treatment of tricuspid valve prolapse using transcatheter tricuspid valve clip through the zip technique., Xu H, Zhu D, Ma L, Li W., 2023 Concomitant minimally invasive surgery for tricuspid valve papillary fibroelastoma and right lung cancer in an elderly patient: a case report and review of the literature., Wang Y, Saheb NABSA, Husanova F, Li W, Xu H (通讯)., 2023 Excision of left atrial myxoma under perfused ventricular fibrillation with hypothermia after coronary artery bypass grafting., Pan S, Wang Y, Gu Y, Li W, Xu H (通讯)., 2023 YTHDF2 alleviates cardiac hypertrophy via regulating Myh7 mRNA decoy., Xu H, Wang Z, Chen M, Zhao W, Tao T, Ma L, Ni Y, Li W., 2021 CCL24/CCR3 axis plays a central role in angiotensin II-induced heart failure by stimulating M2 macrophage polarization and fibroblast activation., Wang Z, Xu H, Chen M, Lu Y, Zheng L, Ma L., 2022 The impact of plasma vitamin C levels on the risk of cardiovascular diseases and Alzheimer's disease: A Mendelian randomization study., Chen L, Sun X, Wang Z, Lu Y, Chen M, He Y, Xu H, Zheng L., 2021 Gut microbes enlarged the protective effect of transplanted regulatory B cells on rejection of cardiac allografts., Li W, Wang D, Yue R, Chen X, Liu A, Xu H, Teng P, Wang Z, Zou Y, Xu X, Zhao H, Li R, Fu Y, Guo L, Ni C, Fan J, Ma L., 2021 M2c macrophages prevent atrial fibrillation in association with the inhibition of KCNQ1 in human embryonic stem cell-derived atrial-like cardiomyocytes., Sun Z, Ying X, Zhao W, He Y, Wang Z, Zheng L, Chen W, Xu H., 2021 Fibroblast Growth Factor 21 Protects Against Atrial Remodeling via Reducing Oxidative Stress., Chen M, Zhong J, Wang Z, Xu H, Chen H, Sun X, Lu Y, Chen L, Xie X, Zheng L., 2021 Concomitant surgery for aortic valve and lung cancer patients in an elder., Xu H, Tao T, Ma L, Li W, Ni Y., 2020 Modified band annuloplasty technique for functional tricuspid regurgitation repair in patients with grossly dilated annuli: The three-suture junctional continuous suture band annuloplasty technique., Xu H, Davies H, Zheng J, Peng T, Ni Y., 2019 Peri-cardiac surgery coagulation management in a severe hemophilia A patient: A case report., Xu H, Henry D, Li C, Zhao H, Yang Y., 2019 Three-dimensional visualization technology in coronary-pulmonary artery fistula., Xu H, Wang D, Li W, Ma L, Guo X, Ni Y., 2019 Right atrium hemangioma in patient with history of mixed-thrombus surgery., Zhao H, Tao T, Davies H, Lu Y, Xu H., 2019 Cardiac angiosarcoma: A case report and review of current treatment., Linfeng Q, Xingjie X, Henry D, Zhedong W, Hongfei X, Haige Z., 2019 GATA4 protects against hyperglycemia‑induced endothelial dysfunction by regulating NOX4 transcription., Xu H, Wang Z, Sun Z, Ni Y, Zheng L., 2018 Pressure Overload-induced Cardiac Hypertrophy Varies According to Different Ligation Needle Sizes and Body Weights in Mice., Jia Z, Chen Z, Xu H, Armah MA, Teng P, Li W, Jian D, Ma L, Ni Y., 2018 Cardiac Papillary Fibroelastoma with Coronary Artery Anomaly: A Case Report., Xu H, Chen L, Ye C, Owusu-Ansah KG, Ni Y, Li W., 2017 Cardiac haemangioma with coronary-pulmonary artery fistula in one patient., Xu H, Li W, Teng P, Ni Y., 2015 Case report of refractory pericardial effusion associated with lymphatic fistula due to surgical injury during sternotomy., Jiang L, Tao T, Zheng J, Jia Z, Xu H, Ni Y., 2018 Case report of pulmonary epithelial trophoblastic tumor in a young female patient., Jiang L, Xu H, Lu Y, Li W, Zheng C., 2017 Inhibition of AMPK-related kinase 5 (ARK5) enhances cisplatin cytotoxicity in non-small cell lung cancer cells through regulation of epithelial-mesenchymal transition., Li M, Zheng C, Xu H, He W, Ruan Y, Ma J, Zheng J, Ye C, Li W., 2017 Cross-talk between macrophages and atrial myocytes in atrial fibrillation., Sun Z, Zhou D, Xie X, Wang S, Wang Z, Zhao W, Xu H, Zheng L., 2016 miR-223/FBW7 axis regulates doxorubicin sensitivity through epithelial mesenchymal transition in non-small cell lung cancer., Li R, Wu S, Chen X, Xu H, Teng P, Li W., 2016 Beating-heart surgical treatment of tricuspid valve papillary fibroelastoma: A case report., Li W, Zheng J, Zhao H, Xu H, Ni Y., 2016 Cardiac hypertrophy and dysfunction induced by overexpression of miR-214 in vivo., Yang T, Gu H, Chen X, Fu S, Wang C, Xu H, Feng Q, Ni Y., 2014 MicroRNA-214 provokes cardiac hypertrophy via repression of EZH2., Yang T, Zhang GF, Chen XF, Gu HH, Fu SZ, Xu HF, Feng Q, Ni YM., 2013 Primary giant cardiac cavernous hemangioma in right mediastinum., Li W, Chen X, Xu H, Li B, Kong M, Ma L, Ni Y., 2013 Complete excision of a giant thyroid goiter in posterior mediastinum., Chen X, Xu H, Ni Y, Sun K, Li W., 2013 A huge mediastinal space-occupying lesion., Guo L, Xu H, Ni Y, Feng Q., 2013 Cardiac Hemangioma: A Comprehensive Analysis of 200 Cases., Li W, Teng P, Xu H, Ma L, Ni Y., 2015 Extracorporeal membrane oxygenation treatment of a H7N9-caused respiratory failure patient with mechanical valves replacement history: A case report., Qian L, Zheng J, Xu H, Shi L, Li L., 2016 A trick to control the bleeding in cardiovascular surgery., Ni YM, Altangerel B, Xu HF, Zhao HG., 2015

Areas of Focus

Mechanisms and new treatment technologies for end-stage heart failure (heart transplantation and artificial heart implantation)
Mechanisms and treatment progress of malignant cardiac tumors (biopsy/targeted therapy/immunotherapy)
Interventional treatment of structural heart disease and development and application of new devices

Publications

GSTM2 alleviates heart failure by inhibiting DNA damage in cardiomyocytes., Xu H, Wang Z, Wang Y, Pan S, Zhao W, Chen M, Chen X, Tao T, Ma L, Ni Y, Li W., 2023
30-day outcomes of transcatheter tricuspid annuloplasty with the K-clip system: a single-center, observational study., Xu H, Li W, Lee AP, et al., 2023
Treatment of tricuspid valve prolapse using transcatheter tricuspid valve clip through the zip technique., Xu H, Zhu D, Ma L, Li W., 2023
Concomitant minimally invasive surgery for tricuspid valve papillary fibroelastoma and right lung cancer in an elderly patient: a case report and review of the literature., Wang Y, Saheb NABSA, Husanova F, Li W, Xu H (通讯)., 2023
Excision of left atrial myxoma under perfused ventricular fibrillation with hypothermia after coronary artery bypass grafting., Pan S, Wang Y, Gu Y, Li W, Xu H (通讯)., 2023
YTHDF2 alleviates cardiac hypertrophy via regulating Myh7 mRNA decoy., Xu H, Wang Z, Chen M, Zhao W, Tao T, Ma L, Ni Y, Li W., 2021
CCL24/CCR3 axis plays a central role in angiotensin II-induced heart failure by stimulating M2 macrophage polarization and fibroblast activation., Wang Z, Xu H, Chen M, Lu Y, Zheng L, Ma L., 2022
The impact of plasma vitamin C levels on the risk of cardiovascular diseases and Alzheimer's disease: A Mendelian randomization study., Chen L, Sun X, Wang Z, Lu Y, Chen M, He Y, Xu H, Zheng L., 2021
Gut microbes enlarged the protective effect of transplanted regulatory B cells on rejection of cardiac allografts., Li W, Wang D, Yue R, Chen X, Liu A, Xu H, Teng P, Wang Z, Zou Y, Xu X, Zhao H, Li R, Fu Y, Guo L, Ni C, Fan J, Ma L., 2021
M2c macrophages prevent atrial fibrillation in association with the inhibition of KCNQ1 in human embryonic stem cell-derived atrial-like cardiomyocytes., Sun Z, Ying X, Zhao W, He Y, Wang Z, Zheng L, Chen W, Xu H., 2021
Fibroblast Growth Factor 21 Protects Against Atrial Remodeling via Reducing Oxidative Stress., Chen M, Zhong J, Wang Z, Xu H, Chen H, Sun X, Lu Y, Chen L, Xie X, Zheng L., 2021
Concomitant surgery for aortic valve and lung cancer patients in an elder., Xu H, Tao T, Ma L, Li W, Ni Y., 2020
Modified band annuloplasty technique for functional tricuspid regurgitation repair in patients with grossly dilated annuli: The three-suture junctional continuous suture band annuloplasty technique., Xu H, Davies H, Zheng J, Peng T, Ni Y., 2019
Peri-cardiac surgery coagulation management in a severe hemophilia A patient: A case report., Xu H, Henry D, Li C, Zhao H, Yang Y., 2019
Three-dimensional visualization technology in coronary-pulmonary artery fistula., Xu H, Wang D, Li W, Ma L, Guo X, Ni Y., 2019
Right atrium hemangioma in patient with history of mixed-thrombus surgery., Zhao H, Tao T, Davies H, Lu Y, Xu H., 2019
Cardiac angiosarcoma: A case report and review of current treatment., Linfeng Q, Xingjie X, Henry D, Zhedong W, Hongfei X, Haige Z., 2019
GATA4 protects against hyperglycemia‑induced endothelial dysfunction by regulating NOX4 transcription., Xu H, Wang Z, Sun Z, Ni Y, Zheng L., 2018
Pressure Overload-induced Cardiac Hypertrophy Varies According to Different Ligation Needle Sizes and Body Weights in Mice., Jia Z, Chen Z, Xu H, Armah MA, Teng P, Li W, Jian D, Ma L, Ni Y., 2018
Cardiac Papillary Fibroelastoma with Coronary Artery Anomaly: A Case Report., Xu H, Chen L, Ye C, Owusu-Ansah KG, Ni Y, Li W., 2017
Cardiac haemangioma with coronary-pulmonary artery fistula in one patient., Xu H, Li W, Teng P, Ni Y., 2015
Case report of refractory pericardial effusion associated with lymphatic fistula due to surgical injury during sternotomy., Jiang L, Tao T, Zheng J, Jia Z, Xu H, Ni Y., 2018
Case report of pulmonary epithelial trophoblastic tumor in a young female patient., Jiang L, Xu H, Lu Y, Li W, Zheng C., 2017
Inhibition of AMPK-related kinase 5 (ARK5) enhances cisplatin cytotoxicity in non-small cell lung cancer cells through regulation of epithelial-mesenchymal transition., Li M, Zheng C, Xu H, He W, Ruan Y, Ma J, Zheng J, Ye C, Li W., 2017
Cross-talk between macrophages and atrial myocytes in atrial fibrillation., Sun Z, Zhou D, Xie X, Wang S, Wang Z, Zhao W, Xu H, Zheng L., 2016
miR-223/FBW7 axis regulates doxorubicin sensitivity through epithelial mesenchymal transition in non-small cell lung cancer., Li R, Wu S, Chen X, Xu H, Teng P, Li W., 2016
Beating-heart surgical treatment of tricuspid valve papillary fibroelastoma: A case report., Li W, Zheng J, Zhao H, Xu H, Ni Y., 2016
Cardiac hypertrophy and dysfunction induced by overexpression of miR-214 in vivo., Yang T, Gu H, Chen X, Fu S, Wang C, Xu H, Feng Q, Ni Y., 2014
MicroRNA-214 provokes cardiac hypertrophy via repression of EZH2., Yang T, Zhang GF, Chen XF, Gu HH, Fu SZ, Xu HF, Feng Q, Ni YM., 2013
Primary giant cardiac cavernous hemangioma in right mediastinum., Li W, Chen X, Xu H, Li B, Kong M, Ma L, Ni Y., 2013
Complete excision of a giant thyroid goiter in posterior mediastinum., Chen X, Xu H, Ni Y, Sun K, Li W., 2013
A huge mediastinal space-occupying lesion., Guo L, Xu H, Ni Y, Feng Q., 2013
Cardiac Hemangioma: A Comprehensive Analysis of 200 Cases., Li W, Teng P, Xu H, Ma L, Ni Y., 2015
Extracorporeal membrane oxygenation treatment of a H7N9-caused respiratory failure patient with mechanical valves replacement history: A case report., Qian L, Zheng J, Xu H, Shi L, Li L., 2016
A trick to control the bleeding in cardiovascular surgery., Ni YM, Altangerel B, Xu HF, Zhao HG., 2015

Heart Failure Heart Transplantation Artificial Heart Cardiac Tumors Biopsy Targeted Therapy Immunotherapy Structural Heart Disease Interventional Treatment Device Development

Weidong Li - Zhejiang University

Cai Zhejun - Zhejiang University

Yu-Ping Shi - Zhejiang University

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