Zhang Wei
Life Science
East China Normal University
Shanghai
Language: Chinese, English
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Adamts18 Development Cardiovascular Diseases Metalloproteinase Gene Knockout Zebrafish Model Transcriptomics Proteomics Molecular Biology Tumor Mechanisms Anti-Platelet Therapy Cancer Treatment Mechanisms Platelets Therapeutic Strategies Clinical Applications Research Pharmacology Molecular Targets
Areas of Focus
  • Role of metalloproteinase ADAMTS18 in development and cardiovascular diseases
  • Mechanisms of anti-platelet therapy in cardiovascular diseases and cancer treatment
Work Experience
  • 2006-2010 - New York University Medical School, Postdoctoral Researcher in Hematology/Oncology
  • 2010.5-present - East China Normal University, Faculty Member
Academic Background & Achievements
  • 2005 - PhD in Biochemistry and Molecular Biology from Nanjing University
  • Published over 30 papers as first or corresponding author
  • Applied for 4 national patents, 1 granted
Publications
  • A humanized single-chain antibody against beta 3 integrin inhibits pulmonary metastasis by preferentially fragmenting activated platelets in the tumor microenvironment., Zhang W, Dang S, Hong T, Tang J, Fan J, Bu D, Sun Y, Wang Z, Wisniewski T., 2012
  • Dissolution of arterial platelet thrombi in vivo with a bifunctional platelet GPIIIa49-66 ligand which specifically targets the platelet thrombus., Zhang W, Li YS, Nardi M, Dang S, Yang J, Ji Y, Li Z, Karpatkin S, Wisniewski T., 2010
  • Role of molecular mimickry of hepatitis C (HCV) protein with platelet GPIIIa in hepatitis C-related thrombocytopenia., Zhang W, Nardi MA, Borkowsky W, Li Z, Karpatkin S., 2009
Awards
  • Chinese Federation of Medical Education Award
  • Travel Award at the American Society of Hematology Annual Meeting
  • The GERALD WEISSMANN AWARD at New York University
  • Shanghai Pujiang Talent (A) Class
  • Shanghai Meiji Life Science Award
  • Chinese Overseas Contribution Award
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