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Hongkai Bi
Basic Medical Sciences
Nanjing Medical University
Jiangsu
Language: Chinese, English
Bacteria
Fatty Acids
Biotin
Metabolism
Helicobacter Pylori
Gastric Cancer
Drug Screening
Antibacterial
Mechanisms
Evaluation
Areas of Focus
- New mechanisms of bacterial fatty acid and biotin metabolism
- Mechanisms of Helicobacter pylori and gastric cancer development
- Screening and evaluation of novel antibacterial drugs
Work Experience
- 2009-2015 - University of Illinois at Urbana-Champaign - Postdoctoral Researcher
- 2015-present - Nanjing Medical University - Professor
Academic Background & Achievements
- 2006-2009: Doctoral Researcher at Chiba University, Japan
- Achievement: Published over 10 SCI papers as first or corresponding author
Publications
- Unsaturated Fatty Acid Synthesis in the Gastric Pathogen Helicobacter pylori Proceeds via a Backtracking Mechanism, Bi H*, Zhu L, Jia J, Zeng L, Cronan JE*, 2016
- A Biotin Biosynthesis Gene Restricted to Helicobacter, Bi H*, Zhu L, Jia J, Cronan JE*, 2016
- Comparative Genomics of H. pylori and Non-Pylori Helicobacter Species to Identify New Regions Associated with Its Pathogenicity and Adaptability, De-Min Cao, Qun-Feng Lu, Song-Bo Li, Ju-Ping Wang, Yu-Li Chen, Yan-Qiang Huang*, Hong-Kai Bi*, 2016
- Xanthomonas campestris RpfB is a Fatty Acyl-CoA Ligase Required to Counteract the Thioesterase Activity of the RpfF Diffusible Signal Factor (DSF) Synthase, Bi H, Yu Y, Dong H, Wang H, Cronan JE, 2014
- Inefficient Translation Renders the Enterococcus faecalis fabK Enoyl-ACP Reductase Phenotypically Cryptic, Bi H, Zhu L, Wang H, Cronan JE, 2014
- The two functional enoyl-acyl carrier protein reductases of Enterococcus faecalis do not mediate triclosan resistance, Zhu L#, Bi H#, Ma J, Hu Z, Zhang W, Cronan JE, Wang H, 2013
- FabQ, a dual-function dehydratase/isomerase, circumvents the last step of the classical fatty acid synthesis cycle, Bi H, Wang H, Cronan JE, 2013
Awards
- Jiangsu Distinguished Professor (2017)
