Professor | Kesong Peng | Asia Growth Partners

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Name	Kesong Peng
Contact Information	kesongpeng@zju.edu.cn
Language ability	Chinese, English
Province	Zhejiang

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Name

Kesong Peng

Contact Information

kesongpeng@zju.edu.cn

Language ability

Chinese, English

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Medical
Academic Background & Achievements	2015.09-2018.12 PhD in Cell Biology: Xiamen University 2011.09-2014.06 Master's in Traditional Chinese Medicine: Wenzhou Medical University 2007.09-2011.07 Bachelor's in Pharmacy: Anhui Medical University
Work Experience	2023.01-Present - Zhejiang University - Distinguished Researcher 2019.01-2022.12 - Fudan University - Postdoctoral Researcher

University/Lab Affiliation and Title

Zhejiang University

Faculty

Medical

Academic Background & Achievements

2015.09-2018.12 PhD in Cell Biology: Xiamen University
2011.09-2014.06 Master's in Traditional Chinese Medicine: Wenzhou Medical University
2007.09-2011.07 Bachelor's in Pharmacy: Anhui Medical University

Work Experience

2023.01-Present - Zhejiang University - Distinguished Researcher
2019.01-2022.12 - Fudan University - Postdoctoral Researcher

Areas of Focus	Role of selective autophagy of organelles in maintaining cellular homeostasis and metabolic reprogramming in tumor development Molecular mechanisms of protein post-translational modification machinery in maintaining organelle homeostasis Screening of receptors and ligands based on lysosome-targeted protein degradation
Publications	Demethylase JMJD2D induces PD-L1 expression to promote colorectal cancer immune escape by enhancing IFNGR1-STAT3-IRF1 signaling, Qiang Chen, Shuqing Zhuang, Yilin Hong, Lingtao Yang, Peng Guo, Pingli Mo, Kesong Peng, Wengang Li, Nengming Xiao, Chundong Yu, 2022 Nuclear receptor coactivator SRC-1 promotes colorectal cancer progression through enhancing GLI2-mediated Hedgehog signaling, Peng Guo, Qiang Chen, Kesong Peng, Jianyuan Xie, Junjia Liu, Wenjing Ren, Zhangwei Tong, Ming Li, Jianming Xu, Yongyou Zhang, Chundong Yu, Pingli Mo, 2022 Histone demethylase JMJD2D activates HIF1 signaling pathway via multiple mechanisms to promote colorectal cancer glycolysis and progression, Kesong Peng, Minghui Zhuo, Ming Li, Qiang Chen, Pingli Mo, Chundong Yu, 2020 Histone Demethylase JMJD2D Interacts With Beta-catenin to Induce Transcription of Target Genes and Activate Colorectal Cancer Cell Proliferation and Tumor Growth in Mice, Kesong Peng, Lele Kou, Li Yu, Chaonan Bai, Ming Li, Pingli Mo, Wengang Li, Chundong Yu, 2019 Histone demethylase JMJD1A promotes colorectal cancer growth and metastasis by enhancing Wnt/β-catenin signaling, Kesong Peng, Guoqiang Su, Jinmeng Ji, Xiaojia Yang, Mengmeng Miao, Pingli Mo, Ming Li, Jianming Xu, Wengang Li, Chundong Yu, 2018 Histone demethylase JMJD1A promotes urinary bladder cancer progression by enhancing glycolysis through coactivation of hypoxia inducible factor 1α, Wei Wan, Kesong Peng, Ming Li, Liping Qin, Zhangwei Tong, Jun Yan, Bin Shen, Chundong Yu, 2017 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) Mediates Insulin Resistance through JNK Activation in Adipocytes, Kesong Peng, Yong Pan, Jieli Li, Zia Khan, Mendi Fan, Haimin Yin, Chao Tong, Yunjie Zhao, Guang Liang, Chao Zheng, 2016 Novel EGFR inhibitors attenuate cardiac hypertrophy induced by angiotensin II, Kesong Peng, Xinqiao Tian, Yuanyuan Qian, Melissa Skibba, Chunpeng Zou, Zhiguo Liu, Jingying Wang, Zheng Xu, Xiaokun Li, Guang Liang, 2016 Novel Epidermal Growth Factor Receptor Inhibitor Attenuates Angiotensin II-Induced Kidney Fibrosis, Yuanyuan Qian, Kesong Peng, Chenyu Qiu, Melissa Skibba, Yi Huang, Zheng Xu, Yali Zhang, Jie Hu, Dandan Liang, Chunpeng Zou, Yi Wang, Guang Liang, 2016

Areas of Focus

Role of selective autophagy of organelles in maintaining cellular homeostasis and metabolic reprogramming in tumor development
Molecular mechanisms of protein post-translational modification machinery in maintaining organelle homeostasis
Screening of receptors and ligands based on lysosome-targeted protein degradation

Publications

Demethylase JMJD2D induces PD-L1 expression to promote colorectal cancer immune escape by enhancing IFNGR1-STAT3-IRF1 signaling, Qiang Chen, Shuqing Zhuang, Yilin Hong, Lingtao Yang, Peng Guo, Pingli Mo, Kesong Peng, Wengang Li, Nengming Xiao, Chundong Yu, 2022
Nuclear receptor coactivator SRC-1 promotes colorectal cancer progression through enhancing GLI2-mediated Hedgehog signaling, Peng Guo, Qiang Chen, Kesong Peng, Jianyuan Xie, Junjia Liu, Wenjing Ren, Zhangwei Tong, Ming Li, Jianming Xu, Yongyou Zhang, Chundong Yu, Pingli Mo, 2022
Histone demethylase JMJD2D activates HIF1 signaling pathway via multiple mechanisms to promote colorectal cancer glycolysis and progression, Kesong Peng, Minghui Zhuo, Ming Li, Qiang Chen, Pingli Mo, Chundong Yu, 2020
Histone Demethylase JMJD2D Interacts With Beta-catenin to Induce Transcription of Target Genes and Activate Colorectal Cancer Cell Proliferation and Tumor Growth in Mice, Kesong Peng, Lele Kou, Li Yu, Chaonan Bai, Ming Li, Pingli Mo, Wengang Li, Chundong Yu, 2019
Histone demethylase JMJD1A promotes colorectal cancer growth and metastasis by enhancing Wnt/β-catenin signaling, Kesong Peng, Guoqiang Su, Jinmeng Ji, Xiaojia Yang, Mengmeng Miao, Pingli Mo, Ming Li, Jianming Xu, Wengang Li, Chundong Yu, 2018
Histone demethylase JMJD1A promotes urinary bladder cancer progression by enhancing glycolysis through coactivation of hypoxia inducible factor 1α, Wei Wan, Kesong Peng, Ming Li, Liping Qin, Zhangwei Tong, Jun Yan, Bin Shen, Chundong Yu, 2017
11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) Mediates Insulin Resistance through JNK Activation in Adipocytes, Kesong Peng, Yong Pan, Jieli Li, Zia Khan, Mendi Fan, Haimin Yin, Chao Tong, Yunjie Zhao, Guang Liang, Chao Zheng, 2016
Novel EGFR inhibitors attenuate cardiac hypertrophy induced by angiotensin II, Kesong Peng, Xinqiao Tian, Yuanyuan Qian, Melissa Skibba, Chunpeng Zou, Zhiguo Liu, Jingying Wang, Zheng Xu, Xiaokun Li, Guang Liang, 2016
Novel Epidermal Growth Factor Receptor Inhibitor Attenuates Angiotensin II-Induced Kidney Fibrosis, Yuanyuan Qian, Kesong Peng, Chenyu Qiu, Melissa Skibba, Yi Huang, Zheng Xu, Yali Zhang, Jie Hu, Dandan Liang, Chunpeng Zou, Yi Wang, Guang Liang, 2016

Autophagy Organelle Homeostasis Metabolic Reprogramming Tumor Development Protein Modification Lysosome Protein Degradation Receptors Ligands

Wei Liu - Zhejiang University

Qiming Sun - Zhejiang University

Wei Chen - Zhejiang University

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