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Xin Luo
Basic Medical Sciences
Southern Medical University
Guangdong
Language: English, Chinese
Chronic Pain
Neuroimmune Interaction
Macrophage
Sensory Neurons
Pathological Pain
Molecular Mechanisms
Tissue Repair
Anesthetic Drugs
Immune Cells
Peripheral Nervous System
Areas of Focus
- Mechanisms of sensory neuron-immune interaction in chronic pain
- Mechanisms of sensory neuron-immune interaction in tissue injury repair
- Sensory neuron mechanisms of anesthetic drug function
Academic Background & Achievements
- PhD: Department of Anesthesiology, Li Ka Shing Faculty of Medicine, University of Hong Kong
- Postdoctoral: Department of Anesthesiology, Duke University Medical Center, USA
- Published over 30 SCI papers
- First or corresponding author in 11 papers in journals like Neuron, Nature Communications
Publications
- Sex Differences in Pain with Emphasis on Neuroimmune Interactions, Xin Luo, Jasmine Ji, Ru-Rong Ji, 2023
- IL-23/IL-17A/TRPV1 Axis Produces Mechanical Pain via Macrophage-Sensory Neuron Crosstalk in Female Mice, Xin Luo, Ouyang Chen, Zilong Wang, Sangsu Bang, Jasmine Ji, Sang Hoon Lee, Yul Huh, Kenta Furutani, Qianru He, Xueshu Tao, Mei-Chuan Ko, Andrey Bortsov, Christopher R Donnelly, Yong Chen, Andrea Nackley, Temugin Berta, Ru-Rong Ji, 2021
- Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice, Sangsu Bang, Christopher R Donnelly, Xin Luo, Maria Toro Moreno, Xueshu Tao, Zilong Wang, Sharat Chandra, Andrey V Bortsov, Emily R. Derbyshire, Ru-Rong Ji, 2021
- Innate-Immune Sensing by Nociceptors IL-23 Enhances C-Fiber-Mediated and Blue Light-Induced Spontaneous Pain in Female Mice, Jasmine Ji, Qianru He, Xin Luo, Sangsu Bang, Aidan Mcginnis, Andrea G Nackley, Ru-Rong Ji, 2021
- STING controls nociception via type I interferon signaling in sensory neurons, Christopher R Donnelly, Changyu Jiang, Amanda S Andriessen, Kaiyuan Wang, Zilong Wang, Huiping Ding, Junli Zhao, Xin Luo, Michael S Lee, Yu L Lei, William Maixner, Mei-Chuan Ko, Ru-Rong Ji, 2021
- Macrophage TLR9 Contributes to Chemotherapy-induced Neuropathic Pain in Male Mice, Xin Luo, Yul Hul, Sangsu Bang, Qianru He, Linlin Zhang, Megumi Matsuda, Ru-Rong Ji, 2019
- Resolvin D5 inhibits neuropathic pain and inflammatory pain in male but not female mice: Distinct sex-dependence of D-series resolvins in pain regulation, Xin Luo, Yun Gu, Xueshu Tao, Charles N Serhan, Ru-Rong Ji, 2019
- Intrathecal administration of antisense oligonucleotide against p38α but not p38β MAP kinase isoform reduces neuropathic and postoperative pain and TLR4-induced pain in male mice, Xin Luo, Bethany Fitzsimmons, Apoorva Mohan, Linlin Zhang, Niccolo Terrando, Holly Kordasiewicz, Ru-Rong Ji, 2018
Awards
- 2018: Outstanding Reviewer by Neural Regeneration Research
