Areas of Focus
- Genetic diseases: Clinical challenges, lack of effective treatments for most known genetic diseases, high impact on families and society, especially children.
- Gene therapy: Development and application challenges, potential in treating genetic diseases, recent market introductions of gene therapy products.
Work Experience
- 2009-2014 - East China Normal University, Promoted from Associate Professor to Researcher
- Current - Director at Shanghai Frontiers Science Research Base for Gene Editing and Cell Therapy
- Current - Deputy Director at Shanghai Key Laboratory of Regulatory Biology
- Current - Director at Minhang Experimental Animal Center, East China Normal University
Academic Background & Achievements
- 2007 - PhD in Genetics, Hunan Normal University
- Joint research at Texas A&M University during PhD
- Recipient of the 'Outstanding Youth Fund'
Publications
- Non-viral, specifically targeted CAR-T cells achieve high safety and efficacy in B-NHL, Zhang J, Hu Y, Yang J, Li W, Zhang M, Wang Q, Zhang L, Wei G, Tian Y, Zhao K, Chen A, Tan B, Cui J, Li D, Li Y, Qi Y, Wang D, Wu Y, Li D, Du B, Liu M, Huang H, 2022
- CRISPR-Cas9-mediated gene editing of the BCL11A enhancer for pediatric β0/β0 transfusion-dependent β-thalassemia, Fu B, Liao J, Chen S, Li W, Wang Q, Hu J, Yang F, Hsiao S, Jiang Y, Wang L, Chen F, Zhang Y, Wang X, Li D, Liu M, Wu Y, 2022
Awards
- 2018 - First Prize in Natural Science Award from the Ministry of Education (Ranked second)
- 2018 - Second Prize in Science and Technology Progress Award from Hainan Province (Ranked fourth)
