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Wei Xu
Basic Medical Sciences
Guangzhou Medical University
Beijing
Language: Chinese, English
Contact
Ebola Virus H7N9 Influenza Virus Dengue Virus Zika Virus Immune Evasion Pathogenesis Molecular Mechanisms Structural Biology Vp24 Vp30
Areas of Focus
  • Molecular mechanisms of immune evasion and pathogenesis of highly pathogenic viruses
Work Experience
  • 2010-2017 - Indiana University School of Medicine and Washington University School of Medicine in St. Louis - Research work
Academic Background & Achievements
  • 2009 - PhD: University of Chinese Academy of Sciences
  • Published 10 SCI research papers with a cumulative impact factor of 60
Publications
  • Human IFIT3 modulates IFIT1 RNA binding specificity and protein stability., Britney Johnson, Laura A. VanBlargan, Wei Xu, James P. White, Chao Shan, Pei-Yong Shi, Rong Zhang, Jagat Adhikari, Michael L.Gross, Daisy W. Leung, Michael S. Diamond, Gaya K. Amarasinghe, 2018
  • Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis., Wei Xu, Priya Luthra, Chao Wu, Jyoti Batra, Daisy W. Leung, Christopher F. Basler, Gaya K. Amarasinghe, 2017
  • Ebola virus VP24 targets a unique NLS-binding site on karyopherin alpha5 to selectively compete with nuclear import of phosphorylated STAT1., Wei Xu, Megan R. Edwards, Dominika M. Borek, Alicia R. Feagins, Anuradha Mittal, Joshua B. Alinger, Kayla N. Berry, Benjamin Yen, Jennifer Hamilton, Rohit V.Pappu, Tom J. Brett, Daisy W. Leung, Christopher F. Basler, Gaya K. Amarasinghe, 2014
  • In silico derived small molecules bind the filovirus VP35 protein and inhibit its polymerase co-factor activity., Craig S Brown, Michael S Lee, Daisy W Leung, Tianjiao Wang, Wei Xu, Priya Luthra, Manu Anantpadma, Reed S Shabman, Lisa M Melito, Karen S Macmillan, Dominika M Borek, Zbyszek Otwinowski, Parameshwaran Ramanan, Alisha J Stubbs, Dayna S Peterson, Jennifer M Binning, Marco Tonelli, Mark A Olson, Rob Davey, Joseph M Ready, Christopher F Basler, Gaya K Amarasinghe, 2014
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