Professor | Jin Xin | Asia Growth Partners

Name	Jin Xin
Contact Information	xjin@bio.ecnu.edu.cn
Language ability	Chinese, English
Province	Shanghai

Name

Jin Xin

Contact Information

xjin@bio.ecnu.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	East China Normal University
Faculty	Life Sciences
Academic Background & Achievements	1998-2002 Bachelor: China Agricultural University 2002-2007 PhD: Shanghai Jiao Tong University
Work Experience	2008-2011 - National Institutes of Health, USA - Postdoctoral Researcher 2012-2017 - Salk Institute for Biological Studies, USA - Assistant Professor 2018-2020 - Salk Institute for Biological Studies, USA - Associate Professor 2021-present - East China Normal University, China - Distinguished Professor and Director
Awards	NIH Lasker Award Society for Neuroscience Gruber International Research Award McKnight Memory and Cognitive Disorders Award

University/Lab Affiliation and Title

East China Normal University

Faculty

Life Sciences

Academic Background & Achievements

1998-2002 Bachelor: China Agricultural University
2002-2007 PhD: Shanghai Jiao Tong University

Work Experience

2008-2011 - National Institutes of Health, USA - Postdoctoral Researcher
2012-2017 - Salk Institute for Biological Studies, USA - Assistant Professor
2018-2020 - Salk Institute for Biological Studies, USA - Associate Professor
2021-present - East China Normal University, China - Distinguished Professor and Director

Awards

NIH Lasker Award
Society for Neuroscience Gruber International Research Award
McKnight Memory and Cognitive Disorders Award

Areas of Focus	Neural circuits Motor control Brain-machine interfaces
Publications	Secondary auditory cortex mediates a sensorimotor mechanism for action timing, Cook JR, Li H, Nguyen B, Huang HH, Mahdavian P, Kirchgessner MA, Strassmann P, Engelhardt M, Callaway EM, Jin X, 2022 Epigenomic diversity of cortical projection neurons in the mouse brain, Zhang Z, Zhou J, Tan P, Pang Y, Rivkin AC, Kirchgessner MA, Williams E, Lee CT, Liu H, Franklin AD, Miyazaki PA, Bartlett A, Aldridge AI, Vu M, Boggeman L, Fitzpatrick C, Nery JR, Castanon RG, Rashid M, Jacobs MW, Ito-Cole T, O'Connor C, Pinto-Duartec A, Dominguez B, Smith JB, Niu SY, Lee KF, Jin X, Mukamel EA, Behrens MM, Ecker JR, Callaway EM, 2021 Nigrostriatal dopamine signals sequence-specific action-outcome prediction errors, Hollon NG, Williams EW, Howard CD, Li H, Traut TI, Jin X, 2021 VTA glutamate neuron activity drives positive reinforcement absent dopamine co-release, Zell V, Steinkellner T, Hollon NG, Warlow SM, Souter E, Faget L, Hunker AC, Jin X, Zweifel LS, Hnasko TS, 2020 Neural implementation of behavioral hierarchy, Hollon NG, Jin X, 2020 An open cortico-basal ganglia loop allows limbic control over motor output via the nigrothalamic pathway, Aoki S, Smith JB, Li H, Yan X, Igarashi M, Coulon P, Wickens JR, Ruigrok TJ, Jin X, 2019 Optogenetic editing reveals the hierarchical organization of learned action sequences, Geddes CE, Li H, Jin X, 2018 Differential inputs to striatal cholinergic and parvalbumin interneurons imply functional distinctions, Klug JR, Engelhardt MD, Cadman CN, Li H, Smith JB, Ayala S, Williams EW, Hoffman H, Jin X, 2018 An in vivo model of functional and vascularized human brain organoids, Mansour AA, Gonçalves JT, Bloyd CW, Li H, Fernandes S, Quang D, Johnston S, Parylak SL, Jin X, Gage FH, 2018 Dynamic nigrostriatal dopamine biases action selection, Howard CD, Li H, Geddes CE, Jin X, 2017 Genetic-based dissection unveils the inputs and outputs of striatal patch and matrix compartments, Smith JB, Klug JR, Ross DL, Howard CD, Hollon NG, Ko VI, Hoffman H, Callaway EM, Gerfen CR, Jin X, 2016 Complementary contributions of striatal projection pathways to action initiation and execution, Tecuapetla F, Jin X, Lima SQ, Costa RM, 2016 Loss of motoneuron-specific microRNA-218 causes systemic neuromuscular failure, Amin ND, Bai G, Klug JR, Bonanomi D, Pankratz MT, Gifford WD, Hinckley CA, Sternfeld MJ, Driscoll SP, Dominguez B, Lee KF, Jin X, Pfaff SL, 2015 Corticostriatal dynamics encode the refinement of specific behavioral variability during skill learning, Santos FJ, Oliveira RF, Jin X, Costa RM, 2015 Shaping action sequences in basal ganglia circuits, Jin X, Costa RM, 2015 Basal ganglia subcircuits distinctively encode the parsing and concatenation of action sequences, Jin X, Tecuapetla F, Costa RM, 2014 Concurrent activation of striatal direct and indirect pathways during action initiation, Cui G, Jun SB, Jin X, Pham MD, Vogel SS, Lovinger DM, Costa RM, 2013 An aetiological Foxp2 mutation causes aberrant striatal activity and alters plasticity during skill learning, French CA, Jin X, Campbell TG, Gerfen E, Groszer M, Fisher SE, Costa RM, 2012 Corticostriatal plasticity is necessary for learning intentional neuroprosthetic skills, Koralek AC, Jin X, Long JD, Costa RM, Carmena JM, 2012 Start/stop signals emerge in nigrostriatal circuits during sequence learning, Jin X, Costa RM, 2010

Areas of Focus

Neural circuits
Motor control
Brain-machine interfaces

Publications

Secondary auditory cortex mediates a sensorimotor mechanism for action timing, Cook JR, Li H, Nguyen B, Huang HH, Mahdavian P, Kirchgessner MA, Strassmann P, Engelhardt M, Callaway EM, Jin X, 2022
Epigenomic diversity of cortical projection neurons in the mouse brain, Zhang Z, Zhou J, Tan P, Pang Y, Rivkin AC, Kirchgessner MA, Williams E, Lee CT, Liu H, Franklin AD, Miyazaki PA, Bartlett A, Aldridge AI, Vu M, Boggeman L, Fitzpatrick C, Nery JR, Castanon RG, Rashid M, Jacobs MW, Ito-Cole T, O'Connor C, Pinto-Duartec A, Dominguez B, Smith JB, Niu SY, Lee KF, Jin X, Mukamel EA, Behrens MM, Ecker JR, Callaway EM, 2021
Nigrostriatal dopamine signals sequence-specific action-outcome prediction errors, Hollon NG, Williams EW, Howard CD, Li H, Traut TI, Jin X, 2021
VTA glutamate neuron activity drives positive reinforcement absent dopamine co-release, Zell V, Steinkellner T, Hollon NG, Warlow SM, Souter E, Faget L, Hunker AC, Jin X, Zweifel LS, Hnasko TS, 2020
Neural implementation of behavioral hierarchy, Hollon NG, Jin X, 2020
An open cortico-basal ganglia loop allows limbic control over motor output via the nigrothalamic pathway, Aoki S, Smith JB, Li H, Yan X, Igarashi M, Coulon P, Wickens JR, Ruigrok TJ, Jin X, 2019
Optogenetic editing reveals the hierarchical organization of learned action sequences, Geddes CE, Li H, Jin X, 2018
Differential inputs to striatal cholinergic and parvalbumin interneurons imply functional distinctions, Klug JR, Engelhardt MD, Cadman CN, Li H, Smith JB, Ayala S, Williams EW, Hoffman H, Jin X, 2018
An in vivo model of functional and vascularized human brain organoids, Mansour AA, Gonçalves JT, Bloyd CW, Li H, Fernandes S, Quang D, Johnston S, Parylak SL, Jin X, Gage FH, 2018
Dynamic nigrostriatal dopamine biases action selection, Howard CD, Li H, Geddes CE, Jin X, 2017
Genetic-based dissection unveils the inputs and outputs of striatal patch and matrix compartments, Smith JB, Klug JR, Ross DL, Howard CD, Hollon NG, Ko VI, Hoffman H, Callaway EM, Gerfen CR, Jin X, 2016
Complementary contributions of striatal projection pathways to action initiation and execution, Tecuapetla F, Jin X, Lima SQ, Costa RM, 2016
Loss of motoneuron-specific microRNA-218 causes systemic neuromuscular failure, Amin ND, Bai G, Klug JR, Bonanomi D, Pankratz MT, Gifford WD, Hinckley CA, Sternfeld MJ, Driscoll SP, Dominguez B, Lee KF, Jin X, Pfaff SL, 2015
Corticostriatal dynamics encode the refinement of specific behavioral variability during skill learning, Santos FJ, Oliveira RF, Jin X, Costa RM, 2015
Shaping action sequences in basal ganglia circuits, Jin X, Costa RM, 2015
Basal ganglia subcircuits distinctively encode the parsing and concatenation of action sequences, Jin X, Tecuapetla F, Costa RM, 2014
Concurrent activation of striatal direct and indirect pathways during action initiation, Cui G, Jun SB, Jin X, Pham MD, Vogel SS, Lovinger DM, Costa RM, 2013
An aetiological Foxp2 mutation causes aberrant striatal activity and alters plasticity during skill learning, French CA, Jin X, Campbell TG, Gerfen E, Groszer M, Fisher SE, Costa RM, 2012
Corticostriatal plasticity is necessary for learning intentional neuroprosthetic skills, Koralek AC, Jin X, Long JD, Costa RM, Carmena JM, 2012
Start/stop signals emerge in nigrostriatal circuits during sequence learning, Jin X, Costa RM, 2010

Neural Circuits Motor Control Brain-Machine Interfaces Basal Ganglia Neurophysiology Optogenetics Behavioral Science Cognitive Disorders Neurogenetics Electrophysiology

Jin Xin - East China Normal University

Zhang Jiping - East China Normal University

Jiada Li - Central South University

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