Professor | Xiaoyang Zhao | Asia Growth Partners

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Name	Xiaoyang Zhao
Contact Information	zhaoxiaoyang@smu.edu.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Xiaoyang Zhao

Contact Information

zhaoxiaoyang@smu.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Southern Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2004 - PhD: Institute of Zoology, Chinese Academy of Sciences Achievement: Published 26 papers in journals like Nature, Cell Stem Cell, Nature Cell Biology
Work Experience	2015-present - Southern Medical University - Professor 2011-2015 - Institute of Zoology, Chinese Academy of Sciences - Researcher
Awards	2021: National Natural Science Second Prize 2018: Zhongyuan Concord Life Medicine Innovation Breakthrough Award 2017: Stem Cell Young Researcher Award

University/Lab Affiliation and Title

Southern Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2004 - PhD: Institute of Zoology, Chinese Academy of Sciences
Achievement: Published 26 papers in journals like Nature, Cell Stem Cell, Nature Cell Biology

Work Experience

2015-present - Southern Medical University - Professor
2011-2015 - Institute of Zoology, Chinese Academy of Sciences - Researcher

Awards

2021: National Natural Science Second Prize
2018: Zhongyuan Concord Life Medicine Innovation Breakthrough Award
2017: Stem Cell Young Researcher Award

Areas of Focus	Stem Cells Developmental and Reproductive Medicine
Publications	Single-cell multi-omics sequencing of human spermatogenesis reveals a DNA demethylation event associated with male meiotic recombination, Huang YP, Li L, An G, Yang XY, Cui MM, Song XL, Lin J, Zhang XL, Yao ZK, Wan C, Zhou C, Zhao JX, Song K, Ren SF, Xia XY, Fu X, Lan Y, Hu XS, Wang W, Wang M, Zheng Y, Miao K, Bai XC, Hutchins AP, Chang G, Gao S, Zhao XY, 2023 Lovastatin Promotes the Self-renewal of Murine and Primate Spermatogonial Stem Cells, Li CH, Yao ZK, Ma LZ, Song XL, Wang W, Wan C, Ren SF, Chen DY, Zheng Y, Zhu YT, Chang G, Wu SH, Miao K, Luo F, Zhao XY, 2023 Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models, Song K, Yang XY, An G, Xia XY, Zhao JX, Xu XH, Wan C, Liu TY, Zheng Y, Ren SF, Wang M, Chang G, Shane Cronin, Josef Penninger, Jing T, Ou XH, Rao S, Liu ZT, Zhao XY, 2022 The Chemical Reprogramming of Unipotent Adult Germ Cells towards Authentic Pluripotency and de novo Establishment of Imprinting, Chen YH, Lu JS, Xu YW, Huang YP, Wang DZ, Liang PL, Ren SF, Hu XS, Qin YW, Ke W, Jauch R, Hutchins AP, Wang M, Tang FC, Zhao XY, 2023 Single-cell multi-omics sequencing reveals the reprogramming defects in embryos generated by round spermatid injection, Wang J, Zhou C, Gao S, Song XL, Yang XY, Fan JQ, Ren SF, Ma LZ, Zhao JX, Cui MM, Song K, Wang M, Li CH, Zheng Y, Luo F, Miao K, Bai XC, Hutchins AP, Li L, Chang G, Zhao XY, 2022 Cell-fate transition and determination analysis of mouse male germ cells throughout development, Zhao JX, Lu P, Wan C, Huang YP, Cui MM, Yang XY, Hu YQ, Zheng Y, Dong J, Wang M, Zhang S, Liu ZT, Bian SH, Wang XM, Wang R, Ren SF, Wang DZ, Yao ZK, Chang G, Tang FC, Zhao XY, 2021 CellCall: Integrating paired ligand-receptor and transcription factor activities for cell-cell communication, Zhang Y, Liu TY, Hu XS, Wang M, Wang J, Zou BH, Tan PW, Cui TY, Dou YY, Ning L, Huang Y, Rao S, Wang D, Zhao XY, 2021 The Chromatin Accessibility Landscape Reveals Distinct Transcriptional Regulation in the Generation of Human Primordial Germ Cell-Like Cells from Pluripotent Stem Cells, Wang XM, Veerapandian V, Yang XY, Song K, Xu XH, Cui MM, Yuan WY, Huang YP, Xia XY, Yao ZK, Wan C, Luo F, Song XL, Wang XR, Zheng Y, Hutchins AP, Jauch R, Liang MY, Wang CH, Liu ZT, Chang G, Zhao XY, 2021 Single-Cell RNA Sequencing Analysis Reveals Sequential Cell Fate Transition during Human Spermatogenesis, Wang M, Liu X, Chang G, Chen Y, An G, Yan L, Gao S, Xu Y, Cui Y, Dong J, Chen Y, Fan X, Hu Y, Song K, Zhu X, Gao Y, Yao Z, Bian S, Hou Y, Lu J, Wang R, Fan Y, Lian Y, Tang W, Wang Y, Liu J, Zhao L, Wang L, Liu Z, Yuan R, Shi Y, Hu B, Ren X, Tang F, Zhao XY, Qiao J, 2018 Complete meiosis from ES-cell derived germ cells in vitro, Zhou Q, Wang M, Yuan Y, Wang W, Fu R, Wan H, Xie M, Liu M, Guo X, Zheng Y, Feng G, Shi Q, Zhao XY, Sha J, Zhou Q, 2016 Androgenetic haploid embryonic stem cells produce live transgenic mice, Li W, Shuai L, Wan HF, Dong MZ, Wang M, Sang LS, Feng CJ, Luo GZ, Li TD, Li X, Wang L, Zheng QY, Sheng C, Wu HJ, Liu Z, Liu L, Wang XJ, Zhao XY, Zhou Q, 2012 iPS cells produce viable mice through tetraploid complementation, Zhao XY, Li W, Lv Z, Liu L, Tong M, Hai T, Hao J, Guo CL, Ma QW, Wang L, Zeng FY, Zhou Q, 2009

Areas of Focus

Stem Cells
Developmental and Reproductive Medicine

Publications

Single-cell multi-omics sequencing of human spermatogenesis reveals a DNA demethylation event associated with male meiotic recombination, Huang YP, Li L, An G, Yang XY, Cui MM, Song XL, Lin J, Zhang XL, Yao ZK, Wan C, Zhou C, Zhao JX, Song K, Ren SF, Xia XY, Fu X, Lan Y, Hu XS, Wang W, Wang M, Zheng Y, Miao K, Bai XC, Hutchins AP, Chang G, Gao S, Zhao XY, 2023
Lovastatin Promotes the Self-renewal of Murine and Primate Spermatogonial Stem Cells, Li CH, Yao ZK, Ma LZ, Song XL, Wang W, Wan C, Ren SF, Chen DY, Zheng Y, Zhu YT, Chang G, Wu SH, Miao K, Luo F, Zhao XY, 2023
Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models, Song K, Yang XY, An G, Xia XY, Zhao JX, Xu XH, Wan C, Liu TY, Zheng Y, Ren SF, Wang M, Chang G, Shane Cronin, Josef Penninger, Jing T, Ou XH, Rao S, Liu ZT, Zhao XY, 2022
The Chemical Reprogramming of Unipotent Adult Germ Cells towards Authentic Pluripotency and de novo Establishment of Imprinting, Chen YH, Lu JS, Xu YW, Huang YP, Wang DZ, Liang PL, Ren SF, Hu XS, Qin YW, Ke W, Jauch R, Hutchins AP, Wang M, Tang FC, Zhao XY, 2023
Single-cell multi-omics sequencing reveals the reprogramming defects in embryos generated by round spermatid injection, Wang J, Zhou C, Gao S, Song XL, Yang XY, Fan JQ, Ren SF, Ma LZ, Zhao JX, Cui MM, Song K, Wang M, Li CH, Zheng Y, Luo F, Miao K, Bai XC, Hutchins AP, Li L, Chang G, Zhao XY, 2022
Cell-fate transition and determination analysis of mouse male germ cells throughout development, Zhao JX, Lu P, Wan C, Huang YP, Cui MM, Yang XY, Hu YQ, Zheng Y, Dong J, Wang M, Zhang S, Liu ZT, Bian SH, Wang XM, Wang R, Ren SF, Wang DZ, Yao ZK, Chang G, Tang FC, Zhao XY, 2021
CellCall: Integrating paired ligand-receptor and transcription factor activities for cell-cell communication, Zhang Y, Liu TY, Hu XS, Wang M, Wang J, Zou BH, Tan PW, Cui TY, Dou YY, Ning L, Huang Y, Rao S, Wang D, Zhao XY, 2021
The Chromatin Accessibility Landscape Reveals Distinct Transcriptional Regulation in the Generation of Human Primordial Germ Cell-Like Cells from Pluripotent Stem Cells, Wang XM, Veerapandian V, Yang XY, Song K, Xu XH, Cui MM, Yuan WY, Huang YP, Xia XY, Yao ZK, Wan C, Luo F, Song XL, Wang XR, Zheng Y, Hutchins AP, Jauch R, Liang MY, Wang CH, Liu ZT, Chang G, Zhao XY, 2021
Single-Cell RNA Sequencing Analysis Reveals Sequential Cell Fate Transition during Human Spermatogenesis, Wang M, Liu X, Chang G, Chen Y, An G, Yan L, Gao S, Xu Y, Cui Y, Dong J, Chen Y, Fan X, Hu Y, Song K, Zhu X, Gao Y, Yao Z, Bian S, Hou Y, Lu J, Wang R, Fan Y, Lian Y, Tang W, Wang Y, Liu J, Zhao L, Wang L, Liu Z, Yuan R, Shi Y, Hu B, Ren X, Tang F, Zhao XY, Qiao J, 2018
Complete meiosis from ES-cell derived germ cells in vitro, Zhou Q, Wang M, Yuan Y, Wang W, Fu R, Wan H, Xie M, Liu M, Guo X, Zheng Y, Feng G, Shi Q, Zhao XY, Sha J, Zhou Q, 2016
Androgenetic haploid embryonic stem cells produce live transgenic mice, Li W, Shuai L, Wan HF, Dong MZ, Wang M, Sang LS, Feng CJ, Luo GZ, Li TD, Li X, Wang L, Zheng QY, Sheng C, Wu HJ, Liu Z, Liu L, Wang XJ, Zhao XY, Zhou Q, 2012
iPS cells produce viable mice through tetraploid complementation, Zhao XY, Li W, Lv Z, Liu L, Tong M, Hai T, Hao J, Guo CL, Ma QW, Wang L, Zeng FY, Zhou Q, 2009

Stem Cells Development Reproduction Infertility Spermatogenesis Organoids Genomics Cell Biology Biotechnology Regenerative Medicine

Jun Xu - Peking University

Cai-Ping Ren - Central South University

Liang Hu - Central South University

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