Areas of Focus
- Gene delivery and gene therapy
- Intracellular delivery of proteins and peptides
- Polymer transformation medicine
- Medical hydrogel materials
Work Experience
- 2009.02-2009.10: Postdoctoral Researcher at Washington University in St. Louis
- 2010.03-present: Professor and Doctoral Supervisor at East China Normal University, School of Life Sciences
Academic Background & Achievements
- 1997-2000: High School at Jiangsu Province Jiangyan High School
- 2000-2004: Bachelor in Polymer Science and Engineering, University of Science and Technology of China
- 2004-2008: PhD in Life Sciences, University of Science and Technology of China
Publications
- A general strategy towards personalized nanovaccines based on fluoropolymers for post-surgical cancer immunotherapy, Xu J, Lv J, Zhuang Q, Yang Z, Cao Z, Xu L, Pei P, Wang C, Wu H, Dong Z, Chao Y, Wang C, Yang K, Peng R*, Cheng YY*, Liu Z*, 2020
- Bifunctional and bioreducible dendrimer bearing a fluoroalkyl tail for efficient protein delivery both in vitro and in vivo, Lv J., Wang C, Li H, Li Z, Fan Q, Zhang Y, Li Y. Wang H*, Cheng YY*, 2020
- Fluoroalkylation promotes cytosolic peptide delivery, Rong GY, Wang CP, Chen LJ, Yan Y, Cheng YY*, 2020
- Natural Polyphenol Inspired Polycatechols for Efficient siRNA Delivery, Shen W, Wang R, Fan Q, Gao X, Wang H, Shen Y, Li YW*, Cheng YY*, 2020
- A Coordinative Dendrimer Achieves Excellent Efficiency in Cytosolic Protein and Peptide Delivery, Ren L, Lv J, Wang H, Cheng YY*, 2020
- A Boronic acid-rich Dendrimer with Robust and Unprecedented Efficiency for Cytosolic Protein Delivery and CRISPR-Cas9 Gene Editing, Liu CY, Wang T, Wang H, Zhang S, Ping Y*, Cheng YY*, 2019
- Off-On Switching of Enzyme Activity by Near-infrared Light-Induced Photothermal Phase Transition of Nanohybrids, Zhang S, Wang CP, Chang H, Zhang Q*, Cheng YY*, 2019
- The Fluorination Effect of Fluoroamphiphiles in Cytosolic Protein Delivery, Zhang ZJ, Shen WW, Ling J, Yan Y, Hu JJ, Cheng YY*, 2018
- Green Tea Catechin Dramatically Promotes RNAi Mediated by Low Molecular Weight Polymers, Shen W, Wang Q, Shen Y, Gao X, Li L, Yan Y, Wang H, Cheng YY*, 2018
- Foe to Friend: Supramolecular Nanomedicines Consisting of Natural Polyphenols and Bortezomib, Wang CP, Sang H, Wang Y, Zhu F, Hu X, Wang X, Wang X, Li Y*, Cheng YY*, 2018
- Dynamic Modulation of Enzyme Activity by Near-infrared Light, Wang CP, Zhang Q, Wang X, Chang H, Zhang S, Tang Y, Xu J, Qi R, Cheng YY*, 2017
- Rational Design of a Polymer with Robust Efficacy for Intracellular Protein and Peptide Delivery, Chang H, Lv J, Gao X, Wang X, Wang H, Chen H, He X, Li L, Cheng YY*, 2017
- Dendrimer-templated Ultrasmall and Multifunctional Photothermal Agents for Efficient Tumor Ablation, Zhou ZJ, Wang YT, Yan Y, Zhang Q*, Cheng YY*, 2016
- Surface-engineered Dendrimers in Gene Delivery, Yang JP, Zhang Q, Chang H, Cheng YY*, 2015
- Self-assembled Fluorodendrimers Combine the Features of Lipid and Polymeric Vectors in Gene Delivery, Wang H, Wang YT, Wang Y, Li TF, Liu HM, Zhang Q, Cheng YY*, 2015
- A Fluorinated Dendrimer Achieves Excellent Gene Transfection Efficiency at Extremely Low Nitrogen to Phosphorus Ratios, Wang MM, Liu HM, Li Lei, Cheng YY*, 2014
- Glutathione-triggered \"Off-on\" Release of Anticancer Drugs from Dendrimer-encapsulated Gold Nanoparticles, Liu HM, Wang H, Yang WJ, Cheng YY*, 2013
- NMR Insights into Dendrimer-based Host-guest Systems, Hu JJ, Xu TW, Cheng YY*, 2012
- Design of Biocompatible Dendrimers for Cancer Diagnosis and Therapy: Current Status and Future Perspectives, Zhao LB, Wu QL, Cheng YY*, Zhang JH, Wu JH, Xu TW*, 2011
- High-throughput Screening of Dendrimer-binding Drugs, Yavuz MS, Cheng YY, Chen JY, Cobley CM, Zhang Q, Rycenga M, Xie JW, Kim C, Schwartz AG, Wang LV, Xia YN*, 2009
Awards
- 2019: Young Chemist Award from the Chinese Chemical Society
- 2017: National Science Fund for Distinguished Young Scholars
- 2016: Shanghai Youth May Fourth Medal
- 2015: Shanghai Outstanding Academic Leader
- 2013: Shanghai Youth Science and Technology Star
