Professor | Xueming Wang | Asia Growth Partners

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Name	Xueming Wang
Contact Information	xmwang@smu.edu.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Xueming Wang

Contact Information

xmwang@smu.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Southern Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2001 - PhD in Neuropharmacology: Sun Yat-sen University

University/Lab Affiliation and Title

Southern Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2001 - PhD in Neuropharmacology: Sun Yat-sen University

Areas of Focus	Research on the pathogenesis of neurodegenerative diseases Research on the comorbidity mechanisms of metabolic diseases and neurological diseases Research on the mechanisms of neurite outgrowth
Publications	Retinoic acid receptor gamma is targeted by microRNA-124 and inhibits neurite outgrowth, Su X, Gu X, Zhang Z, Li W, Wang X, 2020 Inhibition of SIRT2 by Targeting GSK3β-Mediated Phosphorylation Alleviates SIRT2 Toxicity in SH-SY5Y Cells, Liu S, Zhou Z, Zhang L, Meng S, Li S, and Wang X, 2019 High-fat diet mediates anxiolytic-like behaviors in a time-dependent manner through the regulation of SIRT1 in the brain, Xu L#, Xu S#, Lin L, Gu X, Fu C, Fang Y, Li X, Wang X, 2018 miR-124 and miR-9 mediated downregulation of HDAC5 promotes neurite development through activating MEF2C-GPM6A pathway, Gu X, Fu C, Lin L, Liu S, Su X, Li A, Wu Q, Jia C, Zhang P, Chen L, Zhu X, Wang X, 2017 MicroRNA124 Regulated Neurite Elongation by Targeting OSBP, Gu X#, Li A#, Liu S, Lin L, Xu S, Zhang P,Li S; Li X; Tian B, Zhu X,Wang X, 2016 Soluble Epoxide Hydrolase Deficiency or Inhibition Attenuates MPTP-Induced Parkinsonism, Qin X#, Wu Q#, Lin L, Sun A, Liu S, Li X, Cao X, Gao T, Luo P, Zhu X, Wang X, 2015 Peroxisome proliferator-activated receptor γ is inhibited by histone deacetylase 4 in cortical neurons under oxidative stress, Yang Y, Qin X, Liu S, Li J, Zhu X, Gao T, Wang X, 2011 Phosphorylation of Neuronal Survival Factor, MEF2D by Glycogen Synthase Kinase 3 beta in Neuronal Apoptosis, Wang X#（共同一作）, She H#, Mao Z, 2009 Cyclin-dependent kinase 5 mediates neurotoxin-induced degradation of the transcription factormyocyte enhancer factor 2, Tang X#, Wang X#(共同一作), Gong X, Tong M, Park D,Mao Z, 2005 Regulation of neuroprotective activity of myocyte-enhancer factor 2 by cAMP-protein kinase A signaling pathway in neuronal survival, Wang X#（共同一作）, Tang X#, Li M, Marshall J, Mao Z, 2005 Regulation of hepatic stellate cell activation and growth by transcription factor myocyte enhancer factor 2, Wang X, Tang X, Gong X, Albanis E, Friedman SL, Mao Z*, 2004

Areas of Focus

Research on the pathogenesis of neurodegenerative diseases
Research on the comorbidity mechanisms of metabolic diseases and neurological diseases
Research on the mechanisms of neurite outgrowth

Publications

Retinoic acid receptor gamma is targeted by microRNA-124 and inhibits neurite outgrowth, Su X, Gu X, Zhang Z, Li W, Wang X*, 2020
Inhibition of SIRT2 by Targeting GSK3β-Mediated Phosphorylation Alleviates SIRT2 Toxicity in SH-SY5Y Cells, Liu S, Zhou Z, Zhang L, Meng S, Li S, and Wang X*, 2019
High-fat diet mediates anxiolytic-like behaviors in a time-dependent manner through the regulation of SIRT1 in the brain, Xu L#, Xu S#, Lin L, Gu X, Fu C, Fang Y, Li X, Wang X*, 2018
miR-124 and miR-9 mediated downregulation of HDAC5 promotes neurite development through activating MEF2C-GPM6A pathway, Gu X, Fu C, Lin L, Liu S, Su X, Li A, Wu Q, Jia C, Zhang P, Chen L, Zhu X, Wang X*, 2017
MicroRNA124 Regulated Neurite Elongation by Targeting OSBP, Gu X#, Li A#, Liu S, Lin L, Xu S, Zhang P,Li S; Li X; Tian B, Zhu X,Wang X*, 2016
Soluble Epoxide Hydrolase Deficiency or Inhibition Attenuates MPTP-Induced Parkinsonism, Qin X#, Wu Q#, Lin L, Sun A, Liu S, Li X, Cao X, Gao T, Luo P, Zhu X, Wang X*, 2015
Peroxisome proliferator-activated receptor γ is inhibited by histone deacetylase 4 in cortical neurons under oxidative stress, Yang Y, Qin X, Liu S, Li J, Zhu X, Gao T, Wang X*, 2011
Phosphorylation of Neuronal Survival Factor, MEF2D by Glycogen Synthase Kinase 3 beta in Neuronal Apoptosis, Wang X#（共同一作）, She H#, Mao Z*, 2009
Cyclin-dependent kinase 5 mediates neurotoxin-induced degradation of the transcription factormyocyte enhancer factor 2, Tang X#, Wang X#(共同一作), Gong X, Tong M, Park D,Mao Z*, 2005
Regulation of neuroprotective activity of myocyte-enhancer factor 2 by cAMP-protein kinase A signaling pathway in neuronal survival, Wang X#（共同一作）, Tang X#, Li M, Marshall J, Mao Z*, 2005
Regulation of hepatic stellate cell activation and growth by transcription factor myocyte enhancer factor 2, Wang X, Tang X, Gong X, Albanis E, Friedman SL, Mao Z*, 2004

Ppargamma Neurodegenerative Disease Metabolism Disease Neurite Outgrowth Transcription Factor Neuronal Survival Molecular Mechanisms High-Fat Diet Metabolic Syndrome Depression

Ma Rong Fang - Zhejiang University

Wang Yiqun - Fudan University

Ming Lu - Nanjing Medical University

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