Professor | Zhong Li | Asia Growth Partners

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Name	Zhong Li
Contact Information	lizhong@njmu.edu.cn
Language ability	English, Chinese
Province	Jiangsu

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Name

Zhong Li

Contact Information

lizhong@njmu.edu.cn

Language ability

English, Chinese

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2003-2007 PhD: Hong Kong University of Science and Technology Achievement: Jiangsu Province Distinguished Professor Achievement: Leader of Jiangsu Province Innovation Team
Work Experience	2007-2008 - Hong Kong University of Science and Technology - Assistant Researcher 2008-2012 - University of Texas Southwestern Medical Center - Postdoctoral Researcher 2013-present - Nanjing Medical University - Professor
Awards	2016: Jiangsu Province Distinguished Professor 2017: Leader of Jiangsu Province Innovation Team

University/Lab Affiliation and Title

Nanjing Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2003-2007 PhD: Hong Kong University of Science and Technology
Achievement: Jiangsu Province Distinguished Professor
Achievement: Leader of Jiangsu Province Innovation Team

Work Experience

2007-2008 - Hong Kong University of Science and Technology - Assistant Researcher
2008-2012 - University of Texas Southwestern Medical Center - Postdoctoral Researcher
2013-present - Nanjing Medical University - Professor

Awards

2016: Jiangsu Province Distinguished Professor
2017: Leader of Jiangsu Province Innovation Team

Areas of Focus	Molecular mechanisms of glucose and lipid metabolism regulation
Publications	The Patatin-Like Phospholipase Domain Containing Protein 7 Facilitates VLDL Secretion by Modulating ApoE Stability, Xiuyun Wang, Min Guo, Qian Wang, Qingjie Wang, Shasha Zuo, Xu Zhang, Hui Tong, Jizheng Chen, Huiming Wang, Xiaowei Chen, Junyuan Guo, Xiong Su, Hui Liang, Hongwen Zhou, John Zhong Li, 2020 The Metabolic Regulator Small Heterodimer Partner Contributes to the Glucose and Lipid Homeostasis Abnormalities Induced by Hepatitis C Virus Infection, Jizheng Chen, Yue Zhou, Yuan Zhuang, Tian Qin, Min Guo, Jing Jiang, Junqi Niu, John Zhong Li, Xinwen Chen, Qian Wang, 2019 Long non-coding RNA Bhmt-AS attenuates hepatic gluconeogenesis via modulation of Bhmt expression, Xuan Shen, Yajun Zhang, Xu Zhang, Yiwei Yao, Yujie Zheng, Xianwei Cui, Chang Liu, Qian Wang, John Zhong Li, 2019 New insight into inter-organ crosstalk contributing to the pathogenesis of non-alcoholic fatty liver disease (NAFLD), Xu Zhang, Xuetao Ji, Qian Wang, John Zhong Li, 2018 Differential Roles of Cell Death-inducing DNA Fragmentation Factor-α-like Effector (CIDE) Proteins in Promoting Lipid Droplet Fusion and Growth in Subpopulations of Hepatocytes, Wenyi Xu, Lizhen Wu, Miao Yu, Feng-Jung Chen, Muhammad Arshad, Xiayu Xia, Hao Ren, Jinhai Yu, Li Xu, Dijin Xu, John Zhong Li, Peng Li, and Linkang Zhou, 2016 Chronic overexpression of PNPLA3I148M in mouse liver causes hepatic steatosis, John Zhong Li, Yongcheng Huang, Ruchan Karaman, Pavlina T. Ivanova, H. Alex Brown, Thomas Roddy, Jose Castro-Perez, Jonathan C. Cohen, and Helen H. Hobbs, 2012 Pnpla3/Adiponutrin deficient in mice does not contribute to fatty liver disease or the metabolic syndrome, Mahesh K. Basantani Mitch T. Sitnick, Dani Brenner, Noah P. Gardner, John Zhong Li, Gabriele Schoiswohl, Kui Yang, Manju Kumari, Richard W Gross, Rudolf Zechner, and Erin E. Kershaw, 2011 Control of cholesterol biosynthesis, uptake and storage in hepatocytes by Cideb, John Zhong Li, Yao Lei, Yue Wang, Yinxin Zhang, Jing Ye, Xiayu Xia, Xianming Pan and Peng Li, 2010 A Feed-forward Loop Amplifies Nutritional Regulation of PNPLA3, Yongcheng Huang, Shaoqing He, John Zhong Li, Young-Kyo Seo, Timothy F. Osborne, Jonathan C. Cohen, and Helen H. Hobbs, 2010 A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis, Shaoqing He, Christopher McPhaul, John Zhong Li, Rita Garuti, Lisa Kinch, Nick V Grishin, Jonathan C. Cohen, and Helen H. Hobbs, 2010 Cideb, an ER-and lipid droplet-Associated protein, mediated VLDL lipidation and maturation by interacting with Apolipoprotein B, Jing Ye, John Zhong Li, Yang Liu, Xuanhe Li, Tianshu Yang, Xiaodong Ma, Qing Li, Zemin Yao, and Peng Li, 2009 Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient mice, Shen Yon Toh, Jingyi Gong, Guoli Du, John Zhong Li, Shuquan Yang, Jing Ye, Huilan Yao, Yinxin Zhang, Bofu Xue, Qing Li Hongyuan Yang, Zilong Wen, and Peng Li, 2008 Downregulation of AMP-activated protein kinase by Cidea-mediated ubiquitination and degradation in brown adipose tissue, Jingzong Qi, Jingyi Gong, Tongjin Zhao, Jie Zhao, Penny Lam, Jing Ye, John Zhong Li, Jiawei Wu, Hai-meng Zhou, and Peng Li, 2008 Cideb regulates diet-induced obesity, liver steatosis and insulin sensitivity by controlling lipogeneis and fatty acid oxidation, John Zhong Li, Jing Ye, Bofu Xue, Jingzong Qi, Jing Zhang, Zhihong Zhou, Qing Li, Zilong Wen and Peng Li, 2007

Areas of Focus

Molecular mechanisms of glucose and lipid metabolism regulation

Publications

The Patatin-Like Phospholipase Domain Containing Protein 7 Facilitates VLDL Secretion by Modulating ApoE Stability, Xiuyun Wang, Min Guo, Qian Wang, Qingjie Wang, Shasha Zuo, Xu Zhang, Hui Tong, Jizheng Chen, Huiming Wang, Xiaowei Chen, Junyuan Guo, Xiong Su, Hui Liang, Hongwen Zhou, John Zhong Li, 2020
The Metabolic Regulator Small Heterodimer Partner Contributes to the Glucose and Lipid Homeostasis Abnormalities Induced by Hepatitis C Virus Infection, Jizheng Chen, Yue Zhou, Yuan Zhuang, Tian Qin, Min Guo, Jing Jiang, Junqi Niu, John Zhong Li, Xinwen Chen, Qian Wang, 2019
Long non-coding RNA Bhmt-AS attenuates hepatic gluconeogenesis via modulation of Bhmt expression, Xuan Shen, Yajun Zhang, Xu Zhang, Yiwei Yao, Yujie Zheng, Xianwei Cui, Chang Liu, Qian Wang, John Zhong Li, 2019
New insight into inter-organ crosstalk contributing to the pathogenesis of non-alcoholic fatty liver disease (NAFLD), Xu Zhang, Xuetao Ji, Qian Wang, John Zhong Li, 2018
Differential Roles of Cell Death-inducing DNA Fragmentation Factor-α-like Effector (CIDE) Proteins in Promoting Lipid Droplet Fusion and Growth in Subpopulations of Hepatocytes, Wenyi Xu, Lizhen Wu, Miao Yu, Feng-Jung Chen, Muhammad Arshad, Xiayu Xia, Hao Ren, Jinhai Yu, Li Xu, Dijin Xu, John Zhong Li, Peng Li, and Linkang Zhou, 2016
Chronic overexpression of PNPLA3I148M in mouse liver causes hepatic steatosis, John Zhong Li, Yongcheng Huang, Ruchan Karaman, Pavlina T. Ivanova, H. Alex Brown, Thomas Roddy, Jose Castro-Perez, Jonathan C. Cohen, and Helen H. Hobbs, 2012
Pnpla3/Adiponutrin deficient in mice does not contribute to fatty liver disease or the metabolic syndrome, Mahesh K. Basantani Mitch T. Sitnick, Dani Brenner, Noah P. Gardner, John Zhong Li, Gabriele Schoiswohl, Kui Yang, Manju Kumari, Richard W Gross, Rudolf Zechner, and Erin E. Kershaw, 2011
Control of cholesterol biosynthesis, uptake and storage in hepatocytes by Cideb, John Zhong Li, Yao Lei, Yue Wang, Yinxin Zhang, Jing Ye, Xiayu Xia, Xianming Pan and Peng Li, 2010
A Feed-forward Loop Amplifies Nutritional Regulation of PNPLA3, Yongcheng Huang, Shaoqing He, John Zhong Li, Young-Kyo Seo, Timothy F. Osborne, Jonathan C. Cohen, and Helen H. Hobbs, 2010
A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis, Shaoqing He, Christopher McPhaul, John Zhong Li, Rita Garuti, Lisa Kinch, Nick V Grishin, Jonathan C. Cohen, and Helen H. Hobbs, 2010
Cideb, an ER-and lipid droplet-Associated protein, mediated VLDL lipidation and maturation by interacting with Apolipoprotein B, Jing Ye, John Zhong Li, Yang Liu, Xuanhe Li, Tianshu Yang, Xiaodong Ma, Qing Li, Zemin Yao, and Peng Li, 2009
Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient mice, Shen Yon Toh, Jingyi Gong, Guoli Du, John Zhong Li, Shuquan Yang, Jing Ye, Huilan Yao, Yinxin Zhang, Bofu Xue, Qing Li Hongyuan Yang, Zilong Wen, and Peng Li, 2008
Downregulation of AMP-activated protein kinase by Cidea-mediated ubiquitination and degradation in brown adipose tissue, Jingzong Qi, Jingyi Gong, Tongjin Zhao, Jie Zhao, Penny Lam, Jing Ye, John Zhong Li, Jiawei Wu, Hai-meng Zhou, and Peng Li, 2008
Cideb regulates diet-induced obesity, liver steatosis and insulin sensitivity by controlling lipogeneis and fatty acid oxidation, John Zhong Li, Jing Ye, Bofu Xue, Jingzong Qi, Jing Zhang, Zhihong Zhou, Qing Li, Zilong Wen and Peng Li, 2007

Glucose Metabolism Lipid Metabolism Molecular Mechanisms Regulation Obesity Diabetes Fatty Liver Disease Models Therapeutic Targets Protein Regulation

Guoheng Xu - Peking University

Jichun Yang - Peking University

Rui Chen - Wuhan University

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