Professor | Cunyou Zhao | Asia Growth Partners

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Name	Cunyou Zhao
Contact Information	cyzhao@smu.edu.cn
Language ability	English, Chinese
Province	Guangdong

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Name

Cunyou Zhao

Contact Information

cyzhao@smu.edu.cn

Language ability

English, Chinese

Province

Guangdong

University/Lab Affiliation and Title	Southern Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2008 - PhD in Bioengineering: Hong Kong University of Science and Technology 2010 - Ministry of Education Natural Science Second Prize (3rd contributor)
Work Experience	2011.9 - Present - Southern Medical University (Guangzhou) - Professor, Doctoral Supervisor 2009.6 - 2011.9 - Hong Kong University of Science and Technology (Hong Kong) - Postdoctoral Associate Researcher, Research Assistant Professor 2003.7 - 2004.8 - Hong Kong University of Science and Technology (Hong Kong) - Assistant Researcher 2000.7 - 2003.6 - Institute of Microbiology, Chinese Academy of Sciences (Beijing) - Assistant Researcher
Awards	2010 - Ministry of Education Natural Science Second Prize (3rd contributor)

University/Lab Affiliation and Title

Southern Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2008 - PhD in Bioengineering: Hong Kong University of Science and Technology
2010 - Ministry of Education Natural Science Second Prize (3rd contributor)

Work Experience

2011.9 - Present - Southern Medical University (Guangzhou) - Professor, Doctoral Supervisor
2009.6 - 2011.9 - Hong Kong University of Science and Technology (Hong Kong) - Postdoctoral Associate Researcher, Research Assistant Professor
2003.7 - 2004.8 - Hong Kong University of Science and Technology (Hong Kong) - Assistant Researcher
2000.7 - 2003.6 - Institute of Microbiology, Chinese Academy of Sciences (Beijing) - Assistant Researcher

Awards

2010 - Ministry of Education Natural Science Second Prize (3rd contributor)

Areas of Focus	Epigenetic regulation and neural circuit mechanisms of susceptibility in major psychiatric disorders
Publications	Transition of allele-specific DNA hydroxymethylation at regulatory loci is associated with phenotypic variation in monozygotic twins discordant for psychiatric disorders., Ye, J., Z. Huang, Q. Li, Z. Li, Y. Lan, Z. Wang, C. Ni, X. Wu, T. Jiang, Y. Li, Q. Yang, J. Lim, C. Ren, M. Jiang, S. Li, P. Jin, J. Chen* and C. Zhao, 2023 Loss of schizophrenia-related miR-501-3p in mice impairs sociability and memory by enhancing mGluR5-mediated glutamatergic transmission., Liang, W., Y. Hou, W. Huang, Y. Wang, T. Jiang, X. Huang, Z. Wang, F. Wu, J. Zheng, J. Zhang, H. Ou, S. Li, J. Ping, Y. Zhang, J. Ye, Z. Li, Q. Yang, J. Zhang, X. Zheng, S. Li, X. Zhu, R. Chen and C. Zhao, 2022 Allele-specific DNA methylation maps in monozygotic twins discordant for psychiatric disorders reveal that disease-associated switching at the EIPR1 regulatory loci modulates neural function., Li, Q., Z. Wang, L. Zong, L. Ye, J. Ye, H. Ou, T. Jiang, B. Guo, Q. Yang, W. Liang, J. Zhang, Y. Long, X. Zheng, Y. Hou, F. Wu, L. Zhou, S. Li, X. Huang, and C. Zhao, 2021 LncRNA-AC006129.1 reactivates a SOCS3-mediated anti-inflammatory response through DNA methylation-mediated CIC downregulation in schizophrenia., Ni, C., W. Jiang, Z. Wang, Z. Wang, J. Zhang, X. Zheng, Z. Liu, H. Ou, T. Jiang, W. Liang, F. Wu, Q. Li, Y. Hou, Q. Yang, B. Guo, S. Liu, S. Li, S. Li, E. Yang, X.H. Zhu, X. Huang, Z. Wen, and C. Zhao, 2021 Imprinting in the schizophrenia candidate gene GABRB2 encoding GABA(A) receptor beta(2) subunit., Pun, F.W., C. Zhao, W.S. Lo, S.K. Ng, S.Y. Tsang, V. Nimgaonkar, W.S. Chung, G.S. Ungvari, and H. Xue, 2011 Two isoforms of GABA(A) receptor beta2 subunit with different electrophysiological properties: Differential expression and genotypical correlations in schizophrenia., Zhao, C., Z. Xu, J. Chen, Z. Yu, K.L. Tong, W.S. Lo, F.W. Pun, S.K. Ng, S.Y. Tsang, and H. Xue, 2006 Variation in global DNA hydroxymethylation with age associated with schizophrenia., Jiang, T., L. Zong, L. Zhou, Y. Hou, L. Zhang, X. Zheng, H. Han, S. Li, W. Zhang, J. Zhang, C. Deng, Y. Jia, and C. Zhao, 2017 Epigenetic inactivation of ERF reactivates gamma-globin expression in beta-thalassemia., Bao, X., X. Zhang, L. Wang, Z. Wang, J. Huang, Q. Zhang, Y. Ye, Y. Liu, D. Chen, Y. Zuo, Q. Liu, P. Xu, B. Huang, J. Fang, J. Lao, X. Feng, Y. Li, R. Kurita, Y. Nakamura, W. Yu, C. Ju, C. Huang, N. Mohandas, D. Li, C. Zhao, and X. Xu, 2021 A Genetic Variant Ameliorates beta-Thalassemia Severity by Epigenetic-Mediated Elevation of Human Fetal Hemoglobin Expression., Chen, D., Y. Zuo, X. Zhang, Y. Ye, X. Bao, H. Huang, W. Tepakhan, L. Wang, J. Ju, G. Chen, M. Zheng, D. Liu, S. Huang, L. Zong, C. Li, Y. Chen, C. Zheng, L. Shi, Q. Zhao, Q. Wu, S. Fucharoen, C. Zhao, and X. Xu, 2017 Epigenetic age acceleration was delayed in schizophrenia., Wu, X., J. Ye, Z. Wang, and C. Zhao, 2021 DNA methylation patterns of β-globin cluster in β-thalassemia patients., Bao, X., Y. Zuo, D. Chen, and C. Zhao, 2020

Areas of Focus

Epigenetic regulation and neural circuit mechanisms of susceptibility in major psychiatric disorders

Publications

Transition of allele-specific DNA hydroxymethylation at regulatory loci is associated with phenotypic variation in monozygotic twins discordant for psychiatric disorders., Ye, J., Z. Huang, Q. Li, Z. Li, Y. Lan, Z. Wang, C. Ni, X. Wu, T. Jiang, Y. Li, Q. Yang, J. Lim, C. Ren, M. Jiang, S. Li, P. Jin, J. Chen* and C. Zhao*, 2023
Loss of schizophrenia-related miR-501-3p in mice impairs sociability and memory by enhancing mGluR5-mediated glutamatergic transmission., Liang, W., Y. Hou, W. Huang, Y. Wang, T. Jiang, X. Huang, Z. Wang, F. Wu, J. Zheng, J. Zhang, H. Ou, S. Li, J. Ping, Y. Zhang, J. Ye, Z. Li, Q. Yang, J. Zhang, X. Zheng, S. Li, X. Zhu, R. Chen* and C. Zhao*, 2022
Allele-specific DNA methylation maps in monozygotic twins discordant for psychiatric disorders reveal that disease-associated switching at the EIPR1 regulatory loci modulates neural function., Li, Q., Z. Wang, L. Zong, L. Ye, J. Ye, H. Ou, T. Jiang, B. Guo, Q. Yang, W. Liang, J. Zhang, Y. Long, X. Zheng, Y. Hou, F. Wu, L. Zhou, S. Li, X. Huang, and C. Zhao*, 2021
LncRNA-AC006129.1 reactivates a SOCS3-mediated anti-inflammatory response through DNA methylation-mediated CIC downregulation in schizophrenia., Ni, C., W. Jiang, Z. Wang, Z. Wang, J. Zhang, X. Zheng, Z. Liu, H. Ou, T. Jiang, W. Liang, F. Wu, Q. Li, Y. Hou, Q. Yang, B. Guo, S. Liu, S. Li, S. Li, E. Yang, X.H. Zhu, X. Huang, Z. Wen, and C. Zhao*, 2021
Imprinting in the schizophrenia candidate gene GABRB2 encoding GABA(A) receptor beta(2) subunit., Pun, F.W., C. Zhao, W.S. Lo, S.K. Ng, S.Y. Tsang, V. Nimgaonkar, W.S. Chung, G.S. Ungvari, and H. Xue, 2011
Two isoforms of GABA(A) receptor beta2 subunit with different electrophysiological properties: Differential expression and genotypical correlations in schizophrenia., Zhao, C., Z. Xu, J. Chen, Z. Yu, K.L. Tong, W.S. Lo, F.W. Pun, S.K. Ng, S.Y. Tsang, and H. Xue, 2006
Variation in global DNA hydroxymethylation with age associated with schizophrenia., Jiang, T., L. Zong, L. Zhou, Y. Hou, L. Zhang, X. Zheng, H. Han, S. Li, W. Zhang, J. Zhang, C. Deng, Y. Jia, and C. Zhao*, 2017
Epigenetic inactivation of ERF reactivates gamma-globin expression in beta-thalassemia., Bao, X., X. Zhang, L. Wang, Z. Wang, J. Huang, Q. Zhang, Y. Ye, Y. Liu, D. Chen, Y. Zuo, Q. Liu, P. Xu, B. Huang, J. Fang, J. Lao, X. Feng, Y. Li, R. Kurita, Y. Nakamura, W. Yu, C. Ju, C. Huang, N. Mohandas, D. Li, C. Zhao*, and X. Xu*, 2021
A Genetic Variant Ameliorates beta-Thalassemia Severity by Epigenetic-Mediated Elevation of Human Fetal Hemoglobin Expression., Chen, D., Y. Zuo, X. Zhang, Y. Ye, X. Bao, H. Huang, W. Tepakhan, L. Wang, J. Ju, G. Chen, M. Zheng, D. Liu, S. Huang, L. Zong, C. Li, Y. Chen, C. Zheng, L. Shi, Q. Zhao, Q. Wu, S. Fucharoen, C. Zhao*, and X. Xu*, 2017
Epigenetic age acceleration was delayed in schizophrenia., Wu, X., J. Ye, Z. Wang, and C. Zhao*, 2021
DNA methylation patterns of β-globin cluster in β-thalassemia patients., Bao, X., Y. Zuo, D. Chen, and C. Zhao*, 2020

Genetics Epigenetics Schizophrenia Dna Methylation Noncoding Rna Neural Circuits Psychiatric Disorders Phenotypic Variation Allele-Specific Ipscs

Zuping Zhang - Central South University

Xia Meng - Zhejiang University

Pengxu Qian - Zhejiang University

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