Professor | Xiurong Wu | Asia Growth Partners

	Upload Avatar (500 x 500)
Name	Xiurong Wu
Contact Information	xiurongwu@zju.edu.cn
Language ability	English, Chinese
Province	Zhejiang

Upload Avatar (500 x 500)

Name

Xiurong Wu

Contact Information

xiurongwu@zju.edu.cn

Language ability

English, Chinese

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Medical
Academic Background & Achievements	PhD and Postdoctoral training: Han Jiahuai's lab 2023: Joined the First Affiliated Hospital of Zhejiang University School of Medicine as a Distinguished Researcher Published 8 papers as first author, co-first author, or co-corresponding author in high-level journals such as Immunity, Cell Mol Immunol, Mol Cell Proteomics, PLoS Pathog Published 7 papers as a co-author in high-level journals such as Nat Methods, Mol Cell, PNAS Hosted National Natural Science Foundation Youth Science Fund project and Postdoctoral General Grant
Work Experience	2023 - Present: First Affiliated Hospital of Zhejiang University School of Medicine - Distinguished Researcher

University/Lab Affiliation and Title

Zhejiang University

Faculty

Medical

Academic Background & Achievements

PhD and Postdoctoral training: Han Jiahuai's lab
2023: Joined the First Affiliated Hospital of Zhejiang University School of Medicine as a Distinguished Researcher
Published 8 papers as first author, co-first author, or co-corresponding author in high-level journals such as Immunity, Cell Mol Immunol, Mol Cell Proteomics, PLoS Pathog
Published 7 papers as a co-author in high-level journals such as Nat Methods, Mol Cell, PNAS
Hosted National Natural Science Foundation Youth Science Fund project and Postdoctoral General Grant

Work Experience

2023 - Present: First Affiliated Hospital of Zhejiang University School of Medicine - Distinguished Researcher

Areas of Focus	Natural immune signal transduction and its function in diseases
Publications	Bypassing PELO-mediated ATPase activation of the NLR is a common pathogenic cause of NLR-associated autoinflammatory diseases, Wu, X.# , Yang, Z. H.#, Zheng,Y., Wu, J., Han, J., 2024 Ribosome-rescuer PELO catalyzes the oligomeric assembly of NOD-like receptor family proteins via activating their ATPase enzymatic activity, Wu, X.# , Yang, Z. H.#, Wu, J., Han, J., 2023 Evaluation of DDA Library-Free Strategies for Phosphoproteomics and Ubiquitinomics Data-Independent Acquisition Data, Wen, C. #, Wu, X.# , Lin, G.#, Yan, W., Gan, G., Xu, X., Xiang-Yu Chen, X. Y., Chen, X., Liu, X., Fu, G., Zhong, C. Q., 2023 Protocol for reconstitution of oligomeric assembly of NAIP5-NLRC4 inflammasome in vitro, Wu, X., Han, J., 2023 RIP1-dependent linear and nonlinear recruitments of caspase-8 and RIP3 respectively to necrosome specify distinct cell death outcomes, Li, X.#, Zhong, C. Q.#, Wu, R.#, Xu, X., Yang, Z.H., Cai, S., Wu, X., Chen, X., Yin, Z., He, Q., Li, D., Xu, F., Yan, Y., Qi, H., Xie, C., Shuai, J., Han, J., 2021 A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-mediated Necroptosis-Blockade, Yang, Z. H.#, Wu, X. N.#, He, P.#, Wang, X., Wu, J., Ai, T., Zhong, C. Q., Wu, X., Cong, Y., Zhu, R., Li, H., Cai, Z. Y., Mo, W., Han, J., 2020 Quantification of Dynamic Protein Interactions and Phosphorylation in LPS Signaling Pathway by SWATH-MS, Wu, X., Yang, D., Zhao, F., Yang, Z. H., Wang, D., Qiao, M., Fang, Y., Li, W., Wu, R., He, P., Cong, Y., Chen, C., Hu, L., Yan, Y., Xie, C., Wu, Y., Han, J., Zhong, C. Q., 2019 Group-DIA: analyzing multiple data-independent acquisition mass spectrometry data files, Li, Y.#, Zhong, C. Q.# , Xu, X., Cai, S., Wu, X., Zhang, Y., Chen, J., Shi, J., Lin, S., Han, J., 2015 The p38 pathway regulates oxidative stress tolerance by phosphorylation of mitochondrial protein IscU, Tian, L., Chen, J., Chen, M., Gui, C., Zhong, C. Q., Hong, L., Xie, C., Wu, X., Yang, L., Ahmad, V., Han, J., 2014 pelo is required for high efficiency viral replication, Wu, X., He, W. T., Tian, S., Meng, D., Li, Y., Chen, W., Li, L., Tian, L., Zhong, C. Q., Han, F., Chen, J., Han, J., 2014 A potential suppressive effect of natural antisense IL-1beta RNA on lipopolysaccharide-induced IL-1beta expression, Lu, J.#, Wu, X.#, Hong, M., Tobias, P., and Han, J., 2013 Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling, Chen, W.#, Zhou, Z.#, Li, L.#, Zhong, C. Q., Zheng, X., Wu, X., Zhang, Y., Ma, H., Huang, D., Li, W., Xia, Z., and Han, J. , 2013 Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics, Wu, X.#, Tian, L.#, Li, J., Zhang, Y., Han, V., Li, Y., Xu, X., Li, H., Chen, X., Chen, J., Jin, W., Xie, Y., Han, J., and Zhong, C. Q., 2012 Participation of the p38 pathway in Drosophila host defense against pathogenic bacteria and fungi, Chen, J., Xie, C., Tian, L., Hong, L., Wu, X., and Han, J., 2010 Epithelial p38alpha controls immune cell recruitment in the colonic mucosa, Kang, Y. J.#, Otsuka, M.#, van den Berg, A., Hong, L., Huang, Z., Wu, X., Zhang, D. W., Vallance, B. A., Tobias, P. S., Han, J. , 2010

Areas of Focus

Natural immune signal transduction and its function in diseases

Publications

Bypassing PELO-mediated ATPase activation of the NLR is a common pathogenic cause of NLR-associated autoinflammatory diseases, Wu, X.# *, Yang, Z. H.#, Zheng,Y., Wu, J., Han, J.*, 2024
Ribosome-rescuer PELO catalyzes the oligomeric assembly of NOD-like receptor family proteins via activating their ATPase enzymatic activity, Wu, X.# *, Yang, Z. H.#, Wu, J., Han, J.*, 2023
Evaluation of DDA Library-Free Strategies for Phosphoproteomics and Ubiquitinomics Data-Independent Acquisition Data, Wen, C. #, Wu, X.# *, Lin, G.#, Yan, W., Gan, G., Xu, X., Xiang-Yu Chen, X. Y., Chen, X., Liu, X., Fu, G.*, Zhong, C. Q.*, 2023
Protocol for reconstitution of oligomeric assembly of NAIP5-NLRC4 inflammasome in vitro, Wu, X.*, Han, J.*, 2023
RIP1-dependent linear and nonlinear recruitments of caspase-8 and RIP3 respectively to necrosome specify distinct cell death outcomes, Li, X.#, Zhong, C. Q.#, Wu, R.#, Xu, X., Yang, Z.H., Cai, S., Wu, X., Chen, X., Yin, Z., He, Q., Li, D., Xu, F., Yan, Y., Qi, H., Xie, C., Shuai, J.*, Han, J.*, 2021
A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-mediated Necroptosis-Blockade, Yang, Z. H.#, Wu, X. N.#, He, P.#, Wang, X., Wu, J., Ai, T., Zhong, C. Q., Wu, X., Cong, Y., Zhu, R., Li, H., Cai, Z. Y., Mo, W.*, Han, J.*, 2020
Quantification of Dynamic Protein Interactions and Phosphorylation in LPS Signaling Pathway by SWATH-MS, Wu, X., Yang, D., Zhao, F., Yang, Z. H., Wang, D., Qiao, M., Fang, Y., Li, W., Wu, R., He, P., Cong, Y., Chen, C., Hu, L., Yan, Y., Xie, C., Wu, Y., Han, J.*, Zhong, C. Q.*, 2019
Group-DIA: analyzing multiple data-independent acquisition mass spectrometry data files, Li, Y.#, Zhong, C. Q.# *, Xu, X., Cai, S., Wu, X., Zhang, Y., Chen, J., Shi, J., Lin, S., Han, J.*, 2015
The p38 pathway regulates oxidative stress tolerance by phosphorylation of mitochondrial protein IscU, Tian, L., Chen, J.*, Chen, M., Gui, C., Zhong, C. Q., Hong, L., Xie, C., Wu, X., Yang, L., Ahmad, V., Han, J.*, 2014
pelo is required for high efficiency viral replication, Wu, X., He, W. T., Tian, S., Meng, D., Li, Y., Chen, W., Li, L., Tian, L., Zhong, C. Q., Han, F., Chen, J., Han, J.*, 2014
A potential suppressive effect of natural antisense IL-1beta RNA on lipopolysaccharide-induced IL-1beta expression, Lu, J.#, Wu, X.#, Hong, M., Tobias, P., and Han, J.*, 2013
Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling, Chen, W.#, Zhou, Z.#, Li, L.#, Zhong, C. Q., Zheng, X., Wu, X., Zhang, Y., Ma, H., Huang, D., Li, W., Xia, Z., and Han, J. *, 2013
Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics, Wu, X.#, Tian, L.#, Li, J., Zhang, Y., Han, V., Li, Y., Xu, X., Li, H., Chen, X., Chen, J., Jin, W., Xie, Y., Han, J.*, and Zhong, C. Q.*, 2012
Participation of the p38 pathway in Drosophila host defense against pathogenic bacteria and fungi, Chen, J., Xie, C., Tian, L., Hong, L., Wu, X., and Han, J.*, 2010
Epithelial p38alpha controls immune cell recruitment in the colonic mucosa, Kang, Y. J.#, Otsuka, M.#, van den Berg, A., Hong, L., Huang, Z., Wu, X., Zhang, D. W., Vallance, B. A., Tobias, P. S., Han, J. *, 2010

Immune System Signal Transduction Disease Inflammation Nlr Atpase Autoinflammatory Diseases Ribosome-Rescuer Pelo Nod-Like Receptor

Jun Zhou - Zhejiang University

Xia Meng - Zhejiang University

Wenyan Cui - Zhejiang University

View All

Personal Information

Academic Information

Research

Contact us

No account yet?

Personal Information

Academic Information

Research

Contact us