Professor | Yiyun Cheng | Asia Growth Partners

Name	Yiyun Cheng
Contact Information	yycheng@mail.ustc.edu.cn
Language ability	Chinese, English
Province	Shanghai

Name

Yiyun Cheng

Contact Information

yycheng@mail.ustc.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	East China Normal University
Faculty	Life Sciences
Academic Background & Achievements	1997-2000: High School at Jiangsu Province Jiangyan High School 2000-2004: Bachelor in Polymer Science and Engineering, University of Science and Technology of China 2004-2008: PhD in Life Sciences, University of Science and Technology of China
Work Experience	2009.02-2009.10: Postdoctoral Researcher at Washington University in St. Louis 2010.03-present: Professor and Doctoral Supervisor at East China Normal University, School of Life Sciences
Awards	2019: Young Chemist Award from the Chinese Chemical Society 2017: National Science Fund for Distinguished Young Scholars 2016: Shanghai Youth May Fourth Medal 2015: Shanghai Outstanding Academic Leader 2013: Shanghai Youth Science and Technology Star

University/Lab Affiliation and Title

East China Normal University

Faculty

Life Sciences

Academic Background & Achievements

1997-2000: High School at Jiangsu Province Jiangyan High School
2000-2004: Bachelor in Polymer Science and Engineering, University of Science and Technology of China
2004-2008: PhD in Life Sciences, University of Science and Technology of China

Work Experience

2009.02-2009.10: Postdoctoral Researcher at Washington University in St. Louis
2010.03-present: Professor and Doctoral Supervisor at East China Normal University, School of Life Sciences

Awards

2019: Young Chemist Award from the Chinese Chemical Society
2017: National Science Fund for Distinguished Young Scholars
2016: Shanghai Youth May Fourth Medal
2015: Shanghai Outstanding Academic Leader
2013: Shanghai Youth Science and Technology Star

Areas of Focus	Gene delivery and gene therapy Intracellular delivery of proteins and peptides Polymer transformation medicine Medical hydrogel materials
Publications	A general strategy towards personalized nanovaccines based on fluoropolymers for post-surgical cancer immunotherapy, Xu J, Lv J, Zhuang Q, Yang Z, Cao Z, Xu L, Pei P, Wang C, Wu H, Dong Z, Chao Y, Wang C, Yang K, Peng R, Cheng YY, Liu Z, 2020 Bifunctional and bioreducible dendrimer bearing a fluoroalkyl tail for efficient protein delivery both in vitro and in vivo, Lv J., Wang C, Li H, Li Z, Fan Q, Zhang Y, Li Y. Wang H, Cheng YY, 2020 Fluoroalkylation promotes cytosolic peptide delivery, Rong GY, Wang CP, Chen LJ, Yan Y, Cheng YY, 2020 Natural Polyphenol Inspired Polycatechols for Efficient siRNA Delivery, Shen W, Wang R, Fan Q, Gao X, Wang H, Shen Y, Li YW, Cheng YY, 2020 A Coordinative Dendrimer Achieves Excellent Efficiency in Cytosolic Protein and Peptide Delivery, Ren L, Lv J, Wang H, Cheng YY, 2020 A Boronic acid-rich Dendrimer with Robust and Unprecedented Efficiency for Cytosolic Protein Delivery and CRISPR-Cas9 Gene Editing, Liu CY, Wang T, Wang H, Zhang S, Ping Y, Cheng YY, 2019 Off-On Switching of Enzyme Activity by Near-infrared Light-Induced Photothermal Phase Transition of Nanohybrids, Zhang S, Wang CP, Chang H, Zhang Q, Cheng YY, 2019 The Fluorination Effect of Fluoroamphiphiles in Cytosolic Protein Delivery, Zhang ZJ, Shen WW, Ling J, Yan Y, Hu JJ, Cheng YY, 2018 Green Tea Catechin Dramatically Promotes RNAi Mediated by Low Molecular Weight Polymers, Shen W, Wang Q, Shen Y, Gao X, Li L, Yan Y, Wang H, Cheng YY, 2018 Foe to Friend: Supramolecular Nanomedicines Consisting of Natural Polyphenols and Bortezomib, Wang CP, Sang H, Wang Y, Zhu F, Hu X, Wang X, Wang X, Li Y, Cheng YY, 2018 Dynamic Modulation of Enzyme Activity by Near-infrared Light, Wang CP, Zhang Q, Wang X, Chang H, Zhang S, Tang Y, Xu J, Qi R, Cheng YY, 2017 Rational Design of a Polymer with Robust Efficacy for Intracellular Protein and Peptide Delivery, Chang H, Lv J, Gao X, Wang X, Wang H, Chen H, He X, Li L, Cheng YY, 2017 Dendrimer-templated Ultrasmall and Multifunctional Photothermal Agents for Efficient Tumor Ablation, Zhou ZJ, Wang YT, Yan Y, Zhang Q, Cheng YY, 2016 Surface-engineered Dendrimers in Gene Delivery, Yang JP, Zhang Q, Chang H, Cheng YY, 2015 Self-assembled Fluorodendrimers Combine the Features of Lipid and Polymeric Vectors in Gene Delivery, Wang H, Wang YT, Wang Y, Li TF, Liu HM, Zhang Q, Cheng YY, 2015 A Fluorinated Dendrimer Achieves Excellent Gene Transfection Efficiency at Extremely Low Nitrogen to Phosphorus Ratios, Wang MM, Liu HM, Li Lei, Cheng YY, 2014 Glutathione-triggered \"Off-on\" Release of Anticancer Drugs from Dendrimer-encapsulated Gold Nanoparticles, Liu HM, Wang H, Yang WJ, Cheng YY, 2013 NMR Insights into Dendrimer-based Host-guest Systems, Hu JJ, Xu TW, Cheng YY, 2012 Design of Biocompatible Dendrimers for Cancer Diagnosis and Therapy: Current Status and Future Perspectives, Zhao LB, Wu QL, Cheng YY, Zhang JH, Wu JH, Xu TW, 2011 High-throughput Screening of Dendrimer-binding Drugs, Yavuz MS, Cheng YY, Chen JY, Cobley CM, Zhang Q, Rycenga M, Xie JW, Kim C, Schwartz AG, Wang LV, Xia YN*, 2009

Areas of Focus

Gene delivery and gene therapy
Intracellular delivery of proteins and peptides
Polymer transformation medicine
Medical hydrogel materials

Publications

A general strategy towards personalized nanovaccines based on fluoropolymers for post-surgical cancer immunotherapy, Xu J, Lv J, Zhuang Q, Yang Z, Cao Z, Xu L, Pei P, Wang C, Wu H, Dong Z, Chao Y, Wang C, Yang K, Peng R*, Cheng YY*, Liu Z*, 2020
Bifunctional and bioreducible dendrimer bearing a fluoroalkyl tail for efficient protein delivery both in vitro and in vivo, Lv J., Wang C, Li H, Li Z, Fan Q, Zhang Y, Li Y. Wang H*, Cheng YY*, 2020
Fluoroalkylation promotes cytosolic peptide delivery, Rong GY, Wang CP, Chen LJ, Yan Y, Cheng YY*, 2020
Natural Polyphenol Inspired Polycatechols for Efficient siRNA Delivery, Shen W, Wang R, Fan Q, Gao X, Wang H, Shen Y, Li YW*, Cheng YY*, 2020
A Coordinative Dendrimer Achieves Excellent Efficiency in Cytosolic Protein and Peptide Delivery, Ren L, Lv J, Wang H, Cheng YY*, 2020
A Boronic acid-rich Dendrimer with Robust and Unprecedented Efficiency for Cytosolic Protein Delivery and CRISPR-Cas9 Gene Editing, Liu CY, Wang T, Wang H, Zhang S, Ping Y*, Cheng YY*, 2019
Off-On Switching of Enzyme Activity by Near-infrared Light-Induced Photothermal Phase Transition of Nanohybrids, Zhang S, Wang CP, Chang H, Zhang Q*, Cheng YY*, 2019
The Fluorination Effect of Fluoroamphiphiles in Cytosolic Protein Delivery, Zhang ZJ, Shen WW, Ling J, Yan Y, Hu JJ, Cheng YY*, 2018
Green Tea Catechin Dramatically Promotes RNAi Mediated by Low Molecular Weight Polymers, Shen W, Wang Q, Shen Y, Gao X, Li L, Yan Y, Wang H, Cheng YY*, 2018
Foe to Friend: Supramolecular Nanomedicines Consisting of Natural Polyphenols and Bortezomib, Wang CP, Sang H, Wang Y, Zhu F, Hu X, Wang X, Wang X, Li Y*, Cheng YY*, 2018
Dynamic Modulation of Enzyme Activity by Near-infrared Light, Wang CP, Zhang Q, Wang X, Chang H, Zhang S, Tang Y, Xu J, Qi R, Cheng YY*, 2017
Rational Design of a Polymer with Robust Efficacy for Intracellular Protein and Peptide Delivery, Chang H, Lv J, Gao X, Wang X, Wang H, Chen H, He X, Li L, Cheng YY*, 2017
Dendrimer-templated Ultrasmall and Multifunctional Photothermal Agents for Efficient Tumor Ablation, Zhou ZJ, Wang YT, Yan Y, Zhang Q*, Cheng YY*, 2016
Surface-engineered Dendrimers in Gene Delivery, Yang JP, Zhang Q, Chang H, Cheng YY*, 2015
Self-assembled Fluorodendrimers Combine the Features of Lipid and Polymeric Vectors in Gene Delivery, Wang H, Wang YT, Wang Y, Li TF, Liu HM, Zhang Q, Cheng YY*, 2015
A Fluorinated Dendrimer Achieves Excellent Gene Transfection Efficiency at Extremely Low Nitrogen to Phosphorus Ratios, Wang MM, Liu HM, Li Lei, Cheng YY*, 2014
Glutathione-triggered \"Off-on\" Release of Anticancer Drugs from Dendrimer-encapsulated Gold Nanoparticles, Liu HM, Wang H, Yang WJ, Cheng YY*, 2013
NMR Insights into Dendrimer-based Host-guest Systems, Hu JJ, Xu TW, Cheng YY*, 2012
Design of Biocompatible Dendrimers for Cancer Diagnosis and Therapy: Current Status and Future Perspectives, Zhao LB, Wu QL, Cheng YY*, Zhang JH, Wu JH, Xu TW*, 2011
High-throughput Screening of Dendrimer-binding Drugs, Yavuz MS, Cheng YY, Chen JY, Cobley CM, Zhang Q, Rycenga M, Xie JW, Kim C, Schwartz AG, Wang LV, Xia YN*, 2009

Gene Therapy Gene Delivery Biomolecular Delivery Polymer Medicine Hydrogels Biomedical Engineering Nanotechnology Drug Delivery Biocompatibility Therapeutics

Jianglin Wang - Huazhong University of Science and Technology

Xiangliang Yang - Huazhong University of Science and Technology

Lu Xiaoyun - Xi'an Jiaotong University

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