Upload Avatar (500 x 500)
Guoshuai Feng
Basic Medical Sciences
Guangzhou Medical University
Guangdong
Language: Chinese, English
Immunology
Heart Disease
Myocardial Infarction
Myocarditis
Bone Marrow Cells
Monocytes
Macrophages
Neutrophils
Gene Changes
Immunotherapy
Areas of Focus
- Immunological mechanisms and therapeutic strategies for heart diseases
Work Experience
- 2017-2022 - Washington University School of Medicine in St. Louis - Postdoctoral Researcher
Academic Background & Achievements
- PhD: Sun Yat-sen University
Publications
- CCL17 aggravates myocardial injury by suppressing recruitment of regulatory T cells, Guoshuai Feng, et.al and Kory Lavine, 2022
- CCL17 protects against EMCV induced myocarditis by suppressing recruitment of regulatory T cells, Guoshuai Feng, et.al and Kory Lavine, 2023
- Synthesis of the novel PARP-1 inhibitor AG-690/11026014 and its protective effects on angiotensin II-induced mouse cardiac remodeling, Feng, Guo-shuai, et.al and Liu, Pei-qing, 2017
- Ferroptotic cell death and TLR4/Trif signaling initiate neutrophil recruitment after heart transplantation, Wenjun Li, Guoshuai Feng, et.al, Kory J. Lavine and Daniel Kreisel, 2019
- CCR2-targeted PET imaging of injured heart, Gyu Seong Heo, Benjamin Kopecky, Deborah Sultan, Guoshuai Feng, et.al, Yongjian Liu, 2019
- Molecular Imaging Visualizes Recruitment of Inflammatory Monocytes and Macrophages to the Injured Heart, Gyu Seong Heo, Benjamin Kopecky, Deborah Sultan, Monica Ou, Guoshuai Feng, et.al, Yongjian Liu and Kory Lavine, 2019
- Resident cardiac macrophages mediate adaptive myocardial remodeling, Nicole R. Wong, Jay Mohan, Benjamin J. Kopecky, Shuchi Guo, Lixia Du, Jamison Leid, Guoshuai Feng, et.al, and Kory Lavine, 2021
- SIRT3 prevents angiotensin II-induced renal tubular epithelial-mesenchymal transition by ameliorating oxidative stress and mitochondrial dysfunction, Ping He, Zhuoming Li, Zhongbao Yue, Hui Gao, Guoshuai Feng, et.al, and Peiqing Liu, 2018
- Protective effect of chinonin in MPTP-induced C57BL/6 mouse model of Parkinson's disease, Guoshuai Feng, et al. and Jie Jiang, 2014
- C33(S), a novel PDE9A inhibitor, protects against rat cardiac hypertrophy through upregulating cGMP signaling, Pan-xia Wang, Zhuo-ming Li, Si-dong Cai, Jing-yan Li, Ping He, Yi Huang, Guo-shuai Feng, et.al, and Peiqing Liu, 2017
Awards
- 2023: Selected for the 'Nanshan Scholar (Key Talent)' program at Guangzhou Medical University
