Professor | Jiwen Li | Asia Growth Partners

Name	Jiwen Li
Contact Information	jiwenster@gmail.com
Language ability	English, Chinese
Province	Shanghai

Name

Jiwen Li

Contact Information

jiwenster@gmail.com

Language ability

English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	East China Normal University
Faculty	Life Sciences
Academic Background & Achievements	1986-1990 Bachelor of Science in Biochemistry: Fudan University 1995-1997 Master of Science in Biomedical Science: Hood College, USA, Supervisor: Dr. Yun-Bo Shi
Work Experience	1997/8-2007/5 - Baylor College of Medicine, USA - Senior Research Assistant 2007/9 - Present - East China Normal University, School of Life Sciences - Senior Engineer

University/Lab Affiliation and Title

East China Normal University

Faculty

Life Sciences

Academic Background & Achievements

1986-1990 Bachelor of Science in Biochemistry: Fudan University
1995-1997 Master of Science in Biomedical Science: Hood College, USA, Supervisor: Dr. Yun-Bo Shi

Work Experience

1997/8-2007/5 - Baylor College of Medicine, USA - Senior Research Assistant
2007/9 - Present - East China Normal University, School of Life Sciences - Senior Engineer

Areas of Focus	Research on DNA methylation, histone modification, and nucleosome remodeling in chromatin structure and function Study of gene expression regulation mechanisms using nuclear hormone receptors as a model Research on the molecular mechanisms of SUMO modification inhibiting transcription and the role and mechanism of SUMO-binding nucleosomes in transcription regulation
Publications	SET8 prevents excessive DNA methylation by methylation-mediated degradation of UHRF1 and DNMT1, Zhang, Huifang; Gao, Qinqin; Tan, Shuo; You, Jia; Lyu, Cong; Zhang, Yunpeng; Han, Mengmeng; Chen, Zhaosu; Li, Jialun; Wang, Hailin; Liao, Lujian; Qin, Jun; Li, Jiwen; Wong, Jiemin, 2019 SUMOylation down-regulates rDNA transcription by repressing expression of upstream-binding factor and proto-oncogene c-Myc, Peng, Yu; Wang, Zhenxing; Wang, Zhiqiang; Yu, Fang; Li, Jiwen; Wong, Jiemin, 2019 Activated MEK/ERK Pathway Drives Widespread and Coordinated Overexpression of UHRF1 and DNMT1 in Cancer cells, Li, Jialun; Wang, Ruiping; Hu, Xueli; Gao, Yingying; Wang, Zhen; Li, Jiwen; Wong, Jiemin, 2019 SUMO suppresses and MYC amplifies transcription globally by regulating CDK9 sumoylation, Yu, Fang; Shi, Guang; Cheng, Shimeng; Chen, Jiwei; Wu, Shwu Yuan; Wang, Zhiqiang; Xia, Nansong; Zhai, Yunhao; Wang, Zhenxing; Peng, Yu; Wang, Dong; Du, James X; Liao, Lujian; Duan, Sheng Zhong; Shi, Tieliu; Cheng, Jinke; Chiang, Cheng Ming; Li, Jiwen; Wong, Jiemin, 2018 MOF as an evolutionarily conserved histone crotonyltransferase and transcriptional activation by histone acetyltransferase-deficient and crotonyltransferase-competent CBP/p300, Liu Xiaoguang; Wei Wei; Liu Yuting; Yang Xueli; Wu Jian; Zhang Yang; Zhang Qiao; Shi Tieliu; Du James X; Zhao Yingming; Lei Ming; Zhou Jin Qiu; Li Jiwen; Wong Jiemin, 2017

Areas of Focus

Research on DNA methylation, histone modification, and nucleosome remodeling in chromatin structure and function
Study of gene expression regulation mechanisms using nuclear hormone receptors as a model
Research on the molecular mechanisms of SUMO modification inhibiting transcription and the role and mechanism of SUMO-binding nucleosomes in transcription regulation

Publications

SET8 prevents excessive DNA methylation by methylation-mediated degradation of UHRF1 and DNMT1, Zhang, Huifang; Gao, Qinqin; Tan, Shuo; You, Jia; Lyu, Cong; Zhang, Yunpeng; Han, Mengmeng; Chen, Zhaosu; Li, Jialun; Wang, Hailin; Liao, Lujian; Qin, Jun; Li, Jiwen*; Wong, Jiemin*, 2019
SUMOylation down-regulates rDNA transcription by repressing expression of upstream-binding factor and proto-oncogene c-Myc, Peng, Yu; Wang, Zhenxing; Wang, Zhiqiang; Yu, Fang; Li, Jiwen*; Wong, Jiemin*, 2019
Activated MEK/ERK Pathway Drives Widespread and Coordinated Overexpression of UHRF1 and DNMT1 in Cancer cells, Li, Jialun; Wang, Ruiping; Hu, Xueli; Gao, Yingying; Wang, Zhen; Li, Jiwen*; Wong, Jiemin*, 2019
SUMO suppresses and MYC amplifies transcription globally by regulating CDK9 sumoylation, Yu, Fang; Shi, Guang; Cheng, Shimeng; Chen, Jiwei; Wu, Shwu Yuan; Wang, Zhiqiang; Xia, Nansong; Zhai, Yunhao; Wang, Zhenxing; Peng, Yu; Wang, Dong; Du, James X; Liao, Lujian; Duan, Sheng Zhong; Shi, Tieliu; Cheng, Jinke; Chiang, Cheng Ming; Li, Jiwen*; Wong, Jiemin*, 2018
MOF as an evolutionarily conserved histone crotonyltransferase and transcriptional activation by histone acetyltransferase-deficient and crotonyltransferase-competent CBP/p300, Liu Xiaoguang; Wei Wei; Liu Yuting; Yang Xueli; Wu Jian; Zhang Yang; Zhang Qiao; Shi Tieliu; Du James X; Zhao Yingming; Lei Ming; Zhou Jin Qiu; Li Jiwen*; Wong Jiemin*, 2017

Dna Methylation Histone Modification Nucleosome Remodeling Chromatin Structure Gene Expression Nuclear Hormone Receptors Sumo Modification Transcription Inhibition Sumo-Binding Nucleosomes Transcription Regulation

Jiang Cizhong - Tongji University

Jianfeng Chang - Tongji University

Jiemin Weng - East China Normal University

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