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Cunyou Zhao
Basic Medical Sciences
Southern Medical University
Guangdong
Language: English, Chinese
Genetics
Epigenetics
Schizophrenia
Dna Methylation
Noncoding Rna
Neural Circuits
Psychiatric Disorders
Phenotypic Variation
Allele-Specific
Ipscs
Areas of Focus
- Epigenetic regulation and neural circuit mechanisms of susceptibility in major psychiatric disorders
Work Experience
- 2011.9 - Present - Southern Medical University (Guangzhou) - Professor, Doctoral Supervisor
- 2009.6 - 2011.9 - Hong Kong University of Science and Technology (Hong Kong) - Postdoctoral Associate Researcher, Research Assistant Professor
- 2003.7 - 2004.8 - Hong Kong University of Science and Technology (Hong Kong) - Assistant Researcher
- 2000.7 - 2003.6 - Institute of Microbiology, Chinese Academy of Sciences (Beijing) - Assistant Researcher
Academic Background & Achievements
- 2008 - PhD in Bioengineering: Hong Kong University of Science and Technology
- 2010 - Ministry of Education Natural Science Second Prize (3rd contributor)
Publications
- Transition of allele-specific DNA hydroxymethylation at regulatory loci is associated with phenotypic variation in monozygotic twins discordant for psychiatric disorders., Ye, J., Z. Huang, Q. Li, Z. Li, Y. Lan, Z. Wang, C. Ni, X. Wu, T. Jiang, Y. Li, Q. Yang, J. Lim, C. Ren, M. Jiang, S. Li, P. Jin, J. Chen* and C. Zhao*, 2023
- Loss of schizophrenia-related miR-501-3p in mice impairs sociability and memory by enhancing mGluR5-mediated glutamatergic transmission., Liang, W., Y. Hou, W. Huang, Y. Wang, T. Jiang, X. Huang, Z. Wang, F. Wu, J. Zheng, J. Zhang, H. Ou, S. Li, J. Ping, Y. Zhang, J. Ye, Z. Li, Q. Yang, J. Zhang, X. Zheng, S. Li, X. Zhu, R. Chen* and C. Zhao*, 2022
- Allele-specific DNA methylation maps in monozygotic twins discordant for psychiatric disorders reveal that disease-associated switching at the EIPR1 regulatory loci modulates neural function., Li, Q., Z. Wang, L. Zong, L. Ye, J. Ye, H. Ou, T. Jiang, B. Guo, Q. Yang, W. Liang, J. Zhang, Y. Long, X. Zheng, Y. Hou, F. Wu, L. Zhou, S. Li, X. Huang, and C. Zhao*, 2021
- LncRNA-AC006129.1 reactivates a SOCS3-mediated anti-inflammatory response through DNA methylation-mediated CIC downregulation in schizophrenia., Ni, C., W. Jiang, Z. Wang, Z. Wang, J. Zhang, X. Zheng, Z. Liu, H. Ou, T. Jiang, W. Liang, F. Wu, Q. Li, Y. Hou, Q. Yang, B. Guo, S. Liu, S. Li, S. Li, E. Yang, X.H. Zhu, X. Huang, Z. Wen, and C. Zhao*, 2021
- Imprinting in the schizophrenia candidate gene GABRB2 encoding GABA(A) receptor beta(2) subunit., Pun, F.W., C. Zhao, W.S. Lo, S.K. Ng, S.Y. Tsang, V. Nimgaonkar, W.S. Chung, G.S. Ungvari, and H. Xue, 2011
- Two isoforms of GABA(A) receptor beta2 subunit with different electrophysiological properties: Differential expression and genotypical correlations in schizophrenia., Zhao, C., Z. Xu, J. Chen, Z. Yu, K.L. Tong, W.S. Lo, F.W. Pun, S.K. Ng, S.Y. Tsang, and H. Xue, 2006
- Variation in global DNA hydroxymethylation with age associated with schizophrenia., Jiang, T., L. Zong, L. Zhou, Y. Hou, L. Zhang, X. Zheng, H. Han, S. Li, W. Zhang, J. Zhang, C. Deng, Y. Jia, and C. Zhao*, 2017
- Epigenetic inactivation of ERF reactivates gamma-globin expression in beta-thalassemia., Bao, X., X. Zhang, L. Wang, Z. Wang, J. Huang, Q. Zhang, Y. Ye, Y. Liu, D. Chen, Y. Zuo, Q. Liu, P. Xu, B. Huang, J. Fang, J. Lao, X. Feng, Y. Li, R. Kurita, Y. Nakamura, W. Yu, C. Ju, C. Huang, N. Mohandas, D. Li, C. Zhao*, and X. Xu*, 2021
- A Genetic Variant Ameliorates beta-Thalassemia Severity by Epigenetic-Mediated Elevation of Human Fetal Hemoglobin Expression., Chen, D., Y. Zuo, X. Zhang, Y. Ye, X. Bao, H. Huang, W. Tepakhan, L. Wang, J. Ju, G. Chen, M. Zheng, D. Liu, S. Huang, L. Zong, C. Li, Y. Chen, C. Zheng, L. Shi, Q. Zhao, Q. Wu, S. Fucharoen, C. Zhao*, and X. Xu*, 2017
- Epigenetic age acceleration was delayed in schizophrenia., Wu, X., J. Ye, Z. Wang, and C. Zhao*, 2021
- DNA methylation patterns of β-globin cluster in β-thalassemia patients., Bao, X., Y. Zuo, D. Chen, and C. Zhao*, 2020
Awards
- 2010 - Ministry of Education Natural Science Second Prize (3rd contributor)
