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Changmei Liu
Institute of Zoology
Chinese Academy of Sciences
Beijing
Language: Chinese, English
Chromatin
Neural Development
Neural Injury
Repair Mechanisms
Neural Precursor Cells
Differentiation
Stem Cell Therapy
Translational Research
Molecular Mechanisms
Neurodegenerative Diseases
Areas of Focus
- Chromatin dynamics in neural development
- Mechanisms of neural injury repair
- Directed differentiation of human neural precursor cells
- Translational research in stem cell therapy
Work Experience
- 2004-2008 - Assistant Researcher and Associate Researcher at Institute of Microbiology, Chinese Academy of Sciences
- 2008-2015 - Postdoctoral Research at University of New Mexico and Johns Hopkins University
- 2015-present - Researcher at Institute of Zoology, Chinese Academy of Sciences
Academic Background & Achievements
- 2004 - PhD in Biochemistry and Molecular Biology: Peking Union Medical College
- Published research in top journals like Cell Stem Cell, Nature Neuroscience
Publications
- Telomerase Reverse Transcriptase and p53 Regulate Mammalian Peripheral Nervous System and CNS Axon Regeneration Downstream of c-Myc, Ma JJ, Ju X, Xu RJ, Wang WH, Luo ZP, Liu CM, Zhou FQ, Saijilafu, 2019
- Calcium/calmodulin-dependent protein kinase II regulates mammalian axon growth by affecting F-actin length in growth cone, Xi F, Xu RJ, Xu JH, Ma JJ, Wang WH, Liu CM, Yang HL, Meng B, Saijilafu, 2019
- The Role of Non-Coding RNAs in Neurodevelopmental Disorders, Zhang SF, Gao J, Liu CM, 2019
- MiR-137 Deficiency Causes Anxiety-Like Behaviors in Mice, Yan HL, Sun XW, Wang ZM, Liu PP, Mi TW, Liu C, Wang YY, He XC, Du HZ, Liu CM, Teng ZQ, 2019
- Regulatory Networks between Polycomb Complexes and Non-coding RNAs in Central Nervous System, Xu YJ, Liu PP, Ng SC, Teng ZQ, Liu CM, 2019
- GA-binding protein GABPβ1 is required for the proliferation of neural stem/progenitor cells, Liu C, Dai SK, Sun Z, Wang Z, Liu PP, Du HZ, Yu S, Liu CM, Teng ZQ, 2019
- Polycomb Protein EED Regulates Neuronal Differentiation through Targeting SOX11 in Hippocampal Dentate Gyrus, Liu PP, Xu YJ, Dai SK, Du HZ, Wang YY, Li XG, Teng ZQ, Liu CM, 2019
- Partial loss of psychiatric risk gene Mir137 in mice causes repetitive behavior and impairs sociability and learning via increased Pde10a, Cheng Y, Wang ZM, Tan W, Wang X, Li Y, Bai B, Li Y, Zhang SF, Yan HL, Chen ZL, Liu CM, Mi TW, Xia S, et al., 2018
- Polycomb protein family member CBX7 regulates intrinsic axon growth and regeneration, Duan RS, Tang GB, Du HZ, Hu YW, Liu PP, Xu YJ, Zeng YQ, Zhang SF, Wang RY, Teng ZQ, Liu CM, 2018
- Polycomb Repressive Complex 2: Emerging Roles in the Central Nervous System, Liu PP, Xu YJ, Teng ZQ, Liu CM, 2018
- The histone h3k27 demethylase utx regulates synaptic plasticity and cognitive behaviors in mice, Tang GB, Zeng YQ, Liu PP, Mi TW, Zhang SF, Dai SK, Tang QY, Yang L, Xu YJ, Yan HL, Du HZ, Teng ZQ, Zhou FQ, Liu CM, 2017
- MiR-203 Interplays with polycomb repressive complexes to regulate the proliferation of neural stem/progenitor cells, Liu PP, Tang GB, Xu YJ, Zeng YQ, Zhang SF, Du HZ, Teng ZQ, Liu CM, 2017
- Extrinsic and intrinsic regulation of axon regeneration by micrornas after spinal cord injury, Li P, Teng ZQ, Liu CM, 2016
- MicroRNA-26a supports mammalian axon regeneration in vivo by suppressing GSK3β expression, Jiang JJ, Liu CM, Zhang BY, Wang XW, Zhang M, Saijilafu, Zhang SR, Hall P, Hu YW, Zhou FQ, 2015
- MicroRNA-138 and SIRT1 form a mutual negative feedback loop to regulate mammalian axon regeneration, Liu CM, Wang RY, Saijilafu, Jiao ZX, Zhang BY, Zhou FQ, 2013
- Epigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferation and differentiation, Liu CM, Teng ZQ, Santistevan NJ, Szulwach KE, Guo W, Jin P, Zhao X, 2010
- PI3K-GSK3 pathway regulates mammalian axon regeneration by induction of Smad1, Saijilafu, Hur EM, Liu CM, Jiao ZX, Xu WL, and Zhou F-Q, 2013
- RNA binding protein FXR2 regulates proliferation and differentiation of adult hippocampal neural stem cells by repressing Noggin expression, Guo W, Zhang Li, Christopher DM, Teng ZQ, Fausett SR, Liu CM, George OL, Klingensmith J, Jin P, Zhao X, 2011
- An Epigenetic Feedback Regulatory Loop Involving MicroRNA-195 and MBD1 Governs Neural Stem Cell Differentiation, Liu CM, Teng ZQ, McQuate AL, Jobe EM, Christ CC, Hoyningen-Huene SJ, Reyes MD, Polich ED, Xing Y, Li Y, Guo W, Zhao X, 2013
- Inhibition of atrogin-1/MAFbx expression by adenovirus-delivered small hairpin RNAs attenuates muscle atrophy in fasting mice, Cong HL, Sun LQ, Liu C, Tien P, 2011
- Epigenetic regulation of the stem cell mitogen Fgf-2 by Mbd1 in adult neural stem/progenitor cells, Li X, Barkho BZ, Luo Y, Smrt RD, Santistevan NJ, Liu C, Kuwabara T, Gage FH, Zhao X, 2008
- Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells, Luo Y, Shan G, Guo W, Smrt RD, Johnson EB, Li X, Pfeiffer RL, Szulwach KE, Duan R, Barkho BZ, Li W, Liu C, Jin P, Zhao X, 2010
- MicroRNAs in adult and embryonic neurogenesis, Liu CM, Zhao XY, 2009
- Myostatin antisense RNA-mediated muscle growth in normal and cancer cachexia mice, Liu CM, Yang Z, Liu CW, Wang R, Tien P, Dale R, Sun LQ, 2008
- The role of small RNAs in human diseases: potential troublemaker and therapeutic tools, Gong H, Liu CM, Liu DP, Liang CC, 2005
- MicroRNAs: key participants in gene regulatory networks, Ke XS, Liu CM, Liu DP, Liang CC, 2003
