Professor | Lei Liu | Asia Growth Partners

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Name	Lei Liu
Contact Information	liulei@ioz.ac.cn
Language ability	Chinese, English
Province	Beijing

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Name

Lei Liu

Contact Information

liulei@ioz.ac.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Chinese Academy of Sciences
Faculty	Institute of Zoology
Academic Background & Achievements	Identified a new mammalian mitophagy receptor protein FUNDC1 Published over 30 SCI papers First or corresponding author in journals like Nature Cell Biology, EMBO Journal
Work Experience	Researcher at the State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences
Awards	Lu Jiaxi Young Talent Award (2014)

University/Lab Affiliation and Title

Chinese Academy of Sciences

Faculty

Institute of Zoology

Academic Background & Achievements

Identified a new mammalian mitophagy receptor protein FUNDC1
Published over 30 SCI papers
First or corresponding author in journals like Nature Cell Biology, EMBO Journal

Work Experience

Researcher at the State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences

Awards

Lu Jiaxi Young Talent Award (2014)

Areas of Focus	Regulation of mitochondrial and other organelle homeostasis and disease
Publications	Defective mitochondrial ISCs biogenesis switches on IRP1 to fine tune selective mitophagy, Wu H, Wei H, Zhang D, Sehgal SA, Zhang D, Wang X, Qin Y, Liu L, Chen Q, 2020 Mitophagy and its contribution to metabolic and aging associated disorders, Liu L, Liao X, Wu H, Li Y, Zhu Y, Chen Q, 2020 Deficiency of mitophagy receptor FUNDC1 impairs mitochondrial quality and aggravates dietary-induced obesity and metabolic syndrome, Wu H, Wang Y, Li W, Chen H, Du L, Liu D, Wang X, Xu T, Liu L, Chen Q, 2019 A mitochondrial FUNDC1/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity, Li Y, Xue Y, Xu X, Wang G, Liu Y, Wu H, Li W, Wang Y, Chen Z, Zhang W, Zhu Y, Ji W, Xu T, Liu L, Chen Q, 2019 STING directly activates autophagy to tune the innate immune response, Liu D, Wu H, Wang C, Li Y, Tian H, Siraj S, Sehgal SA, Wang X, Wang J, Shang Y, Jiang Z, Liu L, Chen Q, 2019 Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy, Chen M, Chen Z, Wang Y, Tan Z, Zhu C, Li Y, Han Z, Chen L, Gao R, Liu L, Chen Q, 2016 The Bcl-xL and PGAM5 axis defines hypoxia-induced receptor-mediated mitophagy, Wu H, Xue D, Chen G, Han Z, Huang L, Zhu C, Wang X, Jin H, Wang J, Zhu Y, Liu L, Chen Q, 2014 Receptor-mediated mitophagy in yeast and mammalian systems, Liu L, Sakakibara K, Chen Q, Okamoto K, 2014 Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells, Liu L, Feng D, Chen G, Chen M, Zheng Q, Song P, Ma Q, Zhu C, Wang R, Qi W, Huang L, Xue P, Li B, Wang X, Jin H, Wang J, Yang F, Liu P, Zhu Y, Sui S, Chen Q, 2012

Areas of Focus

Regulation of mitochondrial and other organelle homeostasis and disease

Publications

Defective mitochondrial ISCs biogenesis switches on IRP1 to fine tune selective mitophagy, Wu H, Wei H, Zhang D, Sehgal SA, Zhang D, Wang X, Qin Y, Liu L, Chen Q, 2020
Mitophagy and its contribution to metabolic and aging associated disorders, Liu L, Liao X, Wu H, Li Y, Zhu Y, Chen Q, 2020
Deficiency of mitophagy receptor FUNDC1 impairs mitochondrial quality and aggravates dietary-induced obesity and metabolic syndrome, Wu H, Wang Y, Li W, Chen H, Du L, Liu D, Wang X, Xu T, Liu L, Chen Q, 2019
A mitochondrial FUNDC1/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity, Li Y, Xue Y, Xu X, Wang G, Liu Y, Wu H, Li W, Wang Y, Chen Z, Zhang W, Zhu Y, Ji W, Xu T, Liu L, Chen Q, 2019
STING directly activates autophagy to tune the innate immune response, Liu D, Wu H, Wang C, Li Y, Tian H, Siraj S, Sehgal SA, Wang X, Wang J, Shang Y, Jiang Z, Liu L, Chen Q, 2019
Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy, Chen M, Chen Z, Wang Y, Tan Z, Zhu C, Li Y, Han Z, Chen L, Gao R, Liu L, Chen Q, 2016
The Bcl-xL and PGAM5 axis defines hypoxia-induced receptor-mediated mitophagy, Wu H, Xue D, Chen G, Han Z, Huang L, Zhu C, Wang X, Jin H, Wang J, Zhu Y, Liu L, Chen Q, 2014
Receptor-mediated mitophagy in yeast and mammalian systems, Liu L, Sakakibara K, Chen Q, Okamoto K, 2014
Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells, Liu L, Feng D, Chen G, Chen M, Zheng Q, Song P, Ma Q, Zhu C, Wang R, Qi W, Huang L, Xue P, Li B, Wang X, Jin H, Wang J, Yang F, Liu P, Zhu Y, Sui S, Chen Q, 2012

Mitophagy Fundc1 Organelle Homeostasis Disease Molecular Mechanism Physiology Pathology Mitochondria Quality Control

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