Areas of Focus
- Vascular and metabolic disease mechanisms
- Inflammation and immunity
Work Experience
- 2013-2015 - University of Pittsburgh School of Medicine, Postdoctoral Researcher
- Current - Central South University, Professor and Vice Director of the Department of Biochemistry and Molecular Biology
Academic Background & Achievements
- 2012 - PhD in Pathophysiology from Central South University
- Postdoctoral research at University of Pittsburgh School of Medicine (2013-2015)
- Led 2 national natural science funds, 2 key R&D plan projects in Hunan, and other provincial projects
Publications
- Research progress of endothelial-mesenchymal transition in diabetic kidney disease, Chen S*, 2022
- Glucolipotoxicity induces endothelial cell dysfunction by activating autophagy and inhibiting autophagic flow, Chen S*, 2022
- LKB1 Regulates Vascular Macrophage Functions in Atherosclerosis, Chen S*, 2021
- Vildagliptin improves high glucose-induced endothelial mitochondrial dysfunction via inhibiting mitochondrial fission, Chen S*, 2019
- S1PR2 antagonist ameliorate high glucose-induced fission and dysfunction of mitochondria in HRGECs via regulating ROCK1, Chen S*, 2019
- Palmitic acid-induced autophagy increases reactive oxygen species via the Ca2+/PKCα/NOX4 pathway and impairs endothelial function in human umbilical vein endothelial cells, Chen S*, 2019
- TWEAK/Fn14 promotes oxidative stress through AMPK/PGC‑1α/MnSOD signaling pathway in endothelial cells, Chen S*, 2018
- NK1.1+ cells promote sustained tissue injury and inflammation after trauma with hemorrhagic shock, Chen S, 2017
- Role of sphingosine-1-phosphate receptor 1 and sphingosine-1-phosphate receptor 2 in hyperglycemia-induced endothelial cell dysfunction, Chen S, 2015
- Severe multiple organ injury in HSF1 knockout mice induced by lipopolysaccharide is associated with an increase in neutrophil infiltration and surface expression of adhesion molecules, Chen S, 2012
Awards
- Second Prize in Natural Science of Hunan Province (3rd place)
- Second Prize for Excellent Academic Paper in Natural Science of Hunan Province (1st place)
