Professor | Pan Pan | Asia Growth Partners

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Name	Pan Pan
Contact Information	panpan@gzhmu.edu.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Pan Pan

Contact Information

panpan@gzhmu.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Guangzhou Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	Doctorate: PhD Published over 30 academic papers H-index of 18 Over 4000 citations 5 national invention patents Led 10 research projects

University/Lab Affiliation and Title

Guangzhou Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

Doctorate: PhD
Published over 30 academic papers
H-index of 18
Over 4000 citations
5 national invention patents
Led 10 research projects

Areas of Focus	Molecular mechanisms of virus-induced inflammation Screening of antiviral drug targets Clinical translational research of stem and immune cells
Publications	Inhibition of SARS-CoV-2 replication by a ssDNA aptamer targeting the nucleocapsid protein, Huang, Y., Huang, C., Chen, J., Chen, S., Li, B., Li, J., Jin, Z., Zhang, Q., Pan, P., Du, W., Liu, L., & Liu, Z., 2024 The Interaction between SARS-CoV-2 Nucleocapsid Protein and UBC9 Inhibits MAVS Ubiquitination by Enhancing Its SUMOylation, Huang, C., Yin, Y., Pan, P., Huang, Y., Chen, S., Chen, J., Wang, J., Xu, G., Tao, X., Xiao, X., Li, J., Yang, J., Jin, Z., Li, B., Tong, Z., Du, W., Liu, L., & Liu, Z., 2023 A programmable DNA nanodevice for colorimetric detection of DNA methyltransferase activity using functionalized hemin/G-quadruplex DNAzyme, Yuan W, Xiao K, Liu X, Lai Y, Luo F, Xiao W, Wu J, Pan P, Li Y, Xiao H., 2023 SARS-CoV-2 N protein enhances the anti-apoptotic activity of MCL-1 to promote viral replication, Pan, P., Ge, W., Lei, Z., Luo, W., Liu, Y., Guan, Z., Chen, L., Yu, Z., Shen, M., Hu, D., Xiang, Q., Wang, W., Wan, P., Tian, M., Yu, Y., Luo, Z., Chen, X., Xiao, H., Zhang, Q., Liang, X., Chen, X., Li, Y., & Wu, J., 2023 Inhibitory effects of Patchouli alcohol on the early lifecycle stages of influenza A virus, Fan, Y., Zhang, Q., Zhang, W., Lai, Y., Long, H., Huang, H., Zhan, S., Liu, X., Lai, J., Zhang, Z., Pan, P., Su, Z., & Li, G., 2023 A vaccine delivery system promotes strong immune responses against SARS-CoV-2 variants, Lei, Z., Zhu, L., Pan, P., Ruan, Z., Gu, Y., Xia, X., Wang, S., Ge, W., Yao, Y., Luo, F., Xiao, H., Guo, J., Ding, Q., Yin, Z., Li, Y., Luo, Z., Zhang, Q., Chen, X., & Wu, J., 2023 Editorial: The role of inflammasome in viral infection, Wan, P., Zhang, Y., Pan, P., & Li, Y., 2023 In Memory of the Virologist Jianguo Wu, 1957-2022, Yang, G., Yue, Z., Pan, P., & Li, Y., 2023 SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation, Pan, P., Shen, M., Yu, Z., Ge, W., Chen, K., Tian, M., Xiao, F., Wang, Z., Wang, J., Jia, Y., Wang, W., Wan, P., Zhang, J., Chen, W., Lei, Z., Chen, X., Luo, Z., Zhang, Q., Xu, M., Li, G., Li, Y., & Wu, J., 2021 Sericin and sericin-derived peptide alleviate viral pathogenesis in mice though inhibiting lactate production and facilitating antiviral response, Li Y, Huang Y, Pan P, Che X, Zhang Y, Zhang Y, Amal A, Li X, Niu W, Luo N, Zhang W, Gao D, Tan Q, Zhang Q, Xing X, Luo Z, Wu J., 2021 DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junction, Pan, P., Li, G., Shen, M., Yu, Z., Ge, W., Lao, Z., Fan, Y., Chen, K., Ding, Z., Wang, W., Wan, P., Shereen, M. A., Luo, Z., Chen, X., Zhang, Q., Lin, L., & Wu, J., 2021 Cinnamic acid inhibits Zika virus by inhibiting RdRp activity, Chen, Y., Li, Z., Pan, P., Lao, Z., Xu, J., Li, Z., Zhan, S., Liu, X., Wu, Y., Wang, W., Li, G., 2021 Dengue Virus M Protein Promotes NLRP3 Inflammasome Activation To Induce Vascular Leakage in Mice, Pan, P., Zhang, Q., Liu, W., Wang, W., Lao, Z., Zhang, W., Shen, M., Wan, P., Xiao, F., Liu, F., Zhang, W., Tan, Q., Liu, X., Wu, K., Liu, Y., Li, G., & Wu, J., 2019 Dengue Virus Infection Activates Interleukin-1β to Induce Tissue Injury and Vascular Leakage, Pan, P., Zhang, Q., Liu, W., Wang, W., Yu, Z., Lao, Z., Zhang, W., Shen, M., Wan, P., Xiao, F., Shereen, M. A., Zhang, W., Tan, Q., Liu, Y., Liu, X., Wu, K., Liu, Y., Li, G., & Wu, J., 2019 Molecular epidemiology demonstrates that imported and local strains circulated during the 2014 dengue outbreak in Guangzhou, China, Li, G., Pan, P., He, Q., Kong, X., Wu, K., Zhang, W., Liu, Y., Huang, H., Liu, J., Zhang, Z., Wu, D., Lai, X., Liu, X., & Wu, J., 2017

Areas of Focus

Molecular mechanisms of virus-induced inflammation
Screening of antiviral drug targets
Clinical translational research of stem and immune cells

Publications

Inhibition of SARS-CoV-2 replication by a ssDNA aptamer targeting the nucleocapsid protein, Huang, Y., Huang, C., Chen, J., Chen, S., Li, B., Li, J., Jin, Z., Zhang, Q., Pan, P., Du, W., Liu, L., & Liu, Z., 2024
The Interaction between SARS-CoV-2 Nucleocapsid Protein and UBC9 Inhibits MAVS Ubiquitination by Enhancing Its SUMOylation, Huang, C., Yin, Y., Pan, P., Huang, Y., Chen, S., Chen, J., Wang, J., Xu, G., Tao, X., Xiao, X., Li, J., Yang, J., Jin, Z., Li, B., Tong, Z., Du, W., Liu, L., & Liu, Z., 2023
A programmable DNA nanodevice for colorimetric detection of DNA methyltransferase activity using functionalized hemin/G-quadruplex DNAzyme, Yuan W, Xiao K, Liu X, Lai Y, Luo F, Xiao W, Wu J, Pan P, Li Y, Xiao H., 2023
SARS-CoV-2 N protein enhances the anti-apoptotic activity of MCL-1 to promote viral replication, Pan, P., Ge, W., Lei, Z., Luo, W., Liu, Y., Guan, Z., Chen, L., Yu, Z., Shen, M., Hu, D., Xiang, Q., Wang, W., Wan, P., Tian, M., Yu, Y., Luo, Z., Chen, X., Xiao, H., Zhang, Q., Liang, X., Chen, X., Li, Y., & Wu, J., 2023
Inhibitory effects of Patchouli alcohol on the early lifecycle stages of influenza A virus, Fan, Y., Zhang, Q., Zhang, W., Lai, Y., Long, H., Huang, H., Zhan, S., Liu, X., Lai, J., Zhang, Z., Pan, P., Su, Z., & Li, G., 2023
A vaccine delivery system promotes strong immune responses against SARS-CoV-2 variants, Lei, Z., Zhu, L., Pan, P., Ruan, Z., Gu, Y., Xia, X., Wang, S., Ge, W., Yao, Y., Luo, F., Xiao, H., Guo, J., Ding, Q., Yin, Z., Li, Y., Luo, Z., Zhang, Q., Chen, X., & Wu, J., 2023
Editorial: The role of inflammasome in viral infection, Wan, P., Zhang, Y., Pan, P., & Li, Y., 2023
In Memory of the Virologist Jianguo Wu, 1957-2022, Yang, G., Yue, Z., Pan, P., & Li, Y., 2023
SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation, Pan, P., Shen, M., Yu, Z., Ge, W., Chen, K., Tian, M., Xiao, F., Wang, Z., Wang, J., Jia, Y., Wang, W., Wan, P., Zhang, J., Chen, W., Lei, Z., Chen, X., Luo, Z., Zhang, Q., Xu, M., Li, G., Li, Y., & Wu, J., 2021
Sericin and sericin-derived peptide alleviate viral pathogenesis in mice though inhibiting lactate production and facilitating antiviral response, Li Y, Huang Y, Pan P, Che X, Zhang Y, Zhang Y, Amal A, Li X, Niu W, Luo N, Zhang W, Gao D, Tan Q, Zhang Q, Xing X, Luo Z, Wu J., 2021
DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junction, Pan, P., Li, G., Shen, M., Yu, Z., Ge, W., Lao, Z., Fan, Y., Chen, K., Ding, Z., Wang, W., Wan, P., Shereen, M. A., Luo, Z., Chen, X., Zhang, Q., Lin, L., & Wu, J., 2021
Cinnamic acid inhibits Zika virus by inhibiting RdRp activity, Chen, Y., Li, Z., Pan, P., Lao, Z., Xu, J., Li, Z., Zhan, S., Liu, X., Wu, Y., Wang, W., Li, G., 2021
Dengue Virus M Protein Promotes NLRP3 Inflammasome Activation To Induce Vascular Leakage in Mice, Pan, P., Zhang, Q., Liu, W., Wang, W., Lao, Z., Zhang, W., Shen, M., Wan, P., Xiao, F., Liu, F., Zhang, W., Tan, Q., Liu, X., Wu, K., Liu, Y., Li, G., & Wu, J., 2019
Dengue Virus Infection Activates Interleukin-1β to Induce Tissue Injury and Vascular Leakage, Pan, P., Zhang, Q., Liu, W., Wang, W., Yu, Z., Lao, Z., Zhang, W., Shen, M., Wan, P., Xiao, F., Shereen, M. A., Zhang, W., Tan, Q., Liu, Y., Liu, X., Wu, K., Liu, Y., Li, G., & Wu, J., 2019
Molecular epidemiology demonstrates that imported and local strains circulated during the 2014 dengue outbreak in Guangzhou, China, Li, G., Pan, P., He, Q., Kong, X., Wu, K., Zhang, W., Liu, Y., Huang, H., Liu, J., Zhang, Z., Wu, D., Lai, X., Liu, X., & Wu, J., 2017

Virus Inflammation Molecular Mechanism Antiviral Drug Target Stem Cells Immune Cells Clinical

Yihong Peng - Peking University

Ling Wang - Peking University

Dan Lu - Peking University

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