Professor | Yu Xia Zhang | Asia Growth Partners

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Name	Yu Xia Zhang
Language ability	Chinese, English
Province	Guangdong

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Name

Yu Xia Zhang

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Guangzhou Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2007 - PhD: University of Chinese Academy of Sciences Achievement: Conducted research on the pathogenesis of pediatric autoimmune diseases at the University of Cambridge and Walter & Eliza Hall Institute of Medical Research Achievement: Received 4 national project grants from JDRF and NHMRC Achievement: Authorized 2 invention patents Achievement: Co-supervised 2 doctoral students
Work Experience	2007-2009 - University of Cambridge - Research on pediatric autoimmune diseases 2009-2016 - Walter & Eliza Hall Institute of Medical Research - Research on pediatric autoimmune diseases 2016-present - Return to China - Pearl River Scholar Distinguished Professor, Guangdong Province
Awards	2016: Pearl River Scholar Distinguished Professor, Guangdong Province 2019: Recognized as one of the 'Top 10 Medical Advances in China'

University/Lab Affiliation and Title

Guangzhou Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2007 - PhD: University of Chinese Academy of Sciences
Achievement: Conducted research on the pathogenesis of pediatric autoimmune diseases at the University of Cambridge and Walter & Eliza Hall Institute of Medical Research
Achievement: Received 4 national project grants from JDRF and NHMRC
Achievement: Authorized 2 invention patents
Achievement: Co-supervised 2 doctoral students

Work Experience

2007-2009 - University of Cambridge - Research on pediatric autoimmune diseases
2009-2016 - Walter & Eliza Hall Institute of Medical Research - Research on pediatric autoimmune diseases
2016-present - Return to China - Pearl River Scholar Distinguished Professor, Guangdong Province

Awards

2016: Pearl River Scholar Distinguished Professor, Guangdong Province
2019: Recognized as one of the 'Top 10 Medical Advances in China'

Areas of Focus	Regional immune pathogenesis of chronic diseases in children Infection immunity Immunodeficiency and autoinflammation
Publications	Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia, Jun Wang, et al., 2020 IL-17 production by tissue-resident MAIT cells is locally induced in children with pneumonia, Lu, B., et al., 2020 Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways, Huang, B., et al., 2019 Cord Blood CD8+ T Cells Have a Natural Propensity to Express IL-4 in a Fatty Acid Metabolism and Caspase Activation-Dependent Manner, Zhang, Y., et al., 2018 CD52 inhibits Toll-like receptor activation of NF-kappaB and triggers apoptosis to suppress inflammation, Rashidi, M., et al., 2018 Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)-LRR oligomerization interface, Moghaddas, F., et al., 2018 The Development and Diversity of ILCs, NK Cells and Their Relevance in Health and Diseases, Zhang, Y. and B. Huang, 2017 Life and Death of Activated T Cells: How Are They Different from Naive T Cells?, Zhan, Y., et al., 2017 MicroRNAs in CD4(+) T cell subsets are markers of disease risk and T cell dysfunction in individuals at risk for type 1 diabetes, Zhang, Y., et al., 2016 Cord blood monocyte-derived inflammatory cytokines suppress IL-2 and induce nonclassic 'T(H)2-type' immunity associated with development of food allergy, Zhang, Y., et al., 2016 Genome-wide DNA methylation analysis identifies hypomethylated genes regulated by FOXP3 in human regulatory T cells, Zhang, Y., et al., 2013 T cell regulation mediated by interaction of soluble CD52 with the inhibitory receptor Siglec-10, Bandala-Sanchez, E., et al., 2013 The polycomb repressive complex 2 governs life and death of peripheral T cells, Zhang, Y., et al., 2014

Areas of Focus

Regional immune pathogenesis of chronic diseases in children
Infection immunity
Immunodeficiency and autoinflammation

Publications

Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia, Jun Wang, et al., 2020
IL-17 production by tissue-resident MAIT cells is locally induced in children with pneumonia, Lu, B., et al., 2020
Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways, Huang, B., et al., 2019
Cord Blood CD8+ T Cells Have a Natural Propensity to Express IL-4 in a Fatty Acid Metabolism and Caspase Activation-Dependent Manner, Zhang, Y., et al., 2018
CD52 inhibits Toll-like receptor activation of NF-kappaB and triggers apoptosis to suppress inflammation, Rashidi, M., et al., 2018
Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)-LRR oligomerization interface, Moghaddas, F., et al., 2018
The Development and Diversity of ILCs, NK Cells and Their Relevance in Health and Diseases, Zhang, Y. and B. Huang, 2017
Life and Death of Activated T Cells: How Are They Different from Naive T Cells?, Zhan, Y., et al., 2017
MicroRNAs in CD4(+) T cell subsets are markers of disease risk and T cell dysfunction in individuals at risk for type 1 diabetes, Zhang, Y., et al., 2016
Cord blood monocyte-derived inflammatory cytokines suppress IL-2 and induce nonclassic 'T(H)2-type' immunity associated with development of food allergy, Zhang, Y., et al., 2016
Genome-wide DNA methylation analysis identifies hypomethylated genes regulated by FOXP3 in human regulatory T cells, Zhang, Y., et al., 2013
T cell regulation mediated by interaction of soluble CD52 with the inhibitory receptor Siglec-10, Bandala-Sanchez, E., et al., 2013
The polycomb repressive complex 2 governs life and death of peripheral T cells, Zhang, Y., et al., 2014

Chronic Diseases Children Immune Pathogenesis Regional Infection Immunity Immunodeficiency Autoinflammation Research Pediatrics

Jun Wang - Guangzhou Medical University

Ma Ling - China Medical University

Ying Sun - Capital Medical University

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