Professor | Xiaoming Wang | Asia Growth Partners

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Name	Xiaoming Wang
Contact Information	xmwang@njmu.edu.cn
Language ability	English, Chinese
Province	Jiangsu

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Name

Xiaoming Wang

Contact Information

xmwang@njmu.edu.cn

Language ability

English, Chinese

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1998-2003 Bachelor: Shandong University 2003-2009 Doctorate: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences Discovered a new mechanism regulating T lymphocyte antigen receptor diversification, published as first author in Nat Immunol (2008) Postdoctoral research at University of California, San Francisco, discovered regulatory mechanisms of B cell immune response, published as first author in J Exp Med (2011, 2014)
Work Experience	2009-2014 - University of California, San Francisco - Postdoctoral Researcher 2014-present - Nanjing Medical University - Professor

University/Lab Affiliation and Title

Nanjing Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1998-2003 Bachelor: Shandong University
2003-2009 Doctorate: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
Discovered a new mechanism regulating T lymphocyte antigen receptor diversification, published as first author in Nat Immunol (2008)
Postdoctoral research at University of California, San Francisco, discovered regulatory mechanisms of B cell immune response, published as first author in J Exp Med (2011, 2014)

Work Experience

2009-2014 - University of California, San Francisco - Postdoctoral Researcher
2014-present - Nanjing Medical University - Professor

Areas of Focus	Immune response and major diseases
Publications	Jmjd1c demethylates STAT3 to restrain plasma cell differentiation and rheumatoid arthritis., Yin Y, Yang X, Wu S, Ding X, Zhu H, Long X, Wang Y, Zhai S, Chen Y, Che N, Chen J, Wang X, 2022 Histone methyltransferase Nsd2 ensures maternal-fetal immune tolerance by promoting regulatory T-cell recruitment., Zhang L, Long X, Yin Y, Wang J, Zhu H, Chen J, Wang Y, Chen Y, Wang X, 2022 The epigenetic regulation of the germinal center response., Wu S, Yin Y, Wang X, 2022 SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways., Yuan H, Han Y, Wang X, Li N, Liu Q, Yin Y, Wang H, Pan L, Li L, Song K, Qiu T, Pan Q, Chen Q, Zhang G, Zang Y, Tan M, Zhang J, Li Q, Wang X, Jiang J, Qin J, 2020 Histone methyltransferase Nsd2 is required for follicular helper T cell differentiation., Long X, Zhang L, Zhang Y, Min M, Lin B, Chen J, Ma X, Zhai S, Cai Z, Liu Y, Lu Y, Che N, Tan W, Qin J, Wang X, 2020 Pathogenic CARD11 mutations affect B-cell development and differentiation through a non-canonical pathway., Wei Z, Zhang Y, Chen J, Hu Y, Jia P, Wang X, Zhao Q, Deng Y, Li N, Zang Y, Qin J, Wang X, Lu W, 2019 Methyltransferase Nsd2 Ensures Germinal Center Selection by Promoting Adhesive Interactions between B Cells and Follicular Dendritic Cells., Chen J, Li N, Yin Y, Zheng N, Min M, Lin B, Zhang L, Long X, Zhang Y, Cai Z, Zhai S, Qin J, Wang X, 2018 Uhrf1 regulates germinal center B cell expansion and affinity maturation to control viral infection., Chen C, Zhai S, Zhang L, Chen J, Long X, Qin J, Li J, Huo R, Wang X, 2018 Lis1 regulates germinal center B cell antigen acquisition and affinity maturation., Chen J, Cai Z, Zhang L, Yin Y, Chen X, Chen C, Zhang Y, Zhai S, Long X, Liu X, Wang X, 2017 Gpr18 is required for a normal CD8aa intestine intraepithelial lymphocyte compartment., Wang X, Sumida H, Cyster JG, 2014 Follicular dendritic cells help establish follicle identity and promote B cell retention in germinal centers., Wang X, Cho B, Suzuki K, Xu Y, Green JA, An J, Cyster JG, 2011 c-fos enhances the survival of thymocytes during positive selection by upregulating bcl-2., Wang X, Zhang Y, Xiao G, Gao X, Liu X, 2009 Regulation of Tcrb recombination ordering by c-fos-dependent RAG deposition., Wang X, Xiao G, Zhang Y, Wen X, Gao X, Okada S, Liu X, 2008

Areas of Focus

Immune response and major diseases

Publications

Jmjd1c demethylates STAT3 to restrain plasma cell differentiation and rheumatoid arthritis., Yin Y, Yang X, Wu S, Ding X, Zhu H, Long X, Wang Y, Zhai S, Chen Y, Che N, Chen J, Wang X, 2022
Histone methyltransferase Nsd2 ensures maternal-fetal immune tolerance by promoting regulatory T-cell recruitment., Zhang L, Long X, Yin Y, Wang J, Zhu H, Chen J, Wang Y, Chen Y, Wang X, 2022
The epigenetic regulation of the germinal center response., Wu S, Yin Y, Wang X, 2022
SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways., Yuan H, Han Y, Wang X, Li N, Liu Q, Yin Y, Wang H, Pan L, Li L, Song K, Qiu T, Pan Q, Chen Q, Zhang G, Zang Y, Tan M, Zhang J, Li Q, Wang X, Jiang J, Qin J, 2020
Histone methyltransferase Nsd2 is required for follicular helper T cell differentiation., Long X, Zhang L, Zhang Y, Min M, Lin B, Chen J, Ma X, Zhai S, Cai Z, Liu Y, Lu Y, Che N, Tan W, Qin J, Wang X, 2020
Pathogenic CARD11 mutations affect B-cell development and differentiation through a non-canonical pathway., Wei Z, Zhang Y, Chen J, Hu Y, Jia P, Wang X, Zhao Q, Deng Y, Li N, Zang Y, Qin J, Wang X, Lu W, 2019
Methyltransferase Nsd2 Ensures Germinal Center Selection by Promoting Adhesive Interactions between B Cells and Follicular Dendritic Cells., Chen J, Li N, Yin Y, Zheng N, Min M, Lin B, Zhang L, Long X, Zhang Y, Cai Z, Zhai S, Qin J, Wang X, 2018
Uhrf1 regulates germinal center B cell expansion and affinity maturation to control viral infection., Chen C, Zhai S, Zhang L, Chen J, Long X, Qin J, Li J, Huo R, Wang X, 2018
Lis1 regulates germinal center B cell antigen acquisition and affinity maturation., Chen J, Cai Z, Zhang L, Yin Y, Chen X, Chen C, Zhang Y, Zhai S, Long X, Liu X, Wang X, 2017
Gpr18 is required for a normal CD8aa intestine intraepithelial lymphocyte compartment., Wang X, Sumida H, Cyster JG, 2014
Follicular dendritic cells help establish follicle identity and promote B cell retention in germinal centers., Wang X, Cho B, Suzuki K, Xu Y, Green JA, An J, Cyster JG, 2011
c-fos enhances the survival of thymocytes during positive selection by upregulating bcl-2., Wang X, Zhang Y, Xiao G, Gao X, Liu X, 2009
Regulation of Tcrb recombination ordering by c-fos-dependent RAG deposition., Wang X, Xiao G, Zhang Y, Wen X, Gao X, Okada S, Liu X, 2008

Immune Response Major Diseases Lymphocyte Development Differentiation Mechanism Regulation Epigenetic Regulation B Cell T Cell Lymphoma Molecular Mechanisms

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