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Xiu-Lan Sun
xiulans@njmu.edu.cn
Chinese, English
Jiangsu
Nanjing Medical University
Basic Medical Sciences
  • 1991-1996 Bachelor: Clinical Medicine, Yangzhou University
  • 1996-1999 Master: Physiology, Nanjing Medical University
  • 2001-2004 Doctorate: Pharmacology, Nanjing Medical University
  • Achievements: Over 30 SCI-indexed papers, 8 patents, multiple awards including Beijing Science and Technology Award
  • 1999-2001 Lecturer: Department of Physiology, Nanjing Medical University
  • 2004-present Lecturer, Associate Professor, Professor: Department of Pharmacology, Nanjing Medical University
  • Jiangsu Women's Achievement Model
  • Jiangsu Advanced Individual in Education
  • Nanjing Medical University 'Three Educations' Model
  • Nanjing Medical University Outstanding Young and Middle-aged Academic Leader
  • Instructor of National College Students Basic Medicine Innovation Forum Third Prize
  • Jiangsu '333 Project' Third Level Training Object
  • Jiangsu 'Six Talent Peaks' (A Class) High-level Talent Training Object
  • Chinese Pharmacological Society Young Pharmacologist Award
  • Beijing Science and Technology Progress First Prize
  • Military Science and Technology Progress First Prize
  • Nanjing Science and Technology Progress Third Prize
Pathological damage mechanisms and neuroprotective targets in neuropsychiatric diseases
  • FTY720 exerts anti-glioma effects by regulating the glioma microenvironment through increased CXCR4 internalization by glioma-associated microglia., Xu-Dong Guo, Juan Ji, Teng-Fei Xue, Yu-Qin Sun, Ruo-Bing Guo, Hong Cheng, Xiu-Lan Sun, 2020
  • LncRNA RMST-mediated miR-107 transcription promotes OGD-induced neuronal apoptosis via interacting with hnRNPK., Hong Cheng, Mei Sun, Zhao-Lu Wang, Qian Wu, Juan Yao, Guang Ren, Xiu-Lan Sun, 2020
  • MicroRNA-99a is a Potential Target for Regulating Hypothalamic Synaptic Plasticity in the Peri/Postmenopausal Depression Model., Jin Yang, Ling Zhang, Lu-Lu Cao, Jun Qi, Ping Li, Xi-Peng Wang, Xiu-Lan Sun, 2019
  • The intra-nuclear SphK2-S1P axis facilitates M1-to-M2 shift of microglia via suppressing HDAC1-mediated KLF4 deacetylation., Juan Ji, Juan Wang, Jin Yang, Xi-Peng Wang, Jing-Jing Huang, Teng-Fei Xue, Xiu-Lan Sun, 2019
  • Quercetin Inhibits the Proliferation of Glycolysis-Addicted HCC Cells by Reducing Hexokinase 2 and Akt-mTOR Pathway., Hongyan Wu, Lanlan Pan, Cuixiang Gao, Hongtao Xu, Yanping Li, Lihu Zhang, Linwei Ma, Li Meng, Xiulan Sun, Hongbing Qin, 2019
  • LncRNA RMST activates TAK1-mediated NF-κB signaling and promotes activation of microglial cells via competitively binding with hnRNPK., Xiu-Lan Sun, Zhao-Lu Wang, Qian Wu, Shan-Quan Jin, Juan Yao, Hong Cheng, 2019
  • Establishment and evaluation of a novel mouse model of peri/postmenopausal depression., Ling Zhang, Lu-Lu Cao, Dan-Dan Yang, Jian-Hua Ding, Xu-Dong Guo, Teng-Fei Xue, Xiao-Jie Zhao, Xiu-Lan Sun, 2019
  • Antagonizing PPARγ facilitates M1-to-M2 shift of microglia by enhancing autophagy via the LKB1-AMPK signaling pathway., Juan Ji, Teng-Fei Xue, Xu-Dong Guo, Jin Yang, Ruo-Bing Guo, Juan Wang, Ji-Ye Huang, Xiao-Jie Zhao, Xiu-Lan Sun, 2018
  • S1PR3 is essential for phosphorylated fingolimod to protect astrocytes against OGD-induced neuroinflammation via inhibiting TLR2/4-NFκB signaling., Yin-Feng Dong, Ruo-Bing Guo, Juan Ji, Lu-Lu Cao, Ling Zhang, Zheng-Zhen Chen, Ji-Ye Huang, Jin Wu, Jun Lu, Xiu-Lan Sun, 2018
  • Activation of ATP-sensitive potassium channel by iptakalim normalizes stress-induced HPA axis disorder and depressive behaviour by alleviating inflammation and oxidative stress in mouse hypothalamus., Zhao XJ, Zhao Z, Yang DD, Cao LL, Zhang L, Ji J, Gu J, Huang JY, Sun XL, 2017
  • Rosiglitazone exerts an anti-depressive effect in unpredictable chronic mild-stress-induced depressive mice by maintaining essential neuron autophagy and inhibiting excessive astrocytic apoptosis., Zhan Zhao, Ling Zhang, Xu-Dong Guo, Lu-Lu Cao, Teng-Fei Xue, Xiao-Jie Zhao, Dan-Dan Yang, Jin Yang, Juan Ji, Ji-Ye Huang, Xiu-Lan Sun, 2017
  • PD149163 induces hypothermia to protect against brain injury in acute cerebral ischemic rats., Teng-Fei Xue, Xu Ding, Juan Ji, Hui Yan, Ji-Ye Huang, Xu-Dong Guo, Jin Yang, Xiu-Lan Sun, 2017
  • PPARβ/δ activation protects against corticosterone-induced ER stress in astrocytes by inhibiting the CpG hypermethylation of MicroRNA-181a., Ji J, Zeng XN, Cao LL, Zhang L, Zhao Z, Yang DD, Xiu-Lan Sun, 2017
  • Potential role of microRNA-7 in the anti-neuroinflammation effects of nicorandil in astrocytes induced by oxygen-glucose deprivation., Yin-Feng Dong, Zheng-Zhen Chen, Zhan Zhao, Dan-Dan Yang, Juan Ji, Xiu-Lan Sun, 2016
  • Memantine mediates neuroprotection via regulating neurovascular unit in a mouse model of focal cerebral ischemia., Chen ZZ, Yang DD, Zhao Z, Yan H, Ji J, Sun XL, 2016
  • Iptakalim protects against ischemic injury by improving neurovascular unit function in the mouse brain., Ji J, Yan H, Chen ZZ, Zhao Z, Yang DD, Sun XL, Shi YP, 2015
  • Lentinan exerts synergistic apoptotic effects with paclitaxel in A549 cells via activating ROS-TXNIP-NLRP3 inflammasome., Wei Liu, Jun Gu, Jun Qi, Xiao-Ning Zeng, Juan Ji, Zheng-Zhen Chen, Xiu-Lan Sun, 2015
  • Inhaled budesonide protects against chronic asthma-induced neuroinflammation in mouse brain., Xia MX, Ding X, Qi J, Gu J, Hu G, Sun XL, 2014
  • Uncoupling protein 2 deficiency aggravates astrocytic endoplasmic reticulum stress and nod-like receptor protein 3 inflammasome activation., Lu M, Sun XL, Qiao C, Liu Y, Ding JH, Hu G, 2014
  • Nicorandil inhibits inflammasome activation and Toll-like receptor signal transduction to protect against oxygen-glucose deprivation induced inflammation in BV-2 cells., Zhao AP, Dong YF, Liu W, Gu J, Sun XL, 2014
Neuropsychiatric Diseases Pathological Mechanisms Neuroprotection Brain Stroke Depression Microglia Trem2 Neuroinflammation Neurovascular Unit Pharmacology

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